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Original Article
Clinical effects of yeast derived recombinant methionyl growth hormone in growth hormone deficiency.
Byung Churl Lee
Clin Exp Pediatr. 1991;34(3):334-339.   Published online March 31, 1991
Since the success of human growth hormone (hGH) synthesis by recombinant DNA technology, these GH products are used in the treatment of growth hormone deficiency. Recently, methionyl-GH has been produced in the yeast, Saccharomyces cerevisiae 2150 by the use of a recombinant method. In this paper, the clinical efficacy and. immunogenicity of this GH was studied during therapy of 1 year in 20 children...
Clinical Obervation in 40 Cases with Neonatal Sepsis.
Jung Hee Lee, Jae Jin Park, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1990;33(11):1489-1494.   Published online November 30, 1990
Sepsis is still one of major causes of mortality and morbidity in neonatal period and early diagnosis and appropriate treatment for neonatal sepsis is difficult due to its vague clinical manifestation and rapid progress. An analysis of 40 cases of neonatal sepsis confirmed by clinical manifestation and blood cultures from Jan. 1986 to Dec. 1989 at nursery of St. Mary’s Hospital of Catholic University...
Mechanical Ventilation in Newborn Infants.
Young Back Hahm, Jong Ho Sung, In Kyung Sung, Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):10-21.   Published online January 31, 1990
Clinical analysis of 5 years* experience with mechanical ventilation of 68 neonates in NICU of St. Mary’s Hospital, from Jan. 1983 to June 1988, was done. The results were as follows; 1) Indications for mechanical ventilation were hyaline membrane disease(51.5%), postasphyxia syndrome(19.1%), apnea of prematurity (5.9%), sepsis (5.9%), intracranial hemorrhage (5.9%) and others. 2) Number of male patients was 33(48.5%》and of female was 35(51.5%), and male to female...
A Case of True Hermaphroditism.
Hi Young Chun, Won Suk Suh, Byung Churl Lee
Clin Exp Pediatr. 1989;32(8):1174-1179.   Published online August 31, 1989
A hermaphrodite in an individual in whom both testicular and ovarian tissues are present. A 15-year old boy presented with breast development and hypospadias. On physical examination, his height, weight, and arm span were normal. He had stage 4 breast development and normal pubic (stage 4) and axillary hair. He also had hypospadias in spite of corrective surgery 2 times. And his karyotype was...
A Case of the Hepatoblastoma with Precocious Puberty.
In Young Park, Byung Jun Lee, Byung Churl Lee
Clin Exp Pediatr. 1989;32(5):735-740.   Published online May 31, 1989
Hepatoblastoma is a rare neoplasm in childhood. Hepatoblastoma associated with precocious puberty caused by human chorionic agonadotropin (HCG) secreted by the tumor itself, is very rare. We experiened a case of hepatoblastoma with precocious puberty in a 28-month-old boy, who was admitted because of abdominal pain, enlarged testis & penis, pubic hair and a deep voice. Diagnosis was made by typical Clinical manifestation, elevated...
Two Siblings of Congenital Hypothyroidsm due to Organification Defect.
Young Kie Park, Kwang Sun Park, Byung Churl Lee
Clin Exp Pediatr. 1989;32(4):582-588.   Published online April 30, 1989
Congenital hypothyroidism due to a variety of defects in the biosynthesis of thyroid hormone is detected in 1/30,000-50,000 live births. In the iodide organification defect which is one of defect in the biosynthesis of thyroid hormone, iodide is not organified and may be rapidly discharged from the thyroid by administration of perchlorate. We experienced two siblings who had short stature, goiter, mental retardation, constipation and other...
A Case of Chondrodysplasia Punctata of the Rhizomelic Type.
Ki Sik Min, Bo Kyung Cho, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1989;32(1):87-91.   Published online January 31, 1989
Chondrodysplasia punctata is a rare familial disorder of bone, characterized by punctate calcifica- tion in the epiphyseal regions. We experienced a case of the rhizomelic type of chondrodysplasia punctata in an one day old female. She had symmetrical shortening of the proximal limbs, flexion contracture of both hip joints, cataracts and ichthyotic skin lesion. Radiologic findings showed multiple stippled calcified densities in most joints and...
A Case of Primary Hyperparathyroidism in Childhood.
Dong Sung Kim, Soon Joo Lee, Kyung Il Lee, Byung Churl Lee
Clin Exp Pediatr. 1988;31(10):1350-1357.   Published online October 31, 1988
Primary hyerparathyrodism is rare in children under the age of sixteen and is characterized by conspicuous skeletal and renal changes. An 11 years old male patient who had complained of severe lower back pain, nausea and vomiting since last 3 months, showed typical laboratory and radiological findings of primary hyperparathy roidism. Confirmatory diagnosis was made by elevated serum parathyroid hormone concentration, imaging method by technetium-thallium subtraction...
One Case of Pheochromocytoma.
