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Original Article
Cardiovascular Effects of Growth Hormone Treatment in Idiopathic Short Stature
Hyang Ok Woo, Dong Wook Kim
Clin Exp Pediatr. 1997;40(8):1149-1155.   Published online August 15, 1997
Purpose : An excess of GH causes various problems within the cardiovascular system including cardiac hypertrophy and abnormalities of left ventricle(LV) function. To evaluate the cardiovascular effects due to GH treatment in idiopathic short stature (ISS), we measured the cardiovascular function. Methods : Twenty-two echocardiographic studies were performed in ISS who were admitted from Jan. 1994 through Jul. 1996, and they were divided into two...
Seizure Types and EEG Findings of Juvenile Onset Idiopathic Generalized Epilepsy
Hyunmi Kim, Won Seop Kim, Jong Shin Kim, Kangho Cho, Ki Joong Kim, Yong Seung Hwang
Clin Exp Pediatr. 1997;40(7):991-998.   Published online July 15, 1997
Purpose : Juvenile myoclonic epilepsy, juvenile absence epilepsy, and epilepsy wth generalized tonic clonic seizure(GTCS) on awakening are the three syndromes of idiopathic generalized epilepsy of adolescent onset currently included in the classification of epilepsy syndromes of the International League Against Epilepsy(ILAE). Although they differ in their predominant seizure types, the syndromes share several seizure types. Also, there are no unique electrophysiologic or genetic markers....
Case Report
A Case of Intestinal Neuronal Dysplasia
Se Young Kim, Yon Ho Choe, Jeong Kee Seo, In One Kim, Chong Jai Kim
Clin Exp Pediatr. 1996;39(8):1151-1157.   Published online August 15, 1996
Intestinal neuronal dysplasia(IND) is a disease characterized clinically by symptoms of intestinal obstruction and pathologically by hyperplasia of the submucosal and myenteric plexuses with formation of giant ganglia. Chronic intestinal pseudo-obstruction is a clinical diagnosis, composed of myopathic form and neuropathic form, and normal intestinal histology. Intestinal neuronal dysplasia is a neuropathic form of chronic intestinal pseudo-obstruction. The clinical presentation and the course of IND...
A Case of Idiopathic Pulmonary Hemosiderosis
Chang Sung Lim, Seung Kyu Park, Won Park, Soon Jeong Lee, Chul Zoo Jung
Clin Exp Pediatr. 1996;39(1):136-141.   Published online January 15, 1996
Idiopathic pulmonary hemosiderosis is characterized by cough, hemoptysis, dyspnea, diffuse pulmonary infiltrates, and microcytic and hypochromic anemia. The cause of this illness is unknown. We experienced a case of idiopathic pulmonary hemosiderosis in a 2 year and 8 month-old boy. Hemosiderin-laden macrophages are demonstrated in smears of material obtained from tracheal aspirates. There were no specific causes for pulmonary hemorrhage....
A Case of Idiopathic Crescentic Glomerulonephritis
Jung Keum Park, Sang Il Goo, Woo Yeong Chung, Chul Ho Kim
Clin Exp Pediatr. 1996;39(1):131-135.   Published online January 15, 1996
We experienced a case of idiopathic crescentic glomerulonephritis in a 10-year-old girl who was admitted to our hospital due to gross hematuria and oliguria for 2 months. The diagnosis was based on the rapidly progressive clinical course to chronic renal failure, positive p-ANCA test and light microscopic findings of diffuse crescents formation in about 80% glomeruli of renal tissue obtained...
A Case of Idiopathic Long QT Syndrome with 2:1 Atrioventricular Block
Kwang In Lee, Chul Ha Kim, In Seok Lim, Dong Keun Lee, Byoung Hoon Yoo
Clin Exp Pediatr. 1995;38(12):1701-1705.   Published online December 15, 1995
The idiopathic long QT syndrome is a very rare disorder in which affected individuals have an unusual electrocardiographic repolarization abnormality (QT prolongation) and a propensity to syncope and fatal ventricular arrhythmia. Since Jervell and Lange-Nielsen first described this syndrome in 1957, progression has been made in the pathophysiology and in the treatment. Sinus bradycardia may be associated with this syndrome sometimes,...
Original Article
Clinical Observations of Transient Idiopathic Hypocalcemia
Jeong Nyun Kim, Mi Jung Park, Duk Hi Kim, Ho Sung Kim
Clin Exp Pediatr. 1995;38(9):1193-1200.   Published online September 15, 1995
Purpose : In concern of diagnosis and treatment of transient idiopathic hypocalcemia, a major cause of infantile, we studied the onset of age, clinical characteristics, laboratory findings, and duration of treatment and recovery of transient idiopathic hypocalcemia. Methods : The author observed 19 infants with transient idiopathic hypocalcemia who had been admitted to Yonsei university hospital due to convulsion for 4...
