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Case Report
Successful treatment by exchange transfusion of a young infant with sodium nitroprusside poisoning
Jong Geun Baek, Hoar Lim Jeong, Ji Sook Park, Ji Hyun Seo, Eun Sil Park, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Hee Shang Youn, Jung Sook Yeom
Clin Exp Pediatr. 2010;53(8):805-808.   Published online August 31, 2010

Although sodium nitroprusside (SNP) is often used in pediatric intensive care units, cyanide toxicity can occur after SNP treatment. To treat SNP-induced cyanide poisoning, antidotes such as amyl nitrite, sodium nitrite, sodium thiosulfate, and hydroxycobalamin should be administered immediately after diagnosis. Here, we report the first case of a very young infant whose SNP-induced cyanide poisoning was successfully treated by...

Review Article
Clinical aspects of injury and acute poisoning in Korean pediatric patients
Joon Seok Park, Mi Jin Lee
Clin Exp Pediatr. 2008;51(2):116-121.   Published online February 15, 2008
Unintentional injuries are the most important cause of morbidity and mortality in the pediatric population, and the home is the most common site of injury for children in Korea. The most common cause of injury was slip down. Fall down and burn were frequent in infant/toddlers group, automobile and bicycle accident more frequent in preschool children. Findings from the survey...
Case Report
Two Cases of Lead Poisoning due to Herb Medicinal Pills
Seong Hwan Choi, Eun Young Park, Jung Yeon Shim, Deok Soo Kim, Jae Won Shim, Hye Lim Jung, Moon Soo Park
Clin Exp Pediatr. 2005;48(9):1009-1015.   Published online September 15, 2005
We encountered two children with lead poisoning who were administered herb medicinal pills recommended by their clergyman. These patients presented anemia and severe coliky abdominal pain, but no neurologic symptoms. For this reason, they were initially misdiagnosed with gastrointestinal hemorrhagic disease. However, we got a clue that they took herb medicinal pills. Finally, based on the assay of blood lead...
Three Cases of Hypercalcemia Due to Vitamin D Intoxication in Infancy
Jin-Ho Choi, Mi-Sun Yum, Hyewon Hahn, Young Seo Park
Clin Exp Pediatr. 2004;47(3):332-337.   Published online March 15, 2004
Hypercalcemia in infancy is an uncommon disorder but has a potential of serious sequelae. Therefore, infants with hypercalcemia must be promptly investigated and need urgent management. We report three cases of infantile hypercalcemia caused by vitamin D intoxication, emphasizing diagnostic investigations and the course of treatment. The first and the second cases were thought to be vitamin D intoxication without...
Original Article
Clinical Study of Childhood Accidents from a Hospital Over Ten Years with Regard to Foreign Body Aspiration
Cheol-Min Kim, Jun-Young Song, Ja Hyung Kim, Ki Soo Kim, Soo-Jong Hong
Clin Exp Pediatr. 2002;45(9):1134-1140.   Published online September 15, 2002
Purpose : Childhood accidents have been increasing recently. Accidents rank as the leading cause of childhood mortality and morbidity. We performed this study to evaluate the causes of childhood accidents. Methods : The authors analysed retrospectively the medical records of 6,410 cases of childhood accidental injuries who visited the emergency room of Asan Medical Center from January 1990 to December...
A Study of Acute Poisoning in Korean Children
Chan Sook Park, Song Hyeun Eun, Mi Hwa Yang, Jin A Son, Jung Yun Hwang, Jae Wook Ko, Don Hee Ahn
Clin Exp Pediatr. 2001;44(6):614-619.   Published online June 15, 2001
Purpose : The National Medical Center has been conducting a study as a Poison Control Center since 1998. The data was analyzed to illustrate the general aspects of acute poisoning in Korean children. Methods : The primary sources of data were collected from the Medical Insurance Records of 1997 and death records of the same period obtained from the Korea National Statistical Office. A total...
The Statistical Study of Patient with Acute Poisoning
Heung Pyo Kong, Kyoung Bae Park, Oh Kyung Lee, Kang Suh Park
Clin Exp Pediatr. 1997;40(11):1596-1602.   Published online November 15, 1997
Purpose : The incidence of infectious disease, which has been the cause of death in pediatric period, was decreased. But, the opportunistic exposure to toxic substance shows a tendency to increase. We performed this study in order to find out preventive measures and the latest inclination of acute poisoning in childhood. Methods : From January 1985 to July 1996, 88 children with acute drug...
