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Volume 40(11); Nov 1997
Medical Lecture Course
Significance of Clinical Pharmacology in Pediatrics
Min Soo Park
J Korean Pediatr Soc. 1997;40(11):1495-1500.   Published online November 15, 1997
Clinical Lecture
Otitis Media and Sinusitis
Keun Chan Sohn
J Korean Pediatr Soc. 1997;40(11):1501-1507.   Published online November 15, 1997
Original Articles
Influences of the Intrapulmonary R→L Shunt on PaO2 and PaCO2 after Instillation of Exogenous Pulmonary Surfactant to Premature Neonates with Respiratory Distress Syndrome
Yoon Hyung Park, Sei Woo Chung, Seung Baik Han, Young Se Kwon, Ji Youn Kim, Woo Sik Cheong, Dae Hyun Lim, Byong Kwan Son
J Korean Pediatr Soc. 1997;40(11):1508-1519.   Published online November 15, 1997
Purpose : We are inclined to analyze the relationship between the intrapulmonary right-to-left shunt and the PaO2/PaCO2 after endotracheal single-dose surfactant instillation to premature neonates with respiratory distress syndrome within 6 hours after birth. Methods : From Jan. 1993 to Jun. 1995, we have conducted a clinical trial of surfactant replacement therapy to the premature neonates with respiratory distress syndrome at the neonatal intensive care unit...
Neonatal Facial and Cry Responses to Invasive and Non-invasive Procedures
Seon Hwa Seo, Young Pyo Chang
J Korean Pediatr Soc. 1997;40(11):1520-1528.   Published online November 15, 1997
Purpose : The evaluation of pain in neonates is difficult due to their limited means of communication. The aim of this study was to determine whether the behavioral reactions of facial action and cry provoked by an invasive pain-induced procedure could be discriminated from the reactions to a noninvasive pain-induced procedure in normal full-term neonates. Methods : Thirty-six healthy full-term neonates received three pain-induced...
Nitroglycerin Treatment in Persistent Pulmonary Hypertension of the Newborn
Ji Sook Kim, Sung Sook Jeon, Son Sang Seo
J Korean Pediatr Soc. 1997;40(11):1529-1536.   Published online November 15, 1997
Purpose : Persistent pulmonary hypertension(PPHN) of the newborn has been treated with some vasodilators including tolazoline. But these drugs have many side effects, especially systemic hypotension . To investigate the usefulness of the nitroglycerin as a specific vasodilator with few side effects, this study was done. Methods : Nitroglycerin was administered within 1st one day after birth in 8 newborn infants who were diagnosed as...
Comparison of Antimicrobial Susceptibility of Nosocomial and Community-Acquired Pathogens in Children of Medium-Sized Hospital
Kil Soo Joung, Jae Kook Cha, Kon Hee Lee, Hye Sun Yoon, Wonkeun Song
J Korean Pediatr Soc. 1997;40(11):1537-1543.   Published online November 15, 1997
Purpose : We evaluated the identification and antimicrobial susceptibility patterns of nosocomial and community-acquired pathogens in children of the medium-sized hospital. Methods : The 357 bacterial strains isolated from Pediatric department of Dongsan Sacred Heart Hospital were examined the species identification and antimicrobial susceptibility test during the period of March to October 1996. Results : Fifty three strains(15%) of 357 strains were nosocomial pathogens. A...
Colonic Transit Time in Children with Recurrent Abdominal Pain
Je Woo Kim, Ki Sup Chung
J Korean Pediatr Soc. 1997;40(11):1544-1551.   Published online November 15, 1997
Purpose : Recurrent abdominal pain is defined as the presence of at least three discrete episodes of pain occurring over a period of 3 or more months. The reported prevalence is high up to 15% of school aged children. Mostly the pain results from functional dysmotility of the intestine but not much studies has been done. Thus we studied segmental colonic transit time(CTT)...
