Viral etiology is common in cases of children with acute diarrhea, and antibiotic therapy is usually not required. Therefore, it is important to determine the distribution of common viruses among children hospitalized with acute diarrhea. We included 186 children who suffered from acute diarrhea and were hospitalized at the Wonkwang University Hospital Pediatric ward from December 1, 2010 to June 30,... |
Purpose : Turner syndrome (TS) is a disorder in which various anomalies can be accompanied, especially cardiovascular, renal, thyroid and auditory problems. The aim of this study is to identify the incidence of these disorders in patients with TS according to karyotype. Methods : We reviewed medical records of 90 patients with TS diagnosed by chromosomal analysis in 4 hospitals... |
Purpose:We evaluated the effectiveness of treatment and cardiac complications of replacing a high dose of aspirin with a high dose of ibuprofen for children in acute phase of Kawasaki disease. We also analyzed the possibility of replacing a high dose of aspirin with a high dose of ibuprofen to prevent complications such as Reye s syndrome caused by aspirin. Methods:One hundred eight children... |
Purpose : This study was design and performed for evaluations of resent clinical pattern of bronchiolitis caused by RSV infection with children under 2 year of age for 5 years, who were admitted to pediatric ward. Methods : The inclusion criteria of the patients were children under 24 month-of-age, clinical manifestations of lower respiratory tract infection, and RSV antigen that... |
Hypothyroidism is a deficiency in thyroid hormone secretion by the thyroid gland and a defect in thyroid hormonal receptor activity. It is categorized by the two major forms in children, the one is congenital hypothyroidism and the other is acquired hypothyroidism. Congenital hypothyroidism is one of the commonest treatable causes of mental retardation and occurs in 1 in 3,000-4,000 infants... |
Purpose : IFNγ sentitizes many tumor cells to TNFα and FASL-mediated apoptosis by enhancing the expression of TNF or FAS/CD95 receptor and modulating the activation of caspase and Bcl-2 family. It has been reported that IFNγ and TNFα synergistically caused differentiation and growth inhibition of neuroblastoma cells. Even though some neuroblastoma cell express FASR/FASL on the cell surface, they could... |
Tsutsugamushi fever is a serious febrile disease outwardly similar to malaria and various arboviral infections. The endemic area is Asia-Pacific. This disease are generally associated with disturbed habitats favoring large populations of vector larval trombiculid mites. Therapy with tetracycline, chloramphenicol or ciprofloxacin is currently recommanded. Unfortunately these drugs is suboptimal for children and pregnant women. Recently, azithromycin has been proven... |
Purpose : Infants undergo critical and rapid stages of growth. Optimal nutrition during this period is therefore essential. Iron deficiency is especially impotant and common. The aim of this study was to determine the present status and problems of milk feeding methods in infants with iron deficiency anemia and, futhermore, to develop appropriate feeding guidelines for adequate iron nutrition. Latate is the end product... |
Purpose : Serum level of the aminotransferase is the most common test in use to assess hepatocellular injury and are sensitive test of hepatocyte necrosis, but both AST and ALT level in serum rise in a variety of hepatic disorders. Some clinical study reports that AST/ALT ratio was possible to predict prognostic outcome of infants with liver disease. We have tried to assess whether... |
Purpose : For evaluation of usefulness of the serum .2-microglobulin(B2MG), retinol binding protein(RBP), urine 1-microglobulin(A1MG), and B2MG on neonatal renal function and renal tubular injuries, we detected and compared these values in 20 neonates. Methods : They were grouped into premature neonate, gestational age was 30-50 weeks(group Ⅰ), and full term neonate, gestational age was 38-40 weeks(group Ⅱ), The group Ⅱ... |
To evaluate the risk and factors associated with seizure recurrence on children with epilepsy while receiving the adequate anticonvulsant treament, we studied 58 patients with newly diagnosed epilepsy who were followed prospectively for a median of 26 months (range 7 to 54). The results were as follows: 1) Forty-four of the 58 patients (75.9%)had recurrence... |
Basic experimental approach for rapid and acurate detection of respiratory syncitial virus (RSV) infection at gene level has been performed using polymerase chain reaction (PCR). RSV RNA was extracted by RNAzolB methol from RSV which was cultured in Hep-2 cell line. Of RSV genome having about 8,000 base pairs, base pairs between 3237th and 3522nd were selected to make four... |
When we are examining a cardiac patient, we want to make a physical diagnosis including involved ventricles, type of overload(volume or pressure), its degree, and the status or degree of pulmonary hypertension. Among various physical examinations of the cardiac patients, a left parasternal movement can give us a status of various degree of the volume and pressure overload of the ventricles.... |
The introduction of computerized tomography (CT), a diagnostic method, has revolutionized the evaluation of neurologic disorders in children. And it provides a noninvasive, safe, and rapid diagnosis of intracranial pathology. CT scanning was performed on 126 children with neurologic symptoms who had admitted to department of pediatrics, Wonkwang University Hospital, from January 1986 to June 1990. Our study was designed to evaluate the usefulness of... |
A Clinical study has been made on 33 cases of acute glomerulonephritis who were admitted to pediatric department of Won Kwang University Hospital, during 2 year period from Jan. 1985 to Dec. 1986 The results were as follows: 1) Male to female ratio was 1.4:1 and the age incidence was highest among children from 4 -12 years of age group(78.8%). 2) The most common season was... |
We have compared recurrent wheezing group with non-recurrent wheezing group of 91 cases on the aspects of clinical and laboratory findings, were admitted to the Department of Pediatrics, Won Kwang University Hospital with the impression of acute bronchiolitis from Jan. 1983 to Feb. 1986 The results were as follows; 1) The incidence of recurrent wheezing was 28.6%. 2) Sex incidence of recurrent wheezing was high in male.... |
We analyzed data on children with chronic renal failure collected from 36 pediatric training hospitals during the period from Jan. 1, 1980 to Dec. 31, 1984. The following results were obtained: 1) Total number of children with chronic renal failure during the study period was 135. The incidence was about 1 per 2,000 in-patients and 2.09 per million children under 15... |
One of the most frequently used anesthetics in the laboratory or clinical practice is barbiturate derivatives. There have been many reports on the renal effects of barbiturate anesthesia, but they still controversial. It has been reported that the central administration of very small dose of thiopental sodium influence the renal function directly. To compare possible different renal effects of the... |
In order to investigate the development of renal function, especially of the capacity of reabsorption of ascorbic acid in proximal tubule, in function of aging, experiments have been done. 1)Urinary flow, creatinine and electrolytes excretion in children (age :1~13yrs, weight: 10~39 kg) increased by aging and reached near the adult value at 11~13 years old. 2) Urinary concentration ability was matured... |