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Original Article
A case of acute megakaryoblastic leukemia with Down syndrome.
Sung Jin Chang, Sung Min Sohn, Heung Sik Kim, Chin Moo Kang, Dong Seok Jeon
Clin Exp Pediatr. 1991;34(12):1730-1735.   Published online December 31, 1991
We experienced a case of acute megakaryoblastic leukemia (M7) with Down syndrome. The patient was admitted due to premature SGA, which revealed characteristic facial figure of Down syndrome. M7 was diagnosed with PB smear which showed abundant megakaryoblast and confirmed by using the monoclonal antiplatelet glycoprotein IIb/IIIa antibody (J 15). On 25th hospital day, the patient gained weight but discharged without further treatment of M7. Authors...
The diagnosis of mycoplasma pneumoniae pneumonia by high density composite particles agglutinin test.
Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Kyu Chul Choeh
Clin Exp Pediatr. 1991;34(8):1102-1109.   Published online August 31, 1991
In a prospective investigation of 21 chi Idem 3 years of age or more with Mycoplasma pneumoniae pneumonia, we analyzed the diagnostic efficacy of High Density Composite Particles Agglutinin(HDDA) test comparing with cold agglutinin tests and clinical findings. The results obtained were as followed. 1) Among 24 total cases, the number of cases showing positive reaction to HDPA and to cold agglutination test were 17 and...
The relationship between diuresis and pulmonary function in respira- tory distress syndrome of the newborn.
Eun Ae Park, Yung Sook Ko, Gyoung Hee Kim
Clin Exp Pediatr. 1991;34(8):1086-1092.   Published online August 31, 1991
The purpose of this study was to determine the relationship between improvement of pulmonary, function and diuresis in respiratory distress syndrome. This study was based on 24 cases of RDS infants admitted in NICU of Ewha Womans University from January 1988 to December 1990. The results were as follows. 1) Mean birth weight of study cases was 2.11 kg with gestational age between 29〜39 weeks. 2) Maximum...
Bone mineral density of normal Korean children.
Kyu Young Lee, Byoung Yul Lim, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Seol Kim
Clin Exp Pediatr. 1991;34(5):605-613.   Published online May 31, 1991
The diagnosis of renal osteodystrophy and osteoporosis is established by clinical manifestations, biochemical laboratory tests, X-ray and bone scan but early diagnosis, determination of treatment of various metabolic bone diseases are not satisfied with any above methods. Dual energy X-ray absorptiometry (DEXA) has been shown to be a reliable, reproducible, and noninvasive way to assess bone mineral status. We evaluated the bone mineral density...
Transient symptomatic zinc deficiency in a breast-fed, post term infant.
Jin Bok Hwang, Soon Young Song, Woo Hyun Kwon, Chang Ho Han, Hye Li Chung, Young Dae Kwon
Clin Exp Pediatr. 1991;34(1):101-106.   Published online January 31, 1991
Acrdermititis enteropathica is a rare autosomal recessive disorder of zinc absorption and its cardinal symptoms appear at the time of weaning from breast milk which has been referred to as most appropriate formula to prevent and treat this disease. However, recent reports presented Transient Symptomatic Zinc deficiency (TSZD) in infants fed breast milk whom they treated with transitory zinc supplement with no recurrence. We experienced...
HLA Typing, Islet Cell Antibody and C-Peptide of Insulin Dependent Diabetes Mellitus in Children.
Hyeong Rae Cho, Sei Joong Ko, Duk Hi Kim, Hyun Chul Lee, Kap Bum Huh
Clin Exp Pediatr. 1990;33(12):1705-1712.   Published online December 31, 1990
35 childhood insulin-dependent (Typel) diabetes mellitus were typed for HLA and examined for presence of islet cell antibody and level of C-peptide. The following results were obtained: 1) HLA types were present as follows; HLA A24 (9) in 58%, DR3 in 38% and DR4 in 62%. This was slightly higher than the Korean population of 38%, 7% and 48% but there was no significant difference. 2) When...
Change of Auditory Brainstem Response(ABR) on Neonatal Asphyxia.
Jeong Sam Jeon, Chong Woo Bae, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1391-1396.   Published online October 31, 1989
Neonatal asphyxia is insult to the newborn due to lack of oxygen or perfusion to various organs. It is associated with tissue hypoxia, especially brain. So hypoxic-ischemic brain injury is the most important complication known as hypoxic-ischemic encephalopathy. The EEG as well as various evoked potentials (auditory, visual and somatosensory) may assist in evaluating the severity of the damage. This study was undertaken to...
A Case of Mixed Gonadal Dysgenesis.
