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Original Article
Neurology
Comparison of conservative therapy and steroid therapy for Bell’s palsy in children
Hye Won Yoo, Lira Yoon, Hye Young Kim, Min Jung Kwak, Kyung Hee Park, Mi Hye Bae, Yunjin Lee, Sang Ook Nam, Young Mi Kim
Clin Exp Pediatr. 2018;61(10):332-337.   Published online September 12, 2018

Purpose: Bell’s palsy is characterized by sudden onset of unilateral facial weakness. The use of corticosteroids for childhood Bell’s palsy is controversial. This study aimed to identify clinical characteristics, etiology, and laboratory findings in childhood Bell’s palsy, and to evaluate the efficacy of corticosteroid treatment. Methods: We conducted a retrospective analysis of children under 19 years of age treated for Bell’s...
Case Report
Facial palsy as the presenting symptom of acute myeloid leukemia in children: Three cases with stem cell transplantatio
Hee Jo Baek, Dong Kyun Han, Young Ok Kim, Ic Sun Choi, Tai Ju Hwang, Hoon Kook
Clin Exp Pediatr. 2009;52(6):713-716.   Published online June 15, 2009
Facial palsy as the presenting symptom of leukemia is very rare, especially in acute myeloid leukemia. A review of the medical literature identified reports on 8 children with AML who had facial paralysis as the presenting sign. Whole brain irradiation (WBI) has been applied in most cases. We present the cases of 3 such children. Achieving a remission without WBI,...
A case of mosaic ring chromosome 13 syndrome
Soo Young Kim, Soo Min O, Mi Jeong Kim, Eun Song Song, Young Ok Kim, Young Youn Choi, Young Jong Woo, Tai Ju Hwang
Clin Exp Pediatr. 2009;52(2):242-246.   Published online February 15, 2009
The clinical features of ring chromosome 13 include mental and growth retardation, CNS anomalies, facial dysmorphism, cardiac defects, genital malformations, limb anomalies, skeletal deformities and anal malformations. Although many cases of ring chromosome 13 have been reported worldwide, only 6 cases have been reported in Korea, and the latter cases were not mosaic but pure ring chromosome 13. Here we...
Original Article
Effects of enucleation and chemotherapy in advanced intraocular and intraorbital retinoblastoma with or without radiotherapy
Jae Min Lee, Hyun Dong Lee, Jeong Ok Hah
Clin Exp Pediatr. 2008;51(1):84-88.   Published online January 15, 2008
Purpose : Radiotherapy is effective in local treatment for retinoblastoma. However, asymmetric facial hypoplasia after radiation is a serious late effect. This study was performed to investigate the effects of enucleation and chemotherapy with or without radiotherapy in advanced intraocular and intraorbital retinoblastoma. Methods : Between 1985 October and 2006 December, the records of thirty five patients who were diagnosed as...
Case Report
Costello syndrome: three sporadic cases
Ji Youn Kim, Mi Jeong Kim, Eun Song Song, Young Kuk Cho, Young Youn Choi, Jae Sook Ma
Clin Exp Pediatr. 2007;50(10):1024-1029.   Published online October 15, 2007
Costello syndrome (CS) is a rare multiple congenital abnormality syndrome characterized by a typical coarse face, developmental delay, psychomotor and growth retardation, neurologic abnormalities, cardiac and cutaneous anomalies, severe feeding difficulties with postnatal growth failure, and increased risk of tumors. Since Costello first described it in 1971 and again in 1977, over 100 cases have been reported worldwide. It was...
A Case of Trisomy 9 Mosaicism
Young Ok Kim, Chun Hak Park, Ic Sun Choi, Hyun Jung Kim, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2003;46(6):597-601.   Published online June 15, 2003
Trisomy 9 mosaic syndrome is a rarely reported chromosomal abnormality with high incidence of intrauterine growth retardation and perinatal death. Even a baby lives, he has severe mental retardation and significant malformations. The incidence and severity of malformations and mental retardation correlate with the percentage of trisomic cells in the different tissues. The characteristic craniofacial abnormalitis are narrow bifrontal diameter,...
A Case of Raine Syndrome
Hye Jin Park, Jeong Jin Lee, Jeong Sik Seo, Hyo Jin Kim, Je Yong Choi, Jun Hwa Lee, Un Seok Nho, Hai Lee Chung, Woo Taek Kim
Clin Exp Pediatr. 2003;46(1):91-94.   Published online January 15, 2003
Raine syndrome was described as an unknown syndrome in 1989. It is characterized by severe craniofacial anomalies with microcephaly, hypoplastic nose, depressed nasal bridge, exophthamos/protosis, gum hypertrophy, cleft palate, low-set ears, small mandible, narrow chest, wide cranial sutures and choanal atresia or stenosis, by generalized osteosclerosis with subperiosteal thickening of ribs, clavicles and diaphysis of long bones, and by intracranial...
A Case of Ramsay-Hunt Syndrome
Ok Ja Jeong, Se Wook Oh, Se Chang Ham, Yong Won Park
Clin Exp Pediatr. 2000;43(12):1608-1612.   Published online December 15, 2000
Ramsay Hunt Syndrome was initially described by Ramsay Hunt in 1907 as herpes zoster of the geniculate ganglion. The frequency of RHS in patients with herpes zoster has been calculated to be about 1%. RHS affects mostly adults; however a small number of children with herpes zoster oticus have been reported. We describe a case of RHS in a healthy...
