The importance of establishing authentic normal platelet count, mean platelet volume and platelet distribution width in the newborn has been emphasized, but they have not been firmly established. We have presented values for platelet count, mean platelet volume and platelet distribution width in the venous blood of term, small for gestational age and premature neonates at postnatal day 1 and 7. The results were... |
Transverse myelopathy is characterized by a sudden onset of motor weakness and sensory loss on the distribution under the affected spinal cord level. And slso, autonomic nerve functions may be disturbed at the same time. The etiology is still unknown. But it is thought that numerous conditions and diseases are associat- ed with it. We experienced 3 cases of transverse myelopathy preceded by Korean hemorrhagic... |
Toxic epidermal necrolysis is a bullous erythematous disease characterized by scalding appearance of the skin. And , it is divided into drug induced, miscellaneous, idiopathic group by the etiology. We experienced a cases of Phenytoin induced toxic epidermal necrolysis. So, we presented the case and reviewed the literatures about it. |
Asphyxiating thoracic dystrophy, a rare form of bony dysplasia, is characterized by extreme constriction of thorax, short limbed dwarfism, abnormalities of pelvic bone in neonatal period, and progressive interstitial nephritis in childhood. The incidence of this syndrome has been estimated at 1 per 100,000 to 130,000 live births and more than 100 patients have been reported worldwide. Infants with asphyxiating thoracic dystrophy usually have... |
Esophageal duplication, a term used synonymously with enteric cyst, foregut cyst, gastroenteric cyst, enteric duplication, and etc, is a rare developmental anomaly which occures during differentia- tion of the larynx, trachea, and bronchi from the primitive foregut. They may cause dysphagia, regurgitation, pneumonia, hemoptysis, and occasionally produce alarming airway obstruction. We experienced a case with chief complaints of pale appearance and swallowing difficulty in... |
A rare form of congenital cystic lung disease, characterized by the presence of one or usually multiple interconnecting cyst, is called congenital cystic adenomatoid malformation of the lung. This disease almost invariably presents either in live premature or stillborn infants, and death in those infants bom alive usually occurs within a few hours of birth. Infants with congenital cystic adenomatoid malformation usually have tachypnea,... |
Three-step guided compliance training and movement suppression time-out technique were used to treat desruptive, self-injurious, and aggressive behaviors in an 8-years old tuberous sclerosis with severe mental retardation. In compliance training, the child’s compliance behavior to verval and/or gestural demand was reinforced with edible and/or social reinforcers and the noncomplied demand was forcefully carried out through physical prompting. Movement suppression time-out was enforced whenever any... |
We measured the glucose diappearance rate(Kt) in 24 normal neonates and in 19 ill neonates by intravenous glucose tolerance test. The results were as follows: 1) The glucose disappearance rate of 2-day-old normal neonates was 1.59±0.8%/min. 2) The glucose disappearance rate of ill neonates who had negative culture studies was 2.08±l. 4%/min. 3) There was no significant difference in glucose disappearance rate between normal neonates and ill neonates who had... |
Dapsone syndrome is a rare hypersensitivity reaction to Dapsone. The reaction included fever, malaise, dermatitis jaundice with hepatic dysfunction, lymphadenopathy, and hemolytic anemia. We have experienced a case of Dapsone syndrome in a 10 years old male. This patients had taken D.D.S. with 50 mg per day for 1 month to treat an unknown skin disease. After then, above mentioned symptoms and signs were... |
Comparison of urinary specific gravity by refractometer and osmolality in 238 neonates demonstrated as followings; 1) The regression line is represented by the equation: Y = 107+14.2 (X-1000) while Y = osmolality in mosm/kg X = Specific gravity by refractometer r=0.8545 2) Osmolality is the only accurate measure of urine concentration in newborn infants. If the specific gravity by refractometer is used to screen for urine concentration, an elevated level... |
Serum glucose changes by constant infusion of glucose at the rate of 8 mg/kg/min were studied in 20 neonates. Serum glucose level elevated from 41 ±8 mg/dl to 80 ±31 mg/dl within 10 minutes of infusion. In some cases hyperglycemia above 150 mg/dl was observed from 40 minutes of infusion. Constant glucose infusion was found to be useful for elevation of glucose level... |
Alpha-fetoprotein(aFP) levels were studied in 20 neonatally hyperbilirubinemic children and 20 controls matched for gestational age. The mean aFP value of cord blood (119+58.2산g/ml) with hyperbilirubinemic children was significantly greater than that(79.6±40.8/zg/ml) for the control infants(P<0.001). At the age of 3 and 5 days the mean serum aFP in hyperbilirubinemic children were higher compared with the control group, the difference... |
To determine the proper age of the measles vaccination, we must know the time when the passively transferred measles antibody from mother disappeared. Because it can be a major factor for vaccine failure to take the measles vaccine to the children who still have the passive immunity. We measured the degree of immunity of 50 children with the age between... |
We experienced a case of eosinophilic granuloma with multiple lesions on skull, ribs, vertebrae, tibia and pelvic bone. In addition, recurent bacterial meningitis was associated with CSF rhinorrhea probably due to osteolytic lesion of eosinophilic granuloma in the same patient. A brief review of literature was made. |
