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Volume 37(8); Aug 1994
Original Articles
Effect of Glucocorticoid-Induced Hyperglycemia on Preventing Hypoxic-Ischemic Brain Damage by Dexamethasone in Neonatal Rat
Kook In Park, Tae Seung Kim, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Gwan Han
J Korean Pediatr Soc. 1994;37(8):1035-1047.   Published online August 15, 1994
Purpose : We evaluated the protective effect of dexamethasone (DX) administration on brain damage produced in a perinatal model of cerebral hypoxia-ischemia in the rat. Since hyperglycemia has been shown to reduce hypoxic-ischemic brain injury (HI) in immature rat, we investigated the role of glucocorticoid-induced hyperglycemia in the neuroprotective mechanism of DX. Methods : Hypoxic-ischemic brain injury in 7-day-old rats was...
A Study of Relation between Stable Microbubble Rating and Pulmonary Surfactant Concentration in vitro
Seong Yong Jung, Thi Hyung Park, Chong Woo Bae, Chang Il Ahn
J Korean Pediatr Soc. 1994;37(8):1048-1054.   Published online August 15, 1994
Respiratory distress syndrome (RDS) of preterm infants remains a significant cause of morbidity and mortality despite improvements in neonatal intensive care and artificial ventilatory techniques. After identification of the deficiency of pulmonary surfactant is major pathophysiologic basis in RDS, artificial surfactant replacement therapy in RDS was first successfully tested by Fujiwara and co-workers in 1980. Therefore, exogenous surfactant replacement produced exellent...
Morphologic Changes of Lung Parenchymal Tissue in Neonatal Rat Pups under Chronic Hyperoxia
Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
J Korean Pediatr Soc. 1994;37(8):1055-1064.   Published online August 15, 1994
We studied the effects of chronic hyperoxia (>95% oxygen for 14 days) in change of body weight, wet to dry ling weight ratio, and morphologic changes of lung tissue compared with that of room air (21% oxygen for 14 days) in Sprague-Dawley neonatal rat pups. The results were as follows: 1) In neonatal rat pups exposed to room air (normoxia group), body...
Incidence and Perinatal Risk Factors of Respiratory Distress Syndrome of Newborn
Yun Sil Chang, Beyong Il Kim, Jung-Hwan Choi, Chong Ku Yun
J Korean Pediatr Soc. 1994;37(8):1065-1077.   Published online August 15, 1994
Over a continuous 4-year period, from January 1989 till December 1992, 7,100 infants were born in Department of Obstetrics and admitted to Nursery or Neonatal Intensive Care Unit of Department of Pediatrics of Seoul National University Children's Hospital. Among them, 126 cases were diagnosed as respiratory distress syndrome (RDS) of newborn. The total incidence of RDS among all the newborns(inborn)was 1.77%....
A Study on Evolution of Lipoportein(a) in Newborns
Keun Haeng Cho, Young Sook Hong, Soo Won Lee, Soon Kyum Kim, Young Chang Tockgo, Han Kyeom Kim
J Korean Pediatr Soc. 1994;37(8):1078-1091.   Published online August 15, 1994
Lipoprotein(a) [Lp(a)] is considered an additional, independent and largely genetically determined risk factor for the development of premature coronary heart disease. Furthermore abnormal plasma lipoprotein patterns have been associated with increased risk for developing coronary heart disease. Among these lipoproteins, an increased concentration of serum Apo B and decreased level of Apo A are considered as major risk factors, together...
Clinical Observation of urinary Tract Anomalies
In Hee Jung, Hong Jin Lee, Sang Joo Han, Won Il Park, Kyung Ja Lee
J Korean Pediatr Soc. 1994;37(8):1092-1096.   Published online August 15, 1994
Urinary tract anomaly is the most common anomaly in childhood. We reviewed medical records of 45 patients who were confirmed urinary tract anomalies on radiologic studies as Chuncheon Sacred Hospital, from Dec. 1984 to Sep. 1992. We analyzed incidence and clinical characteristics of urinary tract anomalies. The results obtained were as follows: 1) The age distrtibution were: 17 cases (37.8%) under...
Identification of the Source of hematuria by the Ratio of the Urinary Erythrocyte MCV to That in Blood
Young Guk Kim, Gi Chan Lee, Keun Haeng Cho, Kee Hwan Yoo, Soon Kyum Kim
J Korean Pediatr Soc. 1994;37(8):1097-1103.   Published online August 15, 1994
The frequent occurrence of hematuria in children necessitates diagnostic evaluation. Hematuria may occur with either renal or lower urinary tract disease. Clarification of the etiology of hematuria, whether microscopic or gross, is facilited by localizing the site of bleeding to the kidney(glomerular) or the lower urinary tract (non-glomerular). The mean cellular volume (MCV) of urinary red blood cells (RBCs) of...
A Clinical and Pathological Study of Recurrent Hematuria in Childhood
Mi Jeong Kim, Jae Wook Ko, Young Jin Hong, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn
J Korean Pediatr Soc. 1994;37(8):1104-1110.   Published online August 15, 1994
The clinico-pathological observation was done on 28 children with recurrent hematuria, who had been admitted to the Pediatric ward of NMC from January 1981 to July 1991. The results were as follows; 1) Most of the children with recurrent hematuria were over 6 years of age (24 cases, 85.7%) and the sex ratio was about 2.5:1. 2) IgA nephropathy (17 cases, 60.7%) was...
