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Original Article
Endocrinology
Lipid accumulation product is a predictor of nonalcoholic fatty liver disease in childhood obesity
Bahar Özcabı, Salih Demirhan, Mesut Akyol, Hatice Öztürkmen Akay, Ayla Güven
Clin Exp Pediatr. 2019;62(12):450-455.   Published online October 28, 2019
Background: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults.
Purpose: Here we evaluated the ability of LAP to predict NAFLD in obese children. Methods: Eighty obese children (38 girls; age 6–18 years) were included. Anthropometric measurements and biochemical values were obtained from the patients’ medical records. LAP was calculated as [waist...
Association of apolipoprotein E polymorphisms with serum lipid profiles in obese adolescent
Jung Min Yoon, Jae Woo Lim, Eun Jung Cheon, Kyoung Og Ko
Clin Exp Pediatr. 2008;51(1):42-46.   Published online January 15, 2008
Purpose : Apolipoprotein E (Apo E) plays a major role in lipoprotein metabolism and lipid transport. Many investigators have described that Apo E polymorphisms is one of the most important genetic determinants for cardiovascular disease. The purpose of this study was to evaluate the association between Apo E polymorphisms and serum lipid profiles in obese adolescent. Methods : We measured...
Changes of Lipid and Lipoprotein Compositions in Kawasaki Disease and its Impact on Cardiac Complications
Sin Weon Yun, Ho Seok Lee, Dong Woon Kim, Kang Won Rhee, Young Soo Jung
Clin Exp Pediatr. 2005;48(12):1370-1377.   Published online December 15, 2005
Purpose : Delineation of serum lipid and lipoprotein values in children after Kawasaki disease(KD) is important because of the predilection of this disease for the coronary arteries. Methods : The KD group was composed of 51 patients who were hospitalized from Jan. 2002 to Dec. 2003. Control was 25 patients with non-KD febrile illness. The levels of total lipid, phospholipid,...
Changes of Body Weight and Lipid Profiles According to Apolipoprotein E Polymorphism in Children with Antiepileptics
Seung Hee Jang, Eun Kyoung Choi, So Hee Eun, Sun Jun Kim
Clin Exp Pediatr. 2002;45(1):88-94.   Published online January 15, 2002
Purpose : Weight changes, especially weight gain, is a side effect of antiepileptics(especially valproate and carbamazepine). This may be sufficiently severe to cause noncompliance or to require the withdrawal of effective treatment. Unfortunately, the exact mechanism of weight change is not illustrated. Several reports and our experiment suggested that weight gain highly correlated with a familial tendency of obesity. The genetic makeup is a...
Apolipoprotein E Polymorphism and Plasma Lipid Levels in Obese Children
Myoung Hee Han, Sun Jun Kim
Clin Exp Pediatr. 2000;43(5):679-685.   Published online May 15, 2000
Purpose : The increased prevalence of dyslipoproteinemia in obese children probably contributes to the high risk of cardiovascular disease associated with being overweight. The genetic makeup is possible one of the factors that influence the impact of obesity on lipid metabolism. A relation between apolipoprotein E(Apo E) polymorphism and lipid metabolism has been convincingly demonstrated in large population. The purpose...
Complications, Apolipoproteins and Lipoprotein(a) in Severely Obese Children in Incheon, 1996
Yon Ho Choe, Yong Hoon Jun, Soon Ki Kim, Seung Kyu Han, Byong Kwan Son, Jong Weon Choi, Soo Hwan Pai
Clin Exp Pediatr. 1997;40(10):1386-1393.   Published online October 15, 1997
Purpose : This study was designed to evaluate the incidence of complication in severely obese children and to determine whether the difference of Lp(a) between severely obese children and normal control group exists. Methods : Body weight, height and obesity index were measured in 5885(M:F= 3089:2796) elementary school children. Eight eight(M:F=63:25) were selected as severely obese children. Of the 88 children, 74 agreed to venous...
Lipid Profile and Its Association with Coronary Aneurysm in Kawasaki Disease
Ju Sik Choi, Suk Min Choi, Kyu Hyung Lee
Clin Exp Pediatr. 1997;40(6):835-840.   Published online June 15, 1997
Purpose : The value of serum lipid in children after recovery of Kawasaki disease may be important because of the predilection of this disease for the coronary artery. Methods : We measured serum high density lipoprotein(HDL)-cholesterol, total cholesterol, triglycerides in 22 patients (mean age 38months, range 6 to 93 months) with Kawasaki disease during 10 days or less after onset and 2 months later...
