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Volume 45(6); Jun 2002
Clinical Lecture
Childhood Community-Acquired Pneumonia
Su Eun Park
J Korean Pediatr Soc. 2002;45(6):685-690.   Published online June 15, 2002
Medical Lecture Course
Molecular Genetic Synthesis and Clinical Applications of Single Chain Variable Fragments Antibodies
Seung Hwan Oh
J Korean Pediatr Soc. 2002;45(6):691-699.   Published online June 15, 2002
Original Articles
The Ewha Infant Develomental Screening Test
Keun Lee
J Korean Pediatr Soc. 2002;45(6):700-711.   Published online June 15, 2002
Purpose : Early identification and treatment of developmental disabilities is of considerable importance in the health care of children. Screening of development is aimed at identifying infants who may need more comprehensive evaluations. Methods : A new test, the Ewha Infant Development Screening Test(EDST) has been created to screen the development of infants, 0-4 years of age. EDST was constructed so...
Analgesic Effect of Sugar Solution in Infantile Colic
Jong Seok Kim, Kyung Ho Kwon, Young A Lee, Hyeon Jeong Kim, Kyun Woo Lee
J Korean Pediatr Soc. 2002;45(6):712-718.   Published online June 15, 2002
Purpose : Infantile colic is one of the most commonly encountered problems, characterized by excessive crying in apparently healthy young infants within the first 3 months of life. It is commonly assumed that the infant with colic has distress and possible pain. In recent investigations, it has been found that sucrose has an analgesic effect in newborn infants. The purpose...
Nosocomial Infection in Neonatal Intensive Care Unit
Hye Jung Kwon, So Youn Kim, Chang Yee Cho, Young Youn Choi, Jong Hee Shin, Soon Pal Suh
J Korean Pediatr Soc. 2002;45(6):719-726.   Published online June 15, 2002
Purpose : Neonates in neonatal intensive care units(NICU) have a high risk of acquiring nosocomial infection because of their impaired host defence mechanism and invasive procedures. Nosocomial infection result in considerable morbidity and mortality among neonates. This study was carried out to survey both the epidemiology of nosocomial infection in our NICU and the annual trends of pathogens. Methods : We...
Sequential Analysis of Hepatitis Be Antigen Status in Infants Born to Hepatitis Be Antigen-Positive Mothers
Eun Sook Park, Hae Kyung Lee, Chang Hee Oh, Sung Ku Kim, Hae Sun Yun, Won Keun Song, Young Ah Lee
J Korean Pediatr Soc. 2002;45(6):727-731.   Published online June 15, 2002
Purpose : The objectives of this study are to evaluate the significance of HBeAg positivity in infants born to HBeAg and HBsAg positive mothers. Methods : The HBeAg status of 22 HBeAg positive, HBsAg negative infants born to HBeAg and HBsAg positive mothers from December 1996 to March 1999 were evaluated by enzyme immunoassay. Results : The number of HBsAg positive...
Effect of Xanthine Oxidase Inhibitor on Cerebral Hypoxia-Ischemia in Neonatal Rats
Dae-Ho Choi, Yeon-Kyun Oh, Seung-Tak Park
J Korean Pediatr Soc. 2002;45(6):732-742.   Published online June 15, 2002
Purpose : In order to evaluate the hypoxia-ischemia(H-I) induced neurotoxicity and the protective effect of xanthine oxidase(XO) inhibitor(allopurinol), cell number, cell viability, lactate dehydrogenase(LDH), protein synthesis(PS) and protein kinase C(PKC) activity were measured in cerebral neurons and astrocytes. Methods : Cytotoxic effect was measured by in vitro assay at 12-72 hours after H-I on cerebral neurons and astrocytes derived from 7-day...
Changes of Bone Metabolism Markers and Bone Mineral Density with Improvement of Thyroid Function in Children and Adolescents with Hyperthyroidism
Min Ho Jung, Choong Ho Shin, Sei Won Yang, Byung Churl Lee
J Korean Pediatr Soc. 2002;45(6):743-753.   Published online June 15, 2002
Purpose : Dynamics of bone mineral density(BMD) and bone metabolism in children and adolescents with hyperthyroidism have not been thoroughly investigated. The aim of this study was to study how the improvement of thyroid function with antithyroid treatment influenced bone metabolism and BMD in children and adolescents with hyperthyroidism. Methods : Serum levels of osteocalcin(OC), bone-specific alkaline phosphatase(b-ALP), and carboxyterminal telopeptide...
Clinical Characteristics of Type 2 Diabetes in Children and Adolescents
Seong Yong Lee, Choong Ho Shin, Sei Won Yang
J Korean Pediatr Soc. 2002;45(6):754-763.   Published online June 15, 2002
Purpose : The incidence of type 2 diabetes in children and adolescents has been reported to increase recently. The aim of this study is to investigate the clinical features of type 2 diabetes developing during childhood and adolescent period. Methods : The medical records of 33 patients with type 2 diabetes were reviewed. We analysed clinical manifestations, demographic data, and modes...
