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Case Report
Thrombolytic Therapy and Long Term Follow-up Study in a Child with Kawasaki Disease Complicated by Giant Coronary Aneurysm with Thrombosis
Su Jung Moon, Su Ya Lee, Kyong Hee Na, Sun Young Park, Eun Young Kim, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2003;46(3):302-307.   Published online March 15, 2003
The long-term clinical issues in Kawasaki disease are concerned with the coronary artery lesions that result in aneurysmal formation, thrombotic occlusion, progression to ischemic heart disease, and premature atherosclerosis. We here report a 3 month old infant with Kawasaki disease complicated by giant coronary aneurysm with thrombosis. After urokinase(10,000 IU/kg) and heparin(400 IU/kg) were injected for two days as thrombolytic...
Original Article
Recurrence Rate of Febrile Seizures by Combining Risk Factors
Su Jung Moon, Gu Ken Sun, Eun Young Kim, Kyong Hee Na, Sun Young Park, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2002;45(11):1403-1410.   Published online November 15, 2002
Purpose : In previous studies, various risk factors for recurrent febrile seizures have been identified. But none of these risk factors alone could sufficiently discriminate children at high or low risk for recurrent seizures. Therefore, we tried to identify patients at high risk of recurrent febrile seizures by combining risk factors. Methods : Two hundred and four children who had...
Case Report
A Case of Fetal Hepatic Calcificaion with a Good Prognosis
Kyong Hee Na, Hyun Jung Lee, Sung Soo Kim, Eun Young Kim, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2002;45(3):395-400.   Published online March 15, 2002
Recently, the increasing use of antenatal high resolutional ultrasonographic studies, and the increasing expertise of sonographers have contributed to the more frequent prenatal detecton of fetal hepatic calcification. Fetal hepatic calcification can arise from peritoneal, ischemic, infectious, neoplastic, and idiopathic causes. There are many reports that the prognosis is good in isolated fetal hepatic calcification without chromosomal aberrations, associated congenital...
Original Article
Assessment of Chromosomal Analyses of 1,180 Cases Suspected of Chromosomal Aberrations
Hyeon Kyoung Jeong, Eun Young Ahn, Sung Soo Rim, Eun Young Kim, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 2002;45(3):311-319.   Published online March 15, 2002
Purpose : We have performed this study to obtain reference data for the distribution of chromosomal aberrations in Korea. Methods : We analyzed 1,180 chromosomal study cases from Kwang ju Christian Hospital during the past 25 years. 756 cases suspected of characteristic chromosomal aberration syndromes and 424 cases with hermaphroditism, mild sexual abnormalities, multiple anomalies, or mental & growth retardation...
The Clinical and Prognostic Survey of The Preterm Infants Delivered from Pregnancy-induced Hypertension Mothers
Seoung Pyo Han, Sang Kee Park, Chang Hoon Song, Jong Park, Kyoung Sim Kim, Young Youn Choi
Clin Exp Pediatr. 2002;45(1):64-71.   Published online January 15, 2002
Purpose : This study was undertaken to review the clinical and hematologic findings of the preterm infants delivered from pregnancy induced hypertension(PIH) mothers. Methods : The data were collected by reviewing the medical records on the current prognosis of preterm birth and sending questionnaires on the status of NICU. We reviewed the medical records from two university hospitals and two resident training hospitals in...
Relationship between Brain MRI and Neurodevelopmental Outcome in Term Infants with Severe Hypoxic Ischemic Encephalopathy
Sun Young Park, Kyoung Sim Kim, Sung Soo Rim, Byung Soon Kang, Eun Young Kim, Yong Wook Kim, Se Jong Kim
Clin Exp Pediatr. 2001;44(2):139-148.   Published online February 15, 2001
Purpose : We analyzed the relationship between MRI patterns and neurologic outcome and explored the effectiveness of MRI as a tool for predicting the outcome. Methods : We analyzed 23 full term infants with severe HIE retrospectively who were admitted to our NICU from Sep. 1993 to May 1998. Their MRI findings were classified into 4 patterns : type I :...
