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Original Article
Clinical characteristics and outcomes of status epilepticus as an initial seizure in children
Mi Jeong Kim, Young Ok Kim, Sun Hee Kim, Woo Yeon Choi, Hyung Suk Byun, Chan Jong Kim, Young Jong Woo
Clin Exp Pediatr. 2006;49(6):659-664.   Published online June 15, 2006
Purpose : To evaluate the morbidity and mortality of children with status epilepticus(SE) as an initial seizure and to compare these according to age groups. Methods : The 78 cases(38 cases <2 years and 38 cases ≥2 years) with SE as an initial seizure admitted to the Chonnam national university hospital from Jan. 2000 to Jan. 2004 were reviewed. Developmental profiles,...
Review Article
Early recognition of high risk factors of acute abdominal pain in children
Jin-Bok Hwang
Clin Exp Pediatr. 2006;49(2):117-128.   Published online February 15, 2006
Non-traumatic acute abdominal pain in children presents a diagnostic dilemma. Numerous disorders can cause abdominal pain. Although many etiologies are benign, some require a rapid diagnosis and treatment in order to minimize morbidity. This review concentrates on the clinical office evaluation of acute abdominal pain in infants and children and details the clinical guideline for the diagnostic approach to imaging...
Original Article
Clinical Outcome and Prognostic Factors of Acute Respiratory Distress Syndrome in Children
Jung-Min Ko, Eun-Ju Ha, Eun-Hee Lee, So-Youn Lee, Hyo-Bin Kim, Soo-Jong Hong, Seong-Jong Park
Clin Exp Pediatr. 2005;48(6):599-605.   Published online June 15, 2005
Purpose : The purpose of this study was to examine the causes, clinical courses and outcomes in children with acute respiratory distress syndrome(ARDS), and evaluate the physiologic variables as prognostic factors in the patients. Methods : Retrograde medical chart review was carried out in 24 patients who were diagnosed with ARDS at the pediatric intensive care unit(PICU) during 20-month period. Results...
Statistical Analysis of 1,000 Cases of Kawasaki Disease Patients Diagnosed at a Single Institute
Dae Hwan Hwang, Kyoung Mi Sin, Kyong Min Choi, Jae Young Choi, Jun Hee Sul, Dong Soo Kim
Clin Exp Pediatr. 2005;48(4):416-424.   Published online April 15, 2005
Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients. Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed...
Surfactant Therapy for Neonatal Respiratory Distress Syndrome : Experience in Korea Over 15 Years
Chong-Woo Bae, Young-Min Kim
Clin Exp Pediatr. 2004;47(9):940-948.   Published online September 15, 2004
Purpose : Surfactant replacement therapy in neonates with respiratory distress syndrome(RDS) has been used in Korea since 1990. We undertook a collective study of trials from multi-hospitals to evaluate results of neonates with RDS who were treated with surfactant during the past 15 years in Korea(Period I, P-I, 1990-91; Period II, P-II, 1996; Period-III, P-III; 2002). Methods : There were 60...
The Significance of the Early Electroencephalographic Findings in Severely Asphyxiated Newborn Infants
Jong Uk Lee, Won Joung Choi, Chun Soo Kim, Sang Lak Lee, Jun Sik Kim
Clin Exp Pediatr. 2003;46(8):784-788.   Published online August 15, 2003
Purpose : Perinatal asphyxia occurring in newborn is one of the major causes of acute mortality and chronic neurological disability in survivors. We have studied the relationship between early electroencephalography(EEG) findings and clinical course and neurologic outcome in severe asphyxiated neonates. Methods : Between the period of July 1999 and June 2002, 25 neonates who were diagnosed with severe perinatal asphyxia(1-minute...
