Clinical and Experimental Pediatrics

Original Article

Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants

Hwa Young Jang, Haeng Mi Kim

Clin Exp Pediatr. 1996;39(4):475-481. Published online April 15, 1996

Purpose : This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. Methods : For a total of ten VLBW infants who had...

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Effect of IVIG Treatment on Renal Function in Neonates

So Yeon Kim, Haeng Mi Kim

Clin Exp Pediatr. 1994;37(10):1414-1419. Published online October 15, 1994

This study was conducted to evaluate the effect of intraveneous immunoglobulin(IVIG) infusion on renal function in neonates. IVIG has provided quite safe in neonates given therapeutic doses. But nephrotoxicity is not a recognized adverse events of IVIG therapy, only several previous adult cases having been described. A total twenty five neonates suspected sepsis was randomely assigned to IVIG(n=12) or control(n=13) group. Neonates...

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Intravenous Immunoglobulin for Prophylaxis of Neoneatal Sepsis in the Premature Infants

K.H. Hur, S.H. Kim, H.S. Kim, M.J. Chey, K.H. Kim, H.S. Lee

Clin Exp Pediatr. 1993;36(11):1534-1541. Published online November 15, 1993

Newborn premature babies have low levels of transplacentally acquired maternal immunoglobulin which is mostly transferred after 32∼34weeks gestation, therefore they may have IgG deficiencies that incerase their susceptibillity to bacterial infection. We preformed this study to determine whether intravenous immunoglobulin (IVIG) therapy improves mortality or infection occurrence rate. From 1 october 1991 to 31 july 1992, 73premature newborn iffants with gestational age≤34weeks...

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An Experience of High Dose Intravenous Immunoglobulin Therapy in Refractory Evans Syndrome.

Hee Sup Kim, Won Sup Shin, Sang Il Lee, Sang Woo Kim

Clin Exp Pediatr. 1990;33(5):701-707. Published online May 31, 1990

Evans syndrome, a combination of autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura, relapses freguently and is refractory to conventional treatment such as corticosteroid, immunosuppressive agents, splenectomy and plasma exchange. Recently Oda et al applied high dose immunoglobulin (400/kg/day for 4 days repeated 2 weeks later) to 5 month-old infant with refractory Evans syndrome, and was successful in maintaining remission for five years and nine...

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