We experienced a case of preleukemia of 8-year-old male child, whose initial diagnosis was aplastic anemia, but 2 months later, acute lymphocytic leukemia was developed. So, we concluded that the initial state presenting as aplastic anemia had been prelekemia. Literatures were briefly reviewed. |
We experienced a case of Pierre Robin syndrome in newborn consisted of micrognathia, cleft palate and glossoptosis. It may accompany with cardiac malformations and ocular anormalies, which were not found in this baby. Brief review of literature was made. |
Neonatal jaundice is probably the most frequently encountered diagnostic and therapeutic problem in the newborn, but its accurate assessment still requires a measurement of the serum bilirubin concentration. To date, repetitive and continuing blood sampling has been the only acceptable methodology available for monitoring the jaundiced newborn infant. This technique serves as a source of discomfort and of serious infection(Lilien... |
Infantile polycystic kidney is uncommon disease and rare in children and is used to refer to a group of heritable conditions that occur predominantly in childhood and is transmitted by autosomal recessive inheritance. By developmental abnormality, multiple cysts are produced from enlargement or giantism of the collecting tubules in association with cellular hyperplasia. Kidneys are grossly enlarged and have a diffusely... |
200 cases of aseptic meningitis were clinically observed for 171/2 years from 1966, Jan. to 1983, Jun. Eitologic classification showed that there were 165 cases (82.5%) of unknown etiology because virus was not identified, 30 cases (15.0%) of mumps, and 5 cases (2.5%) of Kawasaki disease. The most frequent age group was early childhood (81 cases, 40.5%) and more frequently in males (139... |
Neuroblastoma is the commonest malignant tumor identified during the neonatal period and the majority of neuroblastomas are felt to be congenital in origin. Neuroblastoma is a tumor of particular interest because it is known to arise from cells of the neural crest which possess the potential for maturation of spotaneous regression. This report present the clinical, radiographic and autopsy findings of... |
We experienced a case of human fascioliasis in a 4-y-old male child who had been suffered from abdominal pain, pallor and intermittent generalized edema for about 21 months. Diagnosis was established by eggs of Fasciola species in stool and by double diffusion analysis. After treatment with bithionol, the symptoms were disappeared rapidly and the eggs also disappeared. A brief review... |
Aplastic Anemia following Hepatitis is an uncommon disease and it has a poor prognosis. Recently the authors experienced two cases of aplastic anemia following hepatitis in a 13 year old girl and a 14 year old boy. The thirteen year old girl was admitted following 2 months of Jaundice and 1 day df epistaxis. . At admission, pancytopenia developed and her... |
We experienced, a case of holoprosencephaly with no extracranial annormalities, normal chromosme count and karyotype. The diagnosis was confirmed by brain C-T scan, which was compatible to semilobar type of holoprosencephaly. The patient is living now at 2 years old. Review of the references concerning holoprosencephaly was made briefly. |
Hereditary anhidrotic ectodermal dysplasia is a rare hereditary condition in which certain structures derived from the ectoderm are undeveloped or underdeveloped, although, on a rarity, mesodermal or endodermal derivatives may be associated. Recently, we have experienced a case of anhidrotic ectodermal dysplasia in 4 years old male. He had abscence of sweating, hypotrichosis and anodontia, which was characteristic features of this disorder. We established... |
Thonatophoric dwarfism is a severe form of micromelic dwardism which is in variably fatal in the neonatal period. We reported one case of thanatophoric dwarfism with review of literature. The diagnosis was confirmed by clinical features, radiological and histological find ings. |
A clinical study of bacterial meningitis in. 126 cases occurred in the age under 15 year admitted to the department of Pediatrics at Wonju Christsan Hospital, Yonsei University was made from Jan. 1, 1972 to Dec. 31, 1981. The results are as follows. 1) Among the 126 cases. 83 cases (65.9%) were male and 43 cases (34.1%) were female The sex... |
Leukemia, the most common malignant disease in pediatric field, is one of the most interesting targets of modern medical research. So we reviewed the bone changes in 51 patients of leukemia admitted to the Dept, of Pediatrics Jeonbug National University Hospital for 5 years from Jan. 1st 1977 to Dec. 31st 1981. The results were as follow. The male patient was... |
A Clinical Study was made on. 542 low birth weight infants, admitted to the department of pediatrics, Wonju Christian Hospital during 6 years from 1975 to 1980. The results were as follows: 1) Incidence of low birth weight infants was 12.8% without sexual and seasonal predo- migance, of which small for gestational age infants were about 50%. 2) Low birth weight infants were most prevalent among mothers... |
This experiment was carried out to investigate the effects of anticancer drugs on the phagocytic function of reticuloendothelial system. The phagocytic activity was assessed by- means of carbon clearance method, after intravenous injection of vincristine(5 pg or 25 y^g/lOO gm of body weight) and adriamycin (70 pg or 350 ^g/100 gm of body weight) through one, two, and three times at the interval of... |
Clinical and Bacteriological studies were carried out on 57 cases of infants and children with shigellosis who were cared from January, 1976 to December, 1980 in our hospital. The results were as follows: 1. The age distribution revealed the range between 6 months and 5 years(85% of all) with sex ratio of 30(53%) of male and 27(47%) of female, 1.1:1.... |
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