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Original Article
Molecular detection of Bartonella henselae DNA from fleas obtained from dogs, Korea
Tae Hee Han, Ju-Young Chung, Hee Kyung Seong, Sang Woo Kim
Clin Exp Pediatr. 2006;49(9):983-986.   Published online September 15, 2006
Purpose : The purpose of this study was to investigate the presence of Bartonella henselae DNA, which is known as an etiologic agent of lymphadenitis, in fleas from dogs. Methods : The Bartonella henselae infection was investigated in 42 fleas from 22 dogs in Korea. By using seminested PCR targeting pap31 gene, B. henselae DNA was amplified from fleas. Results :...
Histiocytic necrotizing lymphadenitis in children : association of human herpes virus 8 and Epstein Barr virus
Hyun A Kim, Ju-Young Chung, Sang Woo Kim, Sung Jig Lim, Haeng Seop Shin
Clin Exp Pediatr. 2006;49(8):875-881.   Published online August 15, 2006
Purpose : The aims of this study were to analyze the clinical characteristics of children with Kikuchi's disease(KD) at a medical center and to investigate the etiologic role of human herpesvirus 8(HHV 8) or Epstein-Barr virus(EBV) in children with KD. Methods : Twenty six children who were diagnosed as KD between Jan. 1998 and Dec. 2005 were included....
Case Report
A case of a child with non-parasitic chyluria
Da Eun Jung, Ja Wook Koo, Sang Woo Kim, Hae Il Cheong
Clin Exp Pediatr. 2006;49(3):326-328.   Published online March 15, 2006
Chyluria is the passage of milky urine due to the leakage of lymph into the urinary tract. Chyluria occurs predominantly in adults and is rare in children. We present an unusual case in which a child with proteinuria, hematuria and milky urine was subsequently diagnosed with non-parasitic chyluria. Retrograde cystogram confirmed a lymphatico-calyceal communication. This case showed spontaneous remission. The...
Original Article
Usefulness of serum procalcitonin test for the diagnosis of upper urinary tract infection in children
Dong Wook Kim, Ju Young Chung, Ja Wook Koo, Sang Woo Kim, Tae Hee Han
Clin Exp Pediatr. 2006;49(1):87-92.   Published online January 15, 2006
Purpose : It is difficult to make a distinction between lower urinary tract infection(UTI) and acute pyelonephritis(APN) during the acute phase of febrile UTI due to nonspecific clinical symptoms and laboratory findings, especially among young children. We measured the serum procalcitonin(PCT) in children with UTI to distinguish between acute pyelonephritis and lower UTI, and to determine the accuracy of PCT...
Trace element concentrations profiles in the hair of normal children living in the northern area of Seoul
Ji Won Kwon, Byung Eui Kim, Mi Jung Park, Sang Woo Kim
Clin Exp Pediatr. 2006;49(1):18-23.   Published online January 15, 2006
Purpose : The reliability of hair mineral analyses regarding nutritional status, environmental exposure or diseases is controversial. The aim of this study was to determine the normal reference range of hair mineral concentration of Korean children. Methods : We examined hair mineral concentrations of 223 children(3-12 yrs old, 110 boys, 113 girls, mean age 8.8?.2 yrs old) living in the...
Case Report
A Case of Cat Scratch Disease Confirmed by Polymerase Chain Reaction for Bartonella henselae DNA
Ju-Young Chung, Ja Wook Koo, Sang Woo Kim, Young Sam Yoo, Tae Hee Han, Seong Jig Lim
Clin Exp Pediatr. 2005;48(7):789-792.   Published online July 15, 2005
We report a case of cat scratch disease (CSD) caused by Bartonella henselae in a 14-year-old boy who developed lymphadenopathy in the right cervical area, after a raising canine pet for 10 months. The cervical lymphadenopathy persisted for 14 days. Immunofluorescent antibody testing for B. henselae with the patient's serum was 1:64 positive. Polymerase chain reaction (PCR) analysis using the...
Original Article
A Comparison of Clinical Manifestations in Neonates and Infants Infected by Respiratory Syncytial Virus
In Suk Lim, Min Joo Shim, Byung Eui Kim, Ju Young Chung, Chang Keun Kim, Myoung Jae Chey, Sang Woo Kim, Soung Hee Kim, Tae Hee Han
Clin Exp Pediatr. 2004;47(9):949-952.   Published online September 15, 2004
Purpose : This study was performed to evaluate of clinical manifestations of neonatal respiratory syncytial virus(RSV) infection, and to evaluate of differences of clinical manifestations between the neonates and infants who were infected by RSV. Methods : We reviewed the medical record of 75 children who were younger than 12 months of age and infected by RSV. We classified then into...