Jong Jin Kim, Jung Oh Kim, Sung Won Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(7):942-947.   Published online July 31, 1988
The Pheochromocytoma is a rare tumor of childhood and can arise from chromaffin tissue anywhere in the body. Most commonly it is located in the adrenal medulla, especially on the right side. We experienced a case of pheochromocytoma in a 14 year old boy, who had paroxysmal palpitation, perspiration, dyspnea and contemporary paroxysmal hypertension. Diagnosis was made by clinical features, elevated plasma catecholamine concentration,...
A Case of Acute Hepatic Porphyria.
Young Cheal Han, Sin Hang Joo, Jin Han Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(2):253-257.   Published online February 28, 1988
Acute hepatic porphyria may be an inborn error of metabolism characterized biochemically by the excessive hapatic over-production and urinary excretion of porphyrin precursors and clinically by episode of acute neuro-visceral dysfunction. Acute porphyria is very rare in childhood. We experienced a case of acute hepatic porphyria in childhood age, confirmed by characterized clinical features of neuro-visceral dysfunction and biochemical findings in blood and urine...
Clinical Analysis of Congenital Malformations in the Newborn Infant.
Hoon Chang, Chae Hwa Lee, In Kyung Sung, Byung Churl Lee, Sung Hoon Cho
Clin Exp Pediatr. 1988;31(1):72-77.   Published online January 31, 1988
Congenital malformations are still one of the leading problems of neonatal death and illness. But, we have only a few data for about it, because of difficulty in the exact analysis of the incidence and etiologic factors. During the period of 6 years, between January 1980 and December 1985, a clinical study about the general incidence of congenital malformations was done on 50, 979...
Clinical Study of Congenital Hypothyroidism.
Byung Churl Lee, Soon Joo Lee, Sung Hoon Cho
Clin Exp Pediatr. 1987;30(12):1401-1408.   Published online December 31, 1987
We reviewed 24 patients with congenital hypothyroidism to observe the etiology, clinical symptoms and signs, bone age, height age, the degree of mental retardation and growth velocity after treatment form Jan. 1983 to June 1987. The results were as follows: 1) The male to female ratio was about 1:3.8. The cases diagnosed under 1 year old were only 12.5%. 2) In etiologic classification, thyroid dysgenesis...
Statistical Observations for Pediatric Inpatients.
Byung Cheol Han, Hack Ki Kim, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1987;30(4):385-392.   Published online April 30, 1987
We observed the patients admitted to the department of pediatrics of St. Mary*s Hospital, Catholic Medical College during the past 20 years from Jan. 1966 to Dec. 1985 and classified them by year and disease according to the International Classification of Disease by W.H.O. (1965 Revision). The results were as follows: 1) The total number of pediatric inpatients during 20 years was 18,686, of which...
Case Report
A Case of Poland Syndrome.
Jong Deok Kim, Hyung Kook Ki, In Kyung Sung, Byung Churl Lee
Clin Exp Pediatr. 1987;30(1):99-101.   Published online January 31, 1987
The Poland syndrome consists of congenital unilateral absence of the pectoralis major muscle and ipsilateral anomalies of the hand, typically syndactyly. It may be combined with many other anomalies. Recently, we experienced an 8 days old boy, who had the total absence of the metacarpals and phalanges of left hand and defect of the pectoralis muscle on the same side. A brief review of the...
A Case of Chondroma in the Mediastinum.
Hyun Mee Lee, Jin Oh Lee, Hack Ki Kim, Byung Churl Lee
Clin Exp Pediatr. 1986;29(10):1143-1146.   Published online October 31, 1986
Most chondroma often occur within or on the surface of the tubular bone and soft tissue, and are also found in many organs, but it is extremely rare in the mediastinum. Recently, we experienced a case of chondroma of the middle mediastinum, in a 13-years old girl with intermittent chest discomfort and exertional dyspnea for several months. Diagnosis was made by...
Three Cases of Renal Tuberculosis in children.
Young Hwa Joung, Kyoung Soo Kim, Sung Won Kang, Kyu Hong Cho, Byung Churl Lee
Clin Exp Pediatr. 1985;28(9):916-921.   Published online September 30, 1985
Kidney tuberculosis is serious complication during childhood just as later life because the disease tends to invade and to destroy both kidney. We reported three cases of renal tuberculosis in 8-yr-old female, 10-yr-old female and 6- yr-old male child. Case 1 and 3 had complaints of continuous fever and poor appetite and case 2 had complaints of dysuria and urinary...
A Case of Acute Lymphocytic Leukemia Successfully Treated with Allogeneic Bone Marrow Transplantaion.
In Kyung Sung, Byung Churl Lee, Kyong Su Lee, Du Bong Lee, Chong Won Park, Chun Choo Kim, Dong Jip Kim
Clin Exp Pediatr. 1985;28(8):805-811.   Published online August 31, 1985
A 8-year old boy with acute lymphocytic leukemia who had shown resistance to repeated combination chemotherapies, was successfully grafted with bone marrow from his HLA- matched sister. He was in the third partial remission at the time of bone marrow transplantation. He was conditioned with cyclophosphamide 60 mg/kg/day on two consecutive days, followed by 800 rads total body irradiation. Marrow...
Original Article
Neonatal Mortality Rate.
