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Review Article
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Behavioral insomnia in infants and young children
Eun Kyeong Kang, Seung Soo Kim
Clin Exp Pediatr. 2021;64(3):111-116.   Published online July 15, 2020
• Behavioral insomnia is common and affects a child’s daytime functioning and emotions.
• Diagnosing insomnia using the child’s sleep history, a sleep diary/log, and sleep questionnaires is important.
• Behavioral intervention, the main treatment, involves creating positive associations with sleep, establishing a consistent sleep schedule and bedtime routines, and the development of selfsoothing skills.
Systematic review and meta-analysis
Neurobehavior
Evaluation of drug interventions for the treatment of sleep disorders in children with autism spectrum disorders: a systematic review
Ensiyeh Jenabi, Sara Ataei, Saeid Bashirian
Clin Exp Pediatr. 2019;62(11):405-409.   Published online October 2, 2019
A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the...
Original Article
Cardiology
The improvement of right ventricular function after adenotonsillectomy in children with obstructive sleep apnea
Dong Yeop Kim, Kyung Ok Ko, Jae Woo Lim, Jung Min Yoon, Young Hwa Song, Eun Jeong Cheon
Clin Exp Pediatr. 2018;61(12):392-396.   Published online October 26, 2018

Purpose: Adenotonsillar hypertrophy (ATH) that causes upper airway obstruction might lead to chronic hypoxemic pulmonary vasoconstriction and right ventricular (RV) dysfunction. We aimed to evaluate whether adenotonsillectomy (T&A) in children suffering from obstructive sleep apnea (OSA) due to severe ATH could improve RV function. Methods: Thirty-seven children (boy:girl=21:16; mean age, 9.52±2.20 years), who underwent T&A forsleep apnea due to ATH, were...
General Pediatrics
Sleep problems in children and adolescents at pediatric clinics
Dong Soon Kim, Cho Long Lee, Young Min Ahn
Clin Exp Pediatr. 2017;60(5):158-165.   Published online May 31, 2017
Purpose

To investigate the frequency of childhood sleep problems at pediatric clinics in Seoul and Gyeonggi provinces.

Methods

Children (n=936) and their parents who visited 5 primary and 1 secondary pediatric outpatient clinics were invited to complete a Pediatric Sleep Questionnaire.

Results

Among patients, 901 (96.3%) answered questionnaires in sufficient detail for evaluation. The participant's mean age was 4.35±3.02 years (range, 0–18 years). The male...

Effect of adenotonsillar hypertrophy on right ventricle function in children
Jin Hwan Lee, Jung Min Yoon, Jae Woo Lim, Kyung Og Ko, Seong Jun Choi, Jong-Yeup Kim, Eun Jung Cheon
Clin Exp Pediatr. 2014;57(11):484-488.   Published online November 30, 2014
Purpose

Chronic upper airway obstruction causes hypoxemic pulmonary vasoconstriction, which may lead to right ventricle (RV) dysfunction. Adenotonsillar hypertrophy (ATH) is the most common cause of upper airway obstruction in children. Therefore, we aimed to evaluate RV function in children with ATH.

Methods

Twenty-one children (male/female, 15/6; mean age, 92.3¡¾39.0 months; age range, 4-15 years) with ATH and 21 healthy age- and gender-matched...

Depression and marital intimacy level in parents of infants with sleep onset association disorder: a preliminary study on the effect of sleep education
Sihyoung Lee, Seonkyeong Rhie, Kyu Young Chae
Clin Exp Pediatr. 2013;56(5):211-217.   Published online May 28, 2013
Purpose

Sleep onset association disorder (SOAD) is a form of behavioral insomnia observed in children that is caused by inappropriate sleep training. SOAD typically disturbs the sleep of not only infants and children but also their parents. We investigated levels of depression and marital intimacy among parents of infants with typical SOAD, to understand the influence of SOAD on family dynamics,...

