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Original Article
Parental concerns about their premature infants' health after discharge from the neonatal intensive care unit: a questionnaire survey for anticipated guidance in a neonatal follow-up clinic
Ji-Yun Cho, Juyoung Lee, Young Ah Youn, Soon Ju Kim, So Young Kim, In Kyung Sung
Clin Exp Pediatr. 2012;55(8):272-279.   Published online August 23, 2012
Purpose

The aim of this study was to develop an appropriate nursing information guideline according to corrected age, after investigating parents' concerns about the growth, development, and diseases of their premature infants after discharge from the neonatal intensive care unit (NICU).

Methods

The parents of premature infants (birth weight, <2,500 g; gestational age, <37 weeks) who went to a neonatal follow-up clinic after...

Case Report
Masticator space abscess in a 47-day-old infant
Eunhee Kim, Ju Hee Jeon, Yoon Hee Shim, Kyu-Seok Lee, So Young Kim, Eun Ryoung Kim
Clin Exp Pediatr. 2011;54(8):350-353.   Published online August 31, 2011

A 47-day-old male infant presented with fever, poor oral intake, irritability, and right-sided bluish buccal swelling. Contrast-enhanced computed tomography of the neck showed a round mass lesion of about 2.0×1.5 cm that suggested abscess formation in the right masticator space. Ultrasound-guided extraoral aspiration of the abscess at the right masseter muscle was successful. Staphylococcus aureus was identified in the culture...

