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Original Article
Nutrition
Increment in vitamin D level and bone mineral accrual in children with vitamin D deficiency
Yashwant Kumar Rao, Tanu Midha, Satyajeet Singh, Anurag Bajpai, Amita Tilak
Clin Exp Pediatr. 2016;59(7):292-297.   Published online July 31, 2016
Purpose

To compare different regimens of vitamin D with respect to its serum increment levels and bone mineral accrual in vitamin D-deficient children.

Methods

Children identified as being vitamin D deficient (serum levels<20 ng/mL) were divided into 3 treatment groups by stratified block randomization (group 1, 4,000 IU/day of vitamin D3 plus 50 mg/kg/day calcium for 12 weeks; group 2, 30,000 IU/wk of...

Case Report
Autosomal dominant hypocalcemia with Bartter syndrome due to a novel activating mutation of calcium sensing receptor, Y829C
Keun Hee Choi, Choong Ho Shin, Sei Won Yang, Hae Il Cheong
Clin Exp Pediatr. 2015;58(4):148-153.   Published online April 22, 2015

The calcium sensing receptor (CaSR) plays an important role in calcium homeostasis. Activating mutations of CaSR cause autosomal dominant hypocalcemia by affecting parathyroid hormone secretion in parathyroid gland and calcium resorption in kidney. They can also cause a type 5 Bartter syndrome by inhibiting the apical potassium channel in the thick ascending limb of the loop of Henle in the...