Byung Kyu Suh, Dong Ku Lee, Byung Churl Lee
Clin Exp Pediatr. 1984;27(5):425-432.   Published online May 31, 1984
A statiscal study on 18,679 newborns who were born in pediatric department of ST. MARY’S Hospital, ST. PAUUS Hospital, Kang-Nam ST. MARY*S Hospital and OUR LADY OF MERCY Hospital in Catholic Medical College from January, 1980 to December, 1982 was performed. Authors studied the mortality rate by birth weight, gestational period, sex, time after birth, Apgar score, mode of delivery...
Epidemiologic and Clinical Study of Mucocutaneous Lymphnode Syndrome in Korea.
Du Bong Lee, Kyong Su Lee, Byung Churl Lee, Ik Jun Lee
Clin Exp Pediatr. 1982;25(10):977-993.   Published online October 31, 1982
Mucocutaneous Lymphnode Syndrome (MCLS) becomes familiar to pediatrician recently as a new disease entity. However, the pathogenesis of this syndrome is not know yet. Since Dr. Kawasaki’s first cases had reported in 1963, over 30,000 cases of this disease has "been reported in Japan. This study was undertaken to know the epidemiologic status of this dis- ease in this country. The materials were collected from...
Epidemiological Study on Diseases of Korean Children in Urban & Rural Areas.
Du Bong Lee, Sung Hoon Cho, Kyong Su Lee, Byung Churl Lee
Clin Exp Pediatr. 1980;23(3):173-197.   Published online March 15, 1980
This study was attempted to know the recent changes of the patterns of diseases among Korean children living inurban and rural areas. 21,498 sick-children, who admitted to the thirteen general hospitals which located in urban and rural areas during past five years from Jan. 1994 to Dec. 1978, were analysed for this purpose. 13,759 sick-children(64.0%) were male, others were female...
Feeding Results of Maeil Dry Milk G-80 in Low Birth Weight Infants.
Yong Eun Jung, Hyo Sup Kim, Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1979;22(11):956-960.   Published online November 15, 1979
The low birth weight infants have been fed with 15% concentration of Maeil Dry Milk G-80(Table 1) until the date of weight gaining to 2.5kg at the nursery room of our pediatric department, St. Mary's Hospital, Catholic Medical College. Feeding results were obtained as follows. 1. General physical condition was fair. The initial weight loss was average 6.8% of their...
Clinical Observation of Type A Hepatitis in Children.
Byung Churl Lee, Du Bong Lee
Clin Exp Pediatr. 1979;22(3):213-222.   Published online March 15, 1979
We observed 241 cases of type A hepatitis who were admitted to pediatric department of St. Mary`s Hospital, Cathlic Medial College from Jan. 1,1968 to Dec. 31,1977, and the following results were obtained. 1. Annual incidence was the highest in 1975 and lowest in 1969, but wr observedno significant difference. 2. Seasonal incidence was high in Autumn and Winter, and...
Clinical Evaluation of Children with Psychiatric Problems among Pediatric Patients.
Kyung Tai Whang, Byung Churl Lee, Sung Hoon Cho, Haeng Sook Kim
Clin Exp Pediatr. 1978;21(3):198-206.   Published online March 31, 1978
Patients who visited to the pediatric department sometimes present psychiatric problems, but this interesting field seems to have been neglected frequently by clinicians. The authors were analyzed 130 cases of pediatric patients who referred to psychiatric department for the evaluation of psychiatric problems from July, 1974 to June, 1977 at the St. Mary's hospital, Catholic medical college. The results were...
Case Report
A Case of Juvenile Rheumatoid Arthritis
Tae Kyoo Park, Byung Churl Lee, Jae Chung Lee, Sang Duck Cha
Clin Exp Pediatr. 1973;16(5):397-401.   Published online May 31, 1973
We have experienced a case of juvenile rheumatoid arthritis in 5 year and 4 months old female. She had multiple subcutaneous nodules and arthralgia with fever on admission. The diagnosis was established by clinical, laboratory and X-ray findings. The pertinent literature are reviewed briefly.
Case Report
A Case Report of Cleidocranial Dysostosis
Byung Churl Lee, Tae Kyoo Park, Chung Kyu Kim, Kee Tae Kim
Clin Exp Pediatr. 1973;16(4):341-344.   Published online April 30, 1973
We experienced a new form of cleidocranial dysostosis. Patient is characterized by absence of the both clavicles, defective and limitted ossification of calvarium, limitted ossification of both pubic and ischiac bone. A brief review of literature was made.
Case Report
Two Cases of Idiopathic Dilatation of the Common Bile Duct
Jung II Kim, Byung Churl Lee, Young Joon Kim, Sang Duk Cha
Clin Exp Pediatr. 1972;15(11):1053-1057.   Published online November 30, 1972
Authors had experienced 2 cases of idiopathic dilatation of the common bile duct which was diagnosed by clinical, laboratory, X-ray and surgical findings. CaseⅠ in 4 years old girl has been observed for 1 ½ years after choledochoduodenostomy and caseⅡ in 10 years old boy has been followed up for 6 months after choledochojejunostomy (Roux-en-Y) without any complications. The review of the literature was...