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Original Article
Diagnostic effectiveness of fine needle aspiration cytology on pediatric cervical lymphadenopathy
Jun Chul Byun, Byung Kyu Choe, Jin-Bok Hwang, Heung Sik Kim, Sang Sook Lee
Clin Exp Pediatr. 2006;49(2):162-166.   Published online February 15, 2006
Purpose : There are few reports in Korean literature on the diagnostic efficacy of fine needle aspiration cytology(FNAC) for pediatric cervical lymphadenopathy. This study examined the diagnostic value of FNAC on cervical lymphadenopathy in children. Methods : Data from 57 pediatric patients(aged 0.3 to 14 years) who underwent FNAC due to cervical lymphadenopathy between January 2001 and March 2005 was...
Review Article
Helicobacter pylori infection and abdominal pain in children
Jeong Kee Seo
Clin Exp Pediatr. 2006;49(2):136-143.   Published online February 15, 2006
The relationship between H. pylori(Hp) infection and recurrent abdominal pain(RAP) in children is not clear. Current data in the literature regarding a causal relationship between Hp infection and childhood RAP are conflicting. However, meta-analysis and most of the recently published studies have not supported an association between Hp infection and an increased prevalence of abdominal pain. Most published studies have...
New approach to chronic recurrent abdominal pain in children
Hye Ran Yang
Clin Exp Pediatr. 2006;49(2):129-135.   Published online February 15, 2006
Chronic recurrent abdominal pain is a common manifestation in children. Functional abdominal pain is the most common cause of chronic abdominal pain and can be diagnosed properly by the physician without the requirement of specific evaluation when there are no alarm symptoms or signs. Functional abdominal pain is categorized as functional dyspepsia, irritable bowel syndrome, functional abdominal pain, abdominal migraine,...
Early recognition of high risk factors of acute abdominal pain in children
Jin-Bok Hwang
Clin Exp Pediatr. 2006;49(2):117-128.   Published online February 15, 2006
Non-traumatic acute abdominal pain in children presents a diagnostic dilemma. Numerous disorders can cause abdominal pain. Although many etiologies are benign, some require a rapid diagnosis and treatment in order to minimize morbidity. This review concentrates on the clinical office evaluation of acute abdominal pain in infants and children and details the clinical guideline for the diagnostic approach to imaging...
Case Report
Development of Crohn disease in patients with myelodysplastic syndrome : report of two children
Jeong Ok Shim, Jeong Kee Seo, Hye Ran Yang, Jae Sung Ko, Hee Young Shin, Hyo Seop Ahn, Woo Sun Kim, Gyeong Hoon Kang
Clin Exp Pediatr. 2006;49(1):107-111.   Published online January 15, 2006
Crohn disease (CD) is rare, but the incidence of CD has been increasing over the past ten years. We found two cases of CD, associated with myelodysplastic syndrome (MDS), for the first time in children. In the first patient, MDS was diagnosed at three years of age and CD developed later at eight years of age. The patient presented with...
Original Article
Follow-up of children with isolated microscopic hematuria detected in a mass school urine screening test
Mi-sun Yum, Hoe Soo Yoon, Joo Hoon Lee, Hyewon Hahn, Young Seo Park
Clin Exp Pediatr. 2006;49(1):82-86.   Published online January 15, 2006
Purpose : The isolated microscopic hematuria is the most common abnormality detected by school urinary screening, but there is no consensus about the range of investigations and long-term outcomes of isolated hematuria in children yet. This study aims to elucidate the prognosis of hematuria and the range of diagnostic studies by follow-up results. Methods : Students with isolated hematuria who were...
The alteration of the positive rate of cytomegalovirus IgG antibody among preschool period children
Se-Young Seo, Sang-Jun Park, Ja-Young Hwang, Seong-Hoon Hahn, So-Young Kim, Hyun-Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2006;49(1):51-55.   Published online January 15, 2006
Purpose : In order to evaluate the time of disappearance of cytomegalovirus(CMV) IgG antibodies from mothers, and the alteration of the positive rate of CMV IgG antibodies among preschool period children, we investigated the positive rate of CMV antibodies among preschool children. Methods : We studied 391 children who visited the Department of Pediatrics from March, 2001 to February, 2004. We...
Health status of children in low socioeconomic conditions
Hee Kyoung Choi, Jeong A Her, Seong Hee Jang, Dal Hyun Kim, Kyoung Lim Yoon, Young Min Ahn
Clin Exp Pediatr. 2006;49(1):24-28.   Published online January 15, 2006
Purpose : The purpose of this study was to investigate the health status and nutritional condition of children living in a low-income community through anthropometric, laboratory evaluation. Methods : A community-based survey identified children below 15 years living in a low-income community. Their weight, height, visual acuity, hearing level and dental status were measured. Blood sample were obtained on June and...
