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Volume 47(3); Mar 2004
Clinical Lectures
Helicobacter pylori Infection in Children : Recommendations for Diagnosis and Treatment
Yon Ho Choe
Korean J Pediatr. 2004;47(3):235-239.   Published online March 15, 2004
Helicobacter pylori(H. pylori) infection is mainly acquired in childhood. The prevalence of infection is still highest in children in the developing world. There has been a need for clinical guidelines for H. pylori infection in children. Therefore, the North American Society for Pediatric Gastroenterology and Nutrition and the European Paediatric Task Force on H. pylori achieved consensus and developed clinical...
Food Allergy
Soo-Young Lee
Korean J Pediatr. 2004;47(3):240-246.   Published online March 15, 2004
Food allergy is one of the clinical clusters due to food-induced allergic inflammation against dietary proteins which induced by IgE-mediated and/or non-IgE mediated mechanisms. Food allergic reactions are responsible for a variety of clinical symptoms involving the skin, gastrointestinal tract, and respiratory tract. Sometimes the life threatening anaphylactic reactions would be induced, especially by peanuts, tree nuts and buckwheat allergy....
Original Articles
Trend of Obesity in School Age Children in Seoul Over the Past 23 Years
Young Shin Park, Dong Hwan Lee, Joong-Myung Choi, Yun Ju Kang, Chong Hee Kim
Korean J Pediatr. 2004;47(3):247-257.   Published online March 15, 2004
Purpose : The aim of this study was to evaluate the change in prevalence and the epidemiology of obesity in school age children of Seoul, Korea during the last 23 years with coherency and under the same standards. Methods : We used the new 1998 standard weight for height to calculate obesity on the personal data from five years and produced...
The Relationship between the Perception of Height and Self-Esteem in Children
Mi Jin Kim, Young Il Rho, Eun Seok Yang, Kyung Rye Moon, Sang Kee Park, Yeong Bong Park, Eun Young Kim
Korean J Pediatr. 2004;47(3):258-263.   Published online March 15, 2004
Purpose : The aim of this study was to evaluate the behavioral and affective characteristics of children who thought they were short. Methods : Fifteen hundred and twenty-two students of four elementary and middle schools in Gwangju City completed a battery of questionnaires asking about stature-related stress, self-esteem, and personality characteristics. The children were divided into three groups and compared according...
Observation on Causes of Adoption and Social Background of Children in Adoption Institution(5th Report)
Hak Sung Kim, Soo Yeon Kim, Sun Hee Kong, Dong Woo Lee, Kyung Eun Kim, Hye Jung Shin, Jae Yoon Kim
Korean J Pediatr. 2004;47(3):264-268.   Published online March 15, 2004
Purpose : Through a review of data provided by an adoption institution, this study was designed to provide a clue to help to reduce the abandonment of children by comparing the conditions at birth, social background, reason for request for adoption, and the degree of dependence on foreign adoption compared with the previous four reports. Methods : A total of 445...
The Effect of Post-natal Weight Changes on the Development of Bronchopulmonary Dysplasia in Infants with Respiratory Distress Syndrome
Hye One Jhon, Young Min Kim, Hee Joo Hong, Chong Woo Bae
Korean J Pediatr. 2004;47(3):269-274.   Published online March 15, 2004
Purpose : The subjects were compared and measured for differences in the aspects of weight changes between the groups that developed bronchopulmonary dysplasia(BPD) after treatment and those that did not, to analyze the relations between the patterns of early weight change after birth and the development of BPD. Methods : Retrospective analysis of medical records were performed for birth weight and...
Risk Factors of Nephrocalcinosis in Very Low Birth Weight(VLBW) Infants
Gyu Hong Shim, Jin A Lee, Yun Jung Shin, Ee Kyung Kim, June Dong Park, Beyong Il Kim, Jung Hwan Choi
Korean J Pediatr. 2004;47(3):275-281.   Published online March 15, 2004
Purpose : Nephrocalcinosis in very low birth weight(VLBW) infants were known to be caused by a longer duration of furosemide use. However, etiologies, pathogenesis and risk factors remain unclear. Therefore, we examined the incidence and risk factors of nephrocalcinosis in VLBW infants retrospectively. Methods : Inborn babies of birth weights less than 1,500 gm were examined retrospectively. Data were reviewed on...
Natural History of Chronic Hepatitis B in Children
Yuria Kim, Seoung Yeon Baek, Ji Hyun Eom, Ki Sup Chung
Korean J Pediatr. 2004;47(3):282-289.   Published online March 15, 2004
Purpose : We investigated the spontaneous seroconversion rate of hepatitis B viral markers and predictive factors affecting seroconversion in children with chronic hepatitis B. Methods : The study population included 214 children diagnosed as chronic hepatitis B, with positive HBsAg, HBeAg and HBVDNA over six months, and all patients had a family history of chronic Hepatitis B. They were followed between...
Utility of Abdominal Computerized Tomography in Diagnosis of Acute Appendicitis
Su Jin Sung, Ji Young Yeoun, Seong Hoon Lee
Korean J Pediatr. 2004;47(3):290-293.   Published online March 15, 2004
Purpose : To evaluate the accuracy of ultrasonography(USG) and abdominal computerized tomography(CT) and the possibility of reducing unnecessary appendectomy rate with improvement of diagnostic accuracy using optional CT with USG. Methods : From January 1999 to May 2003, 496 patients younger than 14 years received surgical intervention with preoperative impression of acute appendicitis. They were devided into three groups no...
