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Original Article
Neurology
The clinical characteristics and prognosis of subgaleal hemorrhage in newborn
Sun Jin Lee, Jin Kyu Kim, Sun Jun Kim
Clin Exp Pediatr. 2018;61(12):387-391.   Published online September 16, 2018

Purpose: Subgaleal hemorrhage (SGH) is a rare but potentially fatal condition in newborns; however, few studies have reported on this condition. We aimed to identify the clinical characteristics and prognostic factors of SGH. Methods: We retrospectively reviewed the medical records of 20 neonates diagnosed with SGH between January 2000 and June 2017. Enrolled neonates were clinically diagnosed when they had tender...
Clinical characteristics of hypertensive encephalopathy in pediatric patients
Chang Hoon Ahn, Seung-A Han, Young Hwa Kong, Sun Jun Kim
Clin Exp Pediatr. 2017;60(8):266-271.   Published online August 14, 2017
Purpose

The aim of this study was to assess the clinical characteristics of hypertensive encephalopathy according to the underlying etiologies in children.

Methods

We retrospectively evaluated 33 pediatric patients who were diagnosed as having hypertensive encephalopathy in Chonbuk National University Children's Hospital. Among the patients, 18 were excluded because of incomplete data or because brain magnetic resonance imaging (MRI) was not performed. Finally,...

Effects of low-dose topiramate on language function in children with migraine
Seung-A Han, Eu Jeen Yang, Younghwa Kong, Chan-Uhng Joo, Sun Jun Kim
Clin Exp Pediatr. 2017;60(7):227-231.   Published online July 31, 2017
Purpose

This study aimed to verify the safety of low-dose topiramate on language development in pediatric patients with migraine.

Methods

Thirty newly diagnosed pediatric patients with migraine who needed topiramate were enrolled and assessed twice with standard language tests, including the Test of Language Problem Solving Abilities (TOPs), Receptive and Expressive Vocabulary Test, Urimal Test of Articulation and Phonology, and computerized speech laboratory...

Effects of lamotrigine on attention-deficit hyperactivity disorder in pediatric epilepsy patients
Seung-A Han, Eu Jeen Yang, Mi-Kyoung Song, Sun Jun Kim
Clin Exp Pediatr. 2017;60(6):189-195.   Published online June 22, 2017
Purpose

The purpose of this study was to investigate the effects of lamotrigine for the treatment of attention-deficit hyperactivity disorder (ADHD) symptoms in children with epilepsy.

Methods

Pediatric patients newly diagnosed with epilepsy (n=90 [61 boys and 29 girls]; mean age, 9.1±3.4 years) were enrolled. All patients were evaluated with the Korean ADHD rating scale (K-ARS)-IV before treatment with lamotrigine and after doses...

Ultrasound-guided internal jugular vein catheterization in critically ill pediatric patients
Eu Jeen Yang, Hyeong Seok Ha, Young Hwa Kong, Sun Jun Kim
Clin Exp Pediatr. 2015;58(4):136-141.   Published online April 22, 2015
Purpose

Continuous intravenous access is imperative in emergency situations. Ultrasound-guided internal jugular vein (IJV) catheterization was investigated in critically ill pediatric patients to assess the feasibility of the procedure.

Methods

Patients admitted to the pediatric intensive care unit between February 2011 and September 2012 were enrolled in this study. All patients received a central venous catheter from attending house staff under ultrasound guidance....

Korean speech sound development in children from bilingual Japanese-Korean environments
Jeoung Suk Kim, Jun Ho Lee, Yoon Mi Choi, Hyun Gi Kim, Sung Hwan Kim, Min Kyung Lee, Sun Jun Kim
Clin Exp Pediatr. 2010;53(9):834-839.   Published online September 13, 2010
Purpose

This study investigates Korean speech sound development, including articulatory error patterns, among the Japanese-Korean children whose mothers are Japanese immigrants to Korea.

Methods

The subjects were 28 Japanese-Korean children with normal development born to Japanese women immigrants who lived in Jeonbuk province, Korea. They were assessed through Computerized Speech Lab 4500. The control group consisted of 15 Korean children who lived in...