Endoscopic Removal of Foreign Bodies in Upper GI Tract in Children
Hae Jung Han, Sang Gil An, Yong Min Chung, Hee Sup Kim, Hann Tchah, Ho Jin Park
J Korean Pediatr Soc. 1997;40(11):1552-1558.   Published online November 15, 1997
Purpose : The foreing bodies in the upper GI tract are chiefly caused by accidental swallowing and rarely provoke symptoms. It is recommended to remove the foreign bodies if they produce symptoms or remain in GI tract for long duration or complications are expected to bring about. Nowadays the development of pediatric therapeutic endoscopy enables the removal of the foreign bodies in upper GI tract...
Diagnostic Value of 99mTc-DMSA SPECT in Children with Urinary Tract Infection
Jae Won Choi, Sung Ho Cha, Byoung Soo Cho, Duk Yoon Kim
J Korean Pediatr Soc. 1997;40(11):1559-1566.   Published online November 15, 1997
Purpose : The accurate identification of renal cortical defects in children with urinary tract infection is essential in reducing subsequent morbidity. Imaging of the kidneys with 99mTc-dimercaptosuccinic acid (DMSA) has been demonstrated as the sensitive method available for identification of renal cortical defects. Single photon emission computerized tomography(SPECT) has been suggested as a method by which the accuracy of identification of renal cortical defects can...
Role of Serum Ca and 1,25(OH)2D3 as Predictor in Bone Metabolism Abnormality by Chronic Medication of Anticonvulsant
Ho-Soo Kim, Hyun-Ho Kang, Sa-Jun Chung, Yong-Mook Choi
J Korean Pediatr Soc. 1997;40(11):1567-1571.   Published online November 15, 1997
목 적 : 항경련제의 장기복용에 의하여 저칼슘혈증, 구루병, 골연화증 등의 골대사 이상은 성 장기 소아의 중대한 문제점이 될 수 있으므로 조기발견 및 치료가 중요하다. 이에 본 저자들은 골대사 이상의 예측을 위한 지표로서 혈청 Calcium(이하 Ca), 1,25(OH)2D3에 대하여 연구를 시행하였다. 방 법 : 경희의대 소아과에서 경련성 질환으로 진단 받고 6개월 이상 항경련제를 복용한 48 명을 대상으로 하였다. 이들중 항경련제 단독복용은 37명, 두 가지 이상의 혼합복용군은 11명 이었으며,...
Immunophenotypic Analysis of Umbilical Cord Blood Stem Cells
Won Ho Kang, Tai Ju Hwang, Hoon Kook, Byung Ju Kim
J Korean Pediatr Soc. 1997;40(11):1572-1581.   Published online November 15, 1997
Purpose : Since umbilical cord blood (UCB), which used to be discarded, was found to be a source of enriched hematopoietic stem and progenitor cells, basic research to elucidate characteristics of UCB hematopoietic stem cells (HSCs) and its clinical application to bedside transplantation have been attempted. Moreover, stem cell transplantation (SCT) has expanded its role, not only in hematopoietic reconstitution, but in cancer therapy,...
Clinical Trial of 2g/kg/day of Intravenous Immunoglobulin Single Dose as Compared with 400mg/kg/day of Intravenous Immunoglobulin for 5days in Kawasaki Disease
Seok Hee Oh, Heung Tag Kim, Hae Jin Chech, Kyuchul Choeh
J Korean Pediatr Soc. 1997;40(11):1582-1587.   Published online November 15, 1997
Purpose : Since the effect of intravenous immunoglobulin (IVIG) therapy in Kawasaki disease was reported in 1984, the combined therapy of IVIG & oral aspirin has been popular. In early period, the protocol of 400mg/kg/day for 3-5 days of IVIG had been used, but rescently, the protocol of 2g/kg/day single dose has been preferred. So authers performed a clinical study to compare th efficacies...
Childhood Near-Drowning in Chinju
Hyang Ok Woo, Chan-Hoo Park
J Korean Pediatr Soc. 1997;40(11):1588-1595.   Published online November 15, 1997
Purpose : Drowning is the second most common cause of accidental death in children, exceeded only by motor vehicle accidents. The purpose of the present study was to investigate the prognostic factors of near-drowning in children, such as age, sex, season, site of submersion, and initial clinical or laboratory manifestrations, and to formulate preventive strategies for decreasing injuries by drowning. Methods : Sixty-one near-drowning children...