Case Report
Four Cases of Congenital Depressed Skull Fractures in Neonates
Byung Soon Kang, Eun Young Kim, Chang Weon Oh, Kyoung Sim Kim, Yong Wook Kim, Min Suk Oh
Clin Exp Pediatr. 2000;43(4):567-572.   Published online April 15, 2000
Depressed skull fractures in newborn babies mainly result from birth injury and rarely occurr in intrauterine life without any definable etiology. We present 4 cases of congenital intrauterine depressed skull fractures which were discovered at birth in neonates. Three babies(case 1, 2, 3) had round shallow depressions without adjacent soft tissue injury except the last one(case 4), showing sharp angulation...
Original Article
The Prognosis and Factors of Neonatal Thyroid Dysfunction
Yun Yee Kim, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 2000;43(1):23-33.   Published online January 15, 2000
Purpose : The function of the neonatal thyroid is affected transiently or consistently by various maternal thyroid diseases, neonatal diseases, drugs, and more as well as thyroid dysgenesis. In this study, we analyzed several factors of neonatal thyroid dysfunction through neonatal screening test and investigated the prognosis. Methods : From January 1992 to July 1997, we reviewed 66 newborn patients, who showed abnormal thyroid function...
Case Report
A Case of Cavernous Sinus Thrombosis due to a Mistreated Facial Furuncle
Chae Yun Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1999;42(4):584-588.   Published online April 15, 1999
Infections of the face, especially of the medial third or “the danger triangle”, are the most frequent primary foci associated with thrombosis of cavernous sinus. Microorganisms entering the facial vein and pterygoid plexus from these sites are easily carried to the sinus through the ophthalmic vein. When the septic thrombosis involves various structures in the sinus, multiple clinical manifestations develop...
Original Article
Prognosis of Bacterial Meningitis based on Cerebrospinal Fluid Culture
Yun Ju Lee, Won Sung Lee, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(5):614-621.   Published online May 15, 1998
Purpose : The present study was undertaken to assess whether the results of cerebrospinal fluid (CSF) culture are related to prognosis. Methods : Subjected to this study were 51 cases admitted to our department who had been diagnosed as bacterial meningitis. They were divided into two groups, Group Ⅰ(20) with positive CSF culture and Group Ⅱ(31) with negative outcome, then both...
Case Report
A Case of Berry Syndrome associated with Syndactyly
Sang Chun Jung, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(4):543-547.   Published online April 15, 1998
Berry syndrome is a rare association of congenital heart anomalies which consists of a distal aortopulmonary window with aortic origin of the right pulmonary artery and hypoplasia or interruption of the aortic arch. This defect can be corrected only by immediate surgical intervention, so accurate preoperative diagnosis and detailed anatomic depiction of this syndrome are important in prognosis. We experienced a case of Berry...
Original Article
The Pelvic Changes of Patients with Down Syndrome in Korea
Jong Park, Kwan Cheol Oh, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1997;40(2):159-166.   Published online February 15, 1997
Purpose : Since Caffey et al. first described the anomaly in pelvis among the Down patients, decreased iliac and pelvic indexes have been helpful in diagnosing the syndrome. For Korean cases, however, no definitive data are available as yet, prompting us to evaluate the pelvic changes in Korean Down's patients. Methods : Subjected to this study were 68 children with Down's syndrome. As...
Relationship between Complications of Mycoplasma Pneumonia and Titers of Cold Agglutinin and Mycoplasma Antibody in Children
Sung Soo Rim, Myung Hyun Cho, Byung Min Moon, Kyoung Sim Kim, Kibok Kim
Clin Exp Pediatr. 1996;39(12):1680-1689.   Published online December 15, 1996
Purpose : To assess the relationship between the complications of mycoplasma pneumonia and titers of cold agglutinin and mycoplasma antibody in children. Methods : 120 cases of mycoplasmal pneumonia in children who were admitted to the Pediatric Department of Kwangju Christian Hospital between June 1993 and May 1994 were analyzed. Results : 1) The peak incidence of age was between 2 and...