Effects of Insulin Level on Dyslipidemia in Children with Simple Obesity
Jung Sub Lim, Choong Ho Shin, Sei Won Yang
J Korean Pediatr Soc. 2002;45(6):764-772.   Published online June 15, 2002
Purpose : Obesity is closely related to insulin resistance, compensatory hyperinsulinemia and dyslipidemia in adults. We identified the effect of obesity measured by BMI and insulin resistance on dyslipidemia in children and adolescents. Methods : The fasting serum insulin, glucose, total cholesterol, triglyceride, HDL- and LDL-cholesterol were measured and insulin resistance(HOMA-IR) was calculated in 35 children with simple obesity(age :...
Comparison of Acute Clinical Features and Coronary Involvement in Patients with Kawasaki Disease between Those Younger and Older than One Year of Age
So Young Kim, Seong Joon Lim, Sin Weon Yun, Dong Keun Lee, Eung Sang Choi
J Korean Pediatr Soc. 2002;45(6):773-782.   Published online June 15, 2002
Purpose : To identify the necessity of more reasonable diagnostic criteria and the possibility of early prediction of coronary involvement in the higher risk group, we investigated and compared clinical and laboratory findings in the acute phase and coronary involvements in those younger (n=17) and older(n=53) than one year of age in Kawasaki disease(KD). Methods : Retrospective chart reviews were performed...
An Epidemiologic Study of Kawasaki Disease(1987-2000) : Incidence of Coronary Artery Complication in the Acute Stage
Kyung-Yil Lee, Min-Young Park, Ji-Whan Han, Hyung-Shin Lee, Jin Choi, Kyung-Tai Whang
J Korean Pediatr Soc. 2002;45(6):783-789.   Published online June 15, 2002
Purpose : We evaluated the epidemiologic characteristics and incidence of coronary artery sequele of children with KD according to treatment. Methods : We retrospectively analyzed 506 medical records of children with KD, who were admitted at Daejeon St. Mary's Hospital from Jan. 1987 to Dec. 2000. Results : The mean annual incidence was 36.1±11.1 cases per year. There was a slightly higher...
Case Reports
A Case of Hypernatremic Dehydration in an Exclusively Breast-Fed Newborn Infant
Kyung Pil Park, Jin Kyung Kim, Heng Mi Kim
J Korean Pediatr Soc. 2002;45(6):790-795.   Published online June 15, 2002
Sporadic reports of hypernatremic dehydration in breastfed newborn infants have appeared in medical literature for at least 3 decades. We report the first case of hypernatremic dehydration resulting from inadequate breast-feeding in Korea. A 14-day old baby, born to a mentally retarded mother, was transferred to our hospital with a body weight loss of 460 g since birth(17%) and a...
A Case of Thyroxine Binding Globulin Deficiency with Hypothyroidism
Dong-Chul Lee, Sun-Hee Lee, Jae-Hong Yu
J Korean Pediatr Soc. 2002;45(6):796-799.   Published online June 15, 2002
A child diagnosed with congenital hypothyroidism after newborn screening and follow up thyroid function test at 1 month of life in another general hospital demonstrated euthyroid state with thyroxine(T4) supplementation until the age of 22 months of life, when he was transferred to our hospital, where he was diagnosed as thyroxine binding globulin(TBG) deficiency with low T4 and TBG. Withdrawal...
A Case of Phthiriasis Palpebrarum in the Eyelids of a Child
Jong Hyuck Lee, Sang Hoon Rah, Yoon Hee Kim, Won Seok Song
J Korean Pediatr Soc. 2002;45(6):800-803.   Published online June 15, 2002
A two year old male child complained of foreign body sensations bilaterally, and an itching sensation at both upper and lower eyelids for 2 months of duration. He was diagnosed with Phthiriasis palpebrarum after observation of adult louse and nits on slit-lamp examination. The treatment was accomplished by mechanical removal of the lices and nits by forceps and scissors, and...
A Case of Trisomy 22 with Pulmonary Hypoplasia in a Liveborn Infant
Myoung-Bum Choi, Ki Su Kang, Chan-Hoo Park, Hyang-Ok Woo, Jeong-Hee Lee, Jae-Ik Lee, Won Young Paik, Hee-Shang Youn
J Korean Pediatr Soc. 2002;45(6):804-808.   Published online June 15, 2002
We report a case of trisomy 22 in a liveborn male infant which was confirmed by fluorescence in situ hybridization(FISH), macrocultures and GTG-banding, and RHA-banding procedures of peripheral white blood cells. The infant showed lung hypoplasia, which is a unique presentation, with other clinical manifestations of previously reported cases of trisomy 22, such as intrauterine growth retardation, cleft palate, micrognathia,...