Doxapram in the Treatment of Idiopathic Apnea of Prematurity Unresponsive to Aminophylline
Jung Hoon Park, Hee Sup Kim, Sang Hee Kim, Gil Hyun Kim, Hak Soo Lee
Clin Exp Pediatr. 1995;38(8):1046-1053.   Published online August 15, 1995
Purpose : Recurrent apnea of prematurity is a very common and troublesome problem despite treatment with aminophylline, and is often associated with a poor developmental outcome. Recently doxapram, a potent respiratory stimulant in adults, has been used to overcome idiopathic apnea of prematurity. This study was to evaluate the efficacy, safety and optimal dosage of doxapram in idiopathic apnea refractory to aminophylline. Methods...
A Comparative Study o fIntavenous Methylprednisolone Dosage for Treatment of Children with Acute Idiopathic Thrombocytopenic Purpura
Eun Ju Shin, Yeong Jae Song, Woo Yeong Chung, Tae Gyu Hwang, Soon Yong Lee
Clin Exp Pediatr. 1995;38(4):513-519.   Published online April 15, 1995
Purpose : It is well known that use of intranenous methylprednisolone(IVMP)for the patients with idiopathic thrombocytopenic purpura(ITP) is not only as effective as use of intravenous gammaglobulin to mincrease platelets quickly, but also the former is less expensive than the latter. As the adequate dosage of IVMP has not been fully elucidated, we have tried to determine it. Methods : The...
Case Report
A Case of Xanthogranulonatous Pyelinephritis with Idiopathic Hypercalciruia in a Child
Young Jun Kim, Hyun Joo Kwak, Keun Haeng Cho, Kee Hwan Yoo, Young Sook Hong, Soon Kyum Kim
Clin Exp Pediatr. 1994;37(12):1778-1783.   Published online December 15, 1994
Xanthogranulomatous pyelonephritis in childhood is a rare chronic pyelonephritis often assodiated with calculi of urinary tract obstruction, with a clinical presentation of renal mass. A 3-year old boy was admitted to Korea University Hospital complaining of intermittent fever and palpable mass at right upper quadrant of the abdomen. The CBC revealed increased ESR and the finding of iron deficientcy anemia....
A Case of Idiopathic Hypereosinophilic Syndrome
Bin Cho, Jin Tack Kim, Joon Sung Lee, Kyoo Hong Cho
Clin Exp Pediatr. 1994;37(7):1020-1027.   Published online July 15, 1994
The idiopathic hypereosinophilic syndrome(HES) represents a heterogenous group of disorder characterized by prolonged eosinophilia of undetectable cause and multiorgan system dysfunction. Bone marrow is the most frequentry involved organ, but the most severe clinicopathologic involvement is heart. The major cause of death in patients with the HES is cardiac dysfunction especially congestive heart failure resulted from endocardial fibrosis and restrictive cardiomyopathy. We...
Original Article
The Effect of Alfacalcidol in the Treatment of Idiopathic Myelofibrosis in Children
Soon Ki Kim, Jeong Hee Kim, Dae Hyun Lim, Jong Woon Choi, Byong Kwan Son, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(3):339-346.   Published online March 15, 1994
Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extramedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposition in IMF using 1, 25-dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F = 1:4) with IMF before and after treatment...
Urinary Vitamin C Loading Test and Therapeutic Effect of Vitamin C in Children with Idiopathic Recurrent Epistaxis
In Soon Park, Woo Yeong Chung, Soon Yong Lee
Clin Exp Pediatr. 1993;36(2):266-272.   Published online February 15, 1993
Recurrent epistaxis is not one of rare symptoms in children, the well-known causes of which are anatomical abnormalities of nasal cavity and systemic bleeding tendency. But, in the majority of cases of recurrent epistasix, it is usually very difficult to find out their underlying causes, so that the treatment is only symptomatic control of nasal bleeding whenever epistaxis occurs, but...
Hypercalciuria Associated with Nephropathy (diagnosis by renal biopsy)
Hyun Ho Shin, Jae Yoon Kim, Chong Woo Bae, Sung Ho Cho, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Moon Ho Yang
Clin Exp Pediatr. 1992;35(11):1509-1513.   Published online November 15, 1992
Idiopathic hypercalciuria is defined as excessive urinary excretion of calcium in normocalcemia without any primary cause. We performed the sono-guided percutaneous renal biopsy for patients of recurrent hematuria, persistent microscopic hematuria, proteinuria and RBC cast to evaluate underlying nephropathy. We could obtained the following results 1) The age at the renal biopsy ranged from 3 years to 14 years. Sex ratio is 1.9:1...
