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Original Article
Two Cases of Allergic Rhinitis in Children Diagnosed by Youlten's Peak Nasal Inspiratory Flow (PNIF) Meter.
Yil Sub Lee, In Suck Ryu, Kyu Eun Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(11):1527-1532.   Published online November 30, 1988
Two asthmatic children associated with allergic rhinitis were performed nasal provocation test with various allergens which were detected by allergic skin test. The degree of nasal obstruction induced by allergens were measured with Youlten’s Peak Nasal Inspiratory Flow (PNIF) meter and Red top,Trichophyton and Sagebrush were known as causative allergens in case 1, and Chrysanthemum was detected as causative allergen in case 2. The...
Clinical Evaluation of Children with Psychiatric Problems Among Pediatric Patients.
Woo Tae Kim, Chan Yung Kim
Clin Exp Pediatr. 1988;31(9):1183-1192.   Published online September 30, 1988
The author has analysed 1080 cases of Pediatric patients visited Pediatric or psychiatric depart- ment for behavioral, emotional, or Psychiatric problems, from July 1982 to June 1987. The patients were categorized into three groups to observe the distribution of age, sex and disease, and the relation of symptom and disease, 127 cases consulted to Psychiatric department, 356 cases visited Psychiatric department directly, and 597...
Lipoproteinelectropheresis pattern in Nephrotic Syndrome.
Soon Don Hong, Byung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1988;31(9):1163-1170.   Published online September 30, 1988
This study was undertaken to eluidate lipoprotein patterns in patients with childhood nephrotic syndrome by response to initial steroid therapy, serum albumin level in MCNS and other histologic classifications. The result were summerized as follows. 1) There were 19 cases (52.8%) of abnormal lipoprotein patterns by Fredrickson classifications, type Ila were 6 cases (16.7%), type lib were 1 cases (2.8%) and type IV were 12 cases...
A Case of Iron Deficiency Anemia with Hypoproteinemia.
Seong Ho Kim, Woo Kill Lee
Clin Exp Pediatr. 1988;31(8):1054-1058.   Published online August 31, 1988
Severe iron deficiency anemia is occasionally accompanied by hypoproteinemia and edema. There is evidence that the hypoproteinemia is caused by increased intestinal loss of serum protein. We experienced a case, 1 year and 6 months old female patient with generalized edema, diagnosed as iron deficiency anemia with hypoproteinemia. After treatment with ferrous iron preparation, generalized edema was subsided, and hemoglobin value and serum protein...
A Prospective Study of Urinary beta2 -Microglobulin in Infants with Meconium-Stained Amniotic Fluid.
Sung Oh Kim, Jeh Hoon Shin, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1988;31(8):968-976.   Published online August 31, 1988
We studied prospectively whether events that result in meconium staining may be associated with additional abnormalities that are not clinically apparent associated by measurements of urinary concentrations of β₂-microglobulin indicating renal proximal tubular functions. Among 61 fullterm, healthy neonates delivered at Hanyang University Hospital during the period of September 1986 through April 1987, urinary concentration of β₂-microglobulin and creatinine were measured during the immediate perinatal...
Present status and Problems of weaning.
Young Le Yoon, Moon Hae Bang, Hong Kee Bang, Gang Il Lee, Hak Joo Cha, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1988;31(7):863-872.   Published online July 31, 1988
This study was conducted to find out the present status and problems of weaning in the provinces of Korea with the 578 outpatients who visited Chun-An, Ku-Mi and Eum-Sung Soon Chun Hyang University Hospital from November 1986 to June 1987. The results and problems obtained from the study are summerized as follows 1) Among 578 parents of this study, 173 were from country and 405...
Treatment of Acute Myelogenous Leukemia in Children: Remission Induction with Adriamycin and Cytosine Arabinoside, and Postremission Maintenance Chemotherapy with Adriamycin, Cytosine Arabinoside and 6-thioguanine.
Soon Ki Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):850-862.   Published online July 31, 1988
The authers assessed the effectiveness of chemotherapy in 40 children with AML, experienced at Seoul National University Children’s Hospital during 8 years 5 months from April 1979 to August 1987. Remission induction treatment included adriamycin 30 mg/m2/day IV on days 1-3 and cytosine arabinoside 75 mg/m2/day continuous IV infusion on days 1-5. This regimen was repeated, if necessary, for one or two more courses. After...
