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Case Report
A case of atypical hemolytic uremic syndrome as an early manifestation of acute lymphoblastic leukemia
Dong Kyun Han, Hee Jo Baek, Young Kuk Cho, Chan Jong Kim, Myung Geun Shin, Hoon Kook, Tai Ju Hwang
Clin Exp Pediatr. 2010;53(2):253-257.   Published online February 15, 2010
Hemolytic uremic syndrome (HUS) is the most common cause of acute renal failure in children younger than 4 years and is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. HUS associated with diarrheal prodrome is usually caused by Shiga toxin-producing Escherichia coli O157:H7 or by Shigella dysenteriae, which generally has a better outcome. However, atypical cases show a...
Review Article
Acute renal failure in pediatrics
Hyewon Hahn
Clin Exp Pediatr. 2007;50(10):948-953.   Published online October 15, 2007
Acute renal failure is the generic term for an abrupt and sustained decrease in renal function resulting in retention of nitrogenous and non nitrogenous waste product. This may results in life threatening consequences including volume overload, hyperkalemia, and metabolic acidosis. Acute renal failure is both common and carries high mortality rate, but as it is often preventable, identification of patients...
Renal replacement therapy in children with acute renal failure
Kyung Hoon Paik
Clin Exp Pediatr. 2007;50(10):938-947.   Published online October 15, 2007
Many dialysis modalities such as peritoneal dialysis (PD), hemodialysis (HD) and continuous hemofiltration or hemodialysis (CRRT) are available for the management of pediatric patients with acute renal failure (ARF). PD is a relatively simple, inexpensive modality and can be used in hemodynamically unstable patients. But, it may not be the optimal therapy for patients with severe volume overload or life...
Original Article
Clinical characteristics of acute renal failure of rhabdomyolysis in children
Jae Hui Kim, Min Ji Goo, Jung Sook Yeom, Eun Sil Park, Ji Hyun Seo, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Hee Shang Youn
Clin Exp Pediatr. 2007;50(3):277-283.   Published online March 15, 2007
Purpose : Acute renal failure (ARF) is an important complication of rhabdomyolysis. The purpose of this study was to identify the major causes of rhabdomyolysis in children and to identify the factors associated with the developmet of ARF. Methods : A retrospective chart review between January 1997 to June 2005 was conducted of 60 patients with a diagnosis of rhabdomyolysis. Rhabdomyolysis...
Case Report
A Case of Acute Renal Failure Caused by Rhabdomyolysis due to Hyperosmolar Nonketotic Coma in Children
Jeong Won Kwak, Jae Min Oh, Su Yung Kim
Clin Exp Pediatr. 2005;48(5):565-568.   Published online May 15, 2005
Hyperosmolar nonketotic coma complicated in diabetes mellitus has been a rare cause of rhabdomyolysis, although increasingly reported recently. Acute renal failure can be complicated in 15 percent of rhabdomyolysis patients, but is rare in the case of rhabdomyolysis caused by diabetic hyperosomolar nonketotic coma. We report a 14 years-old boy with acute renal failure complicated by rhabdomyolysis caused by diabetic...
Original Article
Outcome of Continuous Renal Replacement Therapy in Children
Yeon Jung Lim, Hyun-seung Jin, Hyewon Hahn, Sei Ho Oh, Seong Jong Park, Young Seo Park
Clin Exp Pediatr. 2005;48(1):68-74.   Published online January 15, 2005
Purpose : There is growing use of continuous renal replacement therapy(CRRT) for pediatric patients, but reports about the use and outcome of CRRT in children is rare in Korea. We report our experiences of CRRT in critically ill pediatric patients. Methods : We reviewed the medical records of 23 pediatric patients who underwent CRRT at Asan Medical Center between May 2001...