The Clinical Study of Acute Poisoning in Children
Dae Kun Kim, Ki Cheol Choi, Eun Kyung Jung, Eun Seok Yang, Kyung Rye Moon
Clin Exp Pediatr. 1996;39(12):1753-1758.   Published online December 15, 1996
Purpose : Poisoning represents one of the most common accidents encountered by young children. Recently, mortality due to poisoning has gradually decreased, but the incidence has not decreased. We performed this study to compare the following factors during 1980's and 1990's : sex distribution, urban and rural distribution, causative substances. Methods : A clinical study was performed on 90 cases of acute poisoning who...
Case Report
A Case of Acute Tubular Necrosis Induced by paraquat (Gramoxon®) Intoxication
Young Guk Kim, Dong Gun Park, Kee Hwan You, Keun Haeng Cho, Young Sook Hong, Soon Kyum Kim
Clin Exp Pediatr. 1994;37(8):1143-1148.   Published online August 15, 1994
Paraquat (1, 1'-dimethy1-4, 4'dipyridium chlorde: Gramoxon￠c) was first discovered in England in 1955. It has been widely distributed for use in Korea since 1970 as a pesticide and also often the cause of accidental intoxications. The authors would like to report the following case of paraquat intoxication in a 13 year old female child admitted via emergency room with complaints...
A Case of Lead Poisoning
Mee Kyung Jang, Kuk Sin Jang, Young Chul Han, Dong Gui Jang, Chul Ju Jung
Clin Exp Pediatr. 1992;35(9):1286-1290.   Published online September 15, 1992
The lead poisoning has been increasingly recongized in Korea The sources of lead poisoning are several ones such as from occupation, painting house, ccsmetics, diet, abnormal habits(Pica), occasionally herb medicine in Korea. Recently, we experienced a case of lead poisoning, in a 19-month-old female who ered from vomiting and acute abdominal pain. Clinical aspects, laboratory test, hematological and special biochemical tests were...
Original Article
A Study on Pratol(R) Poisoning in Childhood.
Hyon Sook Seo, Heock Il Kwon, Jae Seung Lee
Clin Exp Pediatr. 1990;33(3):299-305.   Published online March 31, 1990
A Clinical observation was made on 22 cases of Pratol poisoning in childhood, who were admitted to department of pediatrics, severance hospital from January, 1979 to June, 1989. The results were as follows: 1) The ratio of male to female was 1:1 in total, 7 cases: 3 cases in the age group of 1 to 3 year and 3 cases: 7 cases in the age...
A case of paraquat poisoning in child.
Min Yong Oum, Sung Ik Cho, Young Chang Kim, Hak Ju Cha, Sang Jhoo Lee
Clin Exp Pediatr. 1989;32(11):1540-1545.   Published online November 30, 1989
Paraquat is a widely used herbicide and its poisoning in human induces acute renal failure, hepatic dysfunction, progressive respiratory failure, oral cavity ulcer and cardiac manifestations with high mortality rate. We experienced a case of paraquat poisoning in a 12 years old child who revealed acute renal failure, pneumothorax, subcutaneous emphysema, pneumomediastinum and died 44 hours at acciden- tal ingestion of paraquat solution inspite of...
The Clinical study of Acute Poisoning in Children.
Ji Ho Song, Sang Young Chung, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1331-1336.   Published online October 31, 1989
A clinical study was performed on 145 cases of acute poisoning who were admitted in pediatric department of Kyung Hee University Hospital during the past 15 years from Jan. 1973 to Dec. 1987. The results are as follows; 1) There was no significant annual differences in frequency of poisoning, and the peak incindence in a year was in April and July (12.4%). 2) The sex ratio of...
Paraquat Poisoning.
Soo Yup Lee, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(8):891-900.   Published online August 31, 1987
Paraquat is a widely used herbicide and in human its poisoning induces acute renal failure, hepatic dysfunction, progressive respiratory failure, and oral cavity ulcer etc. with high mortality rate of 30-70%. The authors analyzed twenty-one cases of paraquat poisoning who were admitted at Hanyang University Hospital from May, 1972 to December, 1986 and the results were as followings. 1) Among 21 cases, 11 cases were...
