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Volume 31(8); Aug 1988
Original Articles
A Clinical and Epidemiological study on Rotavirus Gastroenteritis in Children.
Hye Kyung Chang, Chang Yeol Kim, Sung Hee Oh, Ha ik Lee, Kun Soo Lee
J Korean Pediatr Soc. 1988;31(8):961-967.   Published online August 31, 1988
We investigated the clinical and epidemiological characteristics of rotavirus gastroenteritis in children. The study included 1697 children with acute diarrhea who admitted to the Department of Pediatrics in Hanyang University Hospital from March 1983 through February 1987. The stool specimens were cultured to isolate Campylobacter, Shigella and salmonella and tested for rotavirus by ELISA. The results were 1) Rotavirus was isolated in 646 cases (38.1%) out of total...
A Prospective Study of Urinary beta2 -Microglobulin in Infants with Meconium-Stained Amniotic Fluid.
Sung Oh Kim, Jeh Hoon Shin, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
J Korean Pediatr Soc. 1988;31(8):968-976.   Published online August 31, 1988
We studied prospectively whether events that result in meconium staining may be associated with additional abnormalities that are not clinically apparent associated by measurements of urinary concentrations of β₂-microglobulin indicating renal proximal tubular functions. Among 61 fullterm, healthy neonates delivered at Hanyang University Hospital during the period of September 1986 through April 1987, urinary concentration of β₂-microglobulin and creatinine were measured during the immediate perinatal...
Statistical Assessment on Chromosomal Aberrations observed on Childhood.
Seong Ho Kim, Jeh Hoon Shin, Soo Jee Moon, Hahng Lee, KeunSoo Lee, Youl Hey Cho, Myung So Ryu, Young Kyun Paik
J Korean Pediatr Soc. 1988;31(8):977-983.   Published online August 31, 1988
Chromosomal studies were carried out in 730 patients at the Dept, of Pediatrics and Genetics, Hanyang University Hospital, form December 1979 to April 1986. A statistical assessment was carried out in 244 cases who have chromosomal aberrations. The following results were obtained: 1) Chromosomal aberrations were observed in 244 cases among 730 cases, so the propotion of chromosomal aberrations was 33%. 2) Age distribution revealed 53% of chromosomal...
Lateral Ventricular Indices in tuberculous Meningitis.
Ja Wook Koo, Hang Bo Cho, In Joon Seol, soo Jee Moon, Hahng Lee, Keun Soo Lee
J Korean Pediatr Soc. 1988;31(8):984-991.   Published online August 31, 1988
Computed tomography is a very valuable method by which the pathogenic evolution of tuberculous meningitis may be followed, thereby facillitating its differential diagnosis and controlling the effi- ciency of therapy, and assessing the degree of hydrocephalus. Fifteen cases of clinically proven intracranial tuberculosis were studied by lateral ventricular indices of brain computed tomography in our hospital during last 3 years. The results were as follows: 1)...
A Clinical Ovservation of Tetanus Neonatorum.
Gyeong Hye Jung, Hyo Sin Kim, Ock Seung jeong, Son Sang Seo
J Korean Pediatr Soc. 1988;31(8):992-998.   Published online August 31, 1988
A clinical study in 75 cases who were hospitalized and diagnosed as neonatal tetanus at II Sin Christian Hospital during the last 10 years (1976-1985) is reported. The results were as follows; 1) The mean annual incidence was 0.29% and the overall mortality rate was 29.4%. 2) Sex ratio of male to female was 1.6:1. 3) Home delivery without sanitory facilities was the most common problem (86.5%). 4) Most of...
A Study of Maternal IgG Anti-A, B in ABO Hemolytic Disease of Newborn: Relation between Antibody titer in Mother and Clinical Severity in Neonate.