Case Report
A Case of Infantile Spasm Associated with Acute Renal Failure and Kwashiorkor after Ketogenic Diet
Young-Myoung Kim, Tae-Hong Kim, Jin-A Jung, Kyu-Geun Hwang
Clin Exp Pediatr. 2003;46(11):1131-1134.   Published online November 15, 2003
The ketogenic diet is a high-fat, low-protein, low-carbohydrate diet developed in the 1920s for the treatment of difficult-to-control seizures. Despite advances in both the pharmacotherapy and the surgery of epilepsy, many children continue to have difficult-to-control seizures. In this situation, a ketogenic diet should be considered as an alternative therapy. However, less attention has been paid to associated adverse events...
A Case of Kawasaki Disease Associated with Acute Renal Failure and Necrotizing Myositis
So Hyun Ahn, So Yun Shim, Sejung Sohn, Seung Joo Lee, Un Seop Han
Clin Exp Pediatr. 2003;46(2):207-209.   Published online February 15, 2003
Kawasaki disease is an acute febrile vasculitis affecting primarily infants and young children. In addition to the cardiovascular involvement, it may cause inflammatory changes in various organs and body systems : digestive, respiratory, urinary, nervous and musculoskeletal. A case is reported of atypical Kawasaki disease associated with acute renal failure and necrotizing myositis in the right gastrocnemius in a 10-year-old...
A Case of Acute Renal Failure Associated with Tsutsugamushi Disease
Jin Hee Hong, Jin Hee Oho, Jong Hyun Kim, Dae Kyun Kho
Clin Exp Pediatr. 2001;44(4):464-468.   Published online April 15, 2001
Tsutsugamushi disease is acute febrile illness, transmitted by Rickettsia tsutsugamushi. R. tsutusgamushi invade and proliferate in the endothelial cells of small blood vessels. Destruction of endothelial cells occurs from the proliferation of the organism and eventual disruption, and thus vascular rich organs must be carefully examined such as the kidney, lung, heart, liver. Recently we experienced a case of acute...
A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):720-724.   Published online May 15, 2000
Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG...
Original Article
Clinicial Observations of Oliguric Acute Renal Failure in Children
Sung-Soo Lee, Young-Mi Choi, Chong-Woo Bae, Sung-Ho Cha, Byoung-Soo Cho
Clin Exp Pediatr. 1999;42(10):1419-1425.   Published online October 15, 1999
Purposes : We studied the clinicial findings of oliguric acute renal failure(ARF) developed on admission or during treatment of other diseases. Methods : We performed a retrospective analysis of medical records of 118 patients with oliguric ARF who had been admitted to Kyunghee University Hospital since January 1988 to December 1997. Diagnostic criteria of oliguric ARF are serum creatinine>1.0mg/dl and urine...
Case Report
Rhabdomyolysis-induced Acute Renal Failure in a Child
Weon Sang Yun, Keun Mo Ki, Byung Ju Kim, Jae Sook Ma
Clin Exp Pediatr. 1998;41(5):707-710.   Published online May 15, 1998
Rhabdomyolysis has been reported as a cause of acute renal failure(ARF), and it can arise from traumatic and variable non-traumatic events. Rhabdomyolysis-induced ARF is very rare in children. We experienced a case of rhabdomyolysis-induced ARF in a 14-year-old boy who presented with generalized edema and oliguria following trauma, a compressed thigh by a cultivator. Laboratory tests showed marked elevation of muscle...
Original Article
Acute Renal Failure in Children : Underlying Disease and Management according to Age
Eun Joung Park, Joung Sim Kim, Jai Bok Yoo, Joung Sook Sul, Si Whan Koh, Phil Soo Oh, I Suk Kang, Moon Soo Park, Heung Jae Lee, Dong Kyoo Jin
Clin Exp Pediatr. 1998;41(5):654-662.   Published online May 15, 1998
Purpose : It has been stressed that age itself as well as multiple organ failure are important prognostic factors in acute renal failure(ARF) in children. This study was performed to find out the significance of age factor and underlying disease of ARF in children. Methods : We tried to review 58 pediatric ARF cases, retrospectively, in the pediatric intensive care unit(excluding...