Case Report
Clinical & Animal experimental observation on the Botulism Poisonig in a Family.
Yeong Du Lee, Yang Weon Lee, Jae Ho Lee, Yong Hun Chung
Clin Exp Pediatr. 1985;28(9):906-911.   Published online September 30, 1985
Five patients in a family were admitted to the department of peditrics and medicine, CNUH on July 17th, 1984 because of respiratory arrest after ingestion of the rotten sausage. All four children of five patients were expired, but only adult patient was recovered completely. Epidemiological outbreak, clinical course and animal toxin challenge test were compatible with botulism poisoning.
Original Article
A Clinical Observation of Acute Carbon Monoxide Poisoning.
M R Roh, K W Lee, E M Kim, S M Shin, S J Lee
Clin Exp Pediatr. 1984;27(12):1213-1217.   Published online December 31, 1984
Carbon monoxide poisoning is one of the most serious public health problem in Korea. Author analysed 126 cases of pediatric CO poisoning which had been treated in emergency room of Soon Chun Hyang Hospital, during 4 years from Jan. 1979 to Decern. 1983. The results are as follows: 1) Incidence in male was similar to that in female and the age group between 11 〜...
Case Report
Acute isoniazid poisoning in childhood.
Ji Tae Choung, Jun Tae Park, Jee Kyu Lee, Kyu Eun Lee
Clin Exp Pediatr. 1982;25(9):959-962.   Published online September 30, 1982
Sin:e tae introiucdon of isoniazid in ；1952, periodic reports of intentional or accidental intoxications complicate! by generalize! convulsions have appeared. Only 31 cases, to our knowlelge, have reportei in English literature until 1980 in pediatric age group. In Korea, oily two cases of a?ite isoniazid intoxication in childhood reported, although there are high incideiee of T.B. ani frequent use of isoniazid. We have experienced...
Original Article
Acute Renal Failure due to Mercury Poisoning.
Do Kwang Yun, Jin Yong Lee, Pyung Kil Kim, Chung Suk Kim
Clin Exp Pediatr. 1982;25(8):848-853.   Published online August 31, 1982
One year and 9 month old male baby was admitted to hospital because of burns on the oral cavity and irritability. This symptom developed 3 hours before admission, when he swallowed questionable chemical drug. On admission, physical examination revealed whitish mucosal discoloration on the oral cavity. 3 days after admission, anuric state had been appeared, and general condition has been...
Clinical Analysis on Accident of Children.
Kyung Sik Shin, Sang Hyun Byun, Kwang Joo Rhee, Suk Ja Kim, Young Hun Chung
Clin Exp Pediatr. 1982;25(8):829-838.   Published online August 31, 1982
There has been a significant decline of infectious disease in childhood due to an improvement of economy, living standard and medicine. But accidents in childhood is rather increased and encountered in major cause of death. The child is not so fully developed mentally and physically, that he is vulnerable to accident. Most accidents have been rocognized as being preventable with...
Case Report
A Case Report of Ginko Biliba Linne Friuts Juice Intoxication.
Sook Kyung Yoon, Jun Taek Park, Chang Hee Choi, Kyu Eun Lee
Clin Exp Pediatr. 1982;25(4):416-418.   Published online April 30, 1982
A Case of acute Ginko poisoning in a Year and 1 month old girl was presented. The patient was admitted, with chief complainsof abrupt vomiting, general clonic convulson and unconsciouseness, which was developed 2 hours after ingestion of Ginko biloba L.. There was revealed leukocytosis, increased C.S.F. pressure with positive Babinski sign. This patient was treated with anticonvulsants, antipyretics, steroid...
Original Article
Clinical Observation on Accidents for Infant and Childhood Who Visited the Emergency Room in the Wonju Christian Hospital from Kangwon Area.
Seong Ku Kim, Duk Jin Yun
Clin Exp Pediatr. 1981;24(10):957-967.   Published online October 15, 1981
Accidents have become one of the most important problem in the pediatric and child health field because of the recently observed high incidence of and mortality from accidents. Due to an improvement of the living standard in general and especially due to the wide application of vaccination and antibiotics, there has been a decline of incidence of infectious diseases in...