Eun Young Choi, Min Sik Kim, Hey Sun Lee, Young Min Ahn, Kyung Joon Min
Clin Exp Pediatr. 1989;32(7):1023-1029.   Published online July 31, 1989
The syndrome of Mixed Gonadal Dysgenesis is characterized by a unilateral testis, usually intra- abdominal a streak gonad on contralateral side, persistent Mullerian structures and ambiguous genitalia. These patients are chromatin negative and exhibit XO/XY mosaicism, probably resulting from a cytogenetic error very early in embryogenesis. The testis and the streak gonad should be removed because of the potential devlopement of a gonadoblastoma and the virilization...
A Case of Adrenoleukodystrophy.
Kee Sung Yang, Soo Tack Bae, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1989;32(3):430-437.   Published online March 31, 1989
We experienced a case of Adrenoleukodystrophy (ALD), which is a genetically determined metabolic disorder associated with progressive demyelination of brain white matter and adrenal insuficiency. An 11 year old male revealed rapidly evolving neuologic progression, decreased adrenal reserve, increased plasma content of very long chain fatty acids (VLCFAs) and typical radiological findings. We report here the clinical findings of this patient with brief review of...
Continuous Arteriovenous Hemofiltration in Children.
Hae Il Cheong, Dong Kyu Jin, Young Seo park, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1989;32(2):230-238.   Published online February 28, 1989
Among those who were admitted to the Pediatric Intensive Care Unit (PICU), Seoul National University Children’s Hospital and developed acute renal failure (ARF) during the disease course, 11 children received continuous arteriovenous hemofiltration (CAVH) by pediatricians during a 3-year- period from Nov. 85 to Oct. 88. Their clinical findings were analyzed retrospectively, and the results were as follows; 1) They were 5 boys and 6...
Comparative Study of the Abilities of Visual Motor Integration in Korea Children to That of Berry's Results.
Chang Jun Coe, Young Hyuk Lee
Clin Exp Pediatr. 1989;32(2):191-197.   Published online February 28, 1989
Visual.Motor Integration (VMI) test, designed by Beery, is one of the battery, which is commomly used in investigating the developmental status of child. As the test was designed for American children, the test may be not feasible for Korean children because of difference of cultural back. ground, race as well as econornic status. 1674 normal Korean children aged from 5 to 12 were tested...
Clinical Observations of Meningitis.
Byoung Hoon Lee, Hyung Keun Nam, Myung Ik Lee, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(2):180-190.   Published online February 28, 1989
The 267 cases of meningitis were observed at National Medical Center between Jan. 1st 1979 and May 31, 1986. The results were as follow; 1) In BM and TM sexual difference was not notice, but male was more in AM. 2) In BM infancy was the most common, but school age was common was AM. 3) Most cases developed during spring in BM and TM...
A Case of Child Desquamative Interstitial Pneumonia.
Woo Taek Kim, Hyoung Doo Lee, Yung Tak Lim, Hee Joo Jeon, Hee Joo Park, Chan Yung Kim
Clin Exp Pediatr. 1989;32(1):92-100.   Published online January 31, 1989
Desquamative interstitial pneumonia (DIP) is a variant of idiopathic interstitial pneumonias, but characteristicalIy has massive desquamation and proliferation of alveolar cells into the distal air space with minimal fibrosis of the alveolar wall. DIP seems to have better response to corticosteroid and benign prognosis than idiopathic interstitial pneumonia. We experienced one case of 6-year old girl who showed typical picture of DIF on lung...
Clinical Study of Patients with Benign Rolandic Epilepsy(BRE).
Seung Koog Kim, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(1):62-66.   Published online January 31, 1989
BRE, probably the commonest varierity of partial epilepsy in childhood has 6 characteristics; it occurs in children, without neuropsychiatric antecidents, never related to progressive cerebral lesion, interictal EEG shows Rolandic spikes, the seizure are varied and there is always recovery in puberty at the latest. We reviewed 70 patients with BRE to observe the age and sex distribution, EEG findings, clinical sign and symptoms, treatment...
The Direct Coombs Test and Heat Elution Test in ABO Incompatible Hemolytic Disease of the Newborn.
Kook In PArk, Chul Lee, Ran Namgung, Dong Gwan Han, Kir Young Kim
Clin Exp Pediatr. 1988;31(12):1633-1640.   Published online December 31, 1988
The clinical study on 28 cases of ABO HDN who were diagnosed at Pediatric Department of Severance hospital and Yong Dong Severance hospital, Yonsei University for last 5 months was. And in these cases, heat elution test in combined with direct Coombs test using standard techniques were performed to evaluate the clinical significance of serological diagnosis. The following results were obtained. 1) Of 28 ABO HDN...
Two Cases of Allergic Rhinitis in Children Diagnosed by Youlten's Peak Nasal Inspiratory Flow (PNIF) Meter.