Case Report
Pulmonary hypertension due to obstructive sleep apnea in a child with Rubinstein-Taybi syndrome
Hyung Soon Choi, Jeong Jin Yu, Young-Hwue Kim, Jae-Kon Ko, In-Sook Park
Clin Exp Pediatr. 2012;55(6):212-214.   Published online June 21, 2012

Rubinstein-Taybi syndrome (RTS) is characterized by peculiar facies, mental retardation, broad thumbs, and great toes. Approximately one-third of the affected individuals have a variety of congenital heart diseases. They can also have upper airway obstruction during sleep, due to hypotonia and the anatomy of the oropharynx and airway, which make these patients susceptible to obstructive sleep apnea (OSA). In our...

Original Article
Sleep patterns and school performance of Korean adolescents assessed using a Korean version of the pediatric daytime sleepiness scale
Seonkyeong Rhie, Sihyoung Lee, Kyu Young Chae
Clin Exp Pediatr. 2011;54(1):29-35.   Published online January 31, 2011
Purpose

Korean adolescents have severe nighttime sleep deprivation and daytime sleepiness because of their competitive educational environment. However, daytime sleep patterns and sleepiness have never been studied using age-specific methods, such as the pediatric daytime sleepiness scale (PDSS). We surveyed the daytime sleepiness of Korean adolescents using a Korean translation of the PDSS.

Methods

We distributed the 27-item questionnaire, including the PDSS and...

Review Article
Treatment of obstructive sleep apnea in children
Young Min Ahn
Clin Exp Pediatr. 2010;53(10):872-879.   Published online October 31, 2010

Obstructive sleep apnea (OSA) in children is a frequent disease for which optimal diagnostic methods are still being defined. Treatment of OSA in children should include providing space, improving craniofacial growth, resolving all symptoms, and preventing the development of the disease in the adult years. Adenotonsillectomy (T&A) has been the treatment of choice and thought to solve young patient's OSA...

Obstructive sleep apnea syndrome in children: Epidemiology, pathophysiology, diagnosis and sequelae
Sun Jung Chang, Kyu Young Chae
Clin Exp Pediatr. 2010;53(10):863-871.   Published online October 31, 2010

The prevalence of pediatric obstructive sleep apnea syndrome (OSAS) is approximately 3% in children. Adenotonsillar hypertrophy is the most common cause of OSAS in children, and obesity, hypotonic neuromuscular diseases, and craniofacial anomalies are other major risk factors. Snoring is the most common presenting complaint in children with OSAS, but the clinical presentation varies according to age. Agitated sleep with...