Trace element concentrations profiles in the hair of normal children living in the northern area of Seoul
Ji Won Kwon, Byung Eui Kim, Mi Jung Park, Sang Woo Kim
Clin Exp Pediatr. 2006;49(1):18-23.   Published online January 15, 2006
Purpose : The reliability of hair mineral analyses regarding nutritional status, environmental exposure or diseases is controversial. The aim of this study was to determine the normal reference range of hair mineral concentration of Korean children. Methods : We examined hair mineral concentrations of 223 children(3-12 yrs old, 110 boys, 113 girls, mean age 8.8?.2 yrs old) living in the...
Usefulness of Korean Infant Developmental Screening Test in Premature Infants
Dong Han Shin, Hee Sun Lee, Jee Yeon Lee, Byung Min Choi, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2005;48(12):1337-1341.   Published online December 15, 2005
Purpose : This study aimed to evaluate the usefulness of Korean Infant Development Screening Test in predicting delayed development in premature infants. Methods : A total of 74 children with histories of prematurity, who visited the pediatric neurology clinic of Korean University Ansan Hospital from August, 2002 to July, 2004, were examined, using the Korean Infant Development Screening Test. They were...
Erratum
Mechanical Ventilation of the Children
June Dong Park
Clin Exp Pediatr. 2005;48(12):1310-1316.   Published online December 15, 2005
Mechanical ventilation in children has some differences compared to in neonates or in adults. The indication of mechanical ventilation can be classified into two groups, hypercapnic respiratory failure and hypoxemic respiratory failure. The strategies of mechanical ventilation should be different in these two groups. In hypercapnic respiratory failure, volume target ventilation with constant flow is favorable and pressure target ventilation...
Original Article
Different Clinical Courses of Henoch-Sch nlein Purpura in Children, Adolescents and Adults
Joo Hee Hong, Hyung Joon Na, Mee Kyung Namgoong, Seung Ok Choi, Byng Geun Han, Soon Hee Jung, Hwang Min Kim
Clin Exp Pediatr. 2005;48(11):1244-1251.   Published online November 15, 2005
Purpose : Henoch-Sch nlein purpura(HSP) is the most common and benign systemic vasculitis in children. Few reports have focused on worse outcomes of HSP in adults. The age of onset is suggested as a main risk factor. We assessed the characteristics of adolescent-onset HSP. Methods : We retrospectively analyzed 205 cases presented from Aug. 1993 to Oct. 2003. Patients were classified...
The Relation between Obesity and Glomerular Filtration Rate in Children and Adolescents
Youngsu Jung, Dongwoon Kim, Inseok Lim
Clin Exp Pediatr. 2005;48(11):1219-1224.   Published online November 15, 2005
Purpose : The prevalence of obesity in children and adolescents has been rising rapidly in Korea because of changes of diet and lifestyle. As with adults, obesity in children and adolescents can cause diabetes mellitus, hyperlipidemia, cardiovascular diseases and renal diseases. The aim of the present study is to examine the relation of obesity, glomerular filtration rate(GFR) and serum cystatin...
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Relationship between △FVC(% fall in FVC at the PC20 Dose of Methacholine) and Serum Eosinophil Cationic Protein(ECP) in 6-8 Year Old Children with Asthma
Dong In Suh, Jinho Yu, Young Yoo, Do Kyun Kim, Hee Kang, Young Yull Koh
Clin Exp Pediatr. 2005;48(10):1126-1131.   Published online October 15, 2005
Purpose : Bronchial hyperresponsiveness(BHR) is considered a hallmark of asthma. Increased levels of eosinophil cationic protein(ECP) have been identified in serum of asthma patients. Several studies have examined the relationship between serum ECP and bronchial responsiveness, expressed as methacholine PC20 in asthmatic patients, with conflicting results. The aims of this study were to examine the relationship between serum ECP and...
Affecting Factors of Insulin Resistance in Obese Children and Adolescents
Duk Hee Kim, Ho Seon Eun, In Kyung Choi, Ho Seung Kim, Bong Soo Cha, Dong Kee Kim
Clin Exp Pediatr. 2005;48(10):1076-1081.   Published online October 15, 2005
Purpose : Insulin resistance is the most important risk factor linked to the development of impaired glucose tolerance(IGT), diabetes mellitus and cardiovascular diseases in childhood and adolescent obesity, The purpose of this study was to see whether insulin resistance of obese adolescent is higher than that of obese children. and to analyze gender difference and affecting factors of insulin resistance. Methods...