A Study on Blood Lead Levels in Pediatric Inpatients
Young Ho Lee, Hyoung Shim Chang, Bong Keun Choi, Kyu Geun Hwang, Ahn Hong Choi
J Korean Pediatr Soc. 1994;37(8):1111-1115.   Published online August 15, 1994
Lead is one of the most widespredad environmental toxins and its poisoning in children was considered a rarity, usually resulting from unique circumstances such as inappropriate use of lead-based body cosmetics or direct administration of lead-containing folk medicines. The increasing concern about children with lower levels of lead exposure has developed, but there are no data regarding the mean blood...
Chronic Cough in Children
Bin Cho, Joon Sung Lee, Kyung Tai Whang, Sung Hoon Cho
J Korean Pediatr Soc. 1994;37(8):1116-1123.   Published online August 15, 1994
Chromic cough is a symptom frequently encountered by the pediatrician. Although most coughs are self-limited, chronic cough ofter proves to be a frustrating problem. This study was performed at Kangnam St. Mary's Hospital from January 1,1992 to December 31, 1992, and 83 children with chronic cough persisting for longer than 3 weeks was evaluated. We categorized these patients into 5...
Epstein-Barr Viral Hepatitis in Childhood
Soo Kyung Lee, Ki Sup Chung
J Korean Pediatr Soc. 1994;37(8):1124-1135.   Published online August 15, 1994
We analysed 58 patients who were admitted to the Department of Pediatrics, yonsei University College of Medicine due to infectious mononucleosis from January 1986 to August 1992. Of 58 patients who had responses to IgM to EBV viral capsid antigen and/or heterophil antibody, 35 patients had hapatitis. Of 35 hepatitis patients, group I consisted of 22 patients who had only...
Case Reports
A Case of Acute Tubular Necrosis Induced by paraquat (Gramoxon®) Intoxication
Young Guk Kim, Dong Gun Park, Kee Hwan You, Keun Haeng Cho, Young Sook Hong, Soon Kyum Kim
J Korean Pediatr Soc. 1994;37(8):1143-1148.   Published online August 15, 1994
Paraquat (1, 1'-dimethy1-4, 4'dipyridium chlorde: Gramoxon￠c) was first discovered in England in 1955. It has been widely distributed for use in Korea since 1970 as a pesticide and also often the cause of accidental intoxications. The authors would like to report the following case of paraquat intoxication in a 13 year old female child admitted via emergency room with complaints...
Three Cases of Apert Syndrome (Acrocephalosyndactyly)
Young Sil Ahn, Jong Won Lee, Jin Keon Bang, Doo Bong Lee
J Korean Pediatr Soc. 1994;37(8):1149-1155.   Published online August 15, 1994
Apert syndrome is an uncommon, congenital disorder characterised by malformation of the skull, most often acrocephaly or oxycephaly, in association with symmetrical syndactyly of both hands and feet. It is due to disturbance in the growth of bone and soft tissue affecting principally the head, the hands and the feet. The original description was presented by Troquart in 1886, and...
A Case of Phakomatosis Pigmentovascularis
Seung Mo Park, Kook In Park, Hye Jung Joo, Ran Namgung, Chul Lee, Dong Gwan Han, Soo Il Chun
J Korean Pediatr Soc. 1994;37(8):1156-1161.   Published online August 15, 1994
In 1947, Ota et al. First reported a case of phakomatosis pigmentovascularis and defined a subgroup of this disease having a congenital generalized hemangioma and pigmented lesions including anmongolian spot-like lesion, nevus pigmentosus and nevus of Ota. We experienced a case of phakomatosis pigmentovascularis type Iib in a 10-day old male baby, who since birth, had generalized nevus flammeus and...
One Case of Maffucco's Syndrome with Testicular Teratoma
Seung Mo Park, Duk Hi Kim, Ho Seong Kim
J Korean Pediatr Soc. 1994;37(8):1162-1168.   Published online August 15, 1994
Maffucci's syndrome is a very rare, congenital and non-hereditary mesodermal dysplasia manifested by multiple enchondromas and soft tissue hemangiomas. Since Maffucci had reported this syndrome in 1881, there have been more than 100 cases reported, and also there has been reported that Maffuddi's syndrome has various interstitial tumor. However there hasn't been any report about Maffucci's syndrome with testicular teratoma....
A Case of Currino Triad
S.S. Park, G.H. Lee, H.S. Kim, K.H. Kim, H.S. Lee, Y.S. Lee
J Korean Pediatr Soc. 1994;37(8):1169-1174.   Published online August 15, 1994
Currarino triad is a unique malformation complex of congenital caudal anormalies, including anorectal malformation (anal stenosis, anal ectopia, imperforated anus), sacral bony abnormality (scimitar or crescentic bony defect, malsegmentation) and presacral mass (meningocele, teratoma, enteric cyst or any combination of these). This triad is familial in at least half of cases and the usual symptomatology is constipation due to anorectal stenosis....
A Case of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) Positive Wegener's Granulomatosis
Won Tae Kim, Woo Jeong Kim, Joon Sik Kim, Chin Moon Kang, Kwan Kyu Park
J Korean Pediatr Soc. 1994;37(8):1175-1181.   Published online August 15, 1994
Wegener's granulomatosis is a disease of unknown etiology that is characterized by the clinicopathologic complex of necrotizing granulomatous vasculitis of the upper and lower respiratory tract, glomerulonephritis, and variable degrees of small vessel vasculitis. Recently Antineutrophil Cytoplasmic Antibody (ANCA) has been reported to be a highly specific test for the diagnosis of Wegener's granulomatosis. We have experienced a patient of Wegener's...