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Volume 51(11); Nov 2008
Changes related term alteration of pediatrics and roles of pediatrician
Yong Kyu Sohn
Korean J Pediatr. 2008;51(11):1133-1135.   Published online November 15, 2008
The ultimate goal of the term alteration to pediatrics is that not only infants and children but also adlescents are subjet to pediatrics. At 27, June, 2007 the term pediatrics was altered to pediatrics (children and aoldescent medicine). From now on the roles of pediatricians for adolescents are needed and adolescent medicine should be reorganized in Korea. Although the numbers...
Review Articles
Urinary incontinence
Jung Won Lee
Korean J Pediatr. 2008;51(11):1136-1139.   Published online November 15, 2008
The genitourinary tract and gastrointestinal system are interdependent but share the same embryological origin, pelvic region, and sacral innervation. Although children with voiding disturbances often present with bowel dysfunction, this coexistence was considered coincidental until recently. However, it is now accepted that dysfunction in emptying of both systems is interrelated. Afferent impulses carrying sensory information are transmitted through the spinal...
Diagnosis and treatment of nocturnal enuresis in children
Chang Hee Hong, Minki Baek, Seong Ho Lee, Jeong Won Lee, Ki-Soo Pai
Korean J Pediatr. 2008;51(11):1140-1146.   Published online November 15, 2008
Nocturnal enuresis is a heterogeneous disorder with various underlying pathophysiological mechanisms and causes a mismatch between the nocturnal bladder capacity and the amount of urine produced during sleep at night. It is associated with a simultaneous failure of conscious arousal in response to the sensation of bladder fullness. Generally, a complete history and physical examination, with a specific focus on...
Diagnosis and therapy for functional urinary incontinence in childhood
Ju Hyung Kang
Korean J Pediatr. 2008;51(11):1147-1151.   Published online November 15, 2008
Functional urinary incontinence, the absence of any neurologic or structural abnormality as a cause of urinary incontinence in children, is one of the most common clinical problems encountered in pediatric and urologic departments, and it can be socially and emotionally distressing for the affected children. The prevalence rates of functional urinary incontinence in school-aged children are not very high and...
Original Articles
Analysis of online breast-feeding consultation on the website of the Korean Pediatric Society
Jung Yun Kim, Seoug Jae Hwang, Hyun Kyung Park, Ha-beck Lee, Nam Su Kim
Korean J Pediatr. 2008;51(11):1152-1157.   Published online November 15, 2008
Purpose : Since the infant formula milk has been produced in Korea, it has faced a low rate of breast milk feeding, though breast milk feeding is a little increasing. Therefore, the Korean Pediatric Society launched its website for breast-feeding consultation to provide information to the general public and enhance the health of growing infants. The consultation results were analyzed...
Performance effectiveness of pediatric index of mortality 2 (PIM2) and pediatricrisk of mortality III (PRISM III) in pediatric patients with intensive care in single institution: Retrospective study
Hui Seung Hwang, Na Young Lee, Seung Beom Han, Ga Young Kwak, Soo Young Lee, Seung Yun Chung, Jin Han Kang, Dae Chul Jeong
Korean J Pediatr. 2008;51(11):1158-1164.   Published online November 15, 2008
Purpose : To investigate the discriminative ability of pediatric index of mortality 2 (PIM2) and pediatric risk of mortality III (PRISM III) in predicting mortality in children admitted into the intensive care unit (ICU). Methods : We retrospectively analyzed variables of PIM2 and PRISM III based on medical records with children cared for in a single hospital ICU from January 2003...
Comparison of the seroconversion rate after primary hepatitis B vaccination and after revaccination of non-responders in full-term infants according to mother's HBsAg seropositivity
Jang Hee Kang, Jae Won Moon, Seung Hyun Kong, Kwang Su Hwang, Ji Sun Mok, Hyeon Jung Lee
Korean J Pediatr. 2008;51(11):1165-1171.   Published online November 15, 2008
Purpose : This study aimed to identify the true extent of non-responsiveness in full-term infants born from HBsAg-negative or HBsAg-positive mothers and vaccinated against hepatitis B virus (HBV) at 0, 1, and 6 months of age and to evaluate the effect of revaccination among non-responders. Methods : The study included 716 full-term infants born in 2004-2007. Of 716, 662 infants...