Case Report
Atypical Hemolytic Uremic Syndrome Associated with Streptococcus pneumoniae Infection
Hyun Sug Lee, Ja Wook Koo, Sang Woo Kim, Hyun Soon Lee
Clin Exp Pediatr. 2004;47(2):217-222.   Published online February 15, 2004
Hemolytic uremic syndrome is the most common cause of acute renal failure in childhood. Atypical hemolytic uremic syndrome which is not usually associated with prodromal symptoms has a higher mortality rate and more tendency to progress to chronic renal failure. Children younger than two years of age are a more susceptible to pneumococcal infection and can develop more serious disease....
A Case of 4q Deletion with Partial Agenesis of Corpus Callosum
Mi Na Kang, In Suk Lim, Byeong Eui Kim, Myoung Jae Chey, Sang Woo Kim
Clin Exp Pediatr. 2002;45(2):273-277.   Published online February 15, 2002
Syndrome of 4q deletion is characterized by an abnormal shape of the skull, craniofacial dysmorphism, cardiovascular malformations, genitourinary defects, limb and digital anomalies, and developmental delay. We experienced a case of 4q interstitial deletion in a 2 day-old female neonate who showed short extremities, partial agenesis of corpus callosum and congenital heart defects. We report the case with a brief...
A Case of Acute Necrotizing Encephalopathy
Sung Kee Kim, Se Wook Oh, Young Kyoun Kim, Se Chang Ham, Yong Won Park, Sang Woo Kim
Clin Exp Pediatr. 2001;44(8):954-958.   Published online August 15, 2001
This disease predominantly affects infants and young children living in Japan and Taiwan, and manifests itself as acute encephalopathy following viral infections. The hallmark of this encephalopathy is multifocal, symmetric brain lesions affecting bilateral thalamus, brainstem tegmentum, cerebral periventricular white matter and cerebellar medulla, which can be visualized by computed tomography and magnetic resonance imaging. Both the gray and white...
A Case of Branchio-Oto-Renal Syndrome
Sung Kee Kim, Young Gyun Kim, Se Chang Ham, Se Wook Oh, Yong Won Park, Sang Woo Kim
Clin Exp Pediatr. 2000;43(7):983-987.   Published online July 15, 2000
Branchio-oto-renal(BOR) syndrome is an autosomal dominant disorder. The pathophysiology of this syndrome is unknown. BOR syndrome has a wide range of clinical manifestations affecting the branchial, auditory and renal systems. Associated abnormalities of the face, lacrimal duct, palate and ureters have also been described. However, the major clinical findings associated and/ or ear pits, and renal anormaly. We experienced a case of a 15-day-old male...
Two Cases of Pelizaeus-Merzbacher Disease
Ho Seok Kang, Se Wook Oh, Yong Won Park, Chong Guk Lee, Sang Woo Kim, Ghi Jai Lee
Clin Exp Pediatr. 2000;43(4):561-566.   Published online April 15, 2000
Pelizaeus-Merzbacher disease(PMD) is a rare sudanophilic leukodystrophy with a reduced number of mature oligodendrocytes as well as diffuse central nervous system hypomyelination(dysmyelination) due to abnormal synthesis of proteolipid protein. PMD is characterized with pendular nystagmus, stridor, delay in psychomotor development, hypotonia, ataxia, athetosis and extrapyramidal signs. Abnormal high signal intensity is shown in the entire white matter of cerebrum and...
A Case of Partial Monosomy lOq Syndrome
Young Kyoun Kim, Yong Won Park, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1999;42(6):863-867.   Published online June 15, 1999
It has been estimated that chromosomal aberrations account for 2.3% to 3% of normal pregnancies and of them 85% are aborted. Therefore, the survival rate of neonates with chromosomal aberrations are very low. Patients with partial deletion of the long arm of chromosome 10 are rare. We experienced a case of partial monosomy 10 in a 14-years-old girl. She showed...
A Case of Bilateral Vocal Cord Paralysis in Neonate
Young Kyoun Kim, Seung Cheol Lee, Se Wook Oh, Sang Woo Kim, Jae Hyung Park
Clin Exp Pediatr. 1998;41(4):558-561.   Published online April 15, 1998
Neonatal vocal cord paralysis is the second most common laryngeal anomaly, which accounts for approximately 10% of all congenital laryngeal lesions. Neonate with bilateral vocal cord paralysis are charactenzed with a glottic obstruction which usually shows dyspnea and inspiratory stridor. Treatment of bilateral vocal cord paralysis in neonate have two major goals : restore proper breathing and retain the voice. Tracheostomy is the best...