The Therapeutic Effect of Lactobacillus reuteri in Acute Diarrhea in Infants and Toddlers
Tae-Hun Eom, Eun-Young Oh, Young-Hoon Kim, Hyun-Seung Lee, Pil Sang Jang, Dong-Un Kim, Jin-Tack Kim, Byung-Churl Lee
Clin Exp Pediatr. 2005;48(9):986-990.   Published online September 15, 2005
Purpose : Certain strains of lactobacilli are known to accelerate recovery from acute diarrhea. Lactobacillus reuteri is isolated from human breast milk and a commonly occurring Lactobacillus species with therapeutic potential in acute diarrhea. The purpose of the present study was to investigate the therapeutic effect of L. reuteri in acute diarrhea in young children. Methods : Fifty patients between...
Clinical Effects of Oseltamivir in Children with Influenza in Busan, in the First Half of 2004
Soo Kyoung Park, So Young Choi, Sung Mi Kim, Gil Heun Kim, Jin Hwa Jung, Im Jung Choi, Kyung Soon Cho
Clin Exp Pediatr. 2005;48(9):976-985.   Published online September 15, 2005
Purpose : Although influenza is one of the most important causes of acute respiratory tract infections in children, effective antiviral therapies are not common and there are only a few clinical studies on treatment of influenza in children. We evaluated the efficacy of oseltamivir in the treatment of naturally aquired influenza in children during the first half of 2004 in...
Clinical Findings of Mycoplasma Pneumonia in Children, from 1998 to 2003
Ji-Hyun Kim, Soo Ahn Chae, Dong-Keun Lee
Clin Exp Pediatr. 2005;48(9):969-975.   Published online September 15, 2005
Department of Pediatrics, College of Medicine, Chung Ang University, Seoul, Korea Purpose : We performed a study of clinical findings of Mycoplasma Pneumonia in children, to know differences between recent clinical manifestations of Mycoplasma pneumonia and previous studies. Methods : The subjects of this study were 393 children who were diagnosed as Mycoplasma pneumonia with high titers of Mycoplasma antibody(≥1 : 160)...
Carotid Intima-Media Thickness Measurement in Obese Children
Kyung Ok Park, Suk Ju Choi, Hee Hyun Yeom, Sochung Chung, Jeong Jin Yu, Youngshin Park, Dong Hwan Lee
Clin Exp Pediatr. 2005;48(9):935-938.   Published online September 15, 2005
Purpose : The aim of the present study was to ascertain whether the increase of carotid intima- media thickeness(cIMT) as one of premature pathologic changes of atherosclerosis, was present in obese children compared to normal weight children. Methods : The obese group consisted of 21 obese/overweight(body mass index(BMI) above 85 percentile of age, sex standards) children and the control group of...
Effects of Growth Hormone Therapy in Children with Idiopathic Short Stature
Kyong A Lee, Heon Seok Han
Clin Exp Pediatr. 2005;48(8):865-870.   Published online August 15, 2005
Purpose : The use of growth hormone(GH) to promote growth in normal short children without classical GH deficiency is controversial. Numerous foreign studies have shown the effects of GH therapy in children with idiopathic short stature(ISS) whereas few has been interested in Korea. Therefore, this study is designed to investigate the effects of GH therapy on ISS by observing correlations...
Hepatitis Complicated with Mycoplasma pneumoniae Infection in Children
Seung Min Lee, Sung Moon Lee, Hann Tchah, In Sang Jeon, Eell Ryoo, Kang Ho Cho, Yong Han Seon, Dong Woo Son, Hee Joo Hong
Clin Exp Pediatr. 2005;48(8):832-838.   Published online August 15, 2005
Purpose : Mycoplasma pneumoniae infection is relatively common in childhood. Its extrapulmonary manifestations have been reported so much, but hepatitis associated with it has been reported rarely in Korea. Methods : A clinical study was performed on 556 patients of M. pneumoniae pneumonia diagnosed serologically at Gil hospital from January 2001 to December 2004. We reviewed 65 cases among these patients,...
Case Report
A Case of Cat Scratch Disease Confirmed by Polymerase Chain Reaction for Bartonella henselae DNA
Ju-Young Chung, Ja Wook Koo, Sang Woo Kim, Young Sam Yoo, Tae Hee Han, Seong Jig Lim
Clin Exp Pediatr. 2005;48(7):789-792.   Published online July 15, 2005
We report a case of cat scratch disease (CSD) caused by Bartonella henselae in a 14-year-old boy who developed lymphadenopathy in the right cervical area, after a raising canine pet for 10 months. The cervical lymphadenopathy persisted for 14 days. Immunofluorescent antibody testing for B. henselae with the patient's serum was 1:64 positive. Polymerase chain reaction (PCR) analysis using the...