A clinical study of congenital chylothorax and octreotide therapy
Ung Geon Oh, Kyoung Eun Choi, Kyung Ah Kim, Sun Young Ko, Yeon Kyung Lee, Son Moon Shin
Korean J Pediatr. 2008;51(11):1172-1178.   Published online November 15, 2008
Purpose : Congenital chylothorax is an accumulation of lymphatic fluid within the pleural space. It is a common cause of unidentified hydrops fetalis. We examined the perinatal history, clinical manifestation, diagnosis, treatment, and outcome in 6 newborns diagnosed to have congenital chylothorax with hydrops fetalis. We also studied the effect of octreotide therapy for congenital chylothorax in relation to conservative...
Study of the risk factors for pulmonary interstitial emphysema related to mechanical ventilator care
Sang Yeob Kim, Pil Sang Lee, Sang Geel Lee
Korean J Pediatr. 2008;51(11):1179-1184.   Published online November 15, 2008
Purpose : Pulmonary interstitial emphysema (PIE) primarily occurs in preterm infants suffering from respiratory distress syndrome (RDS) and kept under mechanical ventilator care. Therefore, this study aimed to examine various risk factors for PIE, to identify conditions that can decrease the possibility of PIE development. Methods : PIE classification was conducted for 183 patients diagnosed to have RDS and receiving mechanical...
The immunogenicity and reactogenicity of Td booster vaccination in Korean preadolescents, aged with 11-12 years old
Soo Young Lee, Ga Young Kwak, Hye Rin Mok, Jong Hyun Kim, Jae Kyun Hur, Kyung Il Lee, Park Joon Su, Sang Hyuk Ma, Hwang Min Kim, Jin Han Kang
Korean J Pediatr. 2008;51(11):1185-1190.   Published online November 15, 2008
Purpose : This study was undertaken to evaluate the immunogenicity and reactogenicity of Td booster immunization in early preadolescents of Korea. Methods : Healthy preadolescents, who had been vaccinated with 4 or 5 doses of DTaP vaccines until 6 years old age, were enrolled in this study from August 2006 to April 2007. Diphtheria and tetanus anti-toxoid antibodies in sera were...
Clinical characteristics of Epstein-Barr virus infection detected by polymerase chain reaction in children less than 15 years old
Jong-In Na, Ok Lan Kim, Do-kyoung Seoung, Seong-Taek Yoo, Chang Woo Lee, Doo-Young Choi, Yeon-Kyun Oh, Ji-Hyun Cho, Jong-Duck Kim
Korean J Pediatr. 2008;51(11):1191-1197.   Published online November 15, 2008
Purpose : Previously, Epstein-Barr virus (EBV) infection was diagnosed by serological examination; currently, many EBV antigen detection methods have been developed and applied clinically for diagnosing EBV infection. To delineate the clinical characteristics of EBV infection, clinical and laboratory findings were evaluated for patients who tested positive in EBV polymerase chain reaction (PCR). Methods : EBV PCR was conducted in 352...
Analysis of disease mechanism of subacute necrotizing lymphadenitis in children
Hyun Jung Kim, Jung Suk Yeom, Ji Suk Park, Eun Sil Park, Ji Hyun Seo, Jae Young Lim, Chan Hoo Park, Hyang Ok Woo, Jae Min Cho, Jeong Hee Lee, Hee Shang Youn
Korean J Pediatr. 2008;51(11):1198-1204.   Published online November 15, 2008
Purpose : The cause of subacute necrotizing lymphadenitis, a rare disease in children, has not been completely clarified. This study was aimed to investigate the disease mechanism by examining clinical, radiologic, and immunohistochemical findings in children diagnosed with subacute necrotizing lymphadenitis after an excisional biopsy. Methods : We examined 19 lymph node tissue specimens from 17 children diagnosed with subacute...
The significance of corpus callosal size in the estimation of neurologically abnormal infants
Seung Taek Yu, Chang Woo Lee
Korean J Pediatr. 2008;51(11):1205-1210.   Published online November 15, 2008
Purpose : The development of the corpus callosum occupies the entire period of cerebral formation. The myelination pattern on magnetic resonance imaging (MRI) is very useful to evaluate neurologic development and to predict neurologic outcome in high risk infants. The thickness of the corpus callosum is believed to depend on the myelination process. It is possible to calculate the length...
Diamond-Blackfan anemia: long-term follow-up of six cases
Young Jun Son, Hee Jo Baek, Hoon Kook
Korean J Pediatr. 2008;51(11):1211-1216.   Published online November 15, 2008
Purpose : Diamond-Blackfan anemia (DBA) is a rare heterogeneous genetic disorder of infancy and early childhood. It is characterized by red cell aplasia, congenital anomalies, and a predisposition to cancer. Corticosteroids and red cell transfusions are the mainstays of therapy. We describe our experience of 6 cases of DBA that were encountered over a period of 16 years. Methods :...
