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Original Article
Renal manifestations in tuberous sclerosis complex
Il Cheon Jeong, Ji Tae Kim, You Sik Hwang, Jung A Kim, Jae Seung Lee
Clin Exp Pediatr. 2007;50(2):178-181.   Published online February 15, 2007
Purpose : The renal manifestations of tuberous sclerosis complex (TSC) are remarkably diverse, including polycystic kidney disease, simple renal cysts, renal cell carcinomas, and angiomyolipomas. All of these occur in children as well as adults in TSC. Angiomyolipomas, which can cause spontaneous life-threatening hemorrhages, are by far the most prevalent and the greatest source of morbidity. Here, we will address...
A clinical study of systemic lupus erythematosus in children
Ji Tae Kim, Young Mee Nam, Jae Seung Lee, Dong Soo Kim
Clin Exp Pediatr. 2007;50(1):74-78.   Published online January 15, 2007
Purpose : Systemic lupus erythematosus (SLE) is a chronic multisystemic autoimmune disease with complex clinical manifestations. It probably involves genetic, environmental and immunologic factors. In this study, we investigated the clinical manifestations, laboratory findings and prognosis of pediatric SLE to aid clinical care of pediatric SLE. Methods : The data of 45 patients who were diagnosed as pediatric SLE in Severance...
Pharmacokinetics of Cyclosporine A and Its Therapeutic Effect in Children with Renal Diseases
Woo Sung Chun, Min-Soo Park, Jae Seung Lee, Juyun Yu, Moon Sung Park, Ki-Soo Pa
Clin Exp Pediatr. 2004;47(2):193-203.   Published online February 15, 2004
Purpose : To know the body handling properties and anti-proteinuric effect of cyclosporine A(CsA) in children with renal diseases, 34 patients with nephrotic syndrome or glomerular diseases were included to treatment trials and evaluated. Methods : Microemulsion formula CsA, 5 mg/kg/day was administered orally in two divided doses for 9.3?.6 months. Pharmacokinetic studies of CsA were done twice at beginning and...
Case Report
A Case of Congenital Megacystis Due to Non-Obstructive Urinary Retention Associated with Intestinal Malrotation and Hypoperistalsis
Tai Young Ham, Jeong Hoon Kim, Ji Hong Kim, Jae Seung Lee, Seok Ju Han, Choon Sik Yoon, Soon Won Hong
Clin Exp Pediatr. 2004;47(1):95-99.   Published online January 15, 2004
Congenital megacystis with bilateral hydroureteronephrosis is most commonly associated with posterior urethral valves, prune-belly syndrome, vesicoureteral reflux, or nonrefluxing, nonobstructive megaureters. Among the other cause of congenital megacystis, megacystis-microcolon-intestinal hypoperistalsis syndrome(MMIHS), which is characterized by megacystis, microcolon and hypoperistalsis of the intestines with resultant abdominal distension, is a rare cause of functional obstruction of urinary tracts in childhood. It was...
A Case of Incomplete Drash Syndrom
Im Jae Park, Hyunee Yim, Jae Seung Lee, Hyeon Joo Jeong, Woo Hee Jung
Clin Exp Pediatr. 1994;37(6):872-879.   Published online June 15, 1994
Drash syndrome, which was first reported by Denys et al. In 1967 is a complex disorder which associates a nephropathy, Wilms?tumor, and male pseudohermaphroditism. The common denominator is a nephropathey. The nephropathy may be associated with either genital abnormalities or Wilms?tumor, and these associations are called incomplete form of Drash syndrome. This syndrome appears early in life and the first...
A Case of Pararenal Pseudocyst and Congenital Hydronephrosis with Pisterior Urethral Valve
Jeong Lim Kim, Seung Yul Lee, Joon Soo Lee, Ki Soo Pai, Jae Seung Lee, Seung Kang Choi, Jin Suck Suh
Clin Exp Pediatr. 1992;35(2):263-268.   Published online February 15, 1992
Pararenal pseudocyst is an encapsulated cystic collection of chronically extravasated urine or serous fluid, usually occurring in the perirenal space by renal trauma, operative procedures or obstructive uropathy such as posterior urethral valve, or calculi, tumors of genitourinary tract and often associated with hydronephrosis and displacement of the kidney. We experienced a case of pararenal pseudocyst, right and congenital hydronephrosis, left...
Original Article
Mannitol induced acute oliguric renal failure.
Young Mi Chung, Jae Seung Lee, Chang Jun Coe
Clin Exp Pediatr. 1991;34(6):857-862.   Published online June 30, 1991
Mannitol known as non-electrolytic, osmotic diuretic agent is widely used in clinic for the purpose of diagnosis and prevention of acute oliguric renal failure, cerebral edema as well as glaucoma and dialysis-disequilibrium syndrome. That mannitol may cause serious life-threatening situation if administered in a patient with renal problem has been well known. Recently, it has been published that mannitol may be nephrotoxic in patient...