Yil Sub Lee, In Suck Ryu, Kyu Eun Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(11):1527-1532.   Published online November 30, 1988
Two asthmatic children associated with allergic rhinitis were performed nasal provocation test with various allergens which were detected by allergic skin test. The degree of nasal obstruction induced by allergens were measured with Youlten’s Peak Nasal Inspiratory Flow (PNIF) meter and Red top,Trichophyton and Sagebrush were known as causative allergens in case 1, and Chrysanthemum was detected as causative allergen in case 2. The...
A Case of 4P-Syndrome.
Hong Kyu Lee, Sung Sik Lee, Soon Il Lee, Young Seok Lee, Kweon Ha Son
Clin Exp Pediatr. 1988;31(10):1366-1370.   Published online October 31, 1988
The first short arm deletion syndrome in human was described by Lejeune et al. in 1963. This has been labelled the 5p- syndrome. It was given the name ‘cri du chat` because of the characteristic kitten like cry of these patients. Two years later, Wolf et al. demonstrated a second short arm deletion syndrome which had no kitten like cry, but had characteristic...
Comparison of the Effects of Portacaval Shunt and Dietary therapy in Type I Gyocogen Storagy Diseases(GSD).
Dong Hyun Ju, Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1988;31(6):762-771.   Published online June 30, 1988
Type I GSD is a metabolic disease resulted from defective glucose-6-phosphatase activities in liver, kindey and intestine. They are characterized by growth retardation, enlargement of liver and kidney, hypoglycemia, hyperuricemia, and hyperlipidemia. Various methods were suggested for the management of GSD. They are night-time nasogastric feeding of glucose solution with frequent day-time feeding, intravenous hyperalimentation, cornstarch therapy end-to-side portacaval shunt, etc. In this study, the effects...
Case Report
A Case of Renal Candidiasis Associated with Type I Diabetes Mellitus.
Shin Heh Kang, Jae Seung Lee, Duk Hi Kim
Clin Exp Pediatr. 1987;30(6):677-683.   Published online June 30, 1987
We have experienced a case of renal candidiasis in type I DM (IDDM). The patient was a 15-year old girl who suffered from type I DM since 3 years earlier with development of retinopathy, cataract & renal failure. Ultrasonic examination revealed multiple fungus balls in renal pelvis & urinary bladder. Candida tropicalis was cultured from fungus balls passed during urination. A brief...
Original Article
Significance of Brain CT in Children with Meningitig.
Myeong Yeon Lee, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(6):640-650.   Published online June 30, 1987
This study was undertaken to evaluate the significance of brain CT in children with meningitis. The findings of brain CT in 71 children with meningitis were evaluated in relation to the clinical outcome. We divided 71 cases into 5 groups according to clinical outcome on discharge, that is, Group I: Recovery. Group II: Discharge with improvement. Group III: Discharge with residual sequalae. Group IV:...
A Case of Congestive Splenomegaly(Banti Syndrome) with Hypersplenism.
Hyun Mo Cheong, Jae Kwang Hong, Joon Taek Park, Jung Sik Min, Chang Hee Choi, Seung Hye Ahn, Sang Chull Kim
Clin Exp Pediatr. 1987;30(4):416-421.   Published online April 30, 1987
The authors experienced a case of hypersplenism in a 12 year-old male patient with the chief complaints of nasal bleeding and palpable mass on LUQ of abdomen. The patient had splenomegaly, leukopenia, and thrombocytopenia. He had high portal venous pressure of about 340 mmH20 and the splenoportography showed non-visualized portal vein and tortuous vessels suggesting portal vein obstruction. Splenectomy was done and his symptoms...
Case Report
Partial Trisomy10(q22~q26).
Hyung Chai Kang, Sung Myun Woh, Dong Whan Lee, Sang Jhoo Lee, Shin Yong Moon
Clin Exp Pediatr. 1986;29(12):1382-1386.   Published online December 31, 1986
Partial trisomy 10(q22-q26) is a extremely rare chromosomal anomaly. The authors experienced a case of this syndrome in a female newborn infant. She showed prominent occiput, flat face, blepharophimosis, hypertelorism, lowset ears, micrognathia, high-arched palate, simian crease on Lt. palm & overlapping of the 5th finger over the 4th finger, relatively great big toe, and single umbilical artery.Chromosomal study showed the abnormal chromosome...
A case of Unilateral Absence of Pulmonary Artery.