Case Report
Acute Renal Failure(ARF) Associated with Yersinia Pseudotuberculosis Infection Diagnosed by Polymerase Chain Reaction
Hyung Gyu Park, Byung Moon Ahn, Eun Ryoung Kim, Il Soo Kim, Jae Jong Kim, Sung Ok Kang, Han Ho Park, Ki Jeong Kim
Clin Exp Pediatr. 1997;40(8):1162-1168.   Published online August 15, 1997
The clinical significance of Yersinia pseudotuberculosis(Y. pseudotuberculosis) has recently recognized in various part of the world because it can cause a wide range of clinical problems such as mesenteric lymphadenitis, septicemia, reactive arthritis, terminal ileitis, erythema nodosum and acute renal failure. we experienced a case of acute renal failure associated with Y. pseudotuberculosis infection. We applied a nested polymerase chain reaction method for rapid diagnosis...
Original Article
A Study of Radiocontrast Media Induced Nephrotoxicit
Chong Guk Lee, Jae Ho Cho, Se Wook Oh, Yong Won Park
Clin Exp Pediatr. 1996;39(4):503-511.   Published online April 15, 1996
Purpose : This study was aimed at determining whether tri-iodinated compounds with greater solubility and low osmolality, Na or meglumine ioxaglate(Hexabrix 320, Guerbet Lab., France) had deleterious effects on renal function after cardiac angiography for the evaluation of congenital heart disease(CHD) and determining whether correction of dehydration using iv hydration given before cardiac angiography were effective in prventing renal dysfunction. Methods...
Acute Renal Failure Following Cardiac Surgery
Kang Yong Park, Yeon Ho Choi, Tae Sun Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Joon Ryang Rho
Clin Exp Pediatr. 1992;35(9):1198-1209.   Published online September 15, 1992
A retrospective study of 452 patients who undertook cardiac surgery was performed to determine the pevalence, etiology, and clinical features of postoperative acute renal failure(ARF). The overall incidence of ARF following cardiac surgery was 4.65%(21/452). The incidence of ARF following open heart surgery(OHS) was 5.11%, and that following closed heart surgery was 2.50%. Preoperactive risk factors noted in the development...
Acute renal failure with back pain after exercise.
Hae Jung Park, Mi Jung Kim, Dong Kyu Jin, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jung Mi Park, Kyung Mo Yeun
Clin Exp Pediatr. 1991;34(6):863-868.   Published online June 30, 1991
We have experienced one case of acute renal failure without clinical rhabdomyolysis characterized by preceding exercise and back pain. This patient showed patch renal increased uptakes in bone scan with 99mTechnetium-methylene diphosphonate, and delayed wedge-shaped contrast enhancements in renal computed tomography. These findings can be explained by focal renal vasoconstriction of interlobar arteries or arcuate arteries, which may be considered as one of the...
Mannitol induced acute oliguric renal failure.
Young Mi Chung, Jae Seung Lee, Chang Jun Coe
Clin Exp Pediatr. 1991;34(6):857-862.   Published online June 30, 1991
Mannitol known as non-electrolytic, osmotic diuretic agent is widely used in clinic for the purpose of diagnosis and prevention of acute oliguric renal failure, cerebral edema as well as glaucoma and dialysis-disequilibrium syndrome. That mannitol may cause serious life-threatening situation if administered in a patient with renal problem has been well known. Recently, it has been published that mannitol may be nephrotoxic in patient...
A Case of Acute Interstitial Nephritis Associated with Yersinia Pseudotuberculosis Infection.
Keun Hee Chung, Yoo Mee Kim, Mee Won Kim, Soon Gi Kim, Moon Soo Park, Jin Keun Chang
Clin Exp Pediatr. 1990;33(8):1123-1128.   Published online August 31, 1990
Authors recently experienced a case of acute interstitial nephritis associated with Yersinia pseudotuberculosis infection in 10-8/12 year old boy, who was admitted to prolonged high fever. On 3rd hospital day, puffy face and oliguria were noted. BUN and serum creatinine rose to peak level, 94.1 mg/dl and 10.1 mg/dl, respectively on 7th hospital day. After then renal functions were normal- ized gradually without specific...
