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Purpose : The neonate is susceptible to severe and overwhelming bacterial infections. One of the most important deficiency in the neonatal host defense system seems to be quantitative and qualitative deficiency of the myeloid and the phagocytic system. Granulocyte colony-stimulating factor(G-CSF) has been shown to induce neutrophilia and enhance mature effector neutrophil function. We examined serum levels of G-CSF in... |
Purpose : To examine the clinical effects of early dexamethasone treatment from postnatal age of 1 week to ventilated preterm infants with respiratory distress syndrome. Methods : 14 one-week-old ventilator-dependent infants were enrolled. Seven received dexamethasone and another 7 did not receive. The doses of dexamethasone used were 0.25mg/kg twice daily for 3 days, 0.125mg/kg twice for 1 day, then 0.125mg/kg... |
Purpose : Fever in newborn might be an indicator of serious bacterial infection. Differentiating environmental from disease-related temperature elevations in newborn is clinically important, because neonate with environment-related temperature elevation might be subjected to an unnecessary work-up to detect occult disease. But there are exists no consistent conclusions about environmental effect in previous literatures. We prospectively evaluated the effect of... |
Purpose : We investigated whether there are independent intradaily changes in bilirubin levels in normal neonates. Methods : During the period of January 1996 till July 1996, 100 healthy newborn infants were studied for at least 3 consecutive days. Starting from the third day of life, consistent intradaily changes of bilirubin concentration were observed. And obstetric history, birth history, weight change at 3 days were... |
Purpose : We report clinical features and viral studies on 153 children with aseptic meningitis in the Pusan area in 1996 and compare the results of this study with those of other reports in 1990 and 1993. Methods : One hundred fiffy-three children with aseptic meningitis who have been admitted to the Department of Pediatrics, St. Benedict Hospital between July and October 1996 were... |
Purpose : This study was performed to evaluate seropositivities in term pregnant women and their neonates, and the transplacental transfer rate of maternal mumps and rubella- specific IgG from term pregnant women to their neonates. Methods : During Jun. 1, 1994 to Mar. 31. 1995, we collected 44 pairs of sera from pregnant women and their neonates in Anam Hospital of Korea University Medical... |
Purpose : We experienced an outbreak of hepatitis A in Taejon, Korea for the summer of 1996. Recently a shift in hepatitis A incidence from children to adults has been well noted in Korea. For the purpose of possible measures in preventing hepatitis A, we studied a seroepidemiology of hepatitis A in Taejon. Methods : We measured IgG anti-HAV antibody(HAVAB MEIA, Abbott) from 722... |
Purpose : Many different conditions result in pleural effusions(PEs) and making the differential diagnosis of PE is difficult. The purpose of the present study was to document the change of incidence and compare the etiologies of PEs with regards to age, the sidedness and characteristics of PE. Methods : During the 10-year period from 1986 to 1995, thoracentesis was performed in 197 children with PEs... |
Purpose : Early diagnosis of foreign body aspiration and removal of the inhaled material may save the patient from chronic illness and may prevent serious complications. At present the diagnostic problems of bronchial foreign bodies are being solved by using the lung scanning technique. Therefore, we investigated the clinical study and diagnositic value of the lung perfusion scan in foreign body aspiration. Methods : Eighteen... |
Purpose : Syncope is not rare and is caused by various conditions ranging from common physiologic derangements to life-threatening conditions. However, there are limited reports regarding syncope in children. We retrospectively analyzed our experiences of the syncope in children. Methods : Retrospective analysis of the medical records of patients with syncopal episodes between October 1985 and June 1996. Results : Sixty-eight patients(male; 36, female; 32,... |
Purpose : To assess whether pretreatment IGF-I SDS and pretreatmental bone age are useful indicators in the response of rhGH therapy in children with GH deficiency(GHD), the relationship between pretreatment IGF-I SDS, delay in bone age and the growth response during the first year of rhGH treatment was analyzed. Methods : This study included 12 children with GHD. We measured IGF-I levels by RIA... |
Purpose : The release of histamine from human basophils is controlled by an intrinsic, as yet unidentified, cellular property termed “releasability.” We carried out this study to ascertain whether there was any difference in the releasability of basophils from asthmatic children compared to those from normal children. We intended also to clarify the correlation between the releasability and the atopic status of asthma. Methods :... |
Purpose : Methylenetetrahydrofolate reductase is an important enzyme in homocysteine metabolism. Since the identification of the gene locus and mutation of methylenetetrahydrofolate reductase, an increasing number of reports have suggested that elevated levels of homocysteine were associated with various kinds of arteriovascular disease and neural tube defect. Our research plans to investigate whether elevated levels of homocysteine are more common with neural tube defect and... |
A 5-year-old male patient was admitted due to fever, and right upper abdominal pain for 2 weeks. He showed severe right upper quadrant tenderness on palpation, hepatomegaly 5 cm below the right costal margin, no mass, and no splenomegaly. On biochemical studies, ALT was 380IU/ml, AST 462IU/ml, alkaline phosphatase 1,069IU/ml, γGTP 239IU/ml, and total bilirubin 2.1mg/dl. Endoscopic retrograde cholangiopancreatography (ERCP) showed cylindrical dilatations of... |
Q fever is an important zoonosis caused by the rickrttsial organism, Coxiella burnetii. It is a very contagious organism which humans can contact by inhaling aerosolized organisms. Most commonly it leads to an acute flu-like illness. The diagnosis is usually confirmed serologically using a complement fixation or microimmunofluorescence test. Previous reports suggest that case -to - case in men is rare. We report person-to-person... |
An one-day-old female patient was admitted due to marked abdominal distension, cyanosis, right upper quadrant mass, and respiratory failure since birth. We applied ventilator and supportive care immediatly. However, 4 days later, she was dead due to respiratory failure and hemorragic complication. The radiographic finding showed a huge intra-abdominal mass anterior to the intestine. Autopsy findings showed a huge single cystic tumor in the... |
Disseminated intravascular coagulation(DIC) occurs rarely but can cause death in patients with juvenile rheumatoid arthritis(JRA), especially in the systemic type. The reports of DIC complicating JRA have increased recently. We experienced a 13 - year - old female patient with systemic JRA who died of DIC. The patient had been managed with aspirin, steroid, nonsteroidal anti-inflammatory drug for 7 years,... |