Clinical and Experimental Pediatrics

Review Article

Rheumatology

Double-negative T cells in pediatric rheumatic diseases

Dimitri Poddighe, Tilektes Maulenkul, Kuanysh Dossybayeva, Gulsamal Zhubanova, Zaure Mukusheva, Lyudmila Akhmaltdinova

Clin Exp Pediatr. 2024;67(12):632-640. Published online September 12, 2024

Double-negative T (DNT) cells appear to be increased in several pediatric rheumatic diseases and this finding may be correlated with disease activity to some extent. However, due to significant heterogeneity in several methodological aspects, further investigations in rheumatic children are needed to assess the potential relevance of DNT cells as biomarkers and clarify their immunopathological role.

DOI: https://doi.org/10.3345/cep.2023.01760

Original Article

CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia

Ji Eun Kim, Siegfried Bauer, Kyong Suk La, Kee Hyoung Lee, Ji Tae Choung, Kyoung Ho Roh, Chang Kyu Lee, Young Yoo

Clin Exp Pediatr. 2011;54(5):207-211. Published online May 31, 2011

Crossref 14

Purpose

This study was conducted to investigate the immune responses of children with moderate and severe novel influenza A virus (H1N1) pneumonia, and to compare their clinical and immunological findings with those of control subjects.

Methods

Thirty-two admitted patients with H1N1 pneumonia were enrolled in the study. The clinical profiles, humoral and cell-mediated immune responses of the 16 H1N1 pneumonia patients who were...

DOI: https://doi.org/10.3345/kjp.2011.54.5.207

Immunologic Changes of Peripheral Blood Lymphocytes in Kawasaki Disease after Intravenous Gamma Globulin Therapy

Jung Yeon Shim, Kyung Mo Kim, Young Hwue Kim, Soo-Jong Hong

Clin Exp Pediatr. 1996;39(5):712-721. Published online May 15, 1996

Purpose : Kawasaki disease(KD) is multi-systemic vasculitis and coronary artery abnormalities can develop up to 30 percent in untreated patients. Several observations suggest that immune activation and the secretion of cytokines from immune effector cells contribute to the pathogenesis of this disease. Though high dose intravenous gamma globulin(IVGG,>1 gm/kg) is effective in reducing the prevalence of coronary artery aneurysms in KD,...

PDF

Identification of Human Mononuclear Cell Population by Acid alpha-Naphthyl Acetate Esterase Staining.

S G Lee, B H Choi, K Ch Han, T H Chung

Clin Exp Pediatr. 1982;25(6):547-553. Published online June 30, 1982

This study was carried out to determine the clinical usage of acid alpha-naphthyl acetate esterase staining technic to define subpopulation of human peripheral blood lymphocytes and monocytes. 18 samples of peripheral blood smear of normal subjects were fixed in the formalin-aceton buffer fixative an stained by alpha-naphthyl acetate esterase techinc to be differentiated into 3 types of mononuclear cells; granular,...

PDF

Cited By 21	Neurodevelopmental outcomes of preterm infants
Cited By 19	Long COVID in children and adolescents: prevalence, clinical manifestations, and management strategies
Cited By 17	Association of gut microbiota with obesity in children and adolescents
Cited By 16	Nonalcoholic fatty liver disease and insulin resistance in children
Cited By 16	Prevalence of anxiety, depression, and stress among parents of neonates admitted to neonatal intensive care unit: a systematic review and meta-analysis

Search