Purpose : This study was designed to clarify the mechanism of proteinuria in nephrotic syndrome patients by using puromycin aminonucleoside (PAN) nephrosis model. Methods : Following administration of various concentrations of PAN and antioxidants we observed the changes of podocyte cytoskeletons in cultured rat glomerular epithelial cells (GEpC) by method of scanning electron microscope, reactive oxyten species (ROS) analysis, permeability assay,... |
Purpose : Although suprapubic bladder aspiration(SBA) is the most reliable technique for identifying bacteriuria in young infant, no report has been published about the clinical manifestations of urinary tract infection(UTI) diagnosed by aspirated urine in Korea. This study was performed to examine clinical manifestations and related factors of UTI confirmed by a positive urine culture obtained by SBA in young infants. Methods : We reviewed... |
Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly... |
Purpose : We investigated the menstrual features of adolescent school girls to know the characteristics of menarche and dysfunctional uterine bleeding in adolescents. Methods : In March, 2001, 1,434 primary and middle school girls(10-15 years of age) in Ansan City were investigated for the menacheal age and several aspects of menstruation through questionnaire. Results : Mean age of the total subjects were... |
Purpose : Risk-taking behaviors are defined as patterns of behavior initiated during adolescence which are responsible for the majority of negative health outcomes occurring during the rest of the life. The study was to explore the relationship between the risk-taking behaviors and their predisposing factors among adolescents. Methods : The study used a survey design with an anonymous self-report questionnaire administered to 1,076 students from... |
We experienced a case of measles encephalopathy with thalamic lesion on magnetic resonance imaging(MRI) in a 12 year old boy. Measles symptoms such as fever, erythematous maculopapular rashes on whole body and cough with sputum appeared 4 days before neurologic signs such as agitation and drowsy-to-confused mentality. He showed remarkable motor dysfunction without evidence of sensory loss. MRI showed bilateral... |
Trisomy 9p syndrome was first described by Rethore et al in 1970 and about 100 cases have been reported since. The phenotypic spectrum of this syndrome is characterized by craniofacial malformation, facial deformity, skeletal and dermatoglyphic anomalies with variable degrees of mental retardation. We experienced a case of partial trisomy 9 syndrome in a 15-month-old female who had multiple congenital... |
Tubo-ovarian abscess is an end-stage disease of acute pelvic inflammatory disease(PID). Since most cases of PID are caused by sexually transmitted microorganisms, this is very rare in children. Here, we report an 1¨o-year-old girl with bilateral tubo-ovarian abscesses. She was admitted to our department with chief complaints of fever, vomiting and diarrhea. Abdominal ultrasonography and CT scanning of the patient... |
Purpose : Most studies of depression in adolescents, have been conducted in western countries. Accordingly, we took a survey in the city of Ansan to discover the actual state of depression in adolescents and found a solution. Methods : Twelve questions of modified diagnostic criteria for DSM-Ⅳ(Diagonstic and Statistical Mannual of Mental Disorders, 4th ed.) major depressive disorder were filled out... |
Purpose : Menstrual disorders are very common problems in adolescence. Most of them are minor, including mild dysmenorrhea, premenstrual syndrome(PMS) and minor variations in cycle, length, or amount of flow. Dysmenorrhea is the most prevalent among them while PMS is a nebulous condition characterized by a broad spectrum of symptoms. The purpose of this study is to investigate the correlation... |
Transient neonatal pustular melanosis(TNPM) is a benign, self-limited, cutaneous disorder of unknown etiology. Significant physical findings are limited to the skin. Hematologic and serological tests are normal. Cultures of blood and pustule are negative. Biopsy specimens from pustules show a intracorneal or subcorneal separation containing neutrophils and also some eosinophils. TNPM produces only cutaneous lesions and requires no treatment. So... |
Purpose : Routine liver function test follow up is done in epileptic children receiving antiepileptic drugs to prevent hepatotoxicity induced by these drugs. But rarely seen are the abnormalities of liver function test, and seldomly are these abnormalities accompanied by the clinical manifestation. This study is carried out to assess the efficacy of routine liver function test follow up in... |
Purpose : There have been controversies on the hematologic effects of antiepileptic drugs according to the mono or combined antiepileptic therapy. We evaluated the hematologic changes of the patients who have been taking antiepileptic drugs for more than 4 months and compared the changes of these values according to the mono or combined therapy. Methods : From May,1989 to April,1995, we had examined the blood... |
Purpose : Menstruation is a great part as the procedure for physiological, psychological development and physical growth, and menstrual disorders are very common problems in adolescence period. These problems can be resolved by interview or appropriate education of normal pubertal development. However unlike other developed countries, systematic report or appropriate education for menstruation may not be performed in our country.... |
Agenesis of the lung is a developmental defect with complete absence or profound hypoplasia of one or both lung : absence of one lung is more common. Absence of both lung is very rare and is incompatible with life. Unilateral or bilateral agenesis of the lung often associated with the skeletal, cardiovascular, gastrointestinal and genitourinary anomalies. H-type tracheoesophageal fistula in... |
Cleidocranial dysostosis is a rare, inherited abnormality which affects the development of mem- bransous and cartilaginous bone. Authors report a case of cleidocranial dysostosis with leukemia in a 10 year old boy. The review of the literature was made briefly. |
Neuroblastoma is one of the most common malignancy in infancy & childhood, but congenital neuroblastoma is rare. We experienced a case of congenital neuroblastoma of right posterior mediastinum without metastasis in 10-day-old female neonate. The diagnosis was established by autopsy including gross and microscopic finding. A brief review of literatures was made. |
The author determined mycoplasma antibody titer in 216 cases of pneumonia who were admitted to the pediatric ward of Korea Medical Center Guro Hospital from November, 1985 to September, 1986, and clinical investigation and statistical analysis were performed between mycoplasma anti- body positive group and negative group. The following results were obtained: 1) In 216 cases of children with pneumonia, incidence of mycoplasma antibody positive cases... |