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Original Article
The usefulness of soluble transferrin receptor in the diagnosis and treatment of iron deficiency anemia in children
Se Hoon Yoon, Dong Sup Kim, Seung Taek Yu, Sae Ron Shin, Du Young Choi
Clin Exp Pediatr. 2015;58(1):15-19.   Published online January 31, 2015
Purpose

Soluble transferrin receptor (sTfR) is a truncated extracellular form of the membrane transferrin receptor produced by proteolysis. Concentrations of serum sTfR are related to iron status and erythropoiesis in the body. We investigated whether serum sTfR levels can aid in diagnosis and treatment of iron deficiency anemia (IDA) in children.

Methods

Ninety-eight patients with IDA were enrolled and were classified according to...

Relationship between iron deficiency anemia and febrile convulsion in infants
Youn Soo Jun, Ho Il Bang, Seung Taek Yu, Sae Ron Shin, Du Young Choi
Clin Exp Pediatr. 2010;53(3):392-396.   Published online March 15, 2010
Purpose : The association between iron deficiency anemia and febrile convulsion in infants has been examined in several studies with conflicting results. Therefore, the authors aimed to evaluate the precise relationship involved. Methods : In this case-control study, the authors assessed 100 children with a diagnosis of febrile convulsion, aged between 9 months and 2 years, during January 2007 to...
Anti-tumor effect of new compound, 127, through the induction of apoptosis
Ki Hwan Baek, A Lum Han, Sae Ron Shin, Chun Mae Jin, Young Wook Yoon, Seung Taek Yu, Jong Duk Kim, Du Young Choi
Clin Exp Pediatr. 2009;52(6):696-700.   Published online June 15, 2009
Purpose : We screened more than 350 compounds with an endoperoxide ring structure in search of an anti-leukemic drug and found that compound 127 (c-127) could induce significant cytotoxicity in HL-60 cells. In this study, we investigated the molecular mechanisms of compound 127-induced antitumor activity on HL-60 cells. Methods : HL-60 cells were cultured in Rosewell Park Memorial Institute 1640...
Clinical features of vaccination-associated thrombocytopenic purpura in children
Wan Soo Lee, Seung Taek Yu, Sae Ron Shin, Du Young Choi
Clin Exp Pediatr. 2008;51(6):610-615.   Published online June 15, 2008
Purpose : Idiopathic thrombocytopenic purpura (ITP) is a relatively common hematological disease in children. It generally occurs after exposure to a common viral infection episode; however, it may occasionally follow immunization with measles, measles-mumps-rubella (MMR), hepatitis B (HBV), influenza, diphtheria tetanus-pertussis (DTP), or chickenpox vaccines. In this study, the incidence, clinical characteristics, and treatment outcome of vaccination-associated ITP were investigated...
Study on the Correlation between Clinical Classification according to Hemorrhagic Symptoms and Platelet Counts in Childhood Idiopathic Thrombocytopenic Purpura
Ho Il Bang, Sae Ron Shin, Du Young Choi
Clin Exp Pediatr. 2004;47(4):412-416.   Published online April 15, 2004
Purpose : Idiopathic thrombocytopenic purpura(ITP) is a relatively common hematologic disease in children. The optimal strategy for treating ITP during childhood is a matter of controversy. In general, platelet count has been the primary, if not the sole measure, on which treatment decisions have been made and outcomes determined. In this study, we tried to find out the correlation between...