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Original Article
Quantification of endothelin-1 in human umbilical venous endothelial cell culture supernatants of small for gestational age and preeclampsia neonates
Won Kyoung Cho, So Young Kim, Chung Sik Chun
Clin Exp Pediatr. 2007;50(12):1194-1199.   Published online December 15, 2007
Purpose : It was generally accepted now a days that the pathogenesis of preeclampsia, small for gestational age (SGA), intrauterine growth retardation and fetal origin of adult diseases were related with a endothelial cell dysfunction. The purpose of this study was to know the relation of such diseases by assessing the level of endothelin-1. Methods : SGA babies, newborns of...
Effects of Insulin-like Growth Factor-I and 1,25-(OH)2 Vitamin D3 Concentration on Intrauterine Growth of Newborns from Mothers with Preeclampsia
In Sook Yang, Jung Hyun Lee, Hyung Shin Lee, So Young Kim, Sung Dong Choi, In Kyung Sung, Chung Sik Chun
Clin Exp Pediatr. 2004;47(5):527-531.   Published online May 15, 2004
Purpose : This study was undertaken to observe the blood levels of IGF-I and 1,25-(OH)2 Vit. D3 in maternal and neonatal compartments and the effects of IGF-I concentration on intrauterine fetal growth and 1,25-(OH)2 Vit. D3 metabolism in the presence of preeclampsia. Methods : Thirty-four full-term pregnant women with preeclampsia and their newborns(preeclampsia group) and 10 normotensive full-term pregnant women and...
Plasma L-Arginine Concentration, Oxygenation Index and Pulmonary Artery Pressure in Premature Infants with Respiratory Distress Syndrome
Kyong Ah Jeong, Soon Ju Lee, In Kyung Sung, Chung Sik Chun
Clin Exp Pediatr. 2003;46(12):1207-1211.   Published online December 15, 2003
Purpose : This study was performed to observe the relationship of plasma L-arginine level and the severity of disease and pulmonary artery pressure in respiratory distress syndrome of premature infants. Methods : Peripheral blood samples were obtained at 1st, 3rd and 7th day from 21 premature infants with respiratory distress syndrome to analyze the L-arginine concentration. Oxygenation index (OI), an indicator...
Case Report
Two Cases of Hydrometrocolpos in Neonate
Min Young Park, Bo Ra Son, So Young Kim, Young You Kim, Hyun Hee Kim, Won-Bae Lee, In Kyung Sung, Chung Sik Chun, Su Aa Lim
Clin Exp Pediatr. 2002;45(2):278-283.   Published online February 15, 2002
Imperforated hymen, vaginal atresia or high transverse vaginal septum are caused by incomplete vaginal canalization. The infant may be present with distention of the vagina and the uterus with glandular secretions stimulated by maternal estrogens, known as hydrometrocolpos. We report two cases of hydrometrocolpos. In the first case, distal vaginal atresia with cystovaginal fistula was revealed by a contrast fluoroscope...
Original Article
The Effect of the Maternal Hypertension on the Lipid Peroxidation and Antioxidant Status in the Newborn Rat Lung
You Jin Jung, So-Young Kim, In Kyung Sung, Chung Sik Chun
Clin Exp Pediatr. 2001;44(5):545-551.   Published online May 15, 2001
Purpose : The aim of this study was to investigate the effect of the maternal hypertension on the lipid peroxidation and antioxidant status of the newborn rat lung. Methods : We used adult female SHR(essential hypertension, 1b, A, 6-8 weeks), Sprague-Dawley white rats as a model of hypertensive dams. Breeding was accomplished by allowing female and male rats to cohabit overnight....
The Effect of Erythromycin on Gastric Antrum and Low Esophageal Sphincter in the Newborn Rabbit
Sung Dong Choi, Chung Sik Chun
Clin Exp Pediatr. 2000;43(1):34-42.   Published online January 15, 2000
Purpose : We studied smooth muscle strips from rabbit gastric antrum and low esophageal sphincter(LES) to explore the difference between newborn and adult rabbit on erythromycin(EM)- induced contractions. Another aim of this study was to determine the mechanism of LES contractile activities induced by erythromycin(EM). Methods : Muscle strips prepared from newborn and adult rabbits were stimulated with agonists such as KCl, motilin and EM,...
Report of Nationwide Epidemiology of Aseptic Meningitis Outbreak in 1993 in Korea
Sung Hee Oh, Moo-Song Lee, Jin Han Kang, Chang Hwi Kim, Chong Young Park, Young Mo Sohn, Hoan Jong Lee, Chung Sik Chun, Sang Mann Shin
Clin Exp Pediatr. 1996;39(1):42-52.   Published online January 15, 1996
Purpose : There has been no nationwide report pertaining to the epidemiology of aseptic meningitis, although a great numer of patients have been diagnosed of the illness. Therefore, we report an explosive outbreak of aseptic meningitis occured in a nationwide scale in 1993. Methods : Aseptic meningitis epidemiology surveillence was performed retrospectively on the patients diagnosed of aseptic meinigitis from January...
