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Volume 50(8); Aug 2007
Review Articles
Physiology of sleep
Kyu Young Chae
Korean J Pediatr. 2007;50(8):711-717.   Published online August 15, 2007
Sleep is a vital, highly organized process regulated by complex systems of neuronal networks and neurotransmitters. Normal sleep comprises non-rapid eye movement (NREM) and REM periods that alternate through the night. Sleep usually begins in NREM and progresses through deeper NREM stages (2, 3, and 4 stages), but newborns enter REM sleep (active sleep) first before NREM (quiet sleep). A...
Sleep disorders in childhood
Byung Ho Cha
Korean J Pediatr. 2007;50(8):718-725.   Published online August 15, 2007
Sleep disorders are very common among pediatric patients. Its prevalence is between 10% and 45% in preschool- and school-aged children. However parents commonly do not concern about their children's sleeping habits and for many pediatricians, there is not part of the routine office visit about a childs sleep. Sleep disorders were classified by International Classification of Sleep Disorder (ICSD) as...
Non-epileptic paroxysmal events during sleep - Differentiation from epileptic seizures -
In Kyu Lee
Korean J Pediatr. 2007;50(8):726-731.   Published online August 15, 2007
This review describes the wide spectrum of paroxysmal events during sleep in infancy and childhood. The differential diagnosis between sleep-related non-epileptic paroxysmal events and epileptic seizures is difficult in special occasions. The nocturnal frontal lobe seizure and of the more common non- epileptic paroxysmal events during sleep are described. The main differentiating features characterizing parasomnias are: onset in early...
Original Articles
Birth weight for gestational age patterns by sex, plurality, and parity in Korean population
Jung Ju Lee
Korean J Pediatr. 2007;50(8):732-739.   Published online August 15, 2007
Purpose : A universal standard of the birth weight for gestational age cannot be made since birth weight distribution varies with races, nations and eras. This report aims to establish the birth weight for gestational age patterns by sex, plurality, and parity, specific for Korean live births. Methods : The national birth certificate data of all live births in Korea from...
Comparison of neonatal outcomes between the spontaneous and in vitro fertilization twin pregnancies
Hee Moon Kim, Jeong Won Lee, Seon Hee Shin, Sung Koo Kim, Tae Jung Sung
Korean J Pediatr. 2007;50(8):740-745.   Published online August 15, 2007
Purpose : There is a dominant opinion that in vitro fertilization (IVF) leads to an increased incidence of twins, low birth weight (LBW) infants, prematurity and mortality. On the other hand, technical development of IVF and improvement of neonatal intensive care have increased the survival rate of neonates. The purpose of this study was to verify the tendency by comparing...
Correlation of serum total hydroperoxide levels and diseases of prematurity
Shin-Hye Kim, Hae Young Hur, Kyu Hyoung Lee, Ja Young Moon, Kyu Young Chae
Korean J Pediatr. 2007;50(8):746-751.   Published online August 15, 2007
Purpose : Total hydroperoxide (TH), free radical-mediated oxidation product can be used as a measure of free radical injury. The aim of the present study was to see if preterm newborns are at increased risk for oxidative stress compared with term newborns, and to determine whether oxidative stress during postnatal first 1 week is associated with clinical outcomes in preterm...
Comparison of polyethylene glycol 4000 and lactulose for treatment of chronic functional constipation in children
Ji Hyun Uhm
Korean J Pediatr. 2007;50(8):752-756.   Published online August 15, 2007
Purpose : The aim of this study was to compare 2 laxatives, namely, polyethylene glycol 4000 without electrolytes and lactulose, evaluating the efficacy and safety for the treatment of constipation in children. Methods : Fifty-six children with chronic functional constipation were randomly assigned to receive polyethylene glycol 4000 (24 patients) or lactulose (32 patients). Patients or their parents reported defecation frequency,...
Unprovoked seizures in children with complex febrile convulsion; short-term outcome
Ji Yeon Choi, Eun Jung Cheon, Young Hyuk Lee
Korean J Pediatr. 2007;50(8):757-760.   Published online August 15, 2007
Purpose : Febrile convulsions (FC) were considered to be a benign seizure syndrome that is distinct from epilepsy. But it is thought that children with complex features i.e., partial or prolonged seizures or multiple episodes of FC would bear a higher risk of developing unprovoked seizures. The aim of this study is to look into the relative significance of each...
A study for post-diagnostic lumbar puncture headache in children
Gook Chan Jang, Eun Seok Yang, Kyung Rye Moon, Young Bong Park, Young Il Rho
Korean J Pediatr. 2007;50(8):761-766.   Published online August 15, 2007
Purpose : Post-lumbar puncture headache is common complaint. A study of post-diagnostic lumbar puncture headache in children is rare. Various factors that might influence the occurrence of post- diagnostic lumbar puncture headache in children exist. The purpose of this prospective study was to assess the frequency and risk factors for post-diagnostic lumbar puncture headache in children. Methods : From March 2005...
