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Volume 41(3); Mar 1998
Medical Lecture Course
Genetic Counseling
Kibok Kim
J Korean Pediatr Soc. 1998;41(3):293-298.   Published online March 15, 1998
Original Articles
The Efficacy of Fetal Ultrasonography and Postnatal Abdominal Ultrasonography for the Diagnosis of Neonatal Abdominal Mass
Hee Eun Lee, Ee Kyung Kim, Hee Seok Kim, Yun Kyoung Lee, Chan Hwu Park, Kyung Ran Park, June Dong Park, Beyong Il Kim, Woong Heum Kim, Jung Hwan Choi, Gui Won Park, Hwang Choi, Yong Choi, Chong Ku Yun
J Korean Pediatr Soc. 1998;41(3):299-306.   Published online March 15, 1998
Purpose : Most neonatal abdominal masses are benign in nature, but early detection and management is important to avoid the development of complications. So, we studied the causes of neonatal abdominal masses and the efficacy of ultrasonography for early detection and diagnosis. Methods : We reviewed 36 newborn infants with abdominal masses who had been admitted to the nursery and Neonatal...
A Survey on the Attitudes toward Premature Infants
Oh Hyuk Kwon, Son Moon Shin
J Korean Pediatr Soc. 1998;41(3):307-314.   Published online March 15, 1998
Purpose : We studied the attitudes of general population and medical personnels toward premature infants to establish basic data about prematurity. Methods : Ten students from Yeungnam University College of Medicine conducted field surveys on the general population at residential and commercial districts, and on medical personnels at private local clinics and hospitals in Taegu with a prepared questionaire from July...
Clinical Change of Mycoplasma Pneumonia
Jae Bum Lee, Kyong Tae Whang, Jeong Hyun Kim, Kyong Og Ko, Ji Hee Cho, Yun Duk Yoo
J Korean Pediatr Soc. 1998;41(3):315-322.   Published online March 15, 1998
Purpose : It was noted some changes of clinical manifestations of mycoplasma pneumonia. we reviewed and compared these changes and saught any clues causes for proper dignosis and treatment. Methods : We divided patients with mycoplasma pneumonia into two groups, Group 1(from Jan. to Dec. 1996) and Group 2(from Jan. to Dec. 1994), and analyzed clinical, radiologic, and serologic differences. Results :...
Therapeutic Efficacy of Dual Therapy and Triple Therapy for Helicobacter pylori Infection in Children
Sun-Hwan Bae, Jae-Sung Koh, Jeong-Kee Seo
J Korean Pediatr Soc. 1998;41(3):323-330.   Published online March 15, 1998
Purpose : An optimal treatment for Helicobacter pylori (H. pylori ) infection in children has not yet been established. In this study, the efficacy and the tolerability of triple therapy with colloidal bismuth subcitrate(CBS), amoxicillin and metronidazole, were evaluated in comparison with dual therapy with CBS and amoxicllin. Methods : Eighty-six children with H. pylori infection, aged 6 years to 14...
The Treatment of Croup with Nebulized Budesonide and Intramuscular Dexamethasone
Jung Woo Lee, Young Ho Rah, Chong-Woo Bae, Sa Jun Chung, Yong Mook Choi
J Korean Pediatr Soc. 1998;41(3):331-337.   Published online March 15, 1998
Purpose : Steroids have anti-inflammatory effects which reduces inflammation and edema of the tissue. Thus, corticosteroids have been used for treatment of croup. The aim this study is to compare and assess the effects of intramuscularly injected dexamethasone and nebulized budesonide in treatment of moderate or severe croup. Methods : Between July 1995 to June 1996, we have assessed 44 inpatients...
Normal Predicted Values of Pulmonary Function Test in Healthy Korean Children
Seung Yeon Nam, Kyung Hyo Kim, Young Mi Hong, Gyoung Hee Kim
J Korean Pediatr Soc. 1998;41(3):338-345.   Published online March 15, 1998
Purpose : We performed a pulmonary function test with simple, computerized spirometry composed of pneumotachometry and evaluated the predicted normal values of air flow rates and lung volumes in healthy Korean children. We calculated each of the simple and complex linear and logarithmic regression equations setting the predicted values. Methods : Four hundred and fifty-two healthy children were enrolled from December, 1994 to August, 1995....