Case Report
Two Cases of Idiopathic Pulmonary Fibrosis
Young Gyun Oh, Seoung Hwan Kim, Mi Reong Kim, Byung Kiu Park, Hee-Shang Youn, Myung Kul Yum
Clin Exp Pediatr. 1992;35(1):122-128.   Published online January 15, 1992
Idiopathic pulmonary fibrosis is a heterogeneous group of disorder which predominantly affects the lung parenchyma and spares the airway. We report two cases of idiopathic pulmonary fibrosis in a 2 year 11 month-old female and a 1 year 1 month-old male patients who were treated with steroid. These patients presented with dyspnea and showed fine crepitant rales in both lung...
Original Article
A case of idiopathic precocious puberty treated with a luteinizing hormone relaeasing hormone analog.
Keun Hee Chung, Yoo Mi Kim, Mi Won Kim, Soon Ki Kim, Moon Soo Park, Jin Keun Chang
Clin Exp Pediatr. 1991;34(8):1132-1138.   Published online August 31, 1991
We experienced a 4 year girl with idiopathic precocious puberty treated with a long acting LHRH analog (Buserelin). As an indction therapy she received LHRH analog for 6 months in subcutaneous route. After then she was maintained by intranasal therapy for 6 months. One month after the induction therapy began, we observed prepunbertal pattern of LHRH stimulation test and significant suppression of 17B-estradiol level....
A case of Idiopathic Crescentic Glomerulonephritis.
Mi Kyung Kim, Hyun Joo Choi, Seung Joo Lee, Ok Kyung Kim
Clin Exp Pediatr. 1989;32(10):1435-1441.   Published online October 31, 1989
Idiopathic crescentic glomerulonephritis is a very rare disease especially in children with poor prognosis. We experienced a case of idiopathic crescentic glomerulonephritis in a 4-year-old male patient who presented initially with a nephrotic syndrome and progressed to a rapidly progressive glomerulonephritis. We review literatures briefly.
Idiopathic Hypercalciuria in Children.
Kyung Ha Ryu, Seung Joo Lee, Keun Lee, Jae Sun Jung
Clin Exp Pediatr. 1989;32(6):809-815.   Published online June 30, 1989
Idiopathic hypercalciuria is defined as increased urinary excretion of calcium in normocalcemia without primary cause. It is associated with urinary symptoms, such as hematuria but it occurs without any symptoms too. If left untreated, it may cause kidney stone, dimineralization of bone, or other problem. The incidence of idiopathic hypercalciuria was 3.9% in asymptomatic group compared to 5% in unselected populations in this study....
Two Cases of Idiopathic pulmonary Hemosiderosis.
Sung Ky You, Ki Soo Kim, Young Jee Kim, Young Yull Koh, Yeon Lim Suh, Je Geun Chi
Clin Exp Pediatr. 1988;31(9):1209-1216.   Published online September 30, 1988
Idiopathic pulmonary hemosiderosis is an uncommon disease of undetermined cause that is char- acterized by periodic episodes of cough, hemoptysis, widespread pulmonary infiltrates and hypo- chromic anemia. Two cases of idiopathic pulmonary hemosiderosis were diagnosed after open lung biopsy. It revealed hemosiderin and hemosiderin-laden macrophage. There were no specific causes for pulmo- nary hemorrhage. We report 2 cases of idiopathic pulmonary hemosiderosis with brief review...
Two Cases of Idiopathic Hypercalciuria in Children.
Joon Cho, Hye Lyung Baik, Hong Jong Joo, Jin Keun Chang, Moon Soo Park, Sung Woo Shin
Clin Exp Pediatr. 1988;31(5):635-640.   Published online May 31, 1988
We herein experienced two cases of idiopathic hypercalciuria in a 4 year old boy and 8 year old boy who had asymptomatic gross hematuria. Diagnosis was made by a urinary calcium excretion of more than 4 mg per kilogram of body weight per 24 hours and by a urinary calcium-creatinine ratio of more than 0.21, under situation that specific etiology of hypercalciuria was not...
A Case of Idiopathic Unilateral Hyperlucent Lung Associated with Low Serum IgA.
D H Chee, W S Shim, M I Lee, D H Ahn, K C Sohn, J H Yoon
Clin Exp Pediatr. 1988;31(4):526-531.   Published online April 30, 1988
Swyer-James syndrome is a radiological entity that consists primarily of an abnormal radiolucency of one lung or lobe due to obliterative bronchiolitis with air entrapment. We report a case of idiopathic unilateral hyperlucent lung which was confirmed by chest roentgenography, bronchogra- phy and pulmonary arteriography in a patient whose serum IgA was significantly lowered.