Chong Woo Bae, yong Mook Choi, Chang Il Ahn, Hyun Sook Chi
J Korean Pediatr Soc. 1988;31(8):999-1006.   Published online August 31, 1988
Only IgG anti-A, or Anti-B cross the placenta and are responsible for the occurrence of ABO hemolytic disease of newbom(HDN). We have conducted the role of IgG anti-A or anti-B in mothers to occurrence and severity of the disease with were related to the level of antibodies in pathogenesis of ABO-HDN. This report presents the relation between the degree of bilirubin, hemoglobin concentration in ABO-HDN...
Study on the Clitoral Size of the Korean Female Newborn.
Jong Lin Rhi, Sei Won Yang, Hyung Ro Moon
J Korean Pediatr Soc. 1988;31(8):1007-1013.   Published online August 31, 1988
The disturbance of sex hormone secretions during the fetal life results in abnormal development of the fetal sex organs including the external genitalia. In the congenital adrenal hyperplasia, especially, the external genitalia is often virilized at birth and the clitomegaly in this disorder can be an important clue for the early diagnosis. For the normal range of the clitoral size of the Korean female...
Evaluation of Pulmonary and Systemic Blood Flow by Doppler Echocardiography in Pediatric Congenital Heart Disease.
Jae Hong Park, Chun Dong Kim, Jin Gon Jun
J Korean Pediatr Soc. 1988;31(8):1014-1020.   Published online August 31, 1988
This study was designed to assess the accuracy of pulmonary (Qp) and systemic blood flow (Qs) and the ratio of pulmonary to systemic blood flow (Qp/Qs) measured by non-invasive range-gated pulsed Doppler echocardiography. Thirty five children with congenital heart disease, aged 4 months to 15 years, admitted for cardiac operation to this hospital, were studied. Cardiac outputs were measured by 2-dimensional range-gated pulsed Doppler...
Plasma Renin Activity (PRA) in Peripheral Vein and Renal Veins in Normotensive Children with Cyanotic Congenital Heart Disease.
Sang Kyu Park, Hae Il Cheong, Chung Il Noh, Yong Soo Yun, Yong Choi, Kwang Wook Ko
J Korean Pediatr Soc. 1988;31(8):1021-1027.   Published online August 31, 1988
PRA’s in peripheral vein, both renal veins, and inferior vena cava (IVC) were measured in 25 normotensive children without renal disease undergoing cardiac catheterization for their underlying cyanotic congenital heart disease. And we presented the results as reference values/ranges of PRA in children. 1) There was no significant difference in PRA between both side renal veins at any absolute PRA levels with a mean ratio (RT/LT)...
Goiter in Children.
Young Wan Kim, Duk Hi Kim, Byeung Ju Jeoung
J Korean Pediatr Soc. 1988;31(8):1028-1036.   Published online August 31, 1988
We studied 197 cases of patients with goiter who visited Department of Pediatrics, Yonsei University College of Medicine from January 1980 to June 1987. For each patient, serum T4, free T4, T3, TSH, antithyroid antibody, and antimicrosomal antibody were analyzed, thyroid scan was performed, and radioiodine uptake was measured. Following results were obtained: 1) Male to female ratio of 197 cases of goiter was 1:7.5, predominent...
Thyriod Function Studies in Children with Nephrotic Syndrome.
In Hoon Lee, Chan Yung Kim
J Korean Pediatr Soc. 1988;31(8):1037-1047.   Published online August 31, 1988
To evaluate the influence of nephrotic syndrome on the thyroid function test in children, serum T3, T4, free T4, TSH, TBG and rT3 were measured using radioimmunoassay in 14 clinically euthyroid children with nephrotic syndrome who were admitted to Department of Pediatrics, Pusan National University Hospital from July, 1986 to August, 1987. Control group was 15 children who visit our outpatient department for minor...
A Case of Tsutsugamushi Disease.
Tae Kyu Hame, Soo Chun Kim, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn
J Korean Pediatr Soc. 1988;31(8):1048-1053.   Published online August 31, 1988
Rickettsial infection has not been identified in Korea since about 20-30 years before in Korea. However, there has been an increasing incidence of Tsutsugamushi disease in recent years. Tsutsugamushi disease is a variety of rickettsial infection to human causing abrupt onset of fever, headadie, vomiting, myalgia, and abdominal pain. In severe case, causing D.I.C., pulmonary edema, hypoalbuminemia and generalized edema. We reported a case of...