Original Article
Discrimination between obstructive sleep apnea syndrome and primary snoring in children : comparison of clinical parameters and behavioral disturbance
Hyun-Joo Seo, Jae Suk Lee, Hong-Beom Shin, Eui-Joong Kim, Hyun-Joon Shim, Young-Min Ahn
Clin Exp Pediatr. 2008;51(3):267-275.   Published online March 15, 2008
Purpose : To determine whether primary snoring could be distinguished from obstructive sleep apnea syndrome (OSAS) by clinical evaluation and symptom scores. Methods : 56 snoring and 20 asymptomatic subjects were recruited and polysomnography was used to confirm that there were 39 OSAS, 17 primary snoring, and 20 control subjects. We evaluated the size of the childrens adenoids and tonsils....
Review Article
Non-epileptic paroxysmal events during sleep - Differentiation from epileptic seizures -
In Kyu Lee
Clin Exp Pediatr. 2007;50(8):726-731.   Published online August 15, 2007
This review describes the wide spectrum of paroxysmal events during sleep in infancy and childhood. The differential diagnosis between sleep-related non-epileptic paroxysmal events and epileptic seizures is difficult in special occasions. The nocturnal frontal lobe seizure and of the more common non- epileptic paroxysmal events during sleep are described. The main differentiating features characterizing parasomnias are: onset in early...
Sleep disorders in childhood
Byung Ho Cha
Clin Exp Pediatr. 2007;50(8):718-725.   Published online August 15, 2007
Sleep disorders are very common among pediatric patients. Its prevalence is between 10% and 45% in preschool- and school-aged children. However parents commonly do not concern about their children's sleeping habits and for many pediatricians, there is not part of the routine office visit about a childs sleep. Sleep disorders were classified by International Classification of Sleep Disorder (ICSD) as...
Physiology of sleep
Kyu Young Chae
Clin Exp Pediatr. 2007;50(8):711-717.   Published online August 15, 2007
Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Normal sleep comprises non-rapid eye movement (NREM) and REM periods that alternate through the night. Sleep usually begins in NREM and progresses through deeper NREM stages (2, 3, and 4 stages), but newborns enter REM sleep (active sleep) first before NREM (quiet sleep). A...
Original Article
A survey of infant sleep positions associated with sudden infant death syndrome
Dong Jun Lee, So Ick Jang, Eun Jung Shim, Do Jun Cho, Dug Ha Kim, Ki Sik Min, Ki Yang Yoo
Clin Exp Pediatr. 2006;49(6):602-609.   Published online June 15, 2006
Purpose : As the prone position is thought to be an important factor in sudden infant death syndrome(SIDS), this study was conducted to contribute to reducing SIDS by analyzing sleeping positions of infants. Methods : A face-to-face questionnaire was carried out with a total of 170 parents with a baby aged less than 6 months. Results : A total of 170 infants...
A study on the effects of sleep position and of body weight on motor development
Kyong Yun Park, Ji Ung Kang, Young Taek Jang
Clin Exp Pediatr. 2006;49(4):375-380.   Published online April 15, 2006
Purpose : This study investigated how gross motor and fine motor development are influenced by sleep position. Methods : From December, 2003 to September, 2005, for a year and 9 months, 800 children aged from 3 months to 16 months, who visited the Presbyterian Medical Center, Chonju, Korea were surveyed for motor development scale, sleep position and body weight. Results : The...
Overnight Growth Hormone Secretions and Sleep Patterns in Idiopathic Short Stature Children
Sang Young Seo, Kee Hyoung Lee, Baik Lin Eun, Chang Sung Sohn, Young Chang Tockgo, Chol Shin, Baek-Hyun Kim
Clin Exp Pediatr. 2003;46(4):363-369.   Published online April 15, 2003
Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly...
Childhood Obstructive Sleep Apnea Syndrome : Clinical and Polysomnographic Findings
Yang Jun Park, Dae Kyun Koh, Jin Hee Oh, Soo Jung Lee
Clin Exp Pediatr. 2001;44(7):786-795.   Published online July 15, 2001
Purpose : Although pediatricians may see a lot of patients with clinically suspected obstructive sleep apnea syndrome(OSAS), the actual incidence, clinical and polysomnographic manifestations of OSAS in children have not well been recognized and reported cases are rare. The objective of this study was to evaluate the efficacy of polysomnography in the diagnosis of OSAS in children and to analyze...
Influence of Feeding and State of Alertness on the Incidence of Gastroesophageal Reflux in Children
Kyung Mo Kim, Jung Yeon Shim, Soo Jong Hong
Clin Exp Pediatr. 1997;40(10):1419-1426.   Published online October 15, 1997
Purpose : The aim of this study is to evaluate the influence of the feeding (fastingpostprandial) and the state of alertness(awake-asleep) on the amount of gastroesophageal reflux by using 24hour esophageal pH metry. Methods : From July 1994 to June 1995, 32 cases of 24 hour esophageal pH metry had been done at the Asan Medical Center. Twenty three children with normal pH monitoring and...
Case Report
A CaseofNarcolepsy Diagnosed by MultipleSleep Latency Test
Kharp Sue Yoo, Won Kyu Choi, Jae Seung Yang, Jong Soo Kim
Clin Exp Pediatr. 1997;40(2):265-269.   Published online February 15, 1997
Narcolepsy is a serious, lifelong, disabling disorder characterized by a tetrad of symptoms including excessive daytime sleepiness, cataplexy, hypnagogic hallucination, and sleep paralysis. We experienced a 14 year old boy with a narcolepsy diagnosed by typical clinical symptoms above mentioned and multiple sleep latency test. A brief review of the related literatures was also made.
Original Article
Sleep patern and night waking in infants.
Keun Lee
Clin Exp Pediatr. 1991;34(5):629-636.   Published online May 31, 1991
Night waking is very common in infancy and can be a transient phenomenon but, if it persists, it can be a symptom of more serious behavior disorders or emotional problems. To study the sleeping pattern and night waking in infants, a survey was taken on 219 parents of 3 month to 2 year old infants, at outpatient clinic of Department of Pediatrics, Ewha...
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