Maternal and Neonatal Outcome of Twin Pregnancies after in vitro Fertilization and Embryo Transfer
Kyung-Ah Kim, Uoo-Gyung Min, Jae-Woo Lim, Nu-Lee Jun, Hye-Sung Won, Chung-Hoon Kim, Ellen Ai-Rhan Kim, Pil-Ryang Lee, In-Sik Lee, Ki-Soo Kim, Ahm Kim, Soo-Young Pi
Clin Exp Pediatr. 2003;46(3):224-229.   Published online March 15, 2003
Purpose : To examine various neonatal outcomes and perinatal factors resulting from assisted reproduction compared to that of spontaneous conception. Methods : This is a retrospective study. The control cases were all twins of spontaneous conception born between periods from January 1995 to June 2000. The study cases were identified from twins conceived by assisted reproduction in the same time peried....
Effects of Single Fetal Death on Mother and Live Co-twin in Twin Pregnancy
So Youn Kim, Hae Yul Chung, Hee Jo Back, Ic Sun Choi, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2002;45(12):1512-1518.   Published online December 15, 2002
Purpose : Twins have a higher mortality and morbidity than singletons. Co-twin with one fetal death is particularly at risk. We investigated the neonatal outcome of live co-twins when one fetus had died after the 20th gestational week, and associated risk factors. Methods : A retrospective study was performed in fifteen cases of twin pregnancy with single intrauterine fetal deaths...
Changes in the Outcomes of Very Low Birth Weight Infants
Shung Shin Kim, Moon Hee Kim, Jae Won Shin, Sun Young Ko, Eun Kyung Lee, Yun Sil Chang, I Seok Kang, Won Soon Park, Mun Hyang Lee, Sang Il Lee, Heung Jae Lee
Clin Exp Pediatr. 2002;45(7):828-835.   Published online July 15, 2002
Purpose : The outcomes of infants weighing less than 1,500 gm(very low birth weight infant : VLBWI) reflect recent progress in neonatal intensive care. In this study, we analyzed changes over time in survival rate and morbidity of VLBWIs during the past seven years. Methods : A retrospective review of medical records was analyzed for VLBWIs admitted to the neonatal intensive...
Relationship between Brain MRI and Neurodevelopmental Outcome in Term Infants with Severe Hypoxic Ischemic Encephalopathy
Sun Young Park, Kyoung Sim Kim, Sung Soo Rim, Byung Soon Kang, Eun Young Kim, Yong Wook Kim, Se Jong Kim
Clin Exp Pediatr. 2001;44(2):139-148.   Published online February 15, 2001
Purpose : We analyzed the relationship between MRI patterns and neurologic outcome and explored the effectiveness of MRI as a tool for predicting the outcome. Methods : We analyzed 23 full term infants with severe HIE retrospectively who were admitted to our NICU from Sep. 1993 to May 1998. Their MRI findings were classified into 4 patterns : type I :...
A Study on the Prediction of Neurodevelopmental Outcome by Cranial Ultrasound in Preterm and Low Birth Weight Infants
Ji Young Rha, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2000;43(8):1037-1045.   Published online August 15, 2000
Purpose : Recent progress in neonatal medicine increased the survival of preterm low birth weight infants. However, neurodevelopmental sequelae are ever increasing. We carried out this study to determine whether serial cranial ultrasonographic findings could predict neurodevelopmental outcome. Methods : Four hundred and forty-one preterm low birth weight infants, who were admitted to the Neonatal Intensive Care Unit of Chonnam University...
Factors Related to the Outcome of Neonatal Seizures
Sung Koo Kim, Ran Lee, In Kyu Lee, Ki Joong Kim, Young Seung Hwang
Clin Exp Pediatr. 2000;43(2):267-273.   Published online February 15, 2000
Purpose : Seizures during the neonatal period may be an important indicator of serious neurologic abnormalities and can cause permanent neurologic sequelae. We attempted to find and analyze the factors related to the outcome of neonatal seizures. Methods : Seventy-six newborns with seizure were reviewed. The outcomes were analyzed according to etiologic diseases, gestational ages, characteristics of seizure, and neuroimaging and...
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Analysis of Auditory Brainstem Response in the Infants at High Risk for Hearing Disability
Kang Ho Cho, Myoung Jae Chey
Clin Exp Pediatr. 1995;38(10):1315-1323.   Published online October 15, 1995
Purpose : This study is performed to evaluate the clinical course, degree of hearing impairment and neurologic outcome of the infants at high risk for hearing disability. Methods : The 603 infants who had risk factors, such as severe birth asphyxia, hiperbilirubinemia requiring exchange transfusion, head and neck anomaly every low birthweight under 1500gm, family history of childhood hearing impairment, bacterial...