A Case of Genital Prolapse in Premature Baby
Woong Kyu Choi, Seung Cheol Lee, Yong Won Park, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1998;41(2):281-284.   Published online February 15, 1998
Neonatal genital prolapse is very rare and is usually associated with meningomyelocele or other anomalies of the central nervous system. Synonyms of genital prolapse are sacropubic hernia, pelvic relaxation, and pelvic organ prolapse. There are two types of genital prolapse including vaginal prolapse and uterovaginal prolapse. We experienced a case of uterovaginal prolapse in a 30 day-old premature infant, which...
A Case of Lipoid Pneumonia with Hypercalcemia Caused by SqualelneⓇ Intake by Force
Young Kyoun Kim, Ho Suk Kang, Seung Cheol Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1997;40(12):1745-1749.   Published online December 15, 1997
Lipoid pneumonia is a chronic, interstitial, proliferative inflammation resulting from aspiration of lipoid material and occurs principally in debilated infants. We experienced a case of lipoid pneumonia with hypercalcemia in a 15 month-old boy who showed irritability, poor weight gain, cough, dyspnea, fatigue, diarrhea and pale face after ingestion of SqualeneⓇ(shark liver oil : 20-30 cap/day) by force for 2 months. Calcium preparation was also...
Clinical Lecture
Infant Nutrition
Sang Woo Kim
Clin Exp Pediatr. 1997;40(1):7-12.   Published online January 15, 1997
Original Article
The Correlation between CD34+ Cell and Nucleated RBC Counts in Human Cord Blood
Seong Man Lee, Kyu Chan Kim, Sang Woo Kim
Clin Exp Pediatr. 1996;39(10):1422-1428.   Published online October 15, 1996
Purpose : Human umbilical cord blood as a potential source of hematopoietic stem cell for stem cell transplantation in children has recently been advocated. Clinical application of cord blood transplantation, however, requires adequate blood volume and number of stem cells. Currently, the number of stem cells in the cord blood is usually measured by flowcytometry, which requires strict quality control and high costs. Here,...
Case Report
A Case of Spinal Epidural Hematoma due to Arteriovenous Malformation
Yoon Hee Lee, Se Wook Oh, Sang Woo Kim, Yi Kyeong Chun
Clin Exp Pediatr. 1996;39(3):436-440.   Published online March 15, 1996
Spinal epidural hematoma results from various causes such as use of anticoagulants, hemorrhagic diathesis, pregnancy, labor, arteriovenous malformation and spinal anesthesia as well as idiopathic orgin. We report a 3-year-old boy who was found to have spinal epidural hematoma and presented with lower back pain and fever. He developed paraplegia of lower legs after two consecutive lumbar punctures during two days....
A Case of Hypothalamic Hamartoma with Gelastic Seizure Only
Se Wook Oh, Je Ho Cho, Sang Woo Kim
Clin Exp Pediatr. 1996;39(3):431-435.   Published online March 15, 1996
Hypothalamic hamartoma is a congenital anomaly presenting precocious puberty, gelastic seizure and mental retardation. Other possible accompanying anomalies are cleft palate, tetralogy of Fallot, skeletal malformation and anal malformation. But the patient describing here manifested gelastic seizure only with isosignal mass of 1.5cm in diameter situated just behind optic chiasm in T1WI and T2WI of MRI. His EEG showed multifocal...
Original Article
Clinical Study of Subarterial Ventricular Septal Defect
Yon Sook Rho, Yong Won Park, Sang Woo Kim, Bon Il Ku, Sang Joon Oh, Hong Sup Lee, Chang Ho Kim
Clin Exp Pediatr. 1995;38(4):493-500.   Published online April 15, 1995
Purpose : The incidence of subarterial ventricular septal defect(SA VSD) ranges 25-30% among oriental patients with VSDs, which is greater than 5% reported in western. Natural history of the disease is characterized by progressive aortic valve prolapse(AVP), frequently subarterial VSD, we evaluated clinical characteristics emphasizing on the incidence of AVP and the degree of AI as aging. Methods : Study subjects...
Case Report
A Case of Remission of Systemic Juvenile Rheumatoid Arthritis (Still's Disease) Treated with High-dose Intravenous Gammaglobulin
Yon Sook Rho, Yun Woo Lee, Sang woo Kim
Clin Exp Pediatr. 1994;37(12):1767-1772.   Published online December 15, 1994
High dose intravenous gammaglobuline (IVIG) therapy is effective in some of the autoimmune diseases. Although the exact mechamism of action of IVIG is uncertain, the action as a neutralizing antibody against unknown etiologic agents, the action of blocking of Fc receptors of effector cells, or the action as a antiidiotypic antibody are suggested. We report a case of 12 year old...