Total Anomalous Pulmonary Venous Connection : The Results of 23 Consecutive Patients
Young-Hwue Kim, Jae-Kon Ko, In-Sook Park, Tae-Jin Yun, Dong-Man Seo, Chang-Yee Hong
J Korean Pediatr Soc. 1998;41(3):346-353.   Published online March 15, 1998
Purpose : Surgical risk of total anomalous pulmonary venous connection(TAPVC) is high, especially in patients with early presentation resulting from pulmonary venous obstruction or with advanced pulmonary vascular obstructive disease(PVOD). We reviewed our experience of primary correction of TAPVC and examined the surgical outcome and risk factors. Methods : From June 1991 to Sept. 1996, 23 neonates or infants who were...
Congenital Heart Disease and Associated Extracardiac Anomalies in Autopsies
Soon Seong Park, Myeong Ja Yoon, Jeong Sun Kim, Jeong Wook Seo, Chung Il Noh, Jung Yun Choi, Yong Soo Yoon, Byung Il Kim, Joong Hwan Choi, Chong Ku Yoon
J Korean Pediatr Soc. 1998;41(3):354-362.   Published online March 15, 1998
Purpose : In order to find out how frequently and what kind of extra-cardiac anomalies (CAs) is associated with congenital heart disease(CHD) in general and in each CAs, autopsies with congenital cardiovascular malformations were studied. Methods : Autopsy files of Seoul National University Children' s Hospital from 1991 to 1995 were reviewed to find cases of CHDs. Other extra-CAs were tabulated from the records...
Incidence of Congenital Heart Disease in Neonate by Color Doppler Echocardiography
Tae Chan Kwon, Joon Sik Kim, Sang Lak Lee, Myung Sung Kim, Geun Soo Park, Chun Soo Kim, In Joo Kim, Bin Ahn
J Korean Pediatr Soc. 1998;41(3):363-368.   Published online March 15, 1998
Purpose : Many reports exist about the frequency of congenital heart disease(CHD) in the world, but according to the definition of CHD and subjects of study group, many differences existed between the reports. We conducted this study to evaluate the incidence and frequency of CHD by color Doppler echocardiography in neonate, and to suggest a preliminary model of incidence of...
Percutaneous Closure of Patent Ductus Arteriosus Using Coil Embolization
Mi Jung Kang, Sejung Sohn, Eun Jung Bae, In Seng Park, Seong Ho Kim
J Korean Pediatr Soc. 1998;41(3):369-377.   Published online March 15, 1998
Purpose : Percutaneous closure with occluding coils has been recently described as a method of nonsurgical treatment of the small patent ductus arteriosus(PDA). The snare-assisted technique or detachable coil has been newly developed, improving coil delivery and eliminating the incidence of coil embolization. This method is also applicable to residual PDA following surgical ligation or device implantation. The study purpose...
Random Urine Ca/Cr Ratio in Healthy Neonates
Hea Young Lee, So Young Park, Eun Sun Yoo, Eun Ae Park, Seung Joo Lee
J Korean Pediatr Soc. 1998;41(3):378-382.   Published online March 15, 1998
Purpose : Recently, in high risk preterm infants, we experienced high incidence of hypercalciuria, nephrolithiasis & nephrocalcinosis. To screen hypercalciuria, we need the normal value of random urine Ca/Cr ratio in healthy neonates according to gestational age, postnatal age, milk and calcium intake. Methods : Random urine Ca/Cr ratio was checked in 260 healthy full-term infants at the 2-7th day, and...
Expression of Tumor Suppression Gene in Childhood Cancer
Ji Eun Lee, Myung Ik Lee, Chang Soo Park
J Korean Pediatr Soc. 1998;41(3):383-389.   Published online March 15, 1998
Purpose : Childhood cancer is closely related to the mutation of tumor suppressor gene. The mutant gene may evoke congenital anomaly and development of cancer. The common solid tumors in childhood are Wilms' tumor, retinoblastoma and neuroblastoma. The cytogenetic study has been performed. The cytogentic study revealed structural abnormality of chromosome in Wilms' tumor and retinoblastoma. The oncogene and mutation...
Case Reports
A Case of DiGeorge Syndrome
Young Joo Son, Yu Sik Jeon, Soon Lee Jung, Kyuchul Choeh
J Korean Pediatr Soc. 1998;41(3):390-395.   Published online March 15, 1998
We experienced a case of DiGeorge syndrome in a 25-day-old male infant presented with micrognathia, short neck, fish-shaped mouth and intractable seizures with a loading dose of phenobarbital & dilantin. The serum calcium level was 3.7mg/dl, ionized calcium level was 0.62mmol/L, and parathyroid hormone carboxy-terminal level was 0.01ng/ml. We treated with it calcium gluconate infusion, low phosphorous formula milk feeding, and...
