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Original Article
Allergy
Asthma predictive index as a useful diagnostic tool in preschool children: a cross-sectional study in Korea
Dong Hyeon Lee, Ji-Won Kwon, Hyung Young Kim, Ju-Hee Seo, Hyo-Bin Kim, So-Yeon Lee, Gwang-Cheon Jang, Dae-Jin Song, Woo Kyung Kim, Young-Ho Jung, Soo-Jong Hong, Jung Yeon Shim
Clin Exp Pediatr. 2020;63(3):104-109.   Published online November 8, 2019
Question: Is physician-diagnosed current asthma in preschool children associated with the asthma predictive index, atopic sensitization, or pulmonary function test?
Finding: Physician-diagnosed current asthma in preschool children was associated with the asthma predictive index, but not with spirometry, methacholine provocation test, fractional expiratory nitric oxide level, and atopic sensitization.
Meaning: Physician-diagnosed asthma in preschool children may be different from classic atopic asthma in school children or adolescents.
Gastroenterology
Dietary habits and gastroesophageal reflux disease in preschool children
You Jin Choi, Eun Kyo Ha, Su Jin Jeong
Clin Exp Pediatr. 2016;59(7):303-307.   Published online July 31, 2016
Purpose

To identify the relationship between dietary habits and childhood gastroesophageal reflux disease (GERD) in preschool children.

Methods

We performed a questionnaire study to analyze the relationship between dietary habits and GERD in 85 preschool children with GERD and 117 healthy children of the same age.

Results

Irregular and picky eating were more p–revalent in the GERD group than in the control group (odds ratio...

Review Article
Association of wheezing phenotypes with fractional exhaled nitric oxide in children
Jung Yeon Shim
Clin Exp Pediatr. 2014;57(5):211-216.   Published online May 31, 2014

Asthma comprises a heterogeneous group of disorders characterized by airway inflammation, airway obstruction, and airway hyperresponsiveness (AHR). Airway inflammation, which induces AHR and recurrence of asthma, is the main pathophysiology of asthma. The fractional exhaled nitric oxide (FeNO) level is a noninvasive, reproducible measurement of eosinophilic airway inflammation that is easy to perform in young children. As airway inflammation precedes...

Original Article
Prevalence and comorbidity of allergic diseases in preschool children
Hyeong Yun Kim, Eun Byul Kwon, Ji Hyeon Baek, Youn Ho Shin, Hye Yung Yum, Hye Mi Jee, Jung Won Yoon, Man Yong Han
Clin Exp Pediatr. 2013;56(8):338-342.   Published online August 27, 2013
Purpose

Allergic disease and its comorbidities significantly influence the quality of life. Although the comorbidities of allergic diseases are well described in adult populations, little is known about them in preschool children. In the present study, we aimed to assess the prevalence and comorbidity of allergic diseases in Korean preschool children.

Methods

We conducted a cross-sectional study comprising 615 Korean children (age, 3...

Review Article
Early childhood wheezing: various natural courses and their relationship to later asthma
Dong In Suh, Young Yull Koh
Clin Exp Pediatr. 2012;55(8):259-264.   Published online August 23, 2012

Wheezing is one of the most frequent complaints that lead to the use of medical resources in younger children. Generally, wheezing is caused by bronchiolitis and resolves spontaneously without recurrence, but sometimes, wheezing can progress into asthma. Early data on the natural history of childhood wheezing was mostly obtained from retrospective reviews of medical records or from questionnaires, which made...

Original Article
Reference values for respiratory system impedance using impulse oscillometry in healthy preschool children
Jye Hae Park, Jung Won Yoon, Youn Ho Shin, Hye Mi Jee, Young Sun Wee, Sun Jung Chang, Jung Hwa Sim, Hye Yung Yum, Man Yong Han
Clin Exp Pediatr. 2011;54(2):64-68.   Published online February 28, 2011
Purpose

The normal values for lung resistance and lung capacity of children, as determined by impulse oscillometry (IOS), are different for children of different ethnicities. However, reference values there is no available reference value for Korean preschool children have yet to be determined. The aim of the present study was to determine the normal ranges of IOS parameters in Korean preschool...

Infantile risk factors for obesity in preschool children
Sun Ju Park, Jae Won Moon, Hyun Ji Kim, Min Jung Cho
Clin Exp Pediatr. 2008;51(8):804-811.   Published online August 15, 2008
Purpose : Childhood obesity is a problem that places a child at great risk for becoming an obese adult. To prevent obesity, it is important to focus on early life risk factors that may contribute to childhood obesity. The aim of this study is to find obesity-causing infantile risk factors in preschool children. Methods : A total of 223 children aged...
Review Article
Lung function tests in preschool children
Yong-Mean Park
Clin Exp Pediatr. 2007;50(5):422-429.   Published online May 15, 2007
Measurement of lung function is an integral component of respiratory physiology and of clinical assessment of lung diseases in school age children and adults. Pulmonary function test of infants and children under the age of 2 years have now been standardised and are being used both in research and as an adjunct to clinical management. By contrast, until recegntly, children...
Original Article
The alteration of the positive rate of cytomegalovirus IgG antibody among preschool period children
Se-Young Seo, Sang-Jun Park, Ja-Young Hwang, Seong-Hoon Hahn, So-Young Kim, Hyun-Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2006;49(1):51-55.   Published online January 15, 2006
Purpose : In order to evaluate the time of disappearance of cytomegalovirus(CMV) IgG antibodies from mothers, and the alteration of the positive rate of CMV IgG antibodies among preschool period children, we investigated the positive rate of CMV antibodies among preschool children. Methods : We studied 391 children who visited the Department of Pediatrics from March, 2001 to February, 2004. We...
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