Natural history and consequences of the novel 2009 influenza A H1N1 (2009 H1N1) infection in immunocompromised pediatric patients are not yet fully understood. In this study, we investigated the clinical features and outcomes of the 2009 H1N1 infection in pediatric patients with hematological and oncological diseases. We retrospectively reviewed the medical records of 528 patients who had hematological and oncological diseases... |
Purpose : Iron deficiency anemia (IDA) is one of the most common nutritional deficiencies in children on a weaning diet. We investigated weaning practices in infants and children, as well as their mothers' knowledge about weaning. Methods : We investigated 129 children with IDA and 166 without IDA (aged 6-36 months) who had visited 10 university hospitals between March 2006... |
Purpose : Chromosome analysis is important in genetic study and genetic counseling. This study was performed to evaluate the type and incidence of chromosome abnormalities in a single hospital for 25 years. Methods : Chromosome analyses were performed on peripheral blood lymphocytes, obtained from 4,856 patients with suspected chromosomal aberrations, referred to cytogenetic laboratory in Department of Pediatrics, Kyungpook National... |
Purpose : This study was performed to evaluate the recent frequency of karyotypes in different sex chromosome abnormalities and to evaluate the age and clinical manifestations at diagnosis. Methods : Peripheral blood leukocytes were obtained from subjects who were clinically suspected to have sex chromosome abnormalities and referred to the cytogenetic laboratory in the Department of Pediatrics, Kyungpook National University Hospital... |
Purpose : Leukoencephalopathy(LE) is one of the most serious complications in children with hematologic malignancies during the course of treatment. Early recognition is important to reduce the impact and sequelae from LE. We therefore investigated the clinical features of LE following central nervous system(CNS) prophylaxis in children with hematologic malignancies and evaluated the significance of regular check-ups of brain MRI. Methods... |
Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions. There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances. At the present time it appears that a... |
The clinical characteristics and laboratory data in the twenty six patients of hemophilia diagnosed in the Department of Pediatrics, Kyungpook National University Hospital for 8 years from 1983 were evaluated. The following results were obtained: Twenty one cases (80.7%) were diagnosed as hemophilia A and five cases (19.3%) as hemophilia B. Eleven cases (42.3%) were diagnosed under one year of age and the... |
A clinical trial was conducted to determine the effect of low-dosage recombinant a-interferon therapy in children with HBs Ag and HBe Ag positive chronic active hepatitis. Studied patients consist of 7 biopsy-proven children (aged 6.5-11.5 yr). After 16 weeks of therapy, following results were obtained. Out of 7 HBe Ag positive cases, 5 cases (71.4%) were converted to HBe Ag negative state. One of two... |
A prospective study was conducted to see the therapeutic effect of iron deficiency anemia on a different oral iron doses. Studied patients consisted of 48 children with iron deficiency anemia who were admitted to our Pediatric Department during January 1988 - September 1989. Three groups were consisted with Group A (element iron dose 3 mg/kg/d, 16 cases), Group B (3 mg/kg/d with vitamin C... |
The following results were obtained from eight cases of hereditary spherocytosis (HS) who were admitted at the Department of Pediatrics, Kyung-pook National University Hospital from July 1984 to January 1989. The percentage of HS among the pediatric hematology patients during the same period was 2.6%. Male amd female were one and seven respectively. The mean age at the diagnosis and at onset of symptom was... |
We investigated the clinical and epidemiological characteristics of rotavirus gastroenteritis in children. The study included 1697 children with acute diarrhea who admitted to the Department of Pediatrics in Hanyang University Hospital from March 1983 through February 1987. The stool specimens were cultured to isolate Campylobacter, Shigella and salmonella and tested for rotavirus by ELISA. The results were 1) Rotavirus was isolated in 646 cases (38.1%) out of total... |
Superoxide dismutase activity of erythrocyte in 20 cases of 21-trisomy Down syndrome between 2 months and 15 years old age and 13 cases of age-matched normal children were checked at Department of Pediatrics and Department of Biochemistry, School of Medicine, Kyung-Pook National University. The results were following: Mean superoxide dismutase activity in normal children was 202.25 U/gmHb and in Down syndrome 291.69 U/gmHb, and the ratio... |
We experienced 3 cases of Glanzmann' s thrombasthenia of 2 year-old boy, 4 year-old boy, and 5 year-old girlt who represented with frequent epistaxis and petechia. The later two of them are brother and sister.Laboratory findings were characterized by normal platelet counts, markedly diminished clot retraction, prolonged bleeding time, positive Rumpel-Leede test, abnormal platelet adhesion to glass, and complete failure... |
Two cases of athyrotic cretinism in a five months old male infant and one month old female infant were Presented. Diagnosis was established by clinical features, thyroid scintigram. X-ray survey of skeletal maturation as biochemical studies. Pertinent literatures were also briefly reviewed. |
Total 114 cases of the patients of nenatal tetanus were clinically evaluated who were admitted to the Department of Pediatrics, Kyungpook National University hospital from Jan. 1967 to Aug. 1976. The results were as follows; 1. The unmber of patients yearly means were about 12 cases whics was 2.7% of total admitted patients of Pediatrics. 2. There was revealed the... |