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The study was designed to evaluate the effect of vitamin E on hemolytic anemia of premature infants. Sixty infants delivered in Cheil Hospital from March 1987 to December 1988 with birth weight below 2500 gm or gestational age below 37 weeks were studied. Thirty infants received oral vitamin E 25 IU/day until their birth weight doubled. Thirty infants served as control. The results were... |
A clinical assessment of 25 patients with neonatal cholestasis caused by cytomegalovirus infection who were admitted to the Department of Pediatrics, Yonsei University College of Medicine from January 1983 to July 1988 was performed. The results were as follows: 1) The patients with neonatal cholestasis caused by cytomegalovirus infection were 19% of the total patients with neonatal cholestasis from January 1983 to July 1988 and were... |
Asymptomatic human rotavirus (HRV) infection rate was studied by comparing the rate of HRV excretion in diarrhea cases with that in nondiarhea group of children under preschool age. HRV antigen in stool was detected by enzyme-linked immunosorbent assay (ELISA) from children under 6 years of age who were admitted to Pediatric Department of Chung-Ang University Medical Center from November 1988 to mid-April 1989. 1) HRV antigen... |
Intussusception is an invagination of a segment of the gastrointestinal tract into an adjacent segment. It is the most common cause of acquired intestinal obstruction during infancy and early childhood. We compared the results of treatment with Barium Enema in 33 cases with that of Controlled Air Insufflation in 31 cases from January, 1985 to December, 1987. The results were as follows: 1) In age incidence, 86%... |
The 12 cases of Wilson disease younger than the age of 18 years were observed at Severance hospital between Jan. 1980 and July 1988 and we obtained following results. 1) The mean age was 14 years old and male to female ratio was 2:1 2) The younger the patient, the clinical symptoms predominantly manifested hepatic dysfunction and the older patient manifested neurologic symptoms. 3) Kayser-Fleischer’s ring was the... |
The False tendon is an anomalous chordae tendinae which attaches to abnormal sites in left ventricle. We studied the incidence of false tendon and relationship of the false tendon, functional murmur and arrhythmias using echocardiography. The results were as follow; 1) We found false tendons in 42 cases of total 307 cases, 13.6% 2) In group I (the patients who have congenital heart disease), the incidence of... |
We made a clinical study on 31 cases of histiocytosis X who had been admitted to the Dept, of Ped. of S.N.U.C.H. from Jan. 1981 to Dec. 1987. Among 31 cases, 28 patients received chemotherapy to include prednisolone, vinblastine, methotrex- ate and cyclophosphamide as induction therapy, and 6-mercaptopurine, methotrexate and cyclophos- phamide as maintenance therapy. The results obtained were as follows. 1) The sex incidence revealed male... |
Total of eighteen children with orthostatic proteinuria were evaluated for clinical characteristics. The development of renal or urologic diseases were monitored on these subjects for 1 year. The results were as following; 1) The number of children with transient orthostatic proteinuria and fixed orthostatic proteinuria were 7(39%) and 11(61%), respectively. 2) In children with fixed and reproducible orthostatic proteinuria, mild proteinuria were noted in 73% but no massive... |
We studied 11 cases of minimal change nephrotic syndrome randomly selected among 16 cases of minimal change nephrotic syndrome who were proved by kidney biopsy at department of pediatrics, National Medical Center during the period of January 1985 through December 1987. These patients were studied serially at 3 different stages in their clinical course. These were stages of edema formation, diuresis and remission, respectively. The... |
Serum concentrations of total triiodothyronine (T3) and thyroxine (T4) as well as serum thyroid- stimulating hormone (TSH) were measured in 108 patients with childhood epilepsy taking anticonvul- sants and in 54 normal healthy children as control group. Of these 108 patients, 23 were treated with carbamazepine alone, 17 were phenytoin alone and the rest 68 were treated with combination of two or more drugs... |
Paraquat is a widely used herbicide and its poisoning in human induces acute renal failure, hepatic dysfunction, progressive respiratory failure, oral cavity ulcer and cardiac manifestations with high mortality rate. We experienced a case of paraquat poisoning in a 12 years old child who revealed acute renal failure, pneumothorax, subcutaneous emphysema, pneumomediastinum and died 44 hours at acciden- tal ingestion of paraquat solution inspite of... |
The congenital posterior choanal atresia is an uncommon, but not rare, disorder that may threaten the newborn’s existence or give rise to chronic symptoms. As many as 50% of patients with choanal atresia have other associated anomalies. We experienced a case of congenital posterior choanal atresia without associated anomaly in 6 day old female baby. The patient was hospitalized due to the main symptoms... |
The development of respiratory management of the newborn has improved the survival rates of respiratory distress syndrome in these two decades. But the incidence of complication associated with this management has been increased. Although the pathogenesis of bronchopulmonary dysplasia has not been clearly established yet, bronchopulmonary dysplasia is one of the major complication of the mechanical ventilation. There are several factors in the development of... |
Hypertrophic cardiomyopathy is defined as a disorder of heart muscle of unknown cause or association, and is functionally characterized by a diastolic failure of the left ventricle due to loss of its normal distensibility. We subsequently experienced an 18 day old female newborn infant who had suffered from dyspnea, cyanosis and congestive heart failure since a few days after birth. She died of progressive... |
Kostmann Syndrome is an uncommon disorder, which is characterized by recurring infections, begining soon after birth, arid by abscence of granulocyte in the peripheral blood. The authors experienced a case of Kostmann Syndrome in a 5 months old boy who had suffered from recurrent infection since 7 days of age. We diagnosed this case by history, physical examina- tions, culture of bone marrow stem... |
Glanzmann’s thrombasthenia is rare congenital bleeding disorder of autosomal recessive trait. We experienced two cases of Glanzmann’s thrombasthenia in brother. The mother and elder brother had no history of bleeding tendency. But 10 year-old and 7 year-old younger brothers had frequent epistaxis, gum bleeding and easy bruisability. On platelet aggregation test, mother and elder brother appeared normal responses, but the younger brothers appeared no responses... |
We experienced an interesting case of Henoch-Schönlein purpura associated with scarlet fever in a 10-year-old girl. Typical two rashes representing Henoch-Schönlein purpura and scarlet fever appeared simultaneously. Fine erythematous maculopapular eruptions (goose-skin appearance) and straw-berry tongue, characteristic of scarlet fever, were present above the pelvis with varing sized purpuras, characteristic of Henoch-Schönlein purpura, below the pelvis. |
Dandy-Walker syndrome is a developmental disorder of the brain associated with hydrocephalus, possterior fossa cyst and maldevelopment of the cerebellar vermis and is a result of outlet obstruction of the fourth ventricle. We experienced a case of a 6 day old male neonate who presented macrocephaly which revealed marked dilated fourth & lateral ventricle, large posterior fossa cyst and hypoplastic cerebellum, no vermis on Brain... |
We experienced a case of Guillain -Barré syndrome in a 12-year-old female patient who had progressive motor weakness and showed rapid recovery with plasmapheresis and supportive therapy in acute stage. A brief review of the related literature was added. |
Thanatophric dysplasia have a prominent forehead, depressed nasal bridge, and bulging eyes. The limbs are extremly short and held extended from the body. The chest is small and pear-shaped. Affected infants are hypotonic and lack primitive reflexes. Most affected infants are still born or die within hours of birth. Two cases of thanatophoric dysplasia are presented with gidelines for diagno- sis. A review of... |