Plasma Lipid Alteration in Leukemia and Solid Tumor
Eun Sik Kang, Myoung Soon Song, Hea Jin Cheoh, Kyu Chul Choeh
Clin Exp Pediatr. 1995;38(4):529-536.   Published online April 15, 1995
Purpose : A sensitive, specific blood test to detect cancer would be of great value but the search for such a test has been fruitless so far. In actual practice, there is often a considerable interval between the point at which a tumor could have been detected and the point at which it produces symptoms as a result of tumor...
Case Report
A Case of Type V Hyperlipoproteinemia
Yo Ahn Rho, Jong Kwang Lee, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1994;37(12):1752-1756.   Published online December 15, 1994
The hyperlipoproteinemias are the disturbance of lipid transport resulted from accelerated synthesis or retarded degradation of lipoproteins that transport cholesterol and trigycerides through plasma. These diseases are classified as type I, type IIa, type IIb, type III, type IV, type V, and hyper-α-triglyceride levels due to increases in both VLDL and chylomicrons and lipoprotein electrophoresis shows increases pre-β, β, and...
Original Article
A Study on Evolution of Lipoportein(a) in Newborns
Keun Haeng Cho, Young Sook Hong, Soo Won Lee, Soon Kyum Kim, Young Chang Tockgo, Han Kyeom Kim
Clin Exp Pediatr. 1994;37(8):1078-1091.   Published online August 15, 1994
Lipoprotein(a) [Lp(a)] is considered an additional, independent and largely genetically determined risk factor for the development of premature coronary heart disease. Furthermore abnormal plasma lipoprotein patterns have been associated with increased risk for developing coronary heart disease. Among these lipoproteins, an increased concentration of serum Apo B and decreased level of Apo A are considered as major risk factors, together...
Lipoproteinelectropheresis pattern in Nephrotic Syndrome.
Soon Don Hong, Byung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1988;31(9):1163-1170.   Published online September 30, 1988
This study was undertaken to eluidate lipoprotein patterns in patients with childhood nephrotic syndrome by response to initial steroid therapy, serum albumin level in MCNS and other histologic classifications. The result were summerized as follows. 1) There were 19 cases (52.8%) of abnormal lipoprotein patterns by Fredrickson classifications, type Ila were 6 cases (16.7%), type lib were 1 cases (2.8%) and type IV were 12 cases...
A Study on Serum Lipids and Lipoproteins in Acute Viral Hepatitis in Children.
Kyu Hyoung Han, Chang Soo Ra
Clin Exp Pediatr. 1985;28(7):642-652.   Published online July 31, 1985
Most of the lipids in serum are transported in the from of lipoproteins. A major portion of these lipoproteins is formed in the liver. The determination of serum lipoprotein patterns is a better index of liver abnormalities than determination of lipids alone. The authors determined serum lipid concentration and the patterns of serum lipoproteins in 40 cases of acute viral...
Hyperlipidemia and Hyperlipoproteinemia in Focal Segmental Glomerulosclerosis Nephrotic Syndrome.
Heui Jeen Kim, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(10):967-977.   Published online October 31, 1983
Sera obtained from 23 hospitalized patients with focal segmental glomerulosclerosis nephrotic syndrome which is confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine protein, creatinine clearance, HDL-cholesterol. In 19 of the patients lipoproteins were analyzed. the following results were obtained. 1) Serum phospholipid (PL) was increased whenever serum total cholesterol (TC) was increased but to a lesser degree. The ratio of TC/PL...
Study of Serum Lipids and Lipoprotein in Patients with Nephrotic Syndrome.
Eui Soo Park, Jeh Hoon Shin, Woo Gill Lee, Chong Moo Park
Clin Exp Pediatr. 1983;26(4):349-357.   Published online April 30, 1983
The nephrotic syndrome is characterized by generalized edema, hypoproteinemia (serum albumin; below 2.5 gm/dl), hyperlipidemia (serum cholesterol; above 220 mg/dl), massive proteinuria (2.0 gm/M2/24 hrs or more). For causes of hyperlipidemia, decreased plasma lipoprotein lipase activity and decreased serum albumin have been postulated as contributing factors. So the serum lipids and lipoproteins were studied in 24 patients with nephrotic syndrome...
Lipoprotein Profiles in Minimal Change Nephrotic Syndrome.
Yong Choi, Heui Jeen Kim, Hae Il Cheong, Jeong Kee Seo, Kwang Wook Ko
Clin Exp Pediatr. 1983;26(3):237-246.   Published online March 31, 1983
Data obtained from 59 hospitalized patients with minimal change nephrotic syndrome which was confirmed by kidney biopsy, were analyzed for serum albumin, serum lipids, 24hr urine protein, creatinine clearanee, HDL-eholesterol. In 38 of the patients, lipoproteins were analyzed. The following results were obained 1. Serum phospolipid (PL) was increased whenever serum total cholesterol (TC) was increased but to a lesser degree. The ratio of TC/PL were...
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