The Role of Anitiplatelet Antibody and the Therapeutic Effect of High-Dose I.V. gamma-globulin in Childhood Idiopathic Thrombocytopenic Purpura.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1988;31(2):212-219.   Published online February 28, 1988
Among 48 children with I.T.P (26 acute, 10 chronic and 12 undetermined), the antiplatelet antibody test (APA) was qualitatively studied by indirect immunofluorescent method in 34 patients of which only 25 patients (18 acute and 7 chronic) were able to follow-up. The overall positivity of APA was 36% and there was no relationship with disease chronicity. Intravenous r-globulin was given at a dose of...
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
Clinical Status of Apnea in Prematurity.
Soon Hee Kim, Chang Soo Ra, Keun Lee
Clin Exp Pediatr. 1986;29(7):758-764.   Published online July 31, 1986
Apnea is defined as cessation of respiration for longer than 10 〜20sec with or without bradycardia or cyanosis. It is more frequent in premature than full-term infants. The medical records of 96 premature infants of gestational age below 36 weeks who were hospitalized at Nursery of Ewha University Hospital during the period from July, 1982 to July, 1984, were analyzed....
Clinical Study of Idiopathic Thrombocytopenic Purpura in Children.
Kwang Nam Kim, Sang Hee Cho, Je Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1985;28(3):251-257.   Published online March 31, 1985
The authors studied 26 cases with idiopathic thrombocytopenic purpura who were admitted to Department of Pediatrics Hanyang University Hospital. The results were as follows: 1)The peak incidence of age was 5 to 7 years old. Male to female ratio was 2.7 : 1 which showed: slight male preponderance. 2)lThe most prevalent seasons were spring and summer. In both seasons, the...
Case Report
A case of Idiopathic pulmonary hemosideroisis.
Yeong Hee Kim, Jeong Hee Lee, Seung Joo Lee, Keun Lee, Ok Kyung Kim, Doo Yeon Lee
Clin Exp Pediatr. 1985;28(2):182-186.   Published online February 28, 1985
Idiopathic Pulmonary Hemosiderosis is a rare disease characterized by recurrent attacks of hemoptysis, iron deficiency anemia and pulmonary infiltration on chest X-ray. We experienced a case of Idiopathic Pulmonary Hemosiderosis in a 3 year-old boy with recurrent attacks of dyspnea, pallor and chest infiltration on X-ray, without underlying pulmonary disease. Diagnosis was established by hemosiderin and hemosiderin-laden macrophage on lung...
Original Article
Idiopathic Membranoproliferative Glomerulonephritis in Children.
Hae Il Cheong, Hee Shang Youn, Whan Jong Lee, Yong Choi, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1985;28(1):45-57.   Published online January 31, 1985
Among total 452 children with percutaneous kidney needle biopsy due to renal disease in the Department of Pediatric, Seoul National University Hospital, from Jan. 75 to Nov.84, 20(4.4%) were confirmed as embranoproliferative glomerulonephritis(MPGN) histopathologically. And 4 out of these 20 were excluded from this report because of association of systemic disease. A review of clinical and pathological findings of the...
Case Report
Three Cases of Idiopathic Hypertrophic Subaortic Stenosis.
Sei Weon Yang, Dong Gyoon Kim, Jong Jin Seo, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1984;27(5):493-500.   Published online May 31, 1984
Idiopathic Hypertrophic Subaortic Stenosis is a primary disease of cardiac muscle that is probably congenital, is often genetically transmitted, and is characterized by asymmetric septal hypertrophy, systolic anterior motion of anterior mitral valve and disorganization of cardiac muscle cells. The authors experienced 3 cases of Idiopathic Hypertrophic Subaortic Stenosis which were confirmed by echocardiography, cardiac catheterization and angiocardiography. The literatures...
Two Cases of Rotor Syndrome in Brothers.
Sonn Il Kwon, Kum Le Ko, Jong Hun Park, Young Soo Lim, Dong Heuck Kum
Clin Exp Pediatr. 1983;26(9):934-938.   Published online September 30, 1983
Two cases of Rotor syndrome were observed clinically. Both cases were observed as follows; 1. Both cases were observed in a same family; They were brothers. 2. Jaundice was appsirel fro.n aboat sscoai year of life without any clinical disturbance. 3. Oral cholangiography and Ultra sonogram on abdomsn showed normal Findings and functions except slight enlargement of liver. 4. Direct...
A Case of Myelofibrosis.
Ho Seong Yoo, Jin Heon Kim, Keun Chul Myung, Chang Soo Ra
Clin Exp Pediatr. 1983;26(8):829-834.   Published online August 31, 1983
Myelofibrosis is characterized by fibrosis of bone marrow, leukoerythrobla stotic anemia and extramedullary hematopoesis with varying degree of hepatosplenomegaly. Idiopathic myelofibrosis is primarily a disease of the adult and is rare in the pediatric age group. We experienced a case of idiopathic myelofibrosis in a 2 year 5 month old male who showed severe anemia with abnormal forms of red blood cell (teardrops, ovalocytes),...