The Statistical Study of Patient with Acute Poisoning
Heung Pyo Kong, Kyoung Bae Park, Oh Kyung Lee, Kang Suh Park
J Korean Pediatr Soc. 1997;40(11):1596-1602.   Published online November 15, 1997
Purpose : The incidence of infectious disease, which has been the cause of death in pediatric period, was decreased. But, the opportunistic exposure to toxic substance shows a tendency to increase. We performed this study in order to find out preventive measures and the latest inclination of acute poisoning in childhood. Methods : From January 1985 to July 1996, 88 children with acute drug...
Case Reports
A Case of Type IV-4 Renal Tubular Acidosis
Young A Jo, Dong Un Kim, Yoon Kyung Lee, Byung Jun Choi, Jin Tack Kim, Ik Jun Lee
J Korean Pediatr Soc. 1997;40(11):1603-1607.   Published online November 15, 1997
Type IV renal tubular acidosis(RTA) is due to renal tubular bicarbonate wasting associated with mineralocorticoid deficiency. In its five subtypes, IV-4 is due to pseudohypoaldosteronism(PHA) evidenced by increased plasma renin and aldosterone. PHA is believed to result from distal tubular unresponsiveness to circulating aldosterone and has normal renal and adrenal fuction. Hypoaldosteronism can easily be suspected when the patient shows typical electrolyte imbalance (hyponatremia coupled with...
Pyomyositis of Pyriformis Muscle Caused by Vigorous Exercise and Acupuncture in a Healthy Boy
Joo Hun Choi, Seo Jeong Kim, Woo Hyun Ahn
J Korean Pediatr Soc. 1997;40(11):1608-1611.   Published online November 15, 1997
A case of pyomyositis of right pyriformis and iliacus muscle in a healthy 13 year old male patient is presented and discussed. Pyomyositis is a primary acute bacterial infection of large skeletal muscles, associated with abscess formation. Since pyomyositis has been reported mainly in tropical countries and is rare in temperate climates, the name ' tropical myositis' is often used. Outside the tropics, pyomyositis...
A Case of Pulmonary Artery Sling
Mi Hee Oh, Il Tae Whang, Ghee Young Jung, Doo Bong Lee
J Korean Pediatr Soc. 1997;40(11):1611-1615.   Published online November 15, 1997
Pulmonary artery sling is a rare vascular anomaly in which the left pulmonary artery arises from the right pulmonary artery and then traverses between the esophagus and the trachea toward the hilum of the left lung. Despite the availability of a corrective operation, the mortality rate remains very high due to the high incidence of associated obstructive anomalies of tracheobronchial trees. We experienced a...
A Case with Dysphagia Caused by Lower Esophageal Ring in Childhood
Su Eun Park, Hwang Jae Yoo, Cheol Hong Kim, Jae Hong Park
J Korean Pediatr Soc. 1997;40(11):1616-1620.   Published online November 15, 1997
Lower esophageal ring is unique disorder of the esophagus. It is composed entirely of mucosal fold, containing no muscle or scar tissue. It is one of the most common causes of dysphagia of adults, but an unusual cause of dysphagia in pediatric age group. This 14-year old male patient experienced progressive dysphagia for several years. Approximately 15 months prior to this visit, he began...
A Case of Congenital Insensitivity to Pain with Anhidrosis
Munhyang Lee, Nam Seon Beck, Dongkyu Jin, Yeon-Lim Suh
J Korean Pediatr Soc. 1997;40(11):1621-1626.   Published online November 15, 1997
Congenital insensitivity to pain with anhidrosies (CIPA) is one of the exceedingly rare hereditary sensory autonomic neuropathies (HSAN). There are five types of HSAN according to hereditary transmission, natural history, clinical manifestations, and pathologic findings. The CIPA corresponds to type IV and is characterized by episodes of recurrent fever with generalized anhidrosis, insensitivity to pain and temperature with self-multilation, and mental retardation. We report a 14...