Two Cases of Inhalation Injury Caused by An Explosion of Two Different Chemical Disinfectants(Sodium Dichloroiso Cyanurate & Calcium Hypochlorite) in a Swimming Pool
Su Jin Lee, Eun Young Park, Mi Ran Kim, Kon Hee Lee, Kwang Nam Kim
Clin Exp Pediatr. 2003;46(2):198-202.   Published online February 15, 2003
Of all toxic inhalant exposures, chlorine is one of the most common toxic chemical inhalants. When acutely inhaled, it can be responsible for symptoms ranging from upper air way irritation to more serious respiratory effects. It can also deteriorate lung function and lead to death. Chlorine and its compounds such as chlorinated cyanurates and hypochlorites are commonly used in water...
Original Article
Identification of a Calcium-activated Potassium Channel Gene Expressed in Rat Cardiac Myocytes
In Seung Park, Hyun-Kyu Jeon, Nam Su Kim, Youn Mo Ahn, Chul-Seung Park, Ha Baik
Clin Exp Pediatr. 2000;43(7):905-912.   Published online July 15, 2000
Purpose : Calcium-activated potassium channels(KCa) may be involved in the transient outward current of the first phase of cardiac action potential. But it is still not clear whether cardiac myocytes express any KCa. We try to identify here the types of KCa expressed in rat caridac myocytes. Methods : We isolated total heart RNA from 50 rats(Spague-Dawley) and performed reverse transcription-polymerase chain reaction(RT-PCR) using specifically...
Therapeutic Effect of Nimodipine in Neonatal Rat Model of Cerebral Hypoxia-Ischemia
Ihn-Hee Hong, Heng-Mi Kim
Clin Exp Pediatr. 1999;42(11):1552-1558.   Published online November 15, 1999
Purpose : Recent studies suggest that nimodipine, a potent calcium-channel blocker, may improve neurological outcome after experimental hypoxia-ischemic brain injury. This study was conducted to evaluate the therapeutic effect of nimodipine on hypoxia-ischemia in immature rat brain. Methods : Seven-day postnatal rats were subjected to hypoxia-ischemia by unilateral common carotid artery occlusion combined with 2 hours of hypoxia(in 8% oxygen...
Erratum
Reference Values of Hematologic and Biochemical Parameters of Nutrition around Weaning Period
Seung Joo Lee, Jeong Wan Seo, Jae Ock Park, Jae Hoon Shin, Hae Ran Lee, Ji Tae Chung, Hae Il Chung
Clin Exp Pediatr. 1999;42(1):6-14.   Published online January 15, 1999
Purpose : To determine the reference values of hematologic and biochemical parameters of nutrition around the weaning period. Methods : From February 1996 to March 1997, several nutritional laboratory values were evaluated in 130 healthy babies and 120 inpatients in the recovery stage of acute illness at six general hospitals. Results : Reference values in 9-month-old healthy babies(range : 6-12 months) were...
Original Article
Random Urine Ca/Cr Ratio in Healthy Neonates
Hea Young Lee, So Young Park, Eun Sun Yoo, Eun Ae Park, Seung Joo Lee
Clin Exp Pediatr. 1998;41(3):378-382.   Published online March 15, 1998
Purpose : Recently, in high risk preterm infants, we experienced high incidence of hypercalciuria, nephrolithiasis & nephrocalcinosis. To screen hypercalciuria, we need the normal value of random urine Ca/Cr ratio in healthy neonates according to gestational age, postnatal age, milk and calcium intake. Methods : Random urine Ca/Cr ratio was checked in 260 healthy full-term infants at the 2-7th day, and...
Hypercalciuria in High Risk Neonate
Eun Sun Kim, Seung Joo Lee
Clin Exp Pediatr. 1994;37(3):322-331.   Published online March 15, 1994
The incidence and risk factors for hypercalciuria were studied in 23 sick preterm (Group I), 36 well preterm (Group II), 16 sick term (Group III) and 41 well term (Group IV) neonates who were admitted to NICU and nursery of Whwa Woman's University Hospital from May 1988 to February 1992. The results were as follows: 1) The incidences of hypercalciuria were 73.9%...
A Study of Calcium and Inorganic Phosphorus Levels in Maternal and Cord Blood
Woo Ha You, Seung Wan Lee, Jong Lin Rhi, Hyun Joo Jeong, Yong Joon Shin, Chung Hak Park
Clin Exp Pediatr. 1992;35(4):492-498.   Published online April 15, 1992
A study of serum calcium, phosphorus levels in mother and umbilical cord was carried on 39 mother/baby pairs who were admitted to DAE HAN Hospital from Nov.1989 through Feb.1990. The results abstained were as follows: 1) The mean serum calcium levels of maternal and cord blood were 8.92¡¾10.59mg% and 9. 88¡¾10.74mg% repectively. The mean serum calcium of cord blood was statiscally higher than...
Sodium and calcium transport in spherocytic red blood cells.
Shin Heh Kang, Kir Young Kim, Young Ho Lee, Bok Soon Kang
Clin Exp Pediatr. 1991;34(7):978-991.   Published online July 31, 1991
Hereditary spherocytosis (HS) is an autosomal, dominantly inherited hemolytic disorder which shows characteristic spherocytes on peripheral smear. As spherocytes are rounder, more fragile and susceptible to extravascular hemolysis in the spleen, HS patients suffer from variable degrees of anemia, jaundice, splenomegaly and gall stones. However the pathogenesis is heterogenous in HS, such as spectrin deficiency, decreased spectrin-protein 4.1 binding, increased spectrin binding to the RBC...
A study on Serum Calcium, Phosphorus, Magnesium and Parathyroid Hormone Levels of Cord Blood in Newborn.
Kwang Rhun Koo, Chang Soo Ra
Clin Exp Pediatr. 1986;29(2):163-169.   Published online February 28, 1986
A study of serum calcium, magnesium, phosphorus and PTH levels of cord blood in newborn infants and those of serum levels of maternal blood at parturition was carried on 38 mother/baby pairs who were admitted to Chosun University Hospital from November, 1982 throgh Desember, 1982. The following results were obtained; 1) The serum calcium levels of cord blood in 38 cases of the...
Calcium, Phosphorus, and Magnesium contents of Breast Milk.
In Bock Lee, Kwang Rhun Koo, Chang Soo Ra
Clin Exp Pediatr. 1985;28(12):1216-1220.   Published online December 31, 1985
In order to determine the concentration of Ca, P, and Mg of breast mik and the alterations of their concentrations during the period of lactation, the authors studied the concentrations of Ca, P, and Mg of breast milk from 68 Korean healthy nursing mothers who delivered at term. Ca, P, and Mg concentration of breast milk were measured by calorimetric...
A Study on Calcium Metabolism in Newborn Infants.
Jin Heon Kim, Chang Soo Ra
Clin Exp Pediatr. 1985;28(10):967-976.   Published online October 31, 1985
A thorough understanding of calcium homeostasis and metabolism in newborn infants is necessary in the evaluation of any newborn infant with hypocalcemia. Author studied the levels of urinary calcium and phosphorus during the 48 hours after birth, and also studied before and after feeding during the 24 hours after birth in 19 normal term infants. And serum calcium, phosphorus, parathormone,...
The Influence of Phototherapy on the Concentration of Serum Calcium.
Hyun Sook Lee, Hung Bae Park
Clin Exp Pediatr. 1984;27(9):865-871.   Published online September 30, 1984
Since the report of Dr. Cremer in the 1950s the effectiveness of phototherapy in the treatment of neonatal hyperbilirubinemia has been demonstrated in many clinical trials and now become widely accepted as a routine therapeutic measure in most pediatric clinics. Considering the relatively high incidence of prematurity and neonatal jaundice especially in Asian countries, it is of great concern to...
A Study of Calcium and Inorganic Phosphorus Levels in Umbilical Cord Blood.
Woo Yoeng Chung
Clin Exp Pediatr. 1983;26(9):850-856.   Published online September 30, 1983
The levels of serum calcium and inorganic phosphorus were studied in 50 pairs of umbilical cord and maternal blood at parturition and further more I try to compare statistically with each other. The reuslts obtained were summarized as follows: 1) The mean serum calcium levels of cord and maternal blood were 10.52±0.81 mg% and 9.23±1.16 mg% respectively. The mean serum calcium level of...
Serum level of Calcium and Phosphorus in Normal Infants.
Sung Won Park
Clin Exp Pediatr. 1981;24(3):209-215.   Published online March 15, 1981
The levels of calcium and phosphorus in serum were measured during the first 6 months of life in 112 normal infants to find out normal values of them. The total subjects were devided into 6 subgroups by age. The results? obtained 1.During 1 〜2 weeks of life, the average level of serum calcium is 4. 92±0. 33 mEq/L^phosphoruSi 7. 32±0.42...