A Case of Dandy-Walker Syndrome Associated with Multiple Congenital Anomalies.
Gye Weon Shin, Chul Ho Lee, Bo Kyung Cho, Chung Sik Chun, Sung Hun Cho
Clin Exp Pediatr. 1990;33(6):848-853.   Published online June 30, 1990
The Dandy-Walker Syndrome is a developmental disorders of the brain characterized by cystic deformity of fourth ventricle, agenesis or hypoplasia of the cerebellar vermis, and hydrocephalus. This syndrome is frequently associated with central nervous system malformation and systemic anomalies. We experienced a case in a 2-day-old female who has multiple congenital anomalies. On physical examinations, macrocephaly with prominent occiput, encephalocele in the occipital area, microphth- almia,...
A case of bronchopulmonary dysplasia.
Sun A Chun, Byung Jun Choi, Bo Kyung Cho, Chung Sik Chun, Sung Hoon Cho
Clin Exp Pediatr. 1989;32(11):1553-1559.   Published online November 30, 1989
The development of respiratory management of the newborn has improved the survival rates of respiratory distress syndrome in these two decades. But the incidence of complication associated with this management has been increased. Although the pathogenesis of bronchopulmonary dysplasia has not been clearly established yet, bronchopulmonary dysplasia is one of the major complication of the mechanical ventilation. There are several factors in the development of...
Clinical Observation on 29 Cases of Congenital Syphilis.
Kyung Ae Kim, Kyung Hee Han, Chung Sik Chun, Chang Kyn Oh, Mahn Kyn Yang
Clin Exp Pediatr. 1982;25(8):824-828.   Published online August 31, 1982
Authors made clinical observation on 29 cases of congenital syphilis, who were born from 54 cases of syphilitic mothers, at the St. Paul's Hospital from Jan. 1976 to Dec. 1980. The results were as follows. 1. The incidence of syphilis among the admitted pregnant women for delivery was 0.9%. 2. The incidence of neontal syphilis from the 54 syphilitic mothers...
Case Report
A Case of Patent Urachus.
Jong Wan Kim, Hack Ki Kim, Chung Sik Chun, Chang Kyu Oh, Mahn Kyoo Yang
Clin Exp Pediatr. 1982;25(3):295-299.   Published online March 31, 1982
Pateat urachus is a uncommon disease and it has a good prognosis if there is no combired major anomaly and evidence of malignancy. This paper presents one case of patent urachus which was found and removed surgically during the neonatal period. A brief review of related literatures is also presented.
A case of Aplastic Anemia following Hepatitis.
Yong Eun Chung, In Kyung Sung, Chung Sik Chun, Chang Kyu Oh, Mahn Kyoo Yang
Clin Exp Pediatr. 1980;23(8):670-673.   Published online August 15, 1980
Aplastic anemia following hepatitis is uncommon disease and it has a poor prognosis. Recently authors expirienced a case of aplastic anemia following hepatitis in 13-year-old boy. He was admitted due to jaundice and ecchymosis for 1 month. During admission, pancytopenia developed and there was marked hypocellularity of all elements in bone marrow examination. His clinical course was not improved in...
A Case of Sclerosing Cholangitis
Chung Sik Chun, Soon Ja Kim, Soo Woong Lee
Clin Exp Pediatr. 1976;19(10):717-721.   Published online October 31, 1976
Sclerosing cholangitis is a rare condition of unknown etiology, presenting extrahepatic biliary obstruction due to a chronic inflammatory obliterative process. Criteria for diagnosis include progressive biliary obstruction due to chronic inflammatory fibrous process, absence of biliary stones, absence of biliary surgery prior to onset of symptoms, and a follow up period long enough to exclude sclerosing carcinoma of the biliary...
One Case of Crossed Renal Ectopia with Fusion
Jae Wook Kim, Chung Sik Chun, Hyo Kun Moon
Clin Exp Pediatr. 1976;19(1):57-59.   Published online January 31, 1976
Crossed renal ectopia is a relatively rare congenital anomaly. This condition is characterized by fusion of one organ across the midline with its renal mate. The normal initial bilateral embryologic development occurs, but early in renal ascent one organ crossed the midline and fuses with its mate or lies adjacent. Crossed renal ectopia is said to occur about once in...
Case Report
Paroxysmal Atrial Tachycardia in Child
Chung Sik Chun, Eul Kyung Kim, Kyong Su Lee, Chui Hee Lee
Clin Exp Pediatr. 1975;18(7):523-526.   Published online July 31, 1975
They say that paroxysmal atrial tachycardia is not common in childhood. One case of paroxysmal atrial tachycardia combining with congestive heart failure in 9 months old male infant which had been experienced was presented and reviewed briefly. He was admitted to the Holy Family Hospital with the complaints of irritability, breaths heavily and puffy face. On physical examination, chest X-ray and...