Prevalence and clinical significance of the positive antinuclear antibody in children with idiopathic thrombocytopenic purpura
So Eun Jun, Seong Sik Park, Young Tak Lim
Korean J Pediatr. 2008;51(11):1217-1221.   Published online November 15, 2008
Purpose : An association between idiopathic thrombocytopenic purpura (ITP) and systemic lupus erythematosus (SLE) has been recognized for decades because thrombocytopenia is the first manifestation in some patients with SLE. However, the risk of later development of SLE in childhood ITP is currently unknown. We retrospectively evaluated the incidence and clinical significance of the positive antinuclear antibody (ANA) in children...
Case Reports
A case of restless legs syndrome in a child presenting with growing pains
Dong Soon Kim, Hong Beom Shin, Young Min Ahn
Korean J Pediatr. 2008;51(11):1222-1227.   Published online November 15, 2008
Restless legs syndrome (RLS) is a common neurological sleep disorder in adults characterized by the following diagnostic criteria: an urge to move that is usually associated with unpleasant sensations and symptoms that are worse at rest, relieved by movement, and most severe at night. The definite diagnosis of RLS in children is stricter and consists of self-description of leg discomfort...
A case of vancomycin-induced drug hypersensitivity syndrome
Kyung Sun Min, Woo Yeon Choi, Eun Song Song, Dong Kyun Han, Young Kuk Cho, Jae Sook Ma
Korean J Pediatr. 2008;51(11):1228-1231.   Published online November 15, 2008
Drug hypersensitivity syndrome (DHS) has rarely been reported in association with vancomycin treatment. Here, we describe an 11-year-old girl who developed fever and a maculopapular rash on day 18 of intravenous vancomycin for treatment of infective endocarditis. The patient presented with fever, a maculopapular skin rash, hepatitis, and acute renal failure caused by vancomycin-induced DHS. The symptoms resolved in less...
A case of imipramine induced toxicity with Brugada electrocardiographic pattern in a toddler
Woo-Yeon Choi, Soo-Min Park, Ui-Jeong Han, Young-Nam Kim, Young-Kuk Cho, Jae-Sook Ma
Korean J Pediatr. 2008;51(11):1232-1235.   Published online November 15, 2008
Imipramine, a tricyclic antidepressant (TCA), is used for the treatment of non-polar depression and nocturnal enuresis in children in whom an organic pathology has been excluded, anxiety disorders, and neuropathic pain. Clinical toxicity following the treatment of TCAs, including imipramine, is well known. The anticholinergic effects initially present include a dry mouth, ileus, dilated pupils, urinary retention, and mild sinus...
A case of Smith-Lemli-Opitz syndrome diagnosed by identification of mutations in the 7-dehydrocholesterol reductase (DHCR7) gene
Mee Rim Park, Jung Min Ko, Chong-Keun Cheon, Gu-Hwan Kim, Han-Wook Yoo
Korean J Pediatr. 2008;51(11):1236-1240.   Published online November 15, 2008
Smith-Lemli-Opitz syndrome (SLOS) is a rare, autosomal recessive disease caused by an inborn error in cholesterol synthesis. Patients with this disease suffer from multiple malformations due to reduced activity of 7-dehydrocholesterol reductase (DHCR7), which increases 7-dehydrocholesterol (7DHC) and 8-dehydrocholesterol (8DHC) concentrations and decreases cholesterol concentration in body fluids and tissue. The SLOS phenotypic spectrum ranges from a mild disorder with...
The clinical phenotype of the derivative (8)t(7;8)(q22;p23.3) in two siblings
Young Ok Kim, Young Kuk Cho, En Song Song, Dong Kyun Han, Ic Sun Choi, Hee Jo Baek, Chan Jong Kim, Young Jong Woo, Young Youn Choi
Korean J Pediatr. 2008;51(11):1241-1244.   Published online November 15, 2008
We report on 2 siblings with a partial trisomy of 7q (7q22→qter) and concomitant partial monosomy of 8p (8p23.3→pter), which were shown by FISH using probes located at the telomere region of each chromosome. All the balanced translocation carriers (father and a sister) in this family had a normal phenotype. The 2 siblings with the same abnormal karyotype had similar...
Kim Ki-Ho: Comment on tuberculosis chemotherapy and its theoretical backgrounds (1), (II). (Soakwa 1959;3:171-4)
Korean J Pediatr. 2008;51(11):1245-1246.   Published online November 15, 2008
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