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Original Article
Re-evaluation of TSH Screening TEST in Neonates
Jin Young Song, Dong Woo Son, Beyong Il Kim, Sei Won Yang, Jung-Hwan Choi, Chong Ku Yoon, Hyung Ro Moon
Clin Exp Pediatr. 1993;36(11):1502-1506.   Published online November 15, 1993
Five years ago, we made the cut-off value of TSH by dry filter paper method as 15μU/ml to screening congenital hypothyrodism. Since then, 1,210 term neonates, who had no perinatal problems, screening test with this cut-off point. Neonates had been recalled for measurement of serum T4/TSH to rule out congenital hypothyroidism if their TSH value by screening tests reveal more...
The Variability of Growth Hormone(GH) Response to Growth Hormone-Releasing Hormone(GHRH) according to the intrinsic Growth Hormone Secretory Rhythm in Children with Normal Growth Hormone Reserve
Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1993;36(3):312-319.   Published online March 15, 1993
The diagnostic value of GHRH in assenssing GH secretion in biochemical GH suficient short children was examined. GHRH(1㎍/kg i.v bolus) was given to three groups (upslope, trough, downslope) arbitrarily classified according to the basal pulsatile GH secretory pattern before GHRH administration. Cmax following GHRH administration were variable and overlapping. Two children in downslope group, three children in though group, and one...
Medical Lecture Course
Pulsatile Growth Hormone Secretion
Sei Won Yang
Clin Exp Pediatr. 1992;35(5):587-594.   Published online May 15, 1992
Original Article
The etiologies and the clinical manifestations of hypoglycemia in infancy and childhood.
Nam Seon Beck, Dong Joo Shin, Heon Seok Han, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1991;34(4):480-486.   Published online April 30, 1991
To analysis age at onset, clinical manifestations, etiologies, complication and management of hypoglycemia, the authors reviewed seventeen cases of hypoglycemia who were admitted to Seoul National University Children’s Hospital because of hypoglycemic symtoms from March, 1982 to February, 1990. In neonate group, which included five patients, their initial symtoms were apnea, cyanosis, sweating and hand rigidity, with the causes of two hyperinsulinemic hypoglycemias, one...
Pituitary Function on Patients with Sellar and Suprasellar Tumor.
Sei Won Yang, Hyung Ro Moon, Byung Kyu Cho
Clin Exp Pediatr. 1990;33(4):491-498.   Published online April 30, 1990
We observed the status of pituitary hormones (growth hormone, TSH, ACTH, gonadotropin and ADH) in the patients with intrasellar and suprasellar tumors (Table 1 and 2) before and after treatment of tumors. They were estimated from the results of various provocative tests to the pituitary hormones after confimation of normal thyroid function. The results were as belows (Table 3 and 4): 1) Most patients with craniopharyngioma...
A Case of Mixed Gonadal Dysgenesis.
Byung Ran Yun, Jae Il Sohn, Sei Won Yang, Hyung Ro Moon, Je Geun Chi
Clin Exp Pediatr. 1989;32(12):1757-1762.   Published online December 31, 1989
Mixed gonadal dysenesis is a disorder of sexual differentiation which is characterized by streak gonad associated with contralateral tesis, persistent Mullerian duct structures and/or sex chromosomal mosaicism most commonly with 45, X/46, XY. The authors experienced a case of mixed gonadal dysgensis in a 6-year old child who was reared as female and admitted due to clitoral enlargement. The patient had asymmetrical gonads consisted with...
Bone Age Determination and Hand Radiographic Findings in Children With Russell-Silver Syndrome.
Hun Kyu Lim, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1989;32(6):823-833.   Published online June 30, 1989
Russell.Silver syndrome is a disease of unknown etiology characterized by prenatal onset dwarfism irrespective of full term gestation, growth retardation, body asymmetry, craniofacial dysproportion with a triangular face, short and incurved little finger, etc. Forty.two children were diagnosed as Russell.Silver syndrome by Silver’s criteria at SNU Children' s Hospital from Apr. 1981 till Aug. 1988, and we reviewed clinical data and hand radiographs of...