A Study on Pratol(R) Poisoning in Childhood.
Hyon Sook Seo, Heock Il Kwon, Jae Seung Lee
Clin Exp Pediatr. 1990;33(3):299-305.   Published online March 31, 1990
A Clinical observation was made on 22 cases of Pratol poisoning in childhood, who were admitted to department of pediatrics, severance hospital from January, 1979 to June, 1989. The results were as follows: 1) The ratio of male to female was 1:1 in total, 7 cases: 3 cases in the age group of 1 to 3 year and 3 cases: 7 cases in the age...
Five Cases of Horseshoe Kidney.
Yong Sil Chi, Pyung Kil Kim, Jae Seung Lee
Clin Exp Pediatr. 1988;31(2):276-281.   Published online February 28, 1988
Horseshoe kidney is the most common type of fusion anomaly during renal development. We report 5 cases of horseshoe kidney who were diagnosed at the pediatric department of Yonsei Medical Center, from February 1971 to December 1986. The summary of the study is as follows; 1) The age were variable from 1 day to seventeen years, 3 boys and 2 girls were affected. 2) As for the...
6 Cases of Renal Transplantation in Children.
Pyung Kil Kim, Fan Chen Mong, Jae Seung Lee, Kill Park, Dae Seuk Han
Clin Exp Pediatr. 1987;30(12):1419-1432.   Published online December 31, 1987
The incidence of end stage renal disease (ESRD) in childhood seems to be around two to three children per million population per year and the most frequent diagnoses of ESRD in pre-teen patients are congenital and dysplastic diseases. Renal transplantation may be the preferred method for the treatment of ESRD especially in children not only becauses of better development and linear growth, but also...
Complication of Percutaneous Renal Biopsy in Children.
Seo Jeong Kim, Jae Seung Lee, Pyung Kil Kim
Clin Exp Pediatr. 1987;30(9):1001-1013.   Published online September 30, 1987
Percutaneous renal biopsy is presently used more widely and selectively with fewer complications and a higher success rate than in the past. The improved methods of renal biopsy tissue handling and staining and the correlation of light microscopy results with those of electron and immunofluorescent microscopy have led to a quantum increase in our knowledge of renal diseases and have given great impetus to...
A Case of Bartter's Syndrome.
Jeong A Hwang, Jung Hye Choi, Jae Seung Lee
Clin Exp Pediatr. 1987;30(8):922-927.   Published online August 31, 1987
Bartter’s syndrome is rare disease which is characterized by hypokalemia, hypochloremic meta- bolic alkalosis, hyperreninemic hyperaldosteronism, hyporesponsiveness to pressors, and juxtag- lomeurlar apparatus hyperplasia. We had experienced a case of Bartter’s syndrome in 4 months old male infant. The diagnosis was made by clinical, biochemical and pathological studies. Literatures were reviewed briefly.
Case Report
A Case of Renal Candidiasis Associated with Type I Diabetes Mellitus.
Shin Heh Kang, Jae Seung Lee, Duk Hi Kim
Clin Exp Pediatr. 1987;30(6):677-683.   Published online June 30, 1987
We have experienced a case of renal candidiasis in type I DM (IDDM). The patient was a 15-year old girl who suffered from type I DM since 3 years earlier with development of retinopathy, cataract & renal failure. Ultrasonic examination revealed multiple fungus balls in renal pelvis & urinary bladder. Candida tropicalis was cultured from fungus balls passed during urination. A brief...
Original Article
Chronic Renal Failure in Children.
Yong Choi, Jong Duck Kim, Kwang Wook Ko, Jae Seung Lee, Pyung Kil Kim, Ja Hoon Koo
Clin Exp Pediatr. 1986;29(5):493-497.   Published online May 31, 1986
We analyzed data on children with chronic renal failure collected from 36 pediatric training hospitals during the period from Jan. 1, 1980 to Dec. 31, 1984. The following results were obtained： 1) Total number of children with chronic renal failure during the study period was 135. The incidence was about 1 per 2,000 in-patients and 2.09 per million children under 15...
A Clinical Study of Ureteral Duplication : Review of 90 Cases.
Jun Chul Choi, Jae Seung Lee, Ho Yung Lee, Dae Suk Han, Hyung Ki Choi, Jin Moo Lee, Jin Suck Suh
Clin Exp Pediatr. 1986;29(2):170-177.   Published online February 28, 1986
Ureteral duplication is one of the most common congenital malformations of the urinary tract. Incomplete duplication rarely causes clinical problems, but complete duplication often accompanies complications of a varying degree. We herein analyzed, retrospectively, 90 cases with ureteral duplication who were admitted to Yonsei University Severance Hospital during 13.5 years. There were 28 cases under age of 15 years. Thirty-four cases...