Trend of Tuberculous Meningitis since 1970
Jeong A Park, Chang Weon Oh, Kyoung Sim Kim, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1996;39(11):1527-1537.   Published online November 15, 1996
Purpose : The incidence of tuberculous meningitis has reportedly decreased from 4.2% in 1970 to 1.8% in 1990 in Korea; however, tuberculous meningitis, which spreads hematogenously, claiming majority of mortality in childhood tuberculosis, still poses serious problems. This study was performed to evaluate the recent trend of tuberculous meningitis. Methods : We compared with three groups of tuberculous meningitis, two were our previous reports on...
Evaluation of Chromosomal Analyses done on the Parents with Chromosomal Anomalous Children and Recurrent Abortion
Kyoung Sim Kim, Kibok Kim, Won Jin Kee
Clin Exp Pediatr. 1996;39(9):1216-1223.   Published online September 15, 1996
Purpose : To gather reference data for better genetic counseling, we have evaluated the outcomes of chromosomal analyses performed on the parents with chromosomal anomalous children and recurrent abortion in this hospital for the last 20 years. Methods : Subjected to study were 108 parents (50 fathers & 58 mothers) who had children with Down syndrome, other chromosomal and congenital anomalies, and those who...
Clinical Characteristics of Patients with Tumer' Syndrome according to Karyotypic Differences
Eun Young Kim, Kyoung Sim Kim, Kibok Kim, Won Jin Kee
Clin Exp Pediatr. 1995;38(11):1460-1469.   Published online November 15, 1995
Purpose : To assess the differences of clinical features according to various karyotypes in Turner syndrome. Methods : Subjected to study were 45 patients with Turner syndrome, including 5 newborns, from March 1974 to April 1994. They were divided into 3 groups according to karyotypes: 45,X, mosaicism, and structural aberration; and the clinical features were compared. Also structural aberration groups, 46,XXp-and...
Case Report
Arthrogryposis Multiplex Congenita in Siblings
Kyoung Hee Choi, Jeong Ah Park, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1995;38(9):1293-1298.   Published online September 15, 1995
Arthrogryposis multiplex congenita is a rare congenital disorder characterized by multiple fixed-joint deformities of the upper and lower extremities. Most cases are sporadic, although rare cases of familial recurrence are reported worldwide. Recently, we experienced 2 cases of arthrogryposis multiplex congenita in a family (a brother and a sister). They were born with micrognathia, low set ears, broad and short...
Erratum
Clinical Evaluation of Unmarried Maternal Neonates Admitted to NICU
Chang Weon Oh, Suk Hyun Lee, Kyoung Sim Kim, Ki Bok Kim
Accepted January 1, 1970  
Purpose : This study was done to see whether neonates born to unmarried mothers have higher rates of prematurity, low birth weight, perinatal morbidity and mortality than normal married group. Methods : 88 neonates of unmarried mothers who were admitted in our NICU during the 5-year period from January 1987 through December 1991 were evaluated, and as the control gro-up served...
Case Report
A Case of Acrodysostosis
Suk Hyun Lee, Chang Won Oh, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1995;38(1):133-137.   Published online January 15, 1995
Acrodysostosis is a rare multiple congenital malformation syndrome with peripheral dysostosis, nasal hypoplasia, mental retardation and growth failure. In 1968, Maroteaux and Malamut first described this disorder in three patients, and thus far now over 30 published cases have been reported worldwide. Radiographic changes include severe shortening of metacarpals, metatarsals, and phalages, cone-shaped epiphyses of the hands and feet, premature fusion...
Original Article
Normal Blood TSH, T4 Levels in Neonates as Determined by Screening Test
In Ah Cha, Kwang Sin Kim, Kyoung Sim Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(6):832-841.   Published online June 15, 1994
In 1,146 term neonates without perinatal problems who were born in kwangju Christian Hospital, blood TSH levels were measured by immunoradiometric assay. In 397 term neonates among them, blood T4 levels were measured by radioimmunoassay in same specimens. 1) In normal neonates aged 3~5days, 6~10days, 11~20days and 21~28days, the TSH levels were 8.885.21(meanSD), 9.44¡¾5.16, 9.69¡¾4.98, 11.963.75IU/ml and the T4 levels were...