Study on the Clitoral Size of the Korean Female Newborn.
Jong Lin Rhi, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1988;31(8):1007-1013.   Published online August 31, 1988
The disturbance of sex hormone secretions during the fetal life results in abnormal development of the fetal sex organs including the external genitalia. In the congenital adrenal hyperplasia, especially, the external genitalia is often virilized at birth and the clitomegaly in this disorder can be an important clue for the early diagnosis. For the normal range of the clitoral size of the Korean female...
Comparison of the Effects of Portacaval Shunt and Dietary therapy in Type I Gyocogen Storagy Diseases(GSD).
Dong Hyun Ju, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1988;31(6):762-771.   Published online June 30, 1988
Type I GSD is a metabolic disease resulted from defective glucose-6-phosphatase activities in liver, kindey and intestine. They are characterized by growth retardation, enlargement of liver and kidney, hypoglycemia, hyperuricemia, and hyperlipidemia. Various methods were suggested for the management of GSD. They are night-time nasogastric feeding of glucose solution with frequent day-time feeding, intravenous hyperalimentation, cornstarch therapy end-to-side portacaval shunt, etc. In this study, the effects...
Normal TSH Levels in Neonates by TSH Screening test.
Jae Won Song, Jong Lin Rhi, Sei Won Yang, Jung Hwan Choi, Chong Ku Yun, Hyung Ro Moon, Bo Youn Cho, Chang Soon Koh
Clin Exp Pediatr. 1988;31(6):754-761.   Published online June 30, 1988
In 110 term neonates without perinatal problems who were bom in SNUH, blood TSH levels were measured by TSH screening test for congenital hypothyroidism. The results are as follows 1) Normal TSH level was 14.8±7.8 µU/ml, 8.8±4.7 µU/ml, and 6.5±2.7 µU/ml in neonates of age 0 〜24 hours, 24—48 hours, and 48〜72 hours respectively, and all TSH values in neonates of age 48〜72 hours were...
A Case of Familial Dysautonomia.
Hong Jin Lee, Dong Kyu Jin, Sei Won Yang, Jeong Kee Seo, Hyung Ro Moon, Je Geun Chi
Clin Exp Pediatr. 1988;31(5):648-654.   Published online May 31, 1988
Few documented cases of Familial dysautonomia fulfilling current diagnostic criteria have been recognized in non-Jews especially in orientals. In our case diagnosis was established in 8 year old Korean girl. She fulfilled 8 out of 9 essential diagnostic criteria of Riley. It represents a report of this syndrome with achalasia and improved with modified Heller’s myotomy.
The Prevalence of Antithyroid Autoantibodies in Korean Children.
Bung Hai Ahn, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1988;31(3):329-338.   Published online March 31, 1988
The prevalence of antithyroid autoantibodies and the relationship between the presence of autoantibodies and thyroid functions were studied in 752 Korean children of 10 to 15 years of age with normal thyroids. Antimicrosomal antibodies (AMA) were measured by the indirect agglutination technique using artificial gelatin particle carriers sensitized with thyroid microsomal antigen and antithyroglobulin antibodies (ATA) by the tanned red cell hemagglutination technique. Circulating AMA...
Russell-Silver Syndrome.
Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1986;29(7):715-722.   Published online July 31, 1986
Seventeen cases(12 boys and 4 girls) with Russell-Silver syndrome were evaluated for weight, height and bone age at initial presentation and during follow up. 1) Distribution of patient` s age at initial presentation was between 1 day and 75/12 year of age. 2) In 14 cases, the birth weight was below 3 percentile except for one case(3 percentile). In 15 cases, the...
Congenital adrenal Hyperplasia.
Byoung Hai Ahn, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1986;29(6):604-612.   Published online June 30, 1986
Clinical data of twenty-eight children with congenital adrenal hyperplasia who were admitted to the Seoul National University Hospital from June 1979 to July 1984 were analyzed retrospectively. Male to female ratio was 1 : 1.3. The average age at diagnosis was 3.2 years, 1.3 months for eleven salt-losers and all were 3 months or younger, 4.6 years for seventeen nonsaltlosers....