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Case Report
A Case of Neonatal Tetanus Cured with Neuromuscular Blocking Agent and Ventilatory Support
Hyeon Joo Lee, Ji Young Jeong, Sa Jun Jung, Yong Mook Choi, Chong Woo Bae
Clin Exp Pediatr. 2003;46(2):192-194.   Published online February 15, 2003
A neonate born at 38 gestational weeks was admitted due to generalized tonic-clonic seizure and cyanosis. The neonate was born six days previously at home through normal delivery and the umbilical cord was cut using scissors sterilized in boiling water. The neonate weighed 3,180 g at admission. Physical examination revealed cyanosis, opisthotonus, trismus and reactive muscle spasms. Laboratory exam, brain...
Original Article
The Treatment of Croup with Nebulized Budesonide and Intramuscular Dexamethasone
Jung Woo Lee, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung, Yong Mook Choi
Clin Exp Pediatr. 1998;41(3):331-337.   Published online March 15, 1998
Purpose : Steroids have anti-inflammatory effects which reduces inflammation and edema of the tissue. Thus, corticosteroids have been used for treatment of croup. The aim this study is to compare and assess the effects of intramuscularly injected dexamethasone and nebulized budesonide in treatment of moderate or severe croup. Methods : Between July 1995 to June 1996, we have assessed 44 inpatients...
Analysis of Urinary Mass Screening for Elemantary, Junior and High School Children Over a 8-year Period in Seoul
Chong Guk Lee, Dong Whan Lee, Sae Won Yang, Sung Ho Cha, Chang Ho Hong, Yong Mook Choi, Hyun Soon Lee, Sung Jae Seo
Clin Exp Pediatr. 1997;40(10):1347-1359.   Published online October 15, 1997
Purpose : The urinary mass screening program for the detection of proteinuria had been performed for a school age population in the city of Seoul since 1981. However, systematic evaluation for this program had never been done. We, therefore, designed a systematic evaluation in corporation with the Seoul School Health Center for students with proteinuria identified in the mass screening to determine the prevalence...
A Clinical Study on Infantile Spasms with Prednisolone Therapy
Hye Sun Yoon, Young Hoon Choi, Ho Suk Lee, Yong Mook Choi, Sa Jun Chung
Clin Exp Pediatr. 1996;39(4):522-529.   Published online April 15, 1996
Purpose : Infantile spasms are considered malignant epilepsy of infancy. Primary objectives of treatment are complete control of seizure attack and prevention of further brain damage. The aim of this study is to assess prednisolone(PDL) efficacy in infantile spasms. Methods : From June 1985 to July 1994, 20 children with infantile spasms who were diagnosed at Kyung Hee University Hospital and were...
Upper Limit of Normal Value for Antistreptolysin O Titer of Healthy Children in Seoul
Sung Ho Cha, Yong Mook Choi, Sei Won Yang, Dong Hwan Lee, Chong Guk Lee, Chang Ho Hong
Clin Exp Pediatr. 1995;38(8):1061-1068.   Published online August 15, 1995
Purpose : We have found somewhat high titer of antistreptolysin O (ASO) accidentally when we had delineated normal carrier rate of beta hemolytic streptococci in rural area of Kangwon Province in 1991(1). We would like to know upper limit of normal value of ASO and re-valuated results which might be changed with different geographic areas, age, and prevalent rate...
Accuracy of anorectal manometry in the diagnosis of congenital megacolon.
Jong Yul Jeon, Byeong Gie Yeo, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Woon Chang
Clin Exp Pediatr. 1991;34(5):614-620.   Published online May 31, 1991
Thirty-seven patients with clinical impression of congenital megacolon were studied with anorectal manometry for the evaluation of its diagnostic accuracy. Including 12 neonates, their age ranged form 3 days to 8 years and barium enema was performed to all of them except one. The results of rectosphincteric reflex (RSR) of anorectal manometry was compared with the final diagnosis, which was obtained by clinical course,...
A case of thrombasthenia.
Yong Bae Suh, Eun Kyoung Sohn, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1991;34(2):287-291.   Published online February 28, 1991
Glanzmann’s thrombasthenia is a congenital disorder of platelet function with missing or abnormal platelet plasma membrane glycoprotein Ilb/IIIa which function as receptors for fibrinogen and other high-molecular-weight adhesive proteins which are important for platelet aggregation. We have experienced a case of thrombasthenia in a 12 month old male whose chief complaints were easy bruising and frequent epistaxis. The beeding time was prolonged in the...