Clinical efficacy and safety of lamotrigine monotherapy in newly diagnosed pediatric patients with epilepsy
Ji Hye Han, Jung Eun Oh, Sun Jun Kim
Clin Exp Pediatr. 2010;53(4):565-570.   Published online April 15, 2010
Purpose : To verify the efficacy and safety of lamotrigine (LTG) monotherapy in newly diagnosed children with epilepsy. Methods : We prospectively enrolled 148 children who had undergone LTG monotherapy at our institution between September 2002 and June 2009. Twenty-nine patients were excluded: 19 due to incomplete data and 10 were lost to follow up. The data of the remaining...
Acoustic variations associated with congenital heart disease
Jung Eun Oh, Yoon Mi Choi, Sun Jun Kim, Chan Uhng Joo
Clin Exp Pediatr. 2010;53(2):190-194.   Published online February 15, 2010
Purpose : To investigate the nature of deviant voice physiology in preoperative children with congenital heart disease. Methods : Ninety-four children with congenital heart disease were enrolled. Their cries and related acoustic variables (fundamental frequency, duration, noise to harmonic ratio, jitter￠￢ and shimmer) were analyzed using a multi-dimensional voice program. Results : The average fundamental frequency showed a significant decrease in patent...
Study of sedation according to neurologic and non-neurologic pediatric patients
Jeong Hwa Kim, Min Seon Kim, Dae-Yeol Lee, Sun Jun Kim
Clin Exp Pediatr. 2008;51(10):1047-1051.   Published online October 15, 2008
Purpose : This study aims to evaluate the efficacy and safety of sedatives for pediatric patients using noninvasive procedures. Methods : We performed a prospective study in 446 (aged 1 month-21 y) consecutive pediatric patients undergoing sedation to study noninvasive sedation techniques from February to August 2007. We reviewed demographic data, sedative drugs, dosage, complications, and successful rates of sedation...
Acoustic differences according to the epileptic focus in benign partial epilepsy with centrotemporal spikes patients
Jung Tae Kim, Sang Hoon Choi, Sun Jun Kim
Clin Exp Pediatr. 2007;50(9):896-900.   Published online September 15, 2007
Purpose : The aim of this study was to investigate the speech problems in benign rolandic epilepsy (BRE) according to the seizure focus in EEG and semiology. Methods : Twenty three patients [right origin (13 patients) or left side (10 patients)] who met the BRE criteria by International League Against Epilepsy (ILAE) were prospectively enrolled. We excluded the patients who...
Case Report
Joubert syndrome with peripheral dysostosis - A case report of long term follow-up -
Jung Tae Kim, Sun Jun Kim, Chan-Uhng Joo, Soo Chul Cho, Dae-Youl Lee
Clin Exp Pediatr. 2007;50(3):315-318.   Published online March 15, 2007
This report describes the long-term follow-up of a 10-year-old female patient with Joubert syndrome with short stature and brachydactyly. She presented with hyperpnea alternated with hypopnea, uncontrolled jerking eye movements, and hypotonia during early infancy. She was diagnosed with Joubert syndrome based on clinical symptoms and typical MRI findings at 5 months of age. Abnormal ventilation and eye movements disappeared...
Original Article
Predictive value of cobalt chloride solution for hypohidrosis with topiramate
Hyuk Lee, Seung Hyun Lee, Sun Jun Kim
Clin Exp Pediatr. 2006;49(11):1180-1185.   Published online November 15, 2006
Purpose : The aims of this study were to verify the incidence of hypohidrosis and to determine the predictive value of noninvasive indicator test (NeurocheckTM) for sweating after administration of topiramate in newly diagnosed pediatric epileptic patients. Methods : A total of 46 epileptic patients (22 boys; 24 girls) on topiramate treatment were evaluated in this study at the Department...
Changes of Body Weight and Lipid Profiles According to Apolipoprotein E Polymorphism in Children with Antiepileptics
Seung Hee Jang, Eun Kyoung Choi, So Hee Eun, Sun Jun Kim
Clin Exp Pediatr. 2002;45(1):88-94.   Published online January 15, 2002
Purpose : Weight changes, especially weight gain, is a side effect of antiepileptics(especially valproate and carbamazepine). This may be sufficiently severe to cause noncompliance or to require the withdrawal of effective treatment. Unfortunately, the exact mechanism of weight change is not illustrated. Several reports and our experiment suggested that weight gain highly correlated with a familial tendency of obesity. The genetic makeup is a...
The Changes of Biochemical Bone Markers in Pediatric Epileptic Children Who Received Long-term Antiepileptic Drugs and Usefullness Thereof
Eun Kyung Choi, Kyung Hee Kim, Sun Jun Kim
Clin Exp Pediatr. 2001;44(7):778-785.   Published online July 15, 2001
