Clinical and Experimental Pediatrics

Original Article

Infection

Carbapenem resistance in gram-negative pathogens in an Iranian hospital: high prevalence of OXA-type carbapenemase genes

Setareh Mamishi, Reihaneh Hosseinpour Sadeghi, Sadaf Sajedi Moghaddam, Babak Pourakbari, Shiva Poormohammadi, Maryam Sotoudeh Anvari, Shima Mahmoudi

Clin Exp Pediatr. 2025;68(1):65-72. Published online October 31, 2024

Question: What is the prevalence of carbapenem resistance in gram-negative bacteria and associated carbapenemase genes?
Findings: This study identified a notable prevalence of carbapenem-resistant gram-negative isolates, with Escherichia coli being the predominant contributor, follow ed by Klebsiella pneumoniae, Acinetobacter baumannii, while bla _OXA48 was the most prevalent carbapenemase gene.
Meaning: These findings highlight the urgent need for proactive measures including the rapid detection of carbapenemase- producing isolates and effective infection control.

DOI: https://doi.org/10.3345/cep.2023.01774

Full text
PubReader
ePub
PDF

Cited By 18	Long COVID in children and adolescents: prevalence, clinical manifestations, and management strategies
Cited By 17	Neurodevelopmental outcomes of preterm infants
Cited By 14	Gut microbiota affects brain development and behavior
Cited By 13	Association of gut microbiota with obesity in children and adolescents
Cited By 12	Korean Developmental Screening Test for Infants and Children (K-DST): development, applications, and implications for future early childhood development interventions

Search