Congenital Heart Disease in Jeju : Postnatal Incidence and Clinical Features
Jung Ha Lee, Gyu Hong Shim, Kyung Sue Shin, Jung Yun Hong, Yeoun Woo Kim, Seong Ho Kim, Chung Il Noh
Korean J Pediatr. 2004;47(3):294-303.   Published online March 15, 2004
Purpose : This is a retrospective descriptive study to determine the incidence of congenital heart disease(CHD) in Jeju and to estimate the suitability of the Jeju population as the subject for a regional birth cohort study. Methods : All patients with CHD diagnosed by two dimensional echocardiography in Cheju National University Hospital and Halla General Hospital from January 1999 to...
Characteristics of Pulmonary Atresia and Ventricular Septal Defect According to Morphologic Classification and Changes of Pulmonary Artery after Modified B-T Shunt
Kise Nam, Jeong Hoon Kim, Jae Young Choi, Jun Hee Sul, Sung Kue Lee, Young Hwan Park
Korean J Pediatr. 2004;47(3):304-309.   Published online March 15, 2004
Purpose : The purpose of this study is to help determine the optimal time and method for operation of pulmonary atresia(PA) with ventricular septal defect(VSD). Methods : Seventy patients who were diagnosed as PA with VSD in the Pediatric Department of Cardiology, Severance Hospital between May, 1991 and April, 1995, were included in our study. Subjects were divided into two groups...
The Effect of Growth Hormone on Patients with Growth Hormone Deficiency and Idiopathic Short Stature
Jeong Cheol Kang, Yoon Suk Choi, In Kyong Choi, Ho Sung Kim, Duk Hee Kim
Korean J Pediatr. 2004;47(3):310-318.   Published online March 15, 2004
Purpose : This study was designed to evaluate the effect of growth hormones on children with growth hormone deficiency(GHD) or idiopathic short stature(ISS). Methods : Between January 1988 to July 2003, 45 patients(M26, F19) with GHD and 24 patients (M13, F11) with ISS were enrolled in this study. Height standard deviation score(Ht SDS) for chronological age(CA) and Ht SDS for bone...
Effects of Intestinal Ischemia on Intestinal Mucosal Damage and Effects of Interleukin-10 in Young Murine Model
Young-Shil Park, Dong-Chul Kim, Chung-Sik Chun
Korean J Pediatr. 2004;47(3):319-324.   Published online March 15, 2004
Purpose : Intestinal vascular ischemia is the most probable pathogenesis in the development of necrotizing enterocolitis in prematures. The authors studied the histology of intestinal mucosal damage by clamping the superior mesenteric artery in 35 rats, and, analyzed the histologic scores between young rats(I) and adult rats(II) groups according to clamping times(15, 30 and 60 minutes) and compared the effect...
Case Reports
Angiotensin Converting Enzyme Inhibition Modulates Mitogen Activated Protein Kinase Family Expressions in the Neonatal Rat Kidney
Byung Min Choi, Mee-Hye Oh, Kee Hwan Yoo
Korean J Pediatr. 2004;47(3):325-331.   Published online March 15, 2004
Purpose : In a developing kidney, the renin-angiotensin system(RAS) is markedly activated and is thought to play an important role in postnatal renal growth and maturation. We previously demonstrated that angiotensin converting enzyme(ACE) inhibition in a developing rat kidney increases apoptosis and decreases its related gene expressions, which may account for renal growth impairment. Among the mitogen-activated protein kinases(MAPK) family...
Three Cases of Hypercalcemia Due to Vitamin D Intoxication in Infancy
Jin-Ho Choi, Mi-Sun Yum, Hyewon Hahn, Young Seo Park
Korean J Pediatr. 2004;47(3):332-337.   Published online March 15, 2004
Hypercalcemia in infancy is an uncommon disorder but has a potential of serious sequelae. Therefore, infants with hypercalcemia must be promptly investigated and need urgent management. We report three cases of infantile hypercalcemia caused by vitamin D intoxication, emphasizing diagnostic investigations and the course of treatment. The first and the second cases were thought to be vitamin D intoxication without...
Two Pediatric Patients with Neutropenia and Thrombocytopenia Associated with Parvovirus B19 Infection
Dong Koo Kim, Young Dai Kim, Ho Jun Lim, Sung Hee Oh, Hahng Lee
Korean J Pediatr. 2004;47(3):338-342.   Published online March 15, 2004
Parvovirus B19, a member of the Erythrovirus genus, is the only member of the Parvoviridae family known to be pathogenic in humans. Haematological consequences of B19 infection arise due to a direct cytotoxic effect on erythroid progenitors in bone marrow, resulting in interruption of erythrocyte production. The physiology of host haematopoiesis and competence of the immune response each determines clinical...
A Case of Dieulafoy's Lesion in Duodenal Bulb
Jung Woo Rhim, Young Seok Kim, Jae Ock Park
Korean J Pediatr. 2004;47(3):343-346.   Published online March 15, 2004
Dieulafoy's lesion is an uncommon cause of recurrent massive gastrointestinal bleeding resulting from an abnormally large submucosal artery that protrudes through a small mucosal defect. Incidence of Dieulafoy's lesion as a source of upper gastrointestinal bleeding ranges from 0.3 to 6.7% in adults. But recently, the incidence is on an increasing trend by advanced endoscopic diagnostic technique. Lesions may occur...