A clinical study on the idiopathic respiratory distress syndrome of the newborn: comparison of radiographic and clinical findings.
Byoung Yul Lim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee
Clin Exp Pediatr. 1991;34(1):16-23.   Published online January 31, 1991
Idiopathic respiratory distress syndrome (IRDS) of the newborn remains an important and signifi- cant cause of morbidity and mortality despite of improvement in neonatal care. The clinical and radiologic features observed are the results of surfactant deficiency combined with a highly compliant chest wall. We have been applied the clinical and radiologic features in the diagnosis of IRDS. In 1974, Bomsel et al reported the...
A Case of (21q 21q) Translocation Down Syndrome Inherited from a t(21q 21q) Balanced Carrier Mother.
Byeong Gie Yeo, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Bo Hoon Oh
Clin Exp Pediatr. 1990;33(7):1004-1008.   Published online July 31, 1990
Vast majority of t(21q 21q) Down syndrome occur de novo and familial cases are extremely rare. In familial translocation Down syndrome, One of the parent show 45 chromosomes. In general, the carrier parent carrying (21q 21q) translocation is phenotypically normal because significant amount of genetic material has not been lost in the translocation process. Homologous Robertsonian translocation can be produced either by abnormal gametogenesis...
A Comparative Study of Therapeutic Effect of Intravenous Gammaglobulin plus Aspirin Versus Aspirin Alone in Kawasaki Syndrome.
Boung Yul Leem, Chong Sung Chung, Sung Ho Cha, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1408-1415.   Published online October 31, 1989
We compared the efficacy of intravenous gamma globulin plus aspirin with that of aspirin alone in reducing the frequency of coronary artery abnormahties and changes of clinical coures in children with acute kawasaki syndrome in the children of 44 cases who were admitted in K.H.U.H from Mar. 1986 to Fab. 1988. Group A: High dose aspirin (60〜90 mg/kg/D) during febrile stage and then switched...
The Clinical study of Acute Poisoning in Children.
Ji Ho Song, Sang Young Chung, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1331-1336.   Published online October 31, 1989
A clinical study was performed on 145 cases of acute poisoning who were admitted in pediatric department of Kyung Hee University Hospital during the past 15 years from Jan. 1973 to Dec. 1987. The results are as follows; 1) There was no significant annual differences in frequency of poisoning, and the peak incindence in a year was in April and July (12.4%). 2) The sex ratio of...
A Clinical Study of Kawasaki Disease Complicating Coronary Aneurysm.
Chong Sung Chung, Byung Yul Lim, Sung Ho Cha, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1240-1247.   Published online September 30, 1989
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children younger than age 5 years. Coronary aneurysms are most serious complication in Kawasai diseas and are developed in 15〜20% of patients. We studied 15 children Kawaski disease complicating coronary aneurysms, who were admitted to the Kyung Hee University Hospital during the period of January 1984 through January...
A Study of Milk β-Glucuronidase Activity in Breast Milk Associating with Neonatal Jaundice.
Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1202-1209.   Published online September 30, 1989
Since the 1960s, several reports have been presented to explain how the ingestion of human milk is related to neonatal jaundice. Recently, the jaundiced neonates whose mother’s milk contain sub- stances (eg, pregnane 3a, 20β-diol, lipoprotein lipase, free fatty acid, β-glucuronidase etc) facilitating the reabsorption of unconjugated bilirubin in the neonatal intestine through the enhancement of the enterohepatic circulation, were called the breast milk...
Change of NK Cell and LAK Cell Activity of Cancer Patients in Postchemotherapy Period.
Chong Sung Chung, Kyuchul Choeh, Yong Mook Choi
Clin Exp Pediatr. 1989;32(7):933-942.   Published online July 31, 1989
This study was undertaken to evaluate the Natueral-Killer (NK) cell and Lymphokine-Activated-Killer (LAK) cell activity of cancer patients for the prupose of understanding of spontaneous cell-mediated cytotoxicity (SCMC) in cancer patients and understanding of interrelationship between NK cell and LAK cell. Total 9 cases of malignant tumor (7 cases: Acute leukemia, 2 cases: malignant lymphoma) below 15 years of age, who were on remission...
