Clinical and Experimental Pediatrics

Review Article

Nephrology (Genitourinary)

Kidney complications associated with COVID-19 infection and vaccination in children and adolescents: a brief review

Hee Sun Baek, Min Hyun Cho

Clin Exp Pediatr. 2023;66(10):424-431. Published online June 28, 2023

Several observational studies have shown that acute kidney injury affects up to 46% of children and adolescents who develop severe postinflammatory responses, such as multisystem inflammatory syndrome in childhood, due to coronavirus disease 2019 (COVID-19). Although causality has not been established, some cases of glomerulopathy or nephrotic syndrome occurring after COVID-19 infection or vaccination have been reported. Therefore, kidney complications associated with these conditions in children and adolescents warrant attention.

DOI: https://doi.org/10.3345/cep.2023.00738

Original Article

Nephrology (Genitourinary)

Variation in clinical usefulness of biomarkers of acute kidney injury in young children undergoing cardiac surgery

Hee Sun Baek, Youngok Lee, Hea Min Jang, Joonyong Cho, Myung Chul Hyun, Yeo Hyang Kim, Su-Kyeong Hwang, Min Hyun Cho

Clin Exp Pediatr. 2020;63(4):151-156. Published online February 5, 2020

Web of Science 3 Crossref 5

Question: Can clinical usefulness of biomarkers of acute kidney injury vary on the clinical circumstances?
Finding: In young children undergoing cardiac surgery, urine KIM-1/Cr level peaked at 24 hours with significant difference from baseline level and was significantly higher at 6 hours in the AKI group. However, urine NGAL/Cr and IL-18/Cr levels showed no specific trend with time for 48 hours after cardiac surgery.
Meaning: Urine KIM-1/Cr concentration could be considered a good biomarker for early AKI prediction after open cardiac surgery in young children.

DOI: https://doi.org/10.3345/cep.2019.00913

Renal involvement in children and adolescents with inflammatory bowel disease

Hea Min Jang, Hee Sun Baek, Jung-Eun Kim, Ju Young Kim, Yeon Hee Lee, Hee Yeon Cho, Yon Ho Choe, Ben Kang, Byung-Ho Choe, Bong Seok Choi, Min Hyun Cho

Clin Exp Pediatr. 2018;61(10):327-331. Published online September 12, 2018

Crossref 6

Purpose: The incidence of inflammatory bowel disease (IBD) is rapidly increasing, and several reports have described the renal complications of IBD. We sought to evaluate the clinical manifestations of renal complications in children with IBD in order to enable early detection and prompt treatment of the complications. Methods: We retrospectively reviewed the medical records of 456 children and adolescents aged <20...

DOI: https://doi.org/10.3345/kjp.2018.06485

Initial steroid regimen in idiopathic nephrotic syndrome can be shortened based on duration to first remission

Hee Sun Baek, Ki-Soo Park, Hee Gyung Kang, Cheol Woo Ko, Min Hyun Cho

Clin Exp Pediatr. 2015;58(6):206-210. Published online June 22, 2015

Purpose

The use of a 12-week steroid regimen (long-term therapy, LT) for the first episode of idiopathic nephrotic syndrome (NS) reportedly induces a more sustained remission and lower relapse rate than previous regimens, including an 8-week steroid regimen (short-term therapy, ST). Here, we assessed the potential for selective application of 2 steroid regimens (LT vs. ST) based on the days to...

DOI: https://doi.org/10.3345/kjp.2015.58.6.206

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Cited By 13	Etiological and pathophysiological enigmas of severe coronavirus disease 2019, multisystem inflammatory syndrome in children, and Kawasaki disease

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