Clinical and Experimental Pediatrics

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Original Article

Two cases of islet cell hyperplasia with nesidioblastosis.

Myeong Ku Cho, Kyeong Bae Park, Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee, D.H Lee

Clin Exp Pediatr. 1991;34(2):273-280. Published online February 28, 1991

Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose...

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