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Volume 40(5); May 1997
Medical Lecture Course
Cyclin Dependent Kinase Inhibitors(CDKIs) and Genetic Alterations of CDKN2(p16-INK4A/MTS1) Gene in Hematologic Malignancies
Chang Hyun Yang
J Korean Pediatr Soc. 1997;40(5):593-599.   Published online May 15, 1997
Clinical Lecture
Urinary TractInfection in Childre
Su-Yung Kim
J Korean Pediatr Soc. 1997;40(5):600-606.   Published online May 15, 1997
Original Articles
Occurrence of Mycoplasma pneumoniae Pneumonia in Seoul, Korea, from 1986 to 1995
Jung-Yun Hong, Song-Yi Nah, Seung-Gon Nam, Eun-Hwa Choi, Jin-Young Park, Hoan-Jong Lee
J Korean Pediatr Soc. 1997;40(5):607-613.   Published online May 15, 1997
A Clinical Study on BCG Lymphadenitis
Jin Soo Hwang, Young Youn Choi, Jae Sook Ma, Tai Ju Hwang
J Korean Pediatr Soc. 1997;40(5):614-619.   Published online May 15, 1997
Purpose : We studied the incidence and clinical course of BCG lymphadenitis to investigate the BCG related problem. Subject and Methods: Three hundred and eighty-six infants received BCG vaccine (Pasteur-1173p2) in the Well Baby Clinic, Dept. of Pediatrics, Chonnam University Hospital from May 1993 and April 1994. Among them, twenty three infants developed regional lymphadenitis. We investigated the clinical course...
Epidemiology of Varicella in Korea Based on Pediatrician's Office Practice
Dong Jun Kim, Hyeon Soo Park, Sang Yun Lee, Kee Surk Park, Taik Kill Kim, Young Hoon Song, Jin Choi, Jin Woo Han, Young Suk Song, Tae Jin Park, Hong Kun Kim, Soo Yup Lee, Sun Ho Lee, Hak Won Kim, Sung Hee Oh
J Korean Pediatr Soc. 1997;40(5):620-628.   Published online May 15, 1997
Purpose : Although varicella outbreakes have frequently occured, the epidemiology of varicella in Korea has not well been delineated. Furthermore without enough investigation with regard to safety and efficacy of varicella vaccine in Korean population, thevaccine has begun to be used in healthy children. Therefore the authors analized the clinical features of patients diagnosed of varicella to aid in understanding...
Echocardiographic Study of the Ventricular Septal Defect with Subaortic Ridge
Kyeung Hee Moon, Pyoung Han Hwang, Chan Uhng Joo
J Korean Pediatr Soc. 1997;40(5):629-634.   Published online May 15, 1997
Purpose : The easy recognition and characterization of a discrete or fixed subaortic ridge by echocardiography provides a method for prospective study of the coexistence of ventricular septal defect(VSD) and subaortic ridge. In the presence of a VSD, a subaortic ridge may be clinically silent, but the obstruction can progress if the VSD is surgically or spontaneously closed. This study...
Nonoperative Treatment of PDA Using the Duct-OccludⓇ
Dong Woon Shin, Kyung Hee Lee, Heon-Seok Han
J Korean Pediatr Soc. 1997;40(5):635-640.   Published online May 15, 1997
Purpose : Among the several transcatheter devices of PDA occlusion, Rashikind device was the most extensively experienced, but it had risk of occluder embolism and incomplete occlusion of PDA, approximately 27%. The authors used Duct-OccludⓇ, made of 0.028 inch stainless steel coil. The coil is double cone-shape in released state, and used in streched condition through 4F implantation catheter for...
