Clinical and Experimental Pediatrics

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Case Report

Two Cases of Congenital Paraesophageal Hiatal Hernia in Infancy

Ji Yeon Hong, Kih Yeon Song, Woo Ki Lee, Kwang Woo Kim, Jong Gon Ha, Soon Ok Choi

Clin Exp Pediatr. 2000;43(12):1613-1620. Published online December 15, 2000

Herniation of the stomach through the esophageal hiatus into the posterior mediastinum is a commom affliction of humans. The incidence of hiatal hernia is difficult to determine because of the absence of symptoms in a large number of patients. Hiatal hernias are classified into two major types; type I sliding hiatal hernia and type II paraesophageal hiatal hernia. Sliding hernia...

Original Article

Plasma Levels of Oral Methotrexate in Children Receiving Maintenance Chemotherapy for Acute Lymphocytic Leukemia

Soo Kwan Lee, Kih Yeon Song, Young Hee Hwang, Young Hwan Lee, Jeong Ok Hah, Chun Dong Kim

Clin Exp Pediatr. 1993;36(7):936-943. Published online July 15, 1993

This study was conducted to investigate plasma levels of oral methotrexate in rabbits and children receiving maintenance chemotherapy for acute lymphocytic leukemia. Eight New Zealand white rabbits, weighing 2kg in body weight, were divided into 3 groups and 5mg of methotrexate from 3 different manufactorying company was administered to the each group rabbits via nasogastric tube. Time to peak concentration ranged from...

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