Original Article
Immunologic Characteristics of CATCH 22 Syndrome
Hye Young Ryu, Eun Kyung Jo, Eun Jung Cheon, Hong Ryang Kil, Jae Ho Lee
Clin Exp Pediatr. 2000;43(11):1423-1429.   Published online November 15, 2000
Purpose : Microdeletion of chromosome 22q11.2 are associated with DiGeorge syndrome(DGS), velocardiofacial syndrome(VCFS) and conotruncal anomaly face syndrome(CTAFS). DGS was originally described as an immunodeficiency disorder secondary to impaired T cell production due to thymic aplasia or hypoplasia. But the frequency & severity of immunodeficiency of other clinical syndromes associated with the chromosome 22q11 deletion has not been investigated. This...
Neonatal Facial and Cry Responses to Invasive and Non-invasive Procedures
Seon Hwa Seo, Young Pyo Chang
Clin Exp Pediatr. 1997;40(11):1520-1528.   Published online November 15, 1997
Purpose : The evaluation of pain in neonates is difficult due to their limited means of communication. The aim of this study was to determine whether the behavioral reactions of facial action and cry provoked by an invasive pain-induced procedure could be discriminated from the reactions to a noninvasive pain-induced procedure in normal full-term neonates. Methods : Thirty-six healthy full-term neonates received three pain-induced...
Case Report
A Case of Roberts Syndrome
Young Choi, Yo Han Chung, In Seok Lim, Chul Ha Kim, Dong Keun Lee, Seong Nam Kim, Sang Yong Song, Je Geun Chi
Clin Exp Pediatr. 1993;36(10):1447-1451.   Published online October 15, 1993
Roberts syndrome is an autosomal recessive disorder accompanied by limb defects, craniofacial abnormalities, pre-and postnatal growth retardation. Patients with Roberts syndrome have characteristic premature separation of heterochromatin of many chromosomes and abnormalties in celldivision cycle. We have experienced a case of Roberts syndrome in an immature neonate. The patients showed characteristic clinical features of multiple encephaloceles. Severe facial mid-line clefts, and...
A Case of Infectious Mononucleosis Associated with Facial Nerve Palsy
Ho-Suk Lee, Jin-Park , Il-Soo Kim, Sung-Ho Cha, Byoung-Soo Cho, Chang-Il Ahn
Clin Exp Pediatr. 1993;36(4):579-582.   Published online April 15, 1993
Infectious Mononucleosis is a common sysemic illness primarily invloving children and young adults and due apparently to the Epstein-Barr virus (EBV). Although the typical case is easily recogniged, unusual manifestations or serious complications occur frequently enough to pose problems in diagnosis and management. Neurologic complications are rare(1%). These nerologic complications may actually precede the full clinical picture or presen: as the sole...
Original Article
Case of Craniofacial Dysostosis(Crouzon's disease).
Seung Hyun Cheon, Ju Hwi Kim, Young Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1989;32(4):576-581.   Published online April 30, 1989
We experienced a case of Crouzon’s disease in a female neonate with chief complaints of respira- tory distress and bilateral exophthalmos with corneal opacity. Physical examination revealed craniosynostosis, bilateral exophthalmos, external strabismus, parrot beaked nose, high arched palate, hypoplasia of maxilla, prognathism of mandible, protruded tongue and adducted flexion deformity of both arms. A brief review of literatue was made.
Case Report
A Case of Craniofacial Dysostosis(Crouzon's Disease).
Song Tae Kim, Yong Sang Yoo, Yong Youun Choi
Clin Exp Pediatr. 1985;28(10):1027-1031.   Published online October 31, 1985
We experienced a case of Crouzon* s disease in a 11 year 8 month-old boy with chief complaints of facial deformities and progressive impairment of visual acuity. Physical examination showed craniosynostosis, bilateral exophthalmos, external strabismus, birdlike beaked nose, high-arched palate, hypoplasia of maxilla, prognathism of mandible and dental malocclusion. The review of the literature was made briefly.
Original Article
A Clinical Study on Cardiofacial Syndrome (Asymmetric Cry Syndrome).
Chung Il Noh, Chang Yee Hong
Clin Exp Pediatr. 1985;28(7):637-641.   Published online July 31, 1985
Seven patients with cardiofacial syndrome were observed for twenty months from Oct. 1983 to May. 1985 at the Pediatric Department of Seoul National University. Age ranged from 1 months to 10 years and six patients were male. Right-sided facial palsy occurred in 4 patients and left-sided in 3 patients. Cardiac defects were TOF, VSD(membranous), Criss-Cross heart with large VSD, pulmonary...
Facial and Submandibular Cellulitis due to Staphylococcus Aureus.
Young Suk Song, Moon Ho Chung, Gwi Jong Choi, Soo Jee Moon, Chong Moo Park
Clin Exp Pediatr. 1983;26(7):663-666.   Published online July 31, 1983
A retrospective study was done on 20 cases of facial and submandibular cellulitis, who had been admitted to our institution from August 1978 to August 1982. The following results were obtained. 1) There were no differences in sexual incidence. 2) In age incidence, 14 cases(70%) were before 2 years old. 3) The most frequent site of facial and submandibular cellulitis was left submandibular area, which was 11...
Case Report
A Case of 18p- Syndrome.
Jin Tae Kim, Byoung Soo Cho, Chang Hyo Lee, Chang Il Ahn, Kap Soon Ju
Clin Exp Pediatr. 1981;24(6):589-591.   Published online June 15, 1981
We have experienced a case of 18p- syndrome in 22 month old girl who had craniofacial anomaly such as microcephaly, hypertelorism, nystagmus, depressed nasal bridge, complete bilateral cleft palate, both ear canal stenosis and mental retardation. Chromosome culture revealed short arm deletion of chromosome 18 in E group. As far as we know, this case is the first report of...
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