Intermediate Term Follow-up Results of Hypertrophic Cardiomyopathy in Children
Eun Jung Cheon, Chung Il Noh, Jae Young Lee, Sun Sung Park, Myung Ja Yun, Hong Ryang Kil, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
J Korean Pediatr Soc. 1997;40(5):641-649.   Published online May 15, 1997
Purpose : Hypertrophic cardiomyopathy(HCMP) is a primary cardiac muscular disease with high risk of sudden cardiac death. This study is performed to understand the clinical features of children with HCMP. Methods : Retrospective analysis of the medical records of the patients diagnosed at Seoul National University Children's Hospital between October 1985 and June 1996 was done. Excluded the patients who had...
A Study of Vascular Reactivity Change in Nephrotic Syndrome Children Using Plethysmography
Jae Won Shim, Byoung Hoon Yoo, In Suk Lim
J Korean Pediatr Soc. 1997;40(5):650-659.   Published online May 15, 1997
Purpose : The nephrotic syndrome is characterized by proteinuria, hypoproteinemia, edema and hyperlipidemia. These can change body homeostasis and cause hypertension. This study was designed to determine the relationship between the forearm vasodilating capacity and serum cholesterol level of nephrotic syndrome patients. Methods : 15 Nephrotic syndrome patients and 17 normal control children who visited Chung-ang University Youngsan Hospital from Sep....
The Efficacy of Routine Liver Function Test Follow Up in Epileptic Children
Dae Hun Pee, Hyung Joo Sohn, Young Kyoo Shin, Baik Lin Eun, Sang Hee Park, Soon Kyum Kim
J Korean Pediatr Soc. 1997;40(5):660-671.   Published online May 15, 1997
Purpose : Routine liver function test follow up is done in epileptic children receiving antiepileptic drugs to prevent hepatotoxicity induced by these drugs. But rarely seen are the abnormalities of liver function test, and seldomly are these abnormalities accompanied by the clinical manifestation. This study is carried out to assess the efficacy of routine liver function test follow up in...
Long-term Growth Response to Growth Hormone Therapy in Children with Growth Hormone Deficiency
Byung Churl Lee
J Korean Pediatr Soc. 1997;40(5):672-679.   Published online May 15, 1997
Purpose : The aim of this study was to evaluate the long-term growth response to growth hormone therapy in 18 children with naive growth hormone deficiency. Methods : The subjects of this study were aged 3-13.5 years and each patient continuously received GH(EutropinⓇ) 0.45-0.7IU/kg/week, intramuscularly or subcutaneously in 3-7 divided dose for up to 7 years. Standard auxologic assessment was carried...
Clinical Features of Adrenocortical Neoplasms
Jung-Eun Lee, So-Chung Chung, Duk-Hi Kim, Ho-Sung Kim
J Korean Pediatr Soc. 1997;40(5):680-689.   Published online May 15, 1997
Purpose : Adrenocortical tumors are uncommon in children and comprise only a small proportion of primary adrenal neoplasms. The biologic behavior of these tumors may be very difficult to predict, and their rarity has hindered identification of clinical characteristics. Patients with functioning tumors have excessive steroid hormone production, and the clinical manifestation depends on the predominant hormone produced. The detection of...
Production of Interleukin-1α and Tumor Necrosis Factor-α by Human Cord and Adult Blood Mononuclear Cells Stimulated by TSST-1 and LPS
Eun Ae Park, Kyung Hyo Kim, Gyoung Hee Kim
J Korean Pediatr Soc. 1997;40(5):690-700.   Published online May 15, 1997
Purpose : Immature immunological defens mechanism in the neonate may contribute to the high susceptibility to overwhelming sepsis. S. aureus TSST-1 and E. coli LPS known as one of the important pathogens of septic shock or toxic shock induce massive release of various cytokines, such as tumor necrosis factor-alpha(TNF-α) and interleukin-1α(IL-1α) produced from peripheral blood mononuclear cells(PBMC). In contrast, limited...