Purpose : Long-term administration of anticonvulsants for pediatric epileptic patients may cause changes of bone metabolism. This study was performed to evaluate the influence of antiepileptics on the bone metabolism and growth in pediatric patients who received antiepileptics. Methods for early detection of adverse bone metabolism were also evaluated. Methods : Forty-eight epileptic patients were enrolled in this study....
Apolipoprotein E Polymorphism and Plasma Lipid Levels in Obese Children
Myoung Hee Han, Sun Jun Kim
Clin Exp Pediatr. 2000;43(5):679-685.   Published online May 15, 2000
Purpose : The increased prevalence of dyslipoproteinemia in obese children probably contributes to the high risk of cardiovascular disease associated with being overweight. The genetic makeup is possible one of the factors that influence the impact of obesity on lipid metabolism. A relation between apolipoprotein E(Apo E) polymorphism and lipid metabolism has been convincingly demonstrated in large population. The purpose...
Effect of Antiepileptic Drugs on Bone Metabolism and Growth in Epileptic Children
Woo Suk Juhng, Sun Jun Kim, Soo Chul Cho, Chan Uhng Joo
Clin Exp Pediatr. 1999;42(8):1078-1085.   Published online August 15, 1999
Purpose : Long-term administration of anticonvulsants for children with convulsive disorder may cause osteomalacia, depending on dosage, duration, types, and combination of anticonvulsants administered. This study was performed to examine the effect of anticonvulsant drugs on bone mineral density in epileptic children. Methods : Forty-eight epileptic children aged 3 to 15 years were enrolled in this study. They were treated with...
Changes of Anti-H.influenzae Type b IgG in the Sera of Korean Infants and Children after Birt
Jong Man Park, Keoung Hie Moon, Kyung Mee Lee, Sun Jun Kim, Soo Chul Cho, Jung Soo Kim
Clin Exp Pediatr. 1997;40(2):181-188.   Published online February 15, 1997
Purpose : Most of invasive Haemophilus influenzae diseases occur in children under 5 years of age, and are due almost exclusively to type b strain. Although antibodies to several surface antigens of H.influenzae play a role in conferring immunity, antibody to the type b capsular polysaccharide appeared to have the most important protective functions. However, the antibody response to vaccines or natural...
Auditory Evoked Potentials in Fullterm Infants with Birth Asphyxia and Premature Infants
Ha Shin Park, Myung Suk Song, Sun Jun Kim, Hea Jin Choeh, Kyu Chul Choeh
Clin Exp Pediatr. 1995;38(8):1054-1060.   Published online August 15, 1995
Purpose : Auditory evoked potentials(AEP) are sensitive electrophysiological technique which accurately assesses the functional integrity of the auditory pathway in the brainstem. As a test of brainstem function, AEP have the advantages that the procedure is standardized, the results are reproducible, the norms for neonated have been estsblished, and the equipment to perform the test is widely available. Our study...
Systolic Pressure Amplification of the Aortic Pressure in Children with Congenital Heart Disease
Chan Uhng Joo, Byoung Geun Lee, Sun Jun Kim, Jung Soo Kim
Clin Exp Pediatr. 1993;36(2):232-238.   Published online February 15, 1993
Direct intraarterial measurement of blood pressure is an important diagnostic procedure in critical patients and premature baby care. Direct measurement was more accepted and confident method in physician than the indirect methods. But the presence of a significant amplification of systolic pressure in peripheral artery may lead to important error. So we have investigated the degree of the systolic pressure...
Changes of Plasma Atrial Natriuretic Peptide and Antidiuretic Hormone in Congenital Heart Disease.
Sun Jun Kim, Jong San Lee, Chan Uhng Joo, Dae Yeol Lee, Jung Soo Kim
Clin Exp Pediatr. 1989;32(8):1106-1116.   Published online August 31, 1989
Human atrial myocytes secrete atrial natriuretic peptides (ANP) into the plasma, which causes rapid and marked natriuresis, diuresis and vasorelaxation. The releases of renin, aldosterone, and antidiuretic hormone are inhibited by ANP in vivo and in vitro experiments. Various atrial natriur- etic peptides were isolated and synthesized. Plasma ANP concentrations usually elevated in conges- tive heart failure, chronic renal failure, pulmonary arterial hypertension, tachyarrhythmia,...
Effect of Adriamycin on Lipid Metabolismin Rats.
Chang Beom Shin, Sun Jun Kim, Chan Unng Joo, Dae Yeol Lee, Jung Soo Kim
Clin Exp Pediatr. 1988;31(9):1133-1138.   Published online September 30, 1988
This experiment was carried out to investigate the disturbance of lipid metabolism after long-term administration of adriamycin in rats (2.5 mg/kg/week for 5 weeks, S.C.). Changes of Serum lipids, GOT, GPT, LDH