A Case of Myositis Ossificans Progressiva.
Yoeng Ho Ra, Sung Ho Cha, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):271-275.   Published online February 28, 1988
A cases of Myositis ossificans progressiva in a 3 year-old girl who presented with hard mass in her right buttock and progressive hardening of muscles of her back and neck. The diagnosis was made on the basis of typical clinical features and characeristic radiologic findings. In addition to the cases report, a review of related literatures were discussed.
Factors Influencing the Prognosis of Reye Syndrome.
Chang Ho Hong, Heung Dong Kim, Pyung Kil Kim
Clin Exp Pediatr. 1987;30(11):1252-1258.   Published online November 30, 1987
While the etiology of Reye syndrome is still unknown, wide variations in both the clinical spectrum and the therapeutic outcome of patients have been noted. We reviewed the cases of 42 Reye syndrome patients who were admitted to Young Dong Severance Hospital during the period from April, 1983 to July, 1986 and analyzed factors influencing the prognosis of Reye syndrome. The patients were divided...
Clinical Observation and Study for Cerebrospinal Fluid Protein Levels in Aseptic Meningitis.
D H Chee, M I Lee, S H Kim, K C Sohn
Clin Exp Pediatr. 1987;30(10):1107-1114.   Published online October 31, 1987
Observation for clinical findings and laboratory findings, especially for cerebrosipinal fluid protein level has been done in 57 cases of aseptic meningitis who had been admitted to pediatric dept, of National Medical Center from Jan. ’81 to May ’85. The results were as follows; 1) The ratio of male to female was 1.7:1, and the cases were distributed relatively evenly through ...
Syndrome of Inappropriate Secretion of Antidiuretic Hormone(SIADH) in Acute Respiratory Diseases.
Young Jee KIm, Young Yull Koh, Jeong Kee Seo, Hung Ko Moon
Clin Exp Pediatr. 1987;30(9):1021-1028.   Published online September 30, 1987
The SIADH incidence and relevant factors in acute respiratory diseases were evaluated in 461 children with over 28 days old, hospitalized for bronchiolitis, viral pneumonia, bacterial pneumonia, mycoplasma pneumonia and asthma, without other causes of electrolyte imbalance. The overall incidence of SIADH in acute respiratory diseases was 11.93%. The incidence in mycoplasma pneumonia (19.05%) was highest and incidence in bacterial pneumonia (17.42%), viral pneumonia (9.17%),...
Clinical Value of Urinary β₂ -Microglobulin in Patients with Urianry Tract Infection.
Nak Uk Sung, Chang Ryul Kim, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(9):1014-1020.   Published online September 30, 1987
Urinary tract infection (UTI) in children is relatively common infectious disease and it may be the forerunner of severe renal diseases in adulthood. The site of infection is an important factor in the evaluation of the clinical course, treatment and prognosis of patients with UTI, because patients with bacteriuria of renal origin (pyelonephritis) are probably at risk of developing the renal parenchymal reduction seen...
Clinico-Epidemiological Study on Leprosy Patients in Children.
Koo Jeoung Jung, Byoung Soo Cho, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn, Do Seo Koo, Do Il Kim
Clin Exp Pediatr. 1987;30(7):769-776.   Published online July 31, 1987
Clinico-epidemiological study on 44 patients with leprosy in less than 20-year-old children visited to Institute for Leprosy Research, Korean Leprosy Control Association during past 9 years from January, 1978, to August, 1986 was carried out and the following results were obtained. 1) Age at time of visit was shown peak in the age group of 16-20 years (34 cases, 77%), but non in the age...
Case Report
A Case of Holoprosencephaly.
Byung Chun Suh, Soon Sup Jang, In Joon Seol, Soo Jee Moon, Chong Moo Park, Seok Chol Jeon
Clin Exp Pediatr. 1987;30(6):695-700.   Published online June 30, 1987
We experienced a case of holoprosencephaly with extracranial abnormalities, including orbital hypotelorism, median cleft lip without philtrum, flat nasal bridge, flat face, and microcephaly and with a karyotype, 46 XX, 22p+. The diagnosis was confirmed by brain CT scan & brain ultrasonography, and the findings were compatible with an alobar type of holoprosencephaly. The patients died at 26 days of age. A brief review of...
Original Article
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
A Survey of the Outcome of Childhood Asthma.