Study on Clinical Findings and Histopathologic Types in Biopsy Proven Glomerular Diseases in Korean Children.
Jae Seung Lee, Young Cherl Lee, Pyung Kil Kim, Hyeon Joo Jeong, In Joon Choi
Clin Exp Pediatr. 1986;29(2):143-151.   Published online February 28, 1986
A clinical and pathologic study was made on 360 cases of renal biopsies in children who were admitted to Severance Hospital, Yonsei University College of Medicine, from Jan. 1979 to Dec. 1984. 1) Among 360 cases, 250 cases were male and 110 cases were female. The sex ratio of male and female was 2.3 : 1. The distribution was from 1 6/12...
Clinical Study of 20 Pediatric Cases of HBs Antigenemia Associated Membranous Nephropathy.
Jae Seung Lee, Jung Hye Choi, Young Cherl Lee, Duk Jin Yun
Clin Exp Pediatr. 1984;27(8):760-765.   Published online August 31, 1984
A clinical study was done in 20 cases of HBs antigenemia associated membranous nephropathy admitted to the Department of Pediatrics, Yonsei University, College of Medicine, Severance hospital from Jan. 1979 to May 1984. The results are as follows; 1)The age distribution was from 2 years and 5 months to 14 years, and the mean age was 7 years and 10...
Case Report
A Case of Acute(infantile) Gaucher's Disease.
Baek Keun Lim, Kwan Sub Chung, Jae Seung Lee, Kir Young Kim, Byung Soo Kim, Duk Jin Yun, Chang Jin Kim, Chan Il Park
Clin Exp Pediatr. 1981;24(10):982-990.   Published online October 15, 1981
A case of Acute infantile form of Gaucher's disease in Korean infant is described. The large cells characteristically found in the bone marrow and liver in Gaucher's disease have been investigated with electron microscope, as well as light microscope. The pertinent literature has reviewed briefly concerning the clinical and laboratory fingings, roentgenographic picture, pathogenesis, pathology, diagnosis and treatment of this...
Original Article
Diagnostic Value of Serum Immunoglobulins in Glomerulonephritis.
Pyung Kil Kim, Kyo Sun Kim, Chul Lee, Nan Ae Kim, Jae Seung Lee
Clin Exp Pediatr. 1981;24(7):652-658.   Published online July 15, 1981
Serum immunoglobulin concenatrations were measured in 156 patients with various types of glomerulonephritis such as acute poststreptococcal glomerulonephritis, minimal lesion nephrotic syndrome and Henoch-Sch?lein purpura nephritis. 1) Serum IgG level was above normal mean in acute poststreptococcal glomerulonephritis, and normal range in Henoch-Scholein purpura nephritis. Serum IgG concentrations were significantly reduced in minimal lesion nephrotic syndrome. 2) Serum IgA concentrations...
Case Report
A Case of Acute Lymphocytic Leukemia with Both Renal Enlargement.
Choong Kil Chung, Jae Seung Lee, Byung Soo Kim
Clin Exp Pediatr. 1981;24(5):502-504.   Published online May 15, 1981
A case of acute lymphocytic leukemia with both renal enlargement found in a 2 3/12-year-old female has been presented. A brief review of the literatures was made on this subject.
Original Article
A Clinical and Pathological Study on the Treatment and Course of Purpura Nephritis in Chidren.
Jae Seung Lee, Sang Hak Park, Duk Hi Kim, Pyung Kil Kim, Duk Jin Yun, In Joon Choi
Clin Exp Pediatr. 1981;24(5):466-476.   Published online May 15, 1981
Purpura nephritis, one of the commonly known complications of allergic purpura has variable symptoms ranging from mild transient hematuria to severe nephrotic syndrome leading to renal failure and death. This paper reports on the treatment and course of purpura nephritis with special reference to serum immunoglobulins and immunopathology. These cases were selected among pediatric patients with purpura nephritis admitted to...
Case Report
Hepatorenal Syndrome.
Kyo Sun Kim, Young Mo Sohn, Jung Soo Kim, Jae Seung Lee, Pyung Kil Kim, Tae Jung Kwon, In Jun Choi
Clin Exp Pediatr. 1981;24(3):257-270.   Published online March 15, 1981
Hepatorenal syndrome is generally urged, at least until specific interrelationships between the two organs are confirmed by experimental and clinical data. Case I was a 11 year old boy, who had been suffered from acute fulminant viral hepatitis, which had developed acute hepatic necrosis associated with acute renal failure. Cass H was a 10 year old girl, who was performed corrective...
Double Kidneys, Double Ureters and Ureterocele in Identical Female Twins.