A Clinical Study on Twins
Kwang Sin Kim, In Ah Cha, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1994;37(4):537-546.   Published online April 15, 1994
We observed 233 twins and 2 triplets cases among 16,774 newborns delivered at Kwangju Christian Hospital during 5 years from Jan. 1986 to Dec. 1990. The results obtained are as follows : 1) The overall incidence of twin pregnancy was 1 : 72 (1.4%) and that of triplets 1 : z8387 (0.01%). 2) The average male-female sex ratio of twins was 1.06 :...
Clinical Study on 44 Cases of Infant Born to Polyhydramniotic Mother
Byung Min Moon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1992;35(5):630-638.   Published online May 15, 1992
Forty four cases of Polyhydramnios were studied clinically among 13,337 newborn infants delivered in Kwangiu Christian Hospital during the period from April 1, 1986 through March 31, 1990. 1) The incidence of polyhydramnios was 0.33%. 2) The mean gestational age was 37.2 week, and 18 cases(40.8%)were premature, while 3 babies (6.8%) were born postmaturely. 3) The mean birth weight was 2.3kg, with 30...
The Incidence of Hypothyroidism in Children with Down Syndrome
Seong Hyeon Jeon, Chun Ho Cho, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1992;35(4):534-538.   Published online April 15, 1992
A review of Thyroid function tests was performed on 32 children with Down syndrome confirmed by cytogenetic examination at the Dept. of Pediatrics, Kwangju Christian Hospital from Jan.1989 to Feb.1990. 1) Twenty among 32 children with Down syndrome were male, with the sex ratio being 1.7 : 1. Their ages ranged from 3 days to 5 years, with the mean age...
A clinical study on goiter in childhood.
Yeong Hee Chung, Byung Min Moon, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(1):83-94.   Published online January 31, 1991
A clinical study was done on 96 cases of goiter in children which were diagnosed at pediatric department of Kwangju Christian Hospital during the period form January 1985 to December 1988. The observed clinical data were summarized as follows: 1) Preponderately femalels were affected with the sex ratio of 1:6.7. The majority of cases (78.2%) were around puberty. 2) On physical examination, 59 cases (85.5%) were found...
Clinical Study of Intussusception in Childhood Comparison Between Barium Reduction Group and Surgically Treated Group.
Seung Hyun Cheon, Kyoung Sim Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1989;32(5):630-637.   Published online May 31, 1989
A clinical study was undertaken on 172 cases of intussusception who had been admitted to Kwangju Christian Hospital from Jan. 1981 to June 1987. 110 cases were treated by barium reduction, were analyzed and were compared with 62 cases treated surgically. The results were as followed; 1) In age incidence, 88.2% of barium reduction group (BRG) and 85.5% of surgically treated group (STG) were...
Influences of Premature Rupture of Membranes on the Newborn Infant.
Kyoung Sim Kim, Young Ok Park, In Sung Lee, Ki Bok Kim
Clin Exp Pediatr. 1989;32(2):149-157.   Published online February 28, 1989
A comparative study on the frequencies of premature birth, neonatal sepsis, asphyxia, perinatal death and respiratory distress syndrome was carried out between 1309 newborns with premature rupture of membranes (PROM) and the normal group of 4636 newborns without PROM among all 5945 babies delivered at Kwangju Christian Hospital for the 2-year period starting from March 1985. The results are sumrnarized as follows: 1) The overall...
Physical Features, Karyotypes and Dermatoglyphics of 113 Children with Down Syndrome.
Byung Ho Lim, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1988;31(4):474-481.   Published online April 30, 1988
The physical features including dermatoglyphic patterns as well as the karyotype patterns were assesed in 113 children with Down Syndrome who had been cytogenetically confirmed in the Department during past 5 years from August 1981. The results are summarized as follows: 1) The sex ratio of the patients was 1.2 male to one female. 2) Cytogenetic examination revealed 21-trisomy in 79% and translocation in 21% of all...