A Case of VATER association Variant with a 46,XY,inv(6)(q11q16) Inversion
Dong-Ho Park, Dae-Bong Jung, Kyoung Rae Moon, Yeong-Bong Park, Sang-Kee Park
J Korean Pediatr Soc. 1998;41(3):396-400.   Published online March 15, 1998
VATER association of vertebral defects, imperforate anus, tracheoesophageal(T-E) fistula with esiphageal atresia, and radial and renal dysplasia are utilized to identify this complex. Other anomalies are vascular anomalies(cardiac defects and single umbilical artery), and prenatal and postnatal growth deficiency, defects of external genital and urinary tract as well as bone defects (preaxial lower extremity anomalies, supernumerary digits, rib anomaly). This pattern of malformation generally occurs...
Two Cases of Factor XI Deficiency in Sisters
Yun-Kyeong Cho, Jae-Young Lim, Yang-Suk Jung, Chan-Hoo Park, Hyang-Ok Woo, Byung-Kiu Park, Hee-Shang Youn
J Korean Pediatr Soc. 1998;41(3):401-404.   Published online March 15, 1998
We experienced two cases of factor XI deficiency in a 5 yearr 7 month-old girl, whose chief complaint was coke-colored gross hematuria, and her 9-year-old elder sister. The laboratory findings were prolonged aPTT and prominent deficiency of factor XI. The gross hematuria of the index case was identified due to acute poststreptococcal glomerulonephritis. So we report two cases of factor...
Two Cases of Leigh Disease
Seong Hun Kim, Soo En Park, Ju Seok Lee, Sang Ook Nam, Yeong Tak Lim
J Korean Pediatr Soc. 1998;41(3):405-409.   Published online March 15, 1998
Leigh Disease, or subacute necrotizing encephalopathy(SNE), is a degenerative disorder characterized by lesions of the gray and white matter in the bran and spinal cord. The pathogenesis was known as mitochondrial enzyme defect of the respiratory chain system. We experienced 2 cases of Leigh disease. The first case, a seven-month old girl who was presented with weak respiration and failure...
A Case of Alagille Syndrome
Eun Kyung Hwang, Gwang Hoon Lee, Eell Ryoo, Kang Ho Cho, Gil Hyun Kim, Hak Soo Lee, Ji Hye Kim, Sung Hae Park, Hee Sup Kim
J Korean Pediatr Soc. 1998;41(3):410-414.   Published online March 15, 1998
Alagille syndrome is characterized by chronic cholestasis, posterior embryotoxon, skeletal abnormalities, cardiovascular abnormalities, and a typical face with prominent forehead and pointed chin. Its histological feature includes paucity of interlobular bile ducts. We experienced a 49-day-old female infant presenting with frequent upper respiratory tract infection and persistent jaundice. She had a typical face and chronic cholestasis. Echocardiograms revealed peripheral pulmonary...
A Case of Congenital Nephrotic Syndrome due to Diffuse Mesangial Sclerosis
Jung-Jin Yu, Dong Kyu Jin, Hae Il Cheong, Hyun Soon Lee, Yong Choi
J Korean Pediatr Soc. 1998;41(3):415-419.   Published online March 15, 1998
Diffuse mesangial sclerosis(DMS) is one of the underlying pathology of congenital and infantile nephrotic syndrome. Infants with DMS develop nephrotic syndrome before 2 years of age and progress to end stage renal disease within 3 years of age. The authors experienced a case of isolated DMS in a 4-month-old male infant who had nephrotic syndrome for 1 month. The diagnosis...
A Case of Secondary Hemosiderosis and Hepatic Fibrosis in a Pateint with Acute Myelogenous Leukemia
Hyoung No Kim, Jae Won Huh, Jae Sun Park
J Korean Pediatr Soc. 1998;41(3):420-424.   Published online March 15, 1998
Chronic iron overload is associated with life-threatening complications, such as cardiomyopathy, liver cirrhosis, diabetes, hypothyroidism, hypoparathyroidism and hypogonadism. We experienced a case of secondary hemosiderosis with hepatic fibrosis in a 8-year-old boy who had been transfused 56 pints of packed red blood cells for a supportive therapy of acute myelogenous leukemia for a 27-month period. Intramuscular injection of Desferroxamine(40mg/kg/day) was...