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Original Article
Characteristics of Seizures and Neuronal Nitric Oxide Synthase Expression of Hippocampus in Hyperthermia-Induced Seizures of Developing Rat
Doo-Kwun Kim, Dong-Keun Jung
Clin Exp Pediatr. 2002;45(5):629-636.   Published online May 15, 2002
Purpose : Our study was aimed to investigate the characteristics of seizures as well as to determine whether the expression of neuronal nitric oxide synthase expression(nNOS) of hippocampus has an affect in the hyperthermic seizure in developing rat. Methods : Hyperthermic seizures were repeatedly induced twice a week for four weeks in 20-day old Spraque-Dowley rats. Fifty two rats were used...
Effects of Vigabatrin on Pilocarpine-Induced Seizures in Immature Rats
Bo Ram Choe, In-Goo Lee, Kyung-Tae Whang
Clin Exp Pediatr. 2001;44(2):185-192.   Published online February 15, 2001
Purpose : Vigabatrin is a widely used antiepileptic drug that greatly increases whole brain γ- aminobutyric acid(GABA). But little is known about the anticonvulsant effect of vigabatrin on pilocarpine-induced seizures in the immature rats. This study was conducted to determine the effects of vigabatrin on pilocarpine-induced seizures in the immature rats. Methods : Six to eight day old Sprague-Dawley rats were...
A clinical study on neonatal seizures.
Bong Sik Kong, Ri Sa Lee, Sang Kyu Park, Ho Jin Park
Clin Exp Pediatr. 1991;34(2):230-239.   Published online February 28, 1991
Clinical observation were made on 57 cases of neonatal seizure who were admitted to the Depart- ment of pediatrics, Seoul Red Cross Hospital during the period of 7 years from Jan. 1983 to Dec. 1989. The results were as follows: 1) According to the type of delivery of neonates which showed neonatal seizure, normal vaginal delivery were 41 cases (71.9%), C-section delivary 11 cases (19.3%)...
Blood Level of Phenobarbital in Treatment of Seizure After Neonatal Asphyxia.
Ji Yean Lee, Heng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1989;32(9):1265-1272.   Published online September 30, 1989
In this study, we attempted to determine an optimal first dose of phenobarbital for the treatment of seizures in the asphyxiated full term neonates. Blood samples were obtained 2 to 48 hours after the administration of final effective loading dose and plasma levels were determined by the EMIT system. Four groups of neonates were studied. Six neonates (Group 1) received an intravenous loading dose of...
A Clinical Study on Neonatal seizures.
Chong Young Park, Myung Kul Yun, Jung Hwan Choi, Yong Seung Hwang, Chong Ku Yun
Clin Exp Pediatr. 1985;28(3):225-235.   Published online March 31, 1985
Clinical Observations were made on 96 cases of neonatal seizure who were admitted to the Department of Pediatrics, Seoul National University Hospital during the period of 5 years from June, 1979 to May, 1984. The results were as follows: 1)The most frequent cause of neonatal seizure was sepsis with or without meningitis (27.4%), and followed by hypocalcemia(23.4%)> hypoxic-ischemic brain damage(12.9%), hypoglycemia(8.0%), intracranial...
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