Hyung Ja Park, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1987;30(1):55-63.   Published online January 31, 1987
An outcome of 416 children who was diagnosed and treated for bronchial asthma at pediatric department of National Medical Center from 1965 to 1984 was surveyed using return postcard. The following results were obtained. 1) We mailed 416 cards and 74 cards (17.8%) were returned. 2) 37.8% of the patients had been entirely asymptomatic for a year or more and 32.5% improved. 22.9% of the patients...
Herpes Zoster in Children.
Soon Ki Kim, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1986;29(12):1324-1333.   Published online December 31, 1986
Herpes zoster, an inflammatory human disease caused by varicella-zoster virus, is characterized by papulovesicular lesions along the distribution of a sensory nerve. Herpes zoster infection, known to be benign in normal children, is more frequent and severe in immunosuppressed patients and is associated primarily with increased morbidity rather than mortality. We analysed retrospectively the clinical manifestations of herpes zoster infections...
Case Report
A Case of Hutchinson-Gilford Progeria Syndrome.
Byeung Ju Jeoung, Duk Hi Kim
Clin Exp Pediatr. 1986;29(10):1138-1142.   Published online October 31, 1986
Recently, the authers experienced a case of Hutchinson-Gilford Progeria sydrome which is characterized by stunded growth, premature aging and normal intelligence. They die prematurely as a results of myocardial infarction with on average age of 13. Berief review of the literatures was made.
Original Article
Cord Plasma Alpha-Fetoprotein Values and Neonatal Jaundice.
Mee Kyung Namgoong, Sei Hee Choi, Ae Sook Kim, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1986;29(8):836-839.   Published online August 31, 1986
Alpha-fetoprotein(aFP) levels were studied in 20 neonatally hyperbilirubinemic children and 20 controls matched for gestational age. The mean aFP value of cord blood (119+58.2산g/ml) with hyperbilirubinemic children was significantly greater than that(79.6±40.8/zg/ml) for the control infants(P<0.001). At the age of 3 and 5 days the mean serum aFP in hyperbilirubinemic children were higher compared with the control group, the difference...
Idiopathic IgA Nepropathy in Children.
Hae Il Cheong, Han Wook Yoo, Kwang Wook Ko
Clin Exp Pediatr. 1986;29(6):633-643.   Published online June 30, 1986
We analyzed clinical findings, pathological findings and clinico-pathological correlations in 55 children with idiopathic IgA nephropathy confirmed immunopathologically, and the results were as follows; 1) The mean age at onset was 9.65±2.45 years with relatively even distribution in school ages and males outnumbered females by 1.75 : 1. 2) The main mode of presentation was typical...
Case Report
A case of Hutchinson Gilford Progeria Syndrome.
Myung Ho Cho, Yong Woo Choi, Wan Seob Kim, Oh Kyung Lee, Myung Ho Lee
Clin Exp Pediatr. 1986;29(5):570-574.   Published online May 31, 1986
An extremely rare syndrome originally described by Hutchinson in 1886 and Gilford in 1904 is associated with a characteristic aged appearance very early in life. Although numerous clinical. metabolic and pathologic studies had been carried out and several theories advanced , the cause and pathogenesis of progeria remain obscure. The patient of this syndrome develope widespread atherosclerosis and often...
Original Article
Progostic Factors in Neonatal Asphyxia.
Hye Li Chung, Wan Sup Kwak, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1986;29(4):420-425.   Published online April 30, 1986
A clinical study was conducted on 30 term babies with neonatal asphyxia, who were admitted to Pediatric Department of Kyungpook National University Hospital during 2years period from May 1983 to April 1985. Of the 20 cases returned to follow up, 15 cases were neurodevelopmentally normal but 5 cases were retarded with neurologic disability. Retarded case revealed higher incidence of severe asphyxia...
Study on Clinical Findings and Histopathologic Types in Biopsy Proven Glomerular Diseases in Korean Children.
Jae Seung Lee, Young Cherl Lee, Pyung Kil Kim, Hyeon Joo Jeong, In Joon Choi
Clin Exp Pediatr. 1986;29(2):143-151.   Published online February 28, 1986
A clinical and pathologic study was made on 360 cases of renal biopsies in children who were admitted to Severance Hospital, Yonsei University College of Medicine, from Jan. 1979 to Dec. 1984. 1) Among 360 cases, 250 cases were male and 110 cases were female. The sex ratio of male and female was 2.3 : 1. The distribution was from 1 6/12...