Ran Namkung, Do Kwang Yun, Jun Hee Sul, Jae Seung Lee, Pyung Kil Kim, Jin Moo Lee
Clin Exp Pediatr. 1981;24(2):145-152.   Published online February 15, 1981
We experienced a identical female twin with bilateral double kidneys, double ureters and ureterocele. Four month old baby was admitted due to high fever and irritability for 1 day. Her twin sister was also admitted two month later with the same problems. There were no abnormal findings on physical examination. Serial urinalysis revealed numerous white blood per high power field...
Original Article
Liver Abscess in Childhood.
Back Keun Lim, Hee Seon AuK, Kwan Sub Chung, Chang Ho Hong, Jae Seung Lee
Clin Exp Pediatr. 1980;23(12):999-1007.   Published online December 31, 1980
We have presented an analysis of cases of liver abscess from the record of the Department of Pediatrics, Yonsei medical College, during the 10 year 8 months period from Jan. 1969 through Sept. 1979. The incidence of admission in pediatric was 0.05025%. There was male preponderance. The most frequently encountered symptoms and sings were fever and chill, anorexia, hepatomegale, pain...
Case Report
The First Case of Renal Transplatation in Childhood in Korea.
Pyung Ki Kim, Chul Lee, Jae Seung Lee, Duk Jin Yun, Ki ll Park, Tae Jung Kwon, In Joon Choi
Clin Exp Pediatr. 1980;23(8):674-681.   Published online August 15, 1980
We successfully transplanted kidney of mother to 13 year old boy who had been suffered from chronic renal failure for 11 months. This is the first case of renal transplantation in childhood in Korea. Patient was treated chronic renal failure with peritoneal dialysis, hemodalysis and transfusion duing 1 month before transplantation. Both kidneys revealed grade 4 vesico-ureteral renal tissue by...
Original Article
I131 Rose Bengal Liver Scanning.
Chang Jun Coe, Jae Song Kim, Jae Seung Lee, Byung Soo Kim, Duk Jin Yun
Clin Exp Pediatr. 1977;20(8):613-620.   Published online August 31, 1977
This is a clinical study of I131 Rose Bengal liver scanning on 17 in-patients with jaundice hospitalized at Severance hospital from October 1969 to March 1976. And we observed following results. 1) In 13 patients, the liver scanning showed complete biliary obstructive pattern, in 2 patients partial obstruction and two had space occupying lesions. Of the 13 patients with complete...
Case Report
A Case of Mesenteric Lipoma.
Young Hoon Ahn, Tae Yeul Ma, Jae Seung Lee, Sun Huh
Clin Exp Pediatr. 1977;20(5):393-395.   Published online May 31, 1977
The mesenteric lipoma is rare in chilcren. A 2 years and 8 months old female child was admitted to department of Pediatrics in Inchon Christian Hospital on the 17 th Dec., 1974, because of abdominal distention and dyspnea. Operation revealed a soft yellowish mass, measuring 25x23x19cm. In size and 4,000gm. In weight. The pathologic diagnosis confirmed lipoma of the mesentery....
Original Article
Hemolytic-Uremic Syndrome
Jae Seung Lee, Chang Joon Ko, Duk Jin Yun, Yoo Bock Lee
Clin Exp Pediatr. 1972;15(4):326-331.   Published online April 30, 1972
Hemolytic-Uremic syndrome is a relatively new disease found in infants rather than in older children. The incidence of this disease has increased in recent years. Hemolytic-Uremic syndrome is a fatal illness characterized clinically by acute renal failure, thromboc- ytopenia and hemolytic anemia associated with distorted erythrocytes (Burr cells). A case of Hemolytic-Uremic syndrome in a 10 months old male patient diagnosed in 1970, the...
Case Report
Solitary Sessile Polypoid Cavernous Hemangioma of Sigmoid Colon(a case report)
Jung Ja Park, Chong Soo Kim, Jae Seung Lee, Jai Sung Lee, R.F. Roth
Clin Exp Pediatr. 1971;14(10):653-655.   Published online October 31, 1971
Hemangioma of the gastrointestinal tract is a rare disease. A case of solitary sessile polypoid cavernous hemangioma of sigmoid colon was found in a 7 year old female, and has been reported. The patient was improved after segmental resection and primary anastomosis of the sigmoid colon. A litereture review was made on this subject.
Original Article
Study of the Relationship Between Glucose Level in Cereberospinal Fluid and in Blood of Normal Children and Patients with Meningitis
Jae Seung Lee
Clin Exp Pediatr. 1971;14(10):644-652.   Published online October 31, 1971
Menigitis, despite the development of effective antibiotics, is still a disease o£ high mortality and morbidity in pediatrics(Light,1967). It is a disease attracting a great deal of attention by pediatricians. Sometimes meningitis in childhood shows atypical clinical symptoms and signs. The occurence of bacterial meningitis in the neonatal period and infants creates special problems in early diagnosis, because the signs...