Review Article
Neonatal respiratory distress: recent progress in understanding pathogenesis and treatment outcomes
So Young Kim
Clin Exp Pediatr. 2010;53(1):1-6.   Published online January 15, 2010
Transient tachypnea of the newborn (TTN), respiratory distress syndrome (RDS), and persistent pulmonary hypertension (PPHN) are the three most common disorders that cause respiratory distress after birth. An understanding of the pathophysiology of these disorders and the development of effective therapeutic strategies is required to control these conditions. Here, we review recent papers on the pathogenesis and treatment of neonatal...
Original Article
Correlaton between soluble transferrin receptor concentration and inflammatory markers
So Young Kim, Meong Hi Son, Jung suk Yeom, Ji sook Park, Eun Sil Park, Ji-Hyun Seo, Jae-Young Lim, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn
Clin Exp Pediatr. 2009;52(4):435-440.   Published online April 15, 2009
Purpose : The concentration of soluble transferrin receptor (sTfR) is estimated as an iron parameter to evaluate erythropoiesis and iron status. The aim of our study is to evaluate the correlation between sTfR concentration and inflammatory parameters and to distinguish iron deficiency anemia from anemia of inflammation. Methods : One hundred and forty-four infants younger than two years of age who...
A rise and fall in AST and ALT level in nonspecific reactive hepatitis
Tai Sung Kim, Tae Hyung Hur, Sun Jeong Lim, Joong Hyun Bin, Seung Hoon Hahn, So Young Kim, Hyun Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2008;51(4):396-400.   Published online April 15, 2008
Purpose : The study was performed to assess the distribution of the diseases associated with nonspecific reactive hepatitis (NRH) for the past 10 years and to evaluate the change in the level of AST and ALT, and the difference by several variable factors. Methods : From January 1997 to December 2006, 646 patients had elevated liver enzymes among 22,763 patients admitted...
Quantification of endothelin-1 in human umbilical venous endothelial cell culture supernatants of small for gestational age and preeclampsia neonates
Won Kyoung Cho, So Young Kim, Chung Sik Chun
Clin Exp Pediatr. 2007;50(12):1194-1199.   Published online December 15, 2007
Purpose : It was generally accepted now a days that the pathogenesis of preeclampsia, small for gestational age (SGA), intrauterine growth retardation and fetal origin of adult diseases were related with a endothelial cell dysfunction. The purpose of this study was to know the relation of such diseases by assessing the level of endothelin-1. Methods : SGA babies, newborns of...
Normal antistreptolysin O titers of children by age group in the Gyeonggi-Incheon region
Jihun Lee, Yoo Jung Kim, Joong Hyun Bin, Ja Young Hwang, Seong Hoon Hahn, So Young Kim, Hyun Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2007;50(10):965-969.   Published online October 15, 2007
Purpose : Measurement of antistreptolysin O (ASO) is often necessary to confirm a clinical diagnosis of recent streptococcal infection, especially in patients suspected of rheumatic fever and acute glomerulonephritis. Standard normal ranges for ASO should be established locally for each age group. We analyzed ASO to determine the upper limit of normal (ULN) ASO in children in the Gyeonggi-Incheon area. Methods...
Detection of Cytokeratin-19 caused by Intestinal Epithelial Cell Damage in Childhood Diarrhea
Ja Young Hwang, Se Young Seo, Seong Hoon Hahn, So Young Kim, Hyun Hee Kim, Won-Bae Lee
Clin Exp Pediatr. 2004;47(11):1193-1197.   Published online November 15, 2004
Purpose : Acute gastroenteritis in infancy is a very common disease with a frequency of a billion diarrhea per year, leading to 3 to 5 million deaths. Since the etiology is not always clear, the treatment plan can be quite difficult to make. The laboratory examinations of stool culture, along with complete blood counts may sometimes be helpful to find...
Comparison of Cytokine Expressions among Kawasaki Disease and Its Symptom-related Diseases
Ran Lee, So Hyun Park, Yu Jeong Kim, So Young Kim, Hyun Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2004;47(5):567-573.   Published online May 15, 2004
Purpose : Kawasaki disease(KD) is an important acute febrile systemic vasculitis disease. Various cytokines have been studied to evaluate the pathogenesis of vascular injury. Some cytokines have been implicated for vascular injury, but there has been no direct evidence. We compared cytokine profiles of KD with Henoch-Sch nlein purpura(HSP), and febrile infections. Methods : We investigated the serum concentrations of...
Effects of Insulin-like Growth Factor-I and 1,25-(OH)2 Vitamin D3 Concentration on Intrauterine Growth of Newborns from Mothers with Preeclampsia
In Sook Yang, Jung Hyun Lee, Hyung Shin Lee, So Young Kim, Sung Dong Choi, In Kyung Sung, Chung Sik Chun
Clin Exp Pediatr. 2004;47(5):527-531.   Published online May 15, 2004
Purpose : This study was undertaken to observe the blood levels of IGF-I and 1,25-(OH)2 Vit. D3 in maternal and neonatal compartments and the effects of IGF-I concentration on intrauterine fetal growth and 1,25-(OH)2 Vit. D3 metabolism in the presence of preeclampsia. Methods : Thirty-four full-term pregnant women with preeclampsia and their newborns(preeclampsia group) and 10 normotensive full-term pregnant women and...
Case Report
A Case of G-6-PD Guadalajara
Gi Bum Lee, Sun Ju Lee, Yoo Jung Kim, So Young Kim, Hyun Hee Kim, Bin Cho, Wonbae Lee
Clin Exp Pediatr. 2004;47(2):210-213.   Published online February 15, 2004
Glucose-6-phosphate dehydrogenase(G-6-PD) deficiency is a disease that shows hemolytic anemia and jaundice caused by injury of erythrocytes. The gene of G-6-PD has 13 exons and locates in Xq28, and over 150 mutations of this gene have been reported. We experienced a G-6-PD deficienct male patient who was suffering hemolytic anemia and jaundice confirmed by measuring low G-6-PD activity in the...
Original Article
Plasma G-CSF and GM-CSF Concentrations and Expression of their Receptors on the Granulocyte in Children with Leukocytosis
Won Seok Choi, Kyung Hwan Ryu, You Jeong Kim, So Young Kim, Hyun Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2003;46(3):271-276.   Published online March 15, 2003