A Study on Changes of Serum Prootein, Immunoglobulins, and Electrolyte Metabolism in Childhood Nephrotic Syndrome after Steroid Therapy.
Kyung Rae Moon, Chang Soo Ra
Clin Exp Pediatr. 1986;29(1):32-44.   Published online January 31, 1986
The author determined serum and 24hr urine protein(total protein and albumin), immunoglobulins(lgG, IgA, and IgM) and serum electrolytes(Na, K, Ca, P, Mg, and Cl) in 5 cases of childhood nephrotic syndrome before and after steroid therapy, until urinary excretion of protein was negative (remission).The results observed are summarized as follows; 1) Serum protein; Before treatment, the mean serum total protein...
Case Report
4 Cases of Progressive Muscular Dystrophy.
Jung Hee Kim, Dong Wook Kim, Dae Deok Ahn, Jung Kwon Lee, Yoon Ja Kim
Clin Exp Pediatr. 1985;28(12):1225-1230.   Published online December 31, 1985
Progressive muscular dystropy is a genetically determined disorder characterized by-progressive weakness and wasting of skeletal muscles. The etiology of muscular dystropy is unknown, and no form of phamacological treatment is considered effective. The authors report 4 cases of P.M.D., of which 2 cases occured in a family and 2 cases were developed sporadically. They were diagnosed by clinical findings, serum,...
Original Article
Prognosis of Complete Transposition on the great Arteries.
Jung Yun Choi, Soon Ung Kang, Son Moon Shin, Chung il Noh, Yong Soo Yun, Chang Yes Hong, Joon Ryan Rho, Chong Whan Kim, Kyung Phill Suh
Clin Exp Pediatr. 1985;28(12):1177-1183.   Published online December 31, 1985
Sixty five cases of complete transposition of the great arteries were diagnosed at Seoul National University Hospital from August 1980 to August 1984. Among them, 44 cases visited our hospital before 1 year of age and 21 cases after 1 year of age. Sex ratio was 3.3 : 1. Type III (with ventricular septal defect) was more prevalent in our...
Effects of Antenatal Indomethacin on Neonate.
Ja Ye Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1985;28(11):1066-1072.   Published online November 30, 1985
Prostaglandins play an important role in mediating uterine contractions and thus may also be involved in the triggering of premature labor and spontaneous abortion. Consequently inhibition of prostaglandin synthesis has been suggested as a potential means of inhibiting premature labor. There are many controlled studies which have described the use of indomethacin for inhibition of premature labor with success. But...
Influence of Isoproterenol on the Plasma Renin Activity in Rats.
Woong Kyou Park, Yong Bae Shin, In soo Choi, Hyeon Suk Lee, Jung Soo Kim, Kyung Woo Cho
Clin Exp Pediatr. 1985;28(9):899-905.   Published online September 30, 1985
It has been suggested that the effect of catecholamine administered into the renal artery on the plasma renin activity may be controlled by extrarenal beta-receptor. Still the exact mechanism responsible for the increase of the plasma renin activity by catecholamines is obscure. In this experiment I have intended to clarify the involvement of extrarenal beta-receptor concerning renin release in the...
Perinatal Problems in neonates of Elderly Parities.
E H Cho, Y U Kim, K B Kim
Clin Exp Pediatr. 1985;28(9):845-851.   Published online September 30, 1985
Perinatal problems encountered in infants born of elderly mothers were assessed on 347 neonates born of mothers among 8,573 newborns who had been delivered at Kwang-ju Christian Hospital during 3-year-period starting from July, 1981. As the control group served 379 babies born of mothers below 35 years of age, who had been selected raudomly from 8,226 deliveries at the same...
Case Report
A Case of Werdnig Hoffmann Disease.
Woo Yeong Chung, Cheol Lee, Tai Gyu Hwang, In Soon Park, Soon Young Lee, Jong Eun Joo
Clin Exp Pediatr. 1985;28(7):726-730.   Published online July 31, 1985
We experienced a case of Werdnig Hoffmann disease in a 1 year 5 month old female child with the complaint of progressive muscular weakness on both lower extremities. Her development had been almost normal since birth and she could stand alone briefly at 12 months of age, but progressive muscular weakness had been apparent since then. Diagnosis was based on...