Meta-analysis of Impact of Neonatal Intensive Care on Neurodevelomental Outcome of Very Low Birth Weight Infants
Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1994;37(7):937-945.   Published online July 15, 1994
We analyzed neurodevelopmental outcome data of 36 selected studies. Data of individual studies were pooled by birth weight group: <800g, <1,000g, <1,500g and by time period of birth year: Period I(pre-intensive care era), 1960-67:Period II(beginning period of intensive care), 1968-76:and Period III(established period of intensive care), 1977-87. In all weight groups, survival and intact outcome rates based on live birth have...
Risk Factors and Outcome of Bronchopulmonary Dysplasia
Beyong Il Kim, Yun Sil Chang, Dong Woo Son, Hae Kyung Han, Jung-Hwan Choi, Chong Ku Yun, In One Kim, Kyung Mo Yeon, Je G. Chi
Clin Exp Pediatr. 1994;37(1):78-88.   Published online January 15, 1994
The 45 neonates with bronchopulmonary dysplasia among 355 neonates who were managed with mechanical ventilation and oxygen therapy in NICU of Seoul National University Chhildren's Hospital from January 1, 1968 to December 31, 1991, were analyzed for risk factors and outcome. The results were as follows: 1) The incidence of bronchopulmonary dysplasia was 12.7% 2) Respiratory Distress Syndrome was most common underlying problem. 3)...
Growth Outcome in Congenital Hypothyroidism
Mi Jung Park, Ho Seong Kim, Duk Hi Kim
Clin Exp Pediatr. 1993;36(5):713-720.   Published online May 15, 1993
Congenital hypothyroidism is one of the most common endocrine disease in childhood and it causes not only mental retardation but also growth retardation. There were many papers about evaluation of developmental outcome in congenital hypothyroidism, The aim of this study was to evaluate growth outcome in congenital hypothyroidism. We evaluated 65 patients with congenital hypothyroidism diagnosed at yonsei University College...
Periventricular Leukomalacia -Ultrasonographic Findings, Risk Factors and Neurological Outcome-
Kyeong Hee Cho, Myoung Jae Chey, Sejung Sohn, Kil Hyun Kim, Hak Soo Lee, Young Seok Lee, Dae Joong Kim
Clin Exp Pediatr. 1993;36(5):693-704.   Published online May 15, 1993
The thirty eight newborn infants with periventricular leukomalacia who were admitted to the neonatal intensive care unit of Gil General Hospital from March 1, 1988 to June 30, 1991, were investigated for ultrasonographic findings, risk factors and neurological outcome. The results were as follows: 1) There were 38 cases of PVL including 21 echogenic flarings and 17 cystic PVL뭩. 2) Mean birth weight...
Neonatal hypocalcemia: clinical manifestations and prognosis.
Jeong Lim Kim, Heung Dong Kim, Chang Jun Coe
Clin Exp Pediatr. 1991;34(7):912-920.   Published online July 31, 1991
Hypocalcemia during the newborn period is relatively common particularly in infants with predis- posing factors, such as prematurity, low birth weight, birth asphyxia and diabetic mothers and it is often manifested by various clinical findings. Some authors have reported that in some cases of the neonatal hypocalcemia, there were neurologic deficits such as irritability and convulsion, and neur- ologic sequelae on follow up. It...
Neurologic Outcome in Congenital Hypothyroidism.
Byeung Ju Jeoung, Duk Hi Kim, Chang Jun Coe, Hang Cho Kang
Clin Exp Pediatr. 1988;31(7):901-913.   Published online July 31, 1988
Congenital hypothyroidism is one of the most common endocrine disease in childhood and is a major cause of mental retardation. It is clear that the earlier treatment is started, the better intellec- tual potential and the likely absence of neurological sequellae. The present study was carried out to try to define the incidence and the nature of the neurologic disorders and to examine the...