Alteration of insulin resistance and serum adiponectin levels after one year follow-up of obese children and adolescents
Min Jee Jeoung, Jung Yeon Shin, Soo Young Kim, Jung Hwa Lee, Kee-Hyoung Lee, Joo Won Lee
Korean J Pediatr. 2007;50(8):767-773.   Published online August 15, 2007
Purpose : Obesity has become a pandemic and especially the prevalence of childhood obesity has increased remarkably over the past years. Childhood obesity is often accompanied by the expected morbidities such as hyperlipidemia, fatty liver and glucose intolerance. We evaluated the pattern of alteration in the body mass index (BMI), serum adiponectin concentration, insulin resistance (HOMA-IR), and complication rates after...
Plasma B-type natriuretic peptide (BNP): a useful marker for anthracycline-induced cardiotoxicity in Korean children with cancer
Hyun Dong Lee, Jae Min Lee, Yong Jik Lee, Young Hwan Lee, Jeong Ok Hah
Korean J Pediatr. 2007;50(8):774-780.   Published online August 15, 2007
Purpose : The anthracyclines (AC) are widely used chemotherapeutic agents for pediatric cancers. However, the therapeutic use of these agents is limited by their cardiotoxicity. The aim of the present study was to investigate the usefulness of plasma B-type natriuretic peptide (BNP) levels as a marker for AC-induced cardiotoxicity compared to echocardiography in Korean children with cancer. Methods : Fifty-five pediatric...
Case Reports
Bronchial foreign body aspiration diagnosed with MDCT
Hye Kyung Cho, Ky Young Cho, Sung Yoon Cho, Sejung Sohn
Korean J Pediatr. 2007;50(8):781-784.   Published online August 15, 2007
Foreign body aspiration (FBA) is a common accident in young children. Undiagnosed and retained foreign bodies may result in severe early and late complications such as asphyxia, pneumonia, atelectasis and bronchiectasis. Moreover, because it can mimic bronchiolitis, croup or asthma, an accurate history and a high index of suspicion are of paramount importance for early diagnosis. With our experience on...
Epidural emphysema and pneumoscrotum caused by bronchial foreign body aspiration
Dong-Yeon Kim, Woo-Yeon Choi, Young-Kuk Cho, Jae-Sook Ma
Korean J Pediatr. 2007;50(8):785-788.   Published online August 15, 2007
Epidural emphysema and pneumoscrotum with subcutaneous emphysema are rare in a child past the neonatal period. Their most common causes are bronchial asthma and respiratory infection. Here, we report an 18-month-old boy who was presented with severe air leak, consisting of epidural emphysema, pneumoscrotum, subcutaneous emphysema, and pneumomediastinum, complicated by a bronchial foreign body. The air leak was resolved dramatically...
Basal cell nevus syndrome (gorlin syndrome) confirmed by PTCH mutations and deletions
Hee Moon Kim, Chul Hee Lee, Sung Koo Kim, Tae Jung Sung
Korean J Pediatr. 2007;50(8):789-793.   Published online August 15, 2007
Basal cell nevus syndrome (BCNS), also known as Gorlin syndrome, is a rare autosomal dominant disorder characterized by variable manifestations, including multiple basal cell carcinomas, odontogenic keratocysts of the jaw, skeletal anomalies including scoliosis and bifid ribs, palmar and plantar pits, calcification of the falx cerebri, and biparietal frontal bossing. We report a case of a 9-year-old boy with the...
A case of hepatopulmonary syndrome in a child with fatty liver disease secondary to hypopituitarism after craniopharyngioma resection
Sun Ju Im, Hyun Seok Park, Hyoung Doo Lee, Jae Hong Park, Hee Ju Park
Korean J Pediatr. 2007;50(8):794-798.   Published online August 15, 2007
Hepatopulmonary syndrome is a triad that includes: hepatic dysfunction, intrapulmonary vascular dilatation and abnormal arterial oxygenation. The incidence of intrapulmonary vascular dilatations, in adults with end-stage liver disease, has been reported to be 13% to 47%, however the incidence in children is unclear and the cases in Korean children have never been reported. The hepatopulmonary syndrome may occur as a...
Rotavirus Vaccine
Su Eun Park, Kyung Hyo Kim, Jong-Hyun Kim, Seon Hee Shin, Sung Hee Oh, Hoan Jong Lee, Dae Sun Jo, Eun Hwa Choi, Jae Kyun Hur, Young Jin Hong
Korean J Pediatr. 2007;50(8):803-810.   Published online August 15, 2007
Human Papillomavirus Vaccine
Kyung Hyo Kim, Jong-Hyun Kim, Su Eun Park, Seon Hee Shin, Sung Hee Oh, Hoan Jong Lee, Dae Sun Jo, Eun Hwa Choi, Jae Kyun Hur, Young Jin Hong
Korean J Pediatr. 2007;50(8):811-819.   Published online August 15, 2007