Dermatophagoides Pteronyssinus Specific IgG-subclass Antibodies in Allergic Children
Soo Ja Hwang, Kyung Hyo Kim, Young Mi Hong
J Korean Pediatr Soc. 1997;40(5):701-707.   Published online May 15, 1997
Purpose : Although immunoglobulin E play a major role in immediate hypersensitivity reactions, some reaginic activity is associated with IgG. Part of the reaginic activity is associated with IgG1, IgG4. In contrast with this reaginic activity of IgG4, allergen-specific IgG4 antibody is allergen neutralizing antibody and contribute to the benificial effect of immunotherapy. The role of specific IgG antibody in allergic...
Case Reports
Four Cases of Pulmonary Artery Sling with Bridging Bronchus
Seung A Lee, Jung Yeon Shim, Young Hwue Kim, Jae Kon Ko, In Sook Park, Soo-Jong Hong, Chang Yee Hong
J Korean Pediatr Soc. 1997;40(5):709-715.   Published online May 15, 1997
Pulmonary artery sling with bridging bronchus is not only rare but also difficult to diagnose unless specially sought. When young infant suffers from prolonged or recurrent wheezing, possibility of underlying anomalies of the tracheobronchial trees or great vessels should be considered, even though bronchiolitis and gastroesophageal reflux are the most common causes. We experienced four cases of pulmonary artery sling with...
A Case of Spondyloepiphyseal Dysplasia Congenita
Hwang Jae Yoo, Su Eun Park, Sang Ook Park, Jae Hong Park, Su Yung Kim
J Korean Pediatr Soc. 1997;40(5):716-720.   Published online May 15, 1997
Spondyloepiphyseal dysplasia congenita is one of the osteochondrodysplasia, used to be diagnosed by clinical symptoms and radiologic findings. Clinical findings are short-trunk dwarfism, oval face, hypertelorism, short neck, kyphosis, lordosis, joint instability, coxa vara, pectus excuvatum, cleft palate, severe myopia, retinal detachment, deafness, and radiologic findings are thoracic kyphosis, lumbar lordosis, platyspondyly, anterior flaring of ribs, delayed ossification of head...
Pena-Shokeir I Syndrome in a Newbonrn Infant
Myung Gil Han, Kyu Young Kim, Dong Woo Son, Bo Young Yoon, Kyung Hee Park, Do Hyun Kim, Hyung Ro Moon
J Korean Pediatr Soc. 1997;40(5):721-725.   Published online May 15, 1997
Pena-Shokeir I syndrome is a multiple malformation syndrome displaying characteristics of camptodactyly, multiple ankylosis, severe muscle weakness, facial anomalies (low set ears, hypertelorism, depressed tip of nose), polyhydramnios, fetal growth retardation & pulmonary hypoplasia which are inherited by autosomal recessive trait. We experienced 1 case of Pena-Shokeir I syndrome in a neonate (41 weeks, 2.08Kg). This patient suffered from dyspnea. Respiratory...
A Treatment Case with PTCA in Osteal Stenosis of Takayasu's Arteritis
Tae Gyoun Park, Won Kyu Choi, Hae Yong Lee
J Korean Pediatr Soc. 1997;40(5):726-729.   Published online May 15, 1997
PTCA was performed in llgears old Takayasu’s arteritis patient with left coronary artery osteal stenosis. A balloon angioplasty catheter was introduced by a 7-F guiding catheter with a 0.14 steerable guide wire. The balloonings were approximately 60 and 80 seconds at each duration. The procedure was performed repeat twice. The stenotic lesion was improved after PTCA. After 2years PTCA, left...
Transcatheter Coil Closure of a Congenital Coronary Arterial Fistula
Hye Soon Kim, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Young Soo Yun
J Korean Pediatr Soc. 1997;40(5):730-734.   Published online May 15, 1997
Congenital coronary artery fistulas are rare congenital heart anomalies. Surgical closure of these fistulas was the therapy of choice till recently. The recent development of a new accurate coil-delivery system has enabled us to embolize the vessels. Percutaneous transcatheter coil embolization is a safe and effective approach to treating coronary artery fistulas and should be considered as the best treatment...