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The intracellular pH was determined from the cardiac muscles in rabbits from 12 normal, 12 acute
metabolic acidosis and 9 acute metabolic alkalosis, using 5, 5~dimethyl-2, 4-oxazolidinedione (DMO)
method. Metabolic acidosis was produced by intravenous infusion of hydrochloric acid and metabolic
alkalosis by sodium bicarbonate solution.
The relationship between intracellular and extracellular hydrogen ion concentrations and electrocar-
diographic patterns were also studied and... |