Acid-Base and Electrolyte Change Before and After Exchange Transfusion with ACD-B Blood in Hyperbilirubinemia of Newborn.
Ki Hong Park, Chong Woo Bae, Yong Mook Choi, Chang Ill Ahn, Jung Kook Lee
Clin Exp Pediatr. 1989;32(3):311-320.   Published online March 31, 1989
Exchange transfusion is being used widely to correct anemia and control existing hyperbilirubinemia for the prevention of kernicterus in newborn. But the blood used for exchange transfusion is stored blood containing anticoagulants and other substances. So many metabolic changes can be developed after exchange transfusion. This study was undertaken to evaluate the acid-base and electrolyte change after exchange transfusion using the ACD-B blood. In...
Studies in Anemia of Infancy and Children During Hospitalization.
Tae Kyu Hame, Jeong Sam Jeon, Kyu Chul Choi, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(10):1338-1345.   Published online October 31, 1988
This investigational work-ups were studied in 303 cases of anemia including 45 cases of severe degree anemia retrospectively among total inpatients of 3387 in the Department of Pediatrics, Kyung Hee University Hospital for recent two years form Mar. 1985 to Feb. 1987. The results were obtained as follows; 1) The orerall incidence of anemia among total inpatients(3387) was 8.9%(303 case). The incidence of severe anemia was...
Diagnostic Value of the Lung Perfusion Scan in Foreign body Aspiration.
Ki Hong Park, Chong Woo Bae, Byoung Soo Cho, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee, Chang Il Cha
Clin Exp Pediatr. 1988;31(10):1301-1307.   Published online October 31, 1988
Lung perfusion scan was performed on 5 young children suspected as foreign body aspiration who had been admitted on the Department of Pediatrics, Kyung Hee University Hospital from May 1986 to January 1988. The results were as follows: 1) All children had been showed perfusion defect as compatible as acute obstructive lung disease by lung perfusion scan and foreign bodies in bronchial tree were proved on...
A Case of Tsutsugamushi Disease.
Tae Kyu Hame, Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(8):1048-1053.   Published online August 31, 1988
Rickettsial infection has not been identified in Korea since about 20-30 years before in Korea. However, there has been an increasing incidence of Tsutsugamushi disease in recent years. Tsutsugamushi disease is a variety of rickettsial infection to human causing abrupt onset of fever, headadie, vomiting, myalgia, and abdominal pain. In severe case, causing D.I.C., pulmonary edema, hypoalbuminemia and generalized edema. We reported a case of...
A Study of Maternal IgG Anti-A, B in ABO Hemolytic Disease of Newborn: Relation between Antibody titer in Mother and Clinical Severity in Neonate.
Chong Woo Bae, yong Mook Choi, Chang Il Ahn, Hyun Sook Chi
Clin Exp Pediatr. 1988;31(8):999-1006.   Published online August 31, 1988
Only IgG anti-A, or Anti-B cross the placenta and are responsible for the occurrence of ABO hemolytic disease of newbom(HDN). We have conducted the role of IgG anti-A or anti-B in mothers to occurrence and severity of the disease with were related to the level of antibodies in pathogenesis of ABO-HDN. This report presents the relation between the degree of bilirubin, hemoglobin concentration in ABO-HDN...
Iron Deficiency Anemia in Childhood and Diagnostic Significance of Serum Ferritin.
Dong Hyub Lee, Ki Hong Park, Kyu Chul Choi, Yong Mook Choi
Clin Exp Pediatr. 1988;31(5):577-583.   Published online May 31, 1988
In order to elucidate clinical and laboratory findings of the iron deficiency anemia(IDA) in childhood along with diagnostic significance of serum ferritin, 207 patients were analyzed retrospec- tively, who were hospitalized at Department of Pediatrics, Kyung Hee University Hospital from January 1981 to December 1986. The results were as follows; 1) The incidence of IDA in In-Patient was 1.6%. 2) The sex ratio of male to female was...
A Case of Myositis Ossificans Progressiva.
