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Volume 56(10); Oct 2013
Review Articles
Vitamin D status and childhood health
Youn Ho Shin, Hye Jung Shin, Yong-Jae Lee
Korean J Pediatr. 2013;56(10):417-423.   Published online October 31, 2013

Vitamin D is an essential component of bone and mineral metabolism; its deficiency causes growth retardation and skeletal deformities in children and osteomalacia and osteoporosis in adults. Hypovitaminosis D (vitamin D insufficiency or deficiency) is observed not only in adults but also in infants, children, and adolescents. Previous studies suggest that sufficient serum vitamin D levels should be maintained in...

Measurements of fractional exhaled nitric oxide in pediatric asthma
Youn-Soo Hahn
Korean J Pediatr. 2013;56(10):424-430.   Published online October 31, 2013

Exhaled nitric oxide (NO) has been extensively investigated as a noninvasive marker of airway inflammation in asthma. The increased NO expression induced by inflammatory mediators in airways can be monitored easily in exhaled air from asthmatic children. Based on the relationship between the increased NO expression and eosinophilic airway inflammation, fractional exhaled nitric oxide (FeNO) measurements become an important adjunct...

Magnetoencephalography in pediatric epilepsy
Hunmin Kim, Chun Kee Chung, Hee Hwang
Korean J Pediatr. 2013;56(10):431-438.   Published online October 31, 2013

Magnetoencephalography (MEG) records the magnetic field generated by electrical activity of cortical neurons. The signal is not distorted or attenuated, and it is contactless recording that can be performed comfortably even for longer than an hour. It has excellent and decent temporal resolution, especially when it is combined with the patient's own brain magnetic resonance imaging (magnetic source imaging). Data...

Original Articles
Association between cord blood 25-hydroxyvitamin D concentrations and respiratory tract infections in the first 6 months of age in a Korean population: a birth cohort study (COCOA)
Youn Ho Shin, Jinho Yu, Kyung Won Kim, Kangmo Ahn, Seo-Ah Hong, Eun Lee, Song-I Yang, Young-Ho Jung, Hyung Young Kim, Ju-Hee Seo, Ji-Won Kwon, Byoung-Ju Kim, Hyo-Bin Kim, Jung Yeon Shim, Woo Kyung Kim, Dae Jin Song, So-Yeon Lee, Soo Young Lee, Gwang Cheon Jang, Dong In Suh, Hyeon-Jong Yang, Bong Sung Kim, Suk-Joo Choi, Soo-Young Oh, Ja-Young Kwon, Kyung-Ju Lee, Hee Jin Park, Pil Ryang Lee, Hye-Sung Won, Soo-Jong Hong
Korean J Pediatr. 2013;56(10):439-445.   Published online October 31, 2013
Purpose

Previous studies suggest that the concentration of 25-hydroxyvitamin D [25(OH)D] in cord blood may show an inverse association with respiratory tract infections (RTI) during childhood. The aim of the present study was to examine the influence of 25(OH)D concentrations in cord blood on infant RTI in a Korean birth cohort.

Methods

The levels of 25(OH)D in cord blood obtained from 525 Korean...

Susceptibility of rat hippocampal neurons to hypothermia during development
Kyung Ah Seo, Sehhyun Kim, Na Mi Lee, Soo Ahn Chae
Korean J Pediatr. 2013;56(10):446-450.   Published online October 31, 2013
Purpose

This study evaluated the extent of damage due to hypothermia in the mature and immature brain.

Methods

Hippocampal tissue cultures at 7 and 14 days in vitro (DIV) were used to represent the immature and mature brain, respectively. The cultures were exposed at 25℃ for 0, 10, 30, and 60 minutes (n=30 in each subgroup). Propidium iodide fluorescent images were captured 24...

Case Reports
Parotid sialolithiasis in a two-year-old boy
Do Hoon Kim, Woo Sun Song, Yeong Jin Kim, Won Duck Kim
Korean J Pediatr. 2013;56(10):451-455.   Published online October 31, 2013

Sialolithiasis is caused by the obstruction of a salivary gland or its excretory duct by the formation of calcareous concretions or sialoliths; this results in salivary ectasia and provokes subsequent dilation of the salivary gland. Sialolithiasis is relatively common, accounting for 30% of salivary diseases; however, it is rarely observed in childhood. This case report describes a 2-year-old male patient...

Cystic fibrosis of pancreas and nephrotic syndrome: a rare association
Selvi Kelekçi, Müsemma Karabel, Aydın Ece, Velat Şen, Ali Güneş, İlyas Yolbaş, Cahit Şahin
Korean J Pediatr. 2013;56(10):456-458.   Published online October 31, 2013

Cystic fibrosis (CF) is a genetic disease with autosomal recessive inheritance and is common in Caucasian people. The prevalence of this disease is between 1/2,000 and 1/3,500 live births, and the incidence varies between populations. Although the CF transmembrane conductance regulator gene is expressed in the kidneys, renal involvement is rare. With advances in the treatment of CF, life expectancy...