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Original Article

Expression of Fibroblast Growth Factor Receptors at Different Stages of Differentiation in Chick Embryo Chondrocytes

Jo Young Suh, Jong Eul Park, Woo Taek Kim

Clin Exp Pediatr. 2004;47(4):439-447. Published online April 15, 2004

Purpose : Proliferative chondrocytes and prehypertrophic chondrocytes secrete significant amounts of type II collagen in an extracellular matrix. In contrast, hypertrophic chondrocytes secrete type X collagen. In addition, fibroblast growth factors (FGFs) and fibroblast growth factor receptors (FGFRs) also appear to play an important role during differentiation. Accordingly, the current study identified and characterized the chondrocytes and FGFR mRNA expressed...

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