Original Article
DNA Methylation Change of IL-4 Gene from T Cell in Allergic Children
Jae Won Oh, Myung Gul Yum, Chang Ryul Kim, In-Joon Seol, Su A Shin, Ha Baik Lee, Se Jin Jang
Clin Exp Pediatr. 2005;48(6):634-639.   Published online June 15, 2005
Purpose : An understanding of the immunological process is required if primary prevention of atopic diseases is to be developed in early childhood. But, it is too hard to distinguish atopy from nonatopy under the age of two clinically, because the expression of phenotype and cytokines is vague in early childhood. We evaluated DNA methylation changes at Th2 interleukin-4 gene...
The Value of Serum Concentration of Cystatin C as a Marker for Glomerular Filtration Rate in Children and Adolescents
Young-Su Jung, In-Seok Lim
Clin Exp Pediatr. 2005;48(6):614-618.   Published online June 15, 2005
Purpose : Cystatin C has been proposed for the assessment of glomerular filtration rate, being more accurate than creatinine determination. We measured serum cystatin C concentrations in the pediatric population, and analysed the correlation between cystatin C and glomerular filtration rate. Methods : Cystatin C and creatinine were measured by the particle enhanced nephelometric immunoassay and Jaff method, respectively, in...
A Clinical Study of Acute Poststreptococcal Glomerulonephritis in Children, from 1994 to 2003
So Eun Koo, Hyewon Hahn, Young Seo Park
Clin Exp Pediatr. 2005;48(6):606-613.   Published online June 15, 2005
Purpose : Acute poststreptococcal glomerulonephritis(APSGN) is a common form of glomerulonephritis in children. Most patients recover completely after the acute phase but a few patients have acute complications or progress to chronic renal disease. In recent years, the frequency of APSGN has been was decreasing but is still common in children. So we studied the clinical characteristics of APSGN from...
Bone Mineral Density and Bone Markers in the Children with Epilepsy Taking on Chronic Anticonvulsants
Soon Bum Lee, So Young Kang, Jeesuk Yu
Clin Exp Pediatr. 2005;48(5):527-533.   Published online May 15, 2005
Purpose : Long-term administration of anticonvulsants in children with epilepsy may cause short stature, hypocalcemia and low bone mineral density. This study was performed for the early detection of abnormal bone metabolism in children with epilepsy on taking anticonvulsants. Methods : Thirty children aged 5 to 16 years who were diagnosed with epilepsy were enrolled in this study. All had taken...
Airway Expandible Metallic Stent Implantation in Children with Tracheal or Bronchial Stenosis
Ju Young Jang, Hyo-Bin Kim, So Yeon Lee, Ja Hyung Kim, Seong Jong Park, Ji Hoon Shin, Soo-Jong Hong
Clin Exp Pediatr. 2005;48(5):512-517.   Published online May 15, 2005
Purpose : In adults, endoscopic tracheobronchial balloon dilatation and stenting have become valuable methods to establish and maintain an adequate airway lumen when tracheomalacia or neoplastic growth compromise the airways. But in children, only a few cases were reported due to technical problems. We report six children who were treated with stent implantation and describe the use and safety of...
Serum Adiponectin Levels and Insulin Resistance in Obese Children
Hee-Sun Lee, Jin Lee, Min-Joo Kang, Byung-Min Choi, Kee-Hyoung Lee
Clin Exp Pediatr. 2005;48(5):481-487.   Published online May 15, 2005
Purpose : Adiponectin, adipose tissue-specific protein, has anti-inflammatory and anti-atherogenic properties. It has been found to have a negative correlation with obesity and to play a role in modulating glucose tolerance and insulin sensitivity. Serum adiponectin concentrations are decreased in adults with obesity and type 2 diabetes. We investigated the difference in adiponectin levels between obese and non-obese children, and...
Clinical Lecture
The Effects of Postpartum Depression on the Development of Children
Esook Oh
Clin Exp Pediatr. 2005;48(5):469-475.   Published online May 15, 2005
Mother-infant interaction is a crucial component of an infant's cognitive, emotional and behavioral development. Most people are preoccupied with fetal education, the physical conditions of the postpartum mother and baby, and emphasizing an early start in the child's education. However, the effects of a mother's postnatal emotional state on the development of the infant are often overlooked. Postpartum depression is...
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