Continuous Arteriovenous Hemofiltration in Children.
Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(2):230-238.   Published online February 28, 1989
Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11 children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year- period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results were as follows; 1) They were 5 boys and 6...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...
Reye's Syndrome in Children.
Dong Jin Lee, Sook Hee Lee, Ja Hoon Koo, Doo Hong Ahn, Yong Jin Kim
Clin Exp Pediatr. 1984;27(5):457-466.   Published online May 31, 1984
A clinical observation has been made on 44 children with Reys's syndrome who were admitted to pediatric department of KNU hospital during 6 year period from September 1977 to August 1983. Male to female ratio was 1.3 : 1. Cases under 6 years of age comprised 40(90.9%) and cases under 1 year 13(29.6%). The most common antecedent illness was URI...
Two Cases of Hemolytic Uremic Syndrome.
Sook Hee Lee, Dong Jin Lee, Ja Hoon Koo, Doo Hong Ahn, Young Jin Kim
Clin Exp Pediatr. 1984;27(4):384-389.   Published online April 30, 1984
The hemolytic uremic syndrome is a clinical state characterized by uremia, thrombocytopenia and microangiopathic hemolytic anemia. Since the first description of this illness by Gasser in 1955, it has been recognized with increasing frequency. Recently, we have experienced 2 cases of severe hemolytic uremic syndrome occurring in boys in 5 and 6 years of age. Diagnosis was established by typical...
Case Report
Korean Hemorrhagic Fever in Children.
Won Seok Lee, Yong Hoon Park, Ja Hoon Koo, Doo Hong Ahn, Yong Jin Kim
Clin Exp Pediatr. 1984;27(3):265-270.   Published online March 31, 1984
Korean hemorrhagic fever is acute febrile illness caused by Hantan virus. It involves capillaries and small vessels systemically, and leads to dysfunctions of many organs, esp. kidney. In recent years, we have experienced 4 cases of korean hemorrhagic fever in children’s age group. Diagnosis was confirmed by immunofluorescent technique in one case and renal biopsy was done in 2 cases....
Original Article
Acute Renal Failure in Children.
Chan Lak Son, Sun Hwan Chung, Yong Hoon Park, Kuhn Soo Lee, Ja Hoon Koo
Clin Exp Pediatr. 1984;27(2):146-155.   Published online February 28, 1984
A clinical study was conducted on 76 children with acute renal failure who had been admitted to the Pediatric Department of Kyungpook National University Hospital during 2.2years period from January 1981 to June 1983, and following results were obtained.Age distribution revealed 19 out of total 76 cases (25%) being infants under 1 year of age and otherwise even distribution was...
Acute Renal Failure due to Mercury Poisoning.
Do Kwang Yun, Jin Yong Lee, Pyung Kil Kim, Chung Suk Kim
Clin Exp Pediatr. 1982;25(8):848-853.   Published online August 31, 1982
One year and 9 month old male baby was admitted to hospital because of burns on the oral cavity and irritability. This symptom developed 3 hours before admission, when he swallowed questionable chemical drug. On admission, physical examination revealed whitish mucosal discoloration on the oral cavity. 3 days after admission, anuric state had been appeared, and general condition has been...
Acute Renal Failure in Children.
Bec Lyul Park, Do Kwang Yoon, Kyung Sook Han, Pyung Kil Kim
Clin Exp Pediatr. 1982;25(2):141-147.   Published online February 28, 1982
We observed 22 cases of acute renal failure in children who were admitted to Severance Hospital from Jan. 1978 till Dec. 1980 and the results are as follows. The acute renal failure was the highest incidence between the age of 6 and 10 years (10 cases out of all), most of whom had acute glomerulonephritis and male was 3.4 times...