Purpose : Granulocyte-colony stimulating factor(G-CSF) and granulocyte macrophage-colony stimulating factor(GM-CSF) are principal cytokines in granulopoiesis and their physiologic effects are mediated through binding to specific cell surface receptors. Although it is known that the level of serum G-CSF and GM-CSF, and presentation of the receptors are increased in infectious diseases, there have been no studies to find the correlation between...
Case Report
A Case of Congenital Solitary Liver Abscess
Sang Hee Kim, So Young Kim, You Jeong Kim, Hyun Hee Kim, Won Bae Lee, Kyung Tai Whang
Clin Exp Pediatr. 2002;45(11):1426-1429.   Published online November 15, 2002
Congenital solitary liver abscess in newborns is an extremely rare and serious disease. Only one case was reported in the literature. Most a liver abscesses have a postnatal origin. We encountered a premature infant who had a low. Apgar score and an elevated right diaphragm at birth. Pyogenic solitary liver abscess was diagnosed by ultrasound and computed tomography. Staphylococcus aureus...
Original Article
Comparison of Acute Clinical Features and Coronary Involvement in Patients with Kawasaki Disease between Those Younger and Older than One Year of Age
So Young Kim, Seong Joon Lim, Sin Weon Yun, Dong Keun Lee, Eung Sang Choi
Clin Exp Pediatr. 2002;45(6):773-782.   Published online June 15, 2002
Purpose : To identify the necessity of more reasonable diagnostic criteria and the possibility of early prediction of coronary involvement in the higher risk group, we investigated and compared clinical and laboratory findings in the acute phase and coronary involvements in those younger (n=17) and older(n=53) than one year of age in Kawasaki disease(KD). Methods : Retrospective chart reviews were performed...
Case Report
Two Cases of Hydrometrocolpos in Neonate
Min Young Park, Bo Ra Son, So Young Kim, Young You Kim, Hyun Hee Kim, Won-Bae Lee, In Kyung Sung, Chung Sik Chun, Su Aa Lim
Clin Exp Pediatr. 2002;45(2):278-283.   Published online February 15, 2002
Imperforated hymen, vaginal atresia or high transverse vaginal septum are caused by incomplete vaginal canalization. The infant may be present with distention of the vagina and the uterus with glandular secretions stimulated by maternal estrogens, known as hydrometrocolpos. We report two cases of hydrometrocolpos. In the first case, distal vaginal atresia with cystovaginal fistula was revealed by a contrast fluoroscope...
Medical Lecture Course
Transcriptional Regulation of Type I Alveolar Epithelial RTI40 Gene in the Lung
So Young Kim
Clin Exp Pediatr. 2001;44(3):260-265.   Published online March 15, 2001
Original Article
Detection Limit of Minimal Residual Disease in Leukemia Using Fluorescence in situ Hybridization
Jung Hyun Lee, So Young Kim, Hyun Hee Kim, Byung Kyu Suh, Wonbae Lee, Kyung Tai Whang
Clin Exp Pediatr. 2000;43(10):1364-1371.   Published online October 15, 2000
Purpose : The close relationship between the size of a tumor burden and the curability of acute leukemia is well established. Therefore, it is very important to detect residual leukemia accurately at low levels. Fluorescence in situ hybridization(FISH) techniques rely on chromosome-specific and gene specific DNA probes to identify numerical and structural chromosomal abnormalities. But the detection limit of FISH...
Antineutrophil Cytoplasmic Antibody in Kawasaki Disease
Soh-Yeon Kim, So Young Kim, Wonbae Lee, Kyong Su Lee, Ji-Min Kang
Clin Exp Pediatr. 1998;41(6):808-812.   Published online June 15, 1998
Purpose : Antineutrophil cytoplasmic antibody(ANCA) has been identified in various disorders including Wegener' s granulomatosis, microscopic polyarteritis and Kawasaki disease. Measuring this antibody has a diagnostic role. It facilitates monitoring disease activity and may also help understand the pathogenesis of the diseases in which it is found. We investigated the correlation between the hematologic findings and ANCA in acute Kawasaki disease and the diagnostic potential...
Case Report
A Case of Arthrogryposis Multiplex Congenita with Congenital Hypertropic Pyloric Stenosis
Seung Chul Yang, So Young Kim, Hyun Hi Kim, Seung Hoon Han, Jong In Byun, Won Bae Lee
Clin Exp Pediatr. 1995;38(11):1577-1582.   Published online November 15, 1995
Arthrogryposis multiplex congenita is a congenital syndrome characterized by extreme stiffness and contracture of multiple joints and associated hypoplasia or absence of development of muscle, bone, and soft tissues; and refers to a heterogeneous group of congenital disorders of unknown but probably multiple etiologies. We present a 50 days old male baby who has had mmultiple fixed contractures of joints...
Original Article
Use of Fluorescent in Situ Hybridization to Evaluate the Number of Chromosomes in Buccal Smear Cells in Normal Newborn Infants
Byoung Chan Lee, Jee Yeon Song, So Young Kim, Hyun Hee Kim, Seunghoon Han, Jong-In Byun, Wonbae Lee, Kyong Su Lee
Clin Exp Pediatr. 1995;38(11):1470-1475.   Published online November 15, 1995
Purpose : The diagnosis for chromosomal anomality has been made by obtaining cells in metaphase from peripheral blood and fresh tissue culture. But this method is difficult to perform because somewhat invasive and necessary time for cell culture and staining(48-72hr). Recently, the method to find numerical abnormalities in, autosome and sex chromosome of adult buccal mucosal smear by FISH was...
Case Report
Acute Disseminated Encephalomyelitis
So Young Kim, Jong Woo Bae, Byung Churl Lee
Clin Exp Pediatr. 1992;35(5):671-677.   Published online May 15, 1992
Acute disseminated encephalomyelitis is an uncommon immune mediated inflammatory disorder of the central nervous system. It may be defined as a monophasic encephalitis or myelitis of abrupt onset characterized by symptoms and signs indicative of damage chiefly of the white matter of the brain or spinal cord. The process may be severe and even fatal or mild and evanescent. The...
Subacute Necrotizing Encephalomyelopathy (=Leight's Disease)
So Young Kim, Heung Ki Min, Byung Churl Lee
Clin Exp Pediatr. 1992;35(3):395-398.   Published online March 15, 1992
Subacute necrotizing encephalomyelopathy or Leigh's disease is a familial neurodegenerative disorder characterized by focal bilateral and usually symmetric lesions of both gray and white matter in the brain and the spinal cord. The lesions are strikingly similar to those of thiamine deficiency encephalopathy. The diagnosis of subacute necrotizing encephalomyelopathy was usually made by typical clinical manifestation and typical bran CT...