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Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11,14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87... |
Recently, the incidence of perinatal death in this country has decreased by improved antenatal care and resuscitative management, but is still higher than that of developed country. A number of studies on perinatal death have dealed with mainly statistical and clinical aspect. We studied about perinatal death in order to prove more accurate cause of death by autopsy. The subjects of our study were... |
Since the 1960s, several reports have been presented to explain how the ingestion of human milk is related to neonatal jaundice. Recently, the jaundiced neonates whose mother’s milk contain sub- stances (eg, pregnane 3a, 20β-diol, lipoprotein lipase, free fatty acid, β-glucuronidase etc) facilitating the reabsorption of unconjugated bilirubin in the neonatal intestine through the enhancement of the enterohepatic circulation, were called the breast milk... |
Enterotoxigenic Escherichia coli (ETEC) cause an acute cholera-like diarrhea in both human and animals. The disease process involves colonization of the mucosal surfaces of the small intestine followed by elaboration of ST and/or heat-labile enterotoxin (LT). Intestinal colonization by ETEC is mediated by specific surface-associated fimbrial or fibrillar antigens including colonization factor antigens (CFA) I and II. Isolates of E. coli from 114 children with... |
Measurement of blood pressure in neonate is an important diagnostic procedure. But measurement of blood pressure were not performed routinely because of difficulty in measuring blood pressure and variable normal range according to measuring apparatus. Recently some accurate and convinient apparatuses of measuring blood pressure have been introduced in neonatal care, so normal blood pressure values of neonate are needed. In this study, we establish... |
Pulmonary and aortic valvular stenosis were relieved by percutaneous balloon valvuloplasty during cardiac catheterization on 14 children aged 22 months to 18 years. Before dilatation the transpulmonary systolic pressure gradients ranged from 43 mmHg (mean 87. 8 mmHg) in children with pulmonary valvular stenosis. There were significant reduction in the transpulmonary systolic pressure gradient (mean 33.1 mmHg) immediately after balloon valvuloplas- ty except one patient... |
Thes is a study on changes of plasma renin activity (PRA) and aldosterone concentration (PAC) which was obtained before and after heart operation in 26 normotensive children with congenital heart diseases without renal disease admitted in Chungnam National University Hospital for cardiac catheterization with angiogram and heart operation from Apr. 1988 to Aug. 1988 to confirm any differences of PRA and PAC between groups... |
Kawasaki disease is an acute febrile illness of unknown origin and most frequently affects infants and children younger than age 5 years. Coronary aneurysms are most serious complication in Kawasai diseas and are developed in 15〜20% of patients. We studied 15 children Kawaski disease complicating coronary aneurysms, who were admitted to the Kyung Hee University Hospital during the period of January 1984 through January... |
To elucidate the characteristics of immunoregulatory system of children with chronic active hepatitis B and hepatitis B vaccine inoculated infant, the authors examined T cell subsets of the peripheral blood in 16 children with asymptomatic HBsAg carriers, 19 children with chronic hepatitis B (11 chronic persistent hepatitis (CPH) and 8 chronic active hepatitis (CAH) and 21 hepatitis B vaccine inoculated infants as well as... |
Methylprednisolone “pulse” therapy was performed on 22 patients of childhood nephropathies who showed resistance to conventional therapy. The diseases included steroid-resistant or frequent relaps- ing nephrotic syndrome including minimal change nephrotic syndrome, focal segmental glomer- ulosclerosis, membranous nephropathy, mesangioproliferative glomerulonephritis, Henoch-Schonlein purpura nephritis and SLE nephritis. Methylprednisolone 30 mg/kg/day was administered intravenously over one hour, which was repeated 6 times on every other day. Sixteen of... |
In this study, we attempted to determine an optimal first dose of phenobarbital for the treatment of seizures in the asphyxiated full term neonates. Blood samples were obtained 2 to 48 hours after the administration of final effective loading dose and plasma levels were determined by the EMIT system. Four groups of neonates were studied. Six neonates (Group 1) received an intravenous loading dose of... |
Fifty six boys and 28 girls aged 4 to 15.8 years were treated with oxandrolone during the 4 to 25 months. Measurement of height and bone age were made at the beginning and at 6 months intervals. The daily dose were 0.08 mg to 0.28 mg per kilogram. Predictions for adult height at the beginning of the study were compared with those at... |
The immunotherapy has become a useful and effective method to treat allergic respiratory diseases. It is a logical assumption that immunotherapy produces symptom relief as a result of immunologically specific response. This study was performed to delineate the IgE, IgG and IgG4 responses to immunotherapy, and their relationships. We selected the six asthmatic children on immunotherapy with Dermatophagoides pteronyssinus (Dp). A set of samples from each... |
We experienced a case of familial hypercholesterolemia in 9 year-old boy with hypercholester- olemia, tendon xanthoma, foamy histicoytes in skin biopsy and biochemical abnormalities in family members, but without abnoramlity of cardiovascular system. Diagnosis was established by clinical characteristics, serum chemistry and lipoprotein- electrophotesis. A brief review of related literatures was done. |
More recently, several studies have been repotted about the abnormalities of auditory brainstem response (ABR) in hyperbilirubinemia of newborn. By using of ABR, visual evoked potenital and nuclear magnetic resonance techniques, some investigators suggested that transient alteration in ABR in severely jaundiced neonates indicated reversible transient subclinical or clinical bilirubin induced neurotoxicity. They thought it would be the early stage of kernicterus. We experienced two... |
We experience 3 cases of Kawasaki disease accompanied with rare clinical manifestations. The first case was 6 year old boy who accompanied with hydrops of gallbladder and facial palsy. The second case was 7 month old boy who developed vesicles, crust, and desquamation of the BCG inoculation site. The third case was 18 month old boy who developed transverse groove (Bow’s line) of the... |
The narcoleptic syndrome consists of narcolepsy proper, cataplexy, sleep paralysis and hypnagogic hallucinations. The disease is not common in children. We experienced a case of narcolepsy in a 7-year old girl. Analeptic drugs are used for treatment. Diurnal attacks of sleep and concomitant muscular weakness were controlled with methylphenidate (ritalin hydrochloride) rather than caffeine, Historical literatures were also been reviewed, and several clinical aspects of... |
We have experienced a case of myelodysplastic syndrome (RAEB) in an 11-year-old boy with the complaints of pallor and petechiae for 1 month. After diagnosis, improvement was remarkable with chemotherapy of low dose cytosine arabinoside but the RAEB was transformed to acute myeloblastic leukemia 4 months after treatmemt. Anti-leukemic therapy was tried but induction of remission was failed and he was died of sepsis... |
The authors experienced a case of 45-day-old female newborn infant who showed the intractable tonic spasms with series formation and hypotonia. We diagnosed it through the evaluation of the clinical, radiological features including brain CT and electroencephalogram. The suppresion-burst pattern in EEG and clinical features aid to the confirmation of the diagnosis. A brief review of the related literature were made. |