A Case of Iron Deficiency Anemia with Hypoproteinemia.
Seong Ho Kim, Woo Kill Lee
J Korean Pediatr Soc. 1988;31(8):1054-1058.   Published online August 31, 1988
Severe iron deficiency anemia is occasionally accompanied by hypoproteinemia and edema. There is evidence that the hypoproteinemia is caused by increased intestinal loss of serum protein. We experienced a case, 1 year and 6 months old female patient with generalized edema, diagnosed as iron deficiency anemia with hypoproteinemia. After treatment with ferrous iron preparation, generalized edema was subsided, and hemoglobin value and serum protein...
A Case of Hemolytic Disease of Newborn due to Anti-E.
Sang Keun Oh, Youn O Park, hyun Sook Seo, Mi Sook Park, Young Chul Lee, Hee Dae Park, Hee Joo Lee
J Korean Pediatr Soc. 1988;31(8):1059-1063.   Published online August 31, 1988
A 2-day-old male infant was admitted to the Incheon Christian Hospital due to severe jaundice. He was a third baby and his Rh phenotype was CcDEe. The direct antiglobulin test of the infant was strong positive. Eluates that were made from the infanfs elder brother and sister were both CDe. Her two previous infants showed no evidence of erythroblastosis. She had a past...
A Case of Acute Megakaryoblastic Leukemia in Infant with Down's Syndrome.
Jung Soon Whang, Soon hee Kim, Moon Ja Kim, Keun Lee, Je Geun Chi
J Korean Pediatr Soc. 1988;31(8):1064-1070.   Published online August 31, 1988
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal course. Abnormalities in chromosome 21 may have a more than random relationship to acute megakaryoblastic leukemia. The authors reports a case of acute megakaryoblastic leukemia in a 2 month old female patient who was admitted for evaluation of hepatosplenomgaly. Multiple organ infiltration...
A Case of Ectopic ACTH Syndrome Caused by Wilms Tumor.
Dong Hun Chi, Sang Bong Han, Young Jong Woo, Tai Ju Hwang
J Korean Pediatr Soc. 1988;31(8):1071-1078.   Published online August 31, 1988
We experienced a extremely rare case of ectopic ACTH syndrome caused by Wilms tumor in a 4 year 8 month-old female patient. We performed specific radiologic and hormonal studies. Diagnosis was confirmed by histologic and biochemical findings of tumor mass after right nephrectomy. A brief review of related literature was made.
A Case of Toxic Epidermal Necrolysis.
Eun Hwa Shin, Youn Hong Choi, Ju Hong Cha, Kwang Jun Kim, Kyung Je Sung
J Korean Pediatr Soc. 1988;31(8):1079-1084.   Published online August 31, 1988
Toxic Epidermal Necrolysis is uncommon disease characterized by erythema and shedding of the epidermis and mucous membrane. Mortality rates are high. The reaction is probably a drug-induced hypersensitivity phenomenon. We experienced Toxic Epidermal Necrolysis in a 4 yr old boy whose skin lesion had developed 3 days after taking medication from a drug store for common cold. Diagnosis of TEN was established by clinical...
Two Cases of Osteogenesis Imperfecta Congenita.
Soon Soen Lim, Byeung Ho Lee, Young Ha Kim, Moon Ki Joe
J Korean Pediatr Soc. 1988;31(8):1085-1090.   Published online August 31, 1988
Osteogenesis imperfecta is an inherited disorder of connective tissue that affects the skeleton, ligament, skin, sclerae and dentin. It is thought to be characterized by the abnormal maturation of collagen in both mineralized and nonmineralized tissues. The three major clinical criteria are osteoporosis with abnormal fragility of the skeleton, blue sclerae and dentinogenesis imperfecta. The presence of two of these abnormalities confirms the diagnosis. We have...
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