Yoeng Ho Ra, Sung Ho Cha, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):271-275.   Published online February 28, 1988
A cases of Myositis ossificans progressiva in a 3 year-old girl who presented with hard mass in her right buttock and progressive hardening of muscles of her back and neck. The diagnosis was made on the basis of typical clinical features and characeristic radiologic findings. In addition to the cases report, a review of related literatures were discussed.
The Role of Anitiplatelet Antibody and the Therapeutic Effect of High-Dose I.V. gamma-globulin in Childhood Idiopathic Thrombocytopenic Purpura.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1988;31(2):212-219.   Published online February 28, 1988
Among 48 children with I.T.P (26 acute, 10 chronic and 12 undetermined), the antiplatelet antibody test (APA) was qualitatively studied by indirect immunofluorescent method in 34 patients of which only 25 patients (18 acute and 7 chronic) were able to follow-up. The overall positivity of APA was 36% and there was no relationship with disease chronicity. Intravenous r-globulin was given at a dose of...
Clinical and Statistical Observations of Bleeding Disorders in Childhood.
Ha Young Lee, Chong Sung Chung, Kyu Chul Choi, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):186-195.   Published online February 28, 1988
Upper Gastrointestinal Fiberoptic Endoscopy in Children.
Dong Hyup Lee, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Il Min
Clin Exp Pediatr. 1987;30(8):868-873.   Published online August 31, 1987
We observed 63 cases ranging in age from 3 years to 15 years seen by gastrofibroscopy in Dept, of Int. Med. and Dept, of Ped. of Kyung hee Univ. Hospital from January 1980 to December 1985 and following results were obtained 1) The male to female ratio was about 1:1.17. The frequency of the age distribution was 1.6% below 5 years, 25.4% in 6-10 years...
A Clinical Study on Patients with Mycoplasma Pneumoniae Pneumonia in Childhood.
Yeong Ho Ra, Sung Ho Cha, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(7):759-768.   Published online July 31, 1987
Clinical features of 96 cases (46 Mycoplasmal pneumonia: Group I, 50 Non-Mycoplasmal pneumo- nia: Group II) above 2 years of age were studied prospectively from December, 1985 to June, 1986 who were admitted to the Dept, of Pediatrics, Kyung Hee University Hospital. The summary of the study is as follows: 1) Among the total 96 cases with pneumonia above 2 years of age, the frequency...
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
Significance of Brain CT in Children with Meningitig.
Myeong Yeon Lee, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(6):640-650.   Published online June 30, 1987
This study was undertaken to evaluate the significance of brain CT in children with meningitis. The findings of brain CT in 71 children with meningitis were evaluated in relation to the clinical outcome. We divided 71 cases into 5 groups according to clinical outcome on discharge, that is, Group I: Recovery. Group II: Discharge with improvement. Group III: Discharge with residual sequalae. Group IV:...
Clinico-Hematologic Observation of Neonatal Hemolytic Disease due to Minor Blood Group Isoimmunization.
Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Hyun sok Chi
Clin Exp Pediatr. 1987;30(5):504-510.   Published online May 31, 1987
The isoimmune hemolytic diseases of the newborn due to minor blood group are characterized by the abnormal titer of minor group antibody in mother’s serum and neonatal progressive jaundice caused by isoimmune hemolytic anemia. This report present the clinico-hematologic features of six cases of hemolytic diseases of newborn due to minor blood group isoimmunization who were admitted to the Kyung Hee university Hospital and presented...
Statistical Analysis of The Tomors Below 20 Years of Age.
Sang Ho Park, Kyu Chul Choi, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1986;29(8):888-897.   Published online August 31, 1986
Total 460 cases of benign and malignant tumors below 20 years of age who admitted to Kyung Hee University Hospital for 5 years from January 1980 to December 1984 were clinically analized and the following results were obtained.1) Among 460 benign and malignant tumors, malignant tumors were 201 cases(43.7%) and benign tumors were 259 cases(56.3%). 2) The male to female incidence ratio was...
Role of Lumbar Puncture in Children with First Febrile Convulsion.
Kyu Chul Choi, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1984;27(7):718-724.   Published online July 31, 1984
To assess the role of lumbar puncture in the children with their first febrile convulsion, the results of lumbar puncture in 154 children for a 3-year period were reviewed. In the frequency of the causes of febrile convulsion, meningitis and encephalitis were the most common (34.4%) and upper respiratory tract infection was the next(26.0%). The comparison and observations between the...