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Original Article
Initial steroid regimen in idiopathic nephrotic syndrome can be shortened based on duration to first remission
Hee Sun Baek, Ki-Soo Park, Hee Gyung Kang, Cheol Woo Ko, Min Hyun Cho
Clin Exp Pediatr. 2015;58(6):206-210.   Published online June 22, 2015
Purpose

The use of a 12-week steroid regimen (long-term therapy, LT) for the first episode of idiopathic nephrotic syndrome (NS) reportedly induces a more sustained remission and lower relapse rate than previous regimens, including an 8-week steroid regimen (short-term therapy, ST). Here, we assessed the potential for selective application of 2 steroid regimens (LT vs. ST) based on the days to...

Case Report
Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient
Eun-Mi Cho, Hye-Hyun Moon, Young-Ju Hwang, Seung-Jin Lee, Cheol Woo Ko, Min Hyun Cho
Clin Exp Pediatr. 2013;56(7):304-307.   Published online July 19, 2013

Polyclonal gammopathy represents the diffuse activation of B cells and is usually related to inflammation or immune-related diseases. However, the mechanisms leading to polyclonal gammopathy are essentially speculative. Generally, infectious, inflammatory, or various other reactive processes may be indicated by the presence of a broad-based peak or band in the gamma region on serum protein electrophoresis results. A 15-year-old girl,...

Original Article
Comparison of Therapeutic Efficacy between Lamivudine and Alpha-Interferon in Korean Children with Chronic Hepatitis B at Two Years after the Initiation of Treatment
Byung-Ho Choe, You Cheol Jang, Chang Hwan Jang, Ki Won Oh, Jun Hwa Lee, Cheol Woo Ko
Clin Exp Pediatr. 2005;48(1):55-62.   Published online January 15, 2005
Purpose : We compared the therapeutic efficacy of lamivudine and alpha-interferon in children with chronic hepatitis B two years after the initiation of treatment, so that we could verify the safety and long term efficacy of lamivudine in children. Methods : We prospectively studied 44 children(32 male and 12 female; age, 1-18 years, mean, 9 years) treated for chronic hepatitis B...
Case Report
A Case of Bilateral Perineal Ectopic Testes Treated with Hormone Therapy and Orchiopexy
Jae Hyoun Kim, Hung Min Park, Woo Gun Lee, Sung Kwang Chung, Cheol Woo Ko
Clin Exp Pediatr. 1999;42(10):1464-1466.   Published online October 15, 1999
Medical Lecture Course
Glomerular Basement Membrane Heparan Sulfate Proteoglycan (GBM HSPG)
Cheol Woo Ko
Clin Exp Pediatr. 1996;39(12):1643-1651.   Published online December 15, 1996
Original Article
Effect of Cyclosporin, Indomethacin and Methylprednisolone on Puromycin-Aminonucleoside Induced Nephrosis in Rats
Hong Bae Kim, Hae Lee Chung, Cheol Woo Ko, Ja Hoon Ko, Jung Sik Gwak
Clin Exp Pediatr. 1993;36(4):495-505.   Published online April 15, 1993
This experimental study was conducted to evaluate the effect of indomethacin and methylprednisolone on PAN-induced nephrosis in rats. Sprague-Dawley rats weighing 150∼200gm were used and divided into controls, group Ⅰ(PAN intraperitoneally), group Ⅱ(PAN intraperitoneally, followed by indomethacin peritoneally for 12 days), group Ⅲ(PAN intraperitoneally, followed by methylprednisolone peritoneally for 12 days) and group Ⅳ(PAN intraperitoneally, followed by cyclosporin subcutaneously for...
Altered secretion of arginine vasopressin in children with CNS diseases.
Kun Whe Kim, Eun Sook Kim, Cheol Woo Ko, Ja Hoon Koo, Doo Hong Ahn, Won Jung Lee
Clin Exp Pediatr. 1991;34(3):323-333.   Published online March 31, 1991
A prospective study was conducted to see the pattern and mechanism of arginine vasopressin (AVP) secretion in children with CNS diseases. Study population consisted of 21 cases with aseptic meningi- tis (meningitis group) and another 21 cases with viral encephalitis or encephalopathy (encephalitis group), who had been admitted to our Pediatric Department during 10 months’ period from April 1985 to January 1986. Seventeen healthy...
Changes of immune indices in children with recurrent gross hematuria (IgA nephropathy and non-IgA nephropathy) and Henoch-Schonlein purpura nephritis.
Seong Mi Kim, Myung Chul Hyun, Cheol Woo Ko, Ja Hoon Koo, Doo Hong Ahn, Jung Sik Kwack
Clin Exp Pediatr. 1991;34(3):317-322.   Published online March 31, 1991
A Prospective study was conducted to see the changes of immune system in recurrent gross hematuria (IgA nephropathy and non-IgA nephropathy) and HSP nephritis in children. Study patients consisted of 60 children with recurrent gross hematuria and Henoch-schdnlein purpura nephritis (8 IgA nephropathy, 24 non-IgA nephropathy and 28 HSP nephritis). The cellular immune indices (total T, T4, T8 cells and T4/T8 ratio) and humoral...
The Effect of Low-Dosage Alpha-Interferon Therapy in Children with Chronic Active Hepatitis B.
Hee Kyung Kim, Sung Min Choi, Cheol Woo Ko, Kun Soo Lee, Ja Hoon Koo, Doo Hong Ahn
Clin Exp Pediatr. 1990;33(7):915-922.   Published online July 31, 1990
A clinical trial was conducted to determine the effect of low-dosage recombinant a-interferon therapy in children with HBs Ag and HBe Ag positive chronic active hepatitis. Studied patients consist of 7 biopsy-proven children (aged 6.5-11.5 yr). After 16 weeks of therapy, following results were obtained. Out of 7 HBe Ag positive cases, 5 cases (71.4%) were converted to HBe Ag negative state. One of two...
Diagnostric Significance of Subxiphoid Two-Dimensional Echocardiography in Congenital Heart Desease of Chlidred.
Kwang Do Lee, Cheol Woo Ko, Hong Bae Kim, Sang Bum Lee, Doo Hong Ahn
Clin Exp Pediatr. 1986;29(3):296-304.   Published online March 31, 1986
Subxiphoid, two-dimensional echocardiographic examinations were performed and interpreted before diagnostic cardiac catheterization on 138 patients with suspected congenital heart disease who were from 2 months to 15 years old. Cardiac catheterization and cineangiographic examination were performed in all patients and surgery in 99 patients and comparisions were made with each other. Eighteen of nineteen patients with an atrial...