Kwang Sin Joh, Dong Soo Kim, Chul Joo Ryu, Shin Heh Kang, Sung Kyu Lee, Ki Young Lee, Dong Shik Chin
Clin Exp Pediatr. 1986;29(5):559-563.   Published online May 31, 1986
Unilateral Absence of Pulmonary Artery(UAPA) is a rare disease. It is characterized by no specfiic cardiopulmonary symptoms in general. We experienced a case of UAPA in a 9 year-old female patient with the chief complaint of abnormal chest Xray finding. Lung perfusion scan, cardiac catheterization with pulmonary and aortic angiography confirmed the diagnosis of right side UAPA.
Original Article
Change of Pulmonary Function after Exercise Loading Test and Preventive Measures on Exercise-induced Asthma in Chlidren.
Ki Yung Lee
Clin Exp Pediatr. 1986;29(3):277-286.   Published online March 31, 1986
143 cases(106 males, 37 females) with asthmatic children (aged from 54/i2 to 144/i2 year old) were performed pulmonary function test before and after exercise to detect exerciseinduced asthma (El A). If peak expiratory flow rate(PEFR), checked with Wright’s peak flowmeter, decreased 15% cr more after exercise loading test (up and down stair method for 6 minutes), the result was considered to...
Case Report
A Case of Osteogenesis Imperfecta.
Kwang Wook An, Chull Zoo Jung, Hyo Seop Joo, Seung Woo Moon
Clin Exp Pediatr. 1986;29(1):84-87.   Published online January 31, 1986
Osteogenesis imperfecta is an inherited disorders of connective tissue that affects the skeleton, ligament, sclera, and dentin. Characterized clinical manifestation are multiplefracture, blue sclera, deafness, joint laxity, thin skin, and odontogenesis imperfecta. We experienced acase of osteogenesis imperfecta in a one day old male newborn who chiefly complain respiratory distress, triangular shaped head and fracture and deformity of lower extremity....
A Case of Primary Lung Cancer(Squamous cell ca.) in Children.
Soo Ryun Choi, Choong Hyun Kim, Soon Ok Byun, Ji Sub Oh, Sung Kyun Im, Ok Ji Park
Clin Exp Pediatr. 1985;28(12):1256-1260.   Published online December 31, 1985
We have experienced a case of primary lung cancer (squamous cell ca.) in a 15 years-old boy who presented with productive coughing and mild fever. The diagnosis was made through thoracic roentgenogram, thoracotomy, and biopsy. A brief review of the related literature is given.
Two Case of Watson-Alagille Syndrome.
Heon Seok Han, Soo Heum Lim, Young Sun Kim, Jeong Kee Seo, Hyung Ro Moon
Clin Exp Pediatr. 1985;28(10):1047-1051.   Published online October 31, 1985
Watson-Alagille syndrome (Arteriohepatic dysplasia, Syndromatic paucity of interlobular bile duct), a disease characterized by chronic liver disease, characteristic facies, cardiova scular abnormalities, and vertebral arch abnormalities has paucity of interlobular bile ducts on histologic examination of liver. We experienced two cases of Watson-Alagille syndrome in a 7-month-old male infant and a 12-month-old male infant who had the chief complaint of...
A Case of Craniofacial Dysostosis(Crouzon's Disease).
Song Tae Kim, Yong Sang Yoo, Yong Youun Choi
Clin Exp Pediatr. 1985;28(10):1027-1031.   Published online October 31, 1985
We experienced a case of Crouzon* s disease in a 11 year 8 month-old boy with chief complaints of facial deformities and progressive impairment of visual acuity. Physical examination showed craniosynostosis, bilateral exophthalmos, external strabismus, birdlike beaked nose, high-arched palate, hypoplasia of maxilla, prognathism of mandible and dental malocclusion. The review of the literature was made briefly.
Original Article
Bone Marrow Cell Culture(GM-CFU) in Anaplastic Anemia of Children.
Jae Sun Jung, Chang Yee Hong
Clin Exp Pediatr. 1985;28(9):888-898.   Published online September 30, 1985
Bone marrow cell cultures (GM-CFU) were performed in the 15 cases of children with aplastic anemia and the correlation with the clinical course were investigated. They have been treated with androgen with or without low dose prednisone and supportive care. Bone marrow cell cultures from 8 children without any evidence of aplastic anemia were performed as a control. 1)In control...
Case Report
A Case of Congenital Nonspherocytic Hemolytic Anemia.
Tae Sook Kim, Sang Bae Jeon, Bok Yang Pyun
Clin Exp Pediatr. 1985;28(6):597-603.   Published online June 30, 1985
We observed a case of congenital nonspherocytic hemolytic anemia who was a 24 month old boy with the signs of jaundice 技 pallor. Evidences of the same disease was also found in the patient' s elder brother & father. We diagnosed these cases by history & physical examination, peripheral & B.M. blood smears, osmotic fragility test, autohemolysis test and etc. A...