Original Article
The Effect of Cranial Irradiation on Growth of Children with Lymphatic Origin Tumors
Jin Seoup Jung, Yon Sook Rho, Sang Woo Kim
Clin Exp Pediatr. 1994;37(5):666-671.   Published online May 15, 1994
A retrospective study was conducted to investigate the effects of CNS prophylaxis with 1,800cGy cranial irradiation on standing height growth of children with acute lymphoblastic leukemia(ALL). Seventeen longterm survivors (DFS over 5 years) of ALL and Non-Hodgkins Lymphoma who had been admitted at pediatric department of Inje University Seoul Paik Hospital from January 1982 to September 1988 were studied. The long term...
Case Report
A Case of Chronic Recurrent Obstructive Bronchitis Associated with Gastro-Esophageal Reflux
Myung Hee Min, Sang Soo Roh, Sang Il Lee, Sang Woo Kim
Clin Exp Pediatr. 1992;35(4):556-562.   Published online April 15, 1992
It has been well established that the gastroesophageal reflux and chronic respiratory problem were closely related. Several reports in pediatric literature have implicated the aspiration of gasrtric contents as a trigger factor of cough, wheezing, and recurrent pulmonary disease. Several possible mechanisms have been proposed whereby acidic gastric content can trigger bronchospasm and, in turn, bronchospams can trigger gastroesopohageal reflux. Several tests,...
A Case of Leigh's Disease
Il Jung Joo, Hyun Cheol Hwang, Sang Woo Kim, Yong Seung Hwang
Clin Exp Pediatr. 1992;35(2):234-239.   Published online February 15, 1992
We experienced a case of Leigh's disease (subacute necrotizing encephalomyelopathy) in a 3-year old boy who was presented with hypertension and showed progressive respiratory arrest after giving chloral hydrate or ketamine. Almost all diagnostic tests including brain CT showed normal findings. The diagnosis could be made by MRI and TFCA (Transfemoral carotid angiography). A review of literature was also made...
Original Article
A clinical study of pneumonia presented with positive cold agglutin- in test.
Il Jung Joo, Jin Seop Juong, Sang Woo Kim
Clin Exp Pediatr. 1991;34(8):1093-1101.   Published online August 31, 1991
A clinical study was performed on 65 patients with Mycoplasma pneumoniae pneumonia who were admitted to the Department of Pediatrics of Seoul Paik hospital from September 1,1989 to August 31, 1990. The results were as follows; 1) Seasonal distribution showed a high frequency in summer (33 cases; 50.8%). 2) The peak incidence was 5 to 9 years of age (32cases;49.2%). 3) Male to female ratio was 1:1.17(30:35). 4) On the chest...
A case of neonatal cold injury.
Bub Seong Kim, Sang Soo Rho, Young Il Park, Sang Woo Kim
Clin Exp Pediatr. 1991;34(3):404-407.   Published online March 31, 1991
We experienced a case of neonatal cold injury, who initially showed CNS depression, respiratory depression, hyperglycemia and acidosis, followed by hypoglycemia, seizure and respiratory distress during the recovery phase treated with rewarming. A brief review of literature was made.
A Case of Hemolytic Uremic Syndrome.
Seung Cheol Lee, Chong Guk Lee, Seong Hwan Kim, Sang Woo Kim, Hyun Soon Lee
Clin Exp Pediatr. 1990;33(8):1140-1147.   Published online August 31, 1990
A female child aged 7 months was admitted because of high fever, vomiting and stuporous conciousness and revealed to have hemolytic uremic syndrome. Anuria persisted 13 days and required peritoneal dialysis 4 times a day during the anuric period. Her kidney function recovered somewhat after dialysis but neurologic complications of marked hydrocephalus and brain atrophy remained.
An Experience of High Dose Intravenous Immunoglobulin Therapy in Refractory Evans Syndrome.
Hee Sup Kim, Won Sup Shin, Sang Il Lee, Sang Woo Kim
Clin Exp Pediatr. 1990;33(5):701-707.   Published online May 31, 1990
Evans syndrome, a combination of autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura, relapses freguently and is refractory to conventional treatment such as corticosteroid, immunosuppressive agents, splenectomy and plasma exchange. Recently Oda et al applied high dose immunoglobulin (400/kg/day for 4 days repeated 2 weeks later) to 5 month-old infant with refractory Evans syndrome, and was successful in maintaining remission for five years and nine...
A case of Kostmann syndrome.
Won Sup Shin, Sang Woo Kim, In Kee Paik
Clin Exp Pediatr. 1989;32(11):1568-1573.   Published online November 30, 1989
Kostmann Syndrome is an uncommon disorder, which is characterized by recurring infections, begining soon after birth, arid by abscence of granulocyte in the peripheral blood. The authors experienced a case of Kostmann Syndrome in a 5 months old boy who had suffered from recurrent infection since 7 days of age. We diagnosed this case by history, physical examina- tions, culture of bone marrow stem...