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Original Article
The efficacy of aspartate aminotransferase-to-platelet ratio index for assessing hepatic fibrosis in childhood nonalcoholic steatohepatitis for medical practice
Earl Kim, Yunkoo Kang, Seungmin Hahn, Mi Jung Lee, Young Nyun Park, Hong Koh
Clin Exp Pediatr. 2013;56(1):19-25.   Published online January 29, 2013
Purpose

Childhood obesity is associated with nonalcoholic fatty liver disease (NAFLD), and it has become one of the most common causes of childhood chronic liver diseases which significant as a cause of liver related mortality and morbidity in children in the United States. The development of simpler and easier clinical indices for medical practice is needed to identify advanced hepatic fibrosis...

Case Report
Steroid and enalapril therapy - possible cause of toxic epidermal necrolysis
Dong Wook Kim, Da Eun Jung, Ja Wook Koo
Clin Exp Pediatr. 2006;49(3):332-336.   Published online March 15, 2006
Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN is characterized by the sudden onset of extensive necrosis in the epidermis and frequent mucous membrane involvement. The pathogenesis has not yet been elucidated. In addition, no particular treatment for TEN has been established. We report a case of TEN in a 14-year-old-boy, which might have...
Original Article
Effects of Cisapride on QTc Interval and QT Dispersion in Preterm Infants
Heui Seung Jo, Chang Won Choi, Yun Kyung Lee, Hee Seok Kim, Jun Dong Park, Jun Huh, Beyong Il Kim, Chung Il Noh, Jung-Hwan Choi
Clin Exp Pediatr. 2000;43(2):188-194.   Published online February 15, 2000
Purpose : Cisapride, a prokinetic agent, is widely used in preterm infants with feeding intolerance or gastroesophageal reflux. Although cisapride is regarded as a safe drug, increased QTc interval or ventricular arrhythmia has been reported in adults and neonates. So we prospectively examined the effects of cisapride on the QTc interval and QT dispersion in preterm infants. Methods : QTc interval...
Effects of Cisapride on Action Potential Duration and on ATP-Sensitive K Channel in Guinea Pig Ventricular Muscles
Chan Uhng Joo, Young Jae Kim, Sung Ki Mun, Soo Wan Chae
Clin Exp Pediatr. 1999;42(7):953-958.   Published online July 15, 1999
Purpose : Cisapride(PrepulsidⓇ) has been recently associated with long QT syndrome. It has been reported to cause Torsades de Pointes and induce early afterdepolarization in rabbit Purkinje fibers. We investigated the electrophysiological effects of cisapride on cardiac action potential duration and ATP-sensitive K channel in papillary muscles. Methods : Cardiac action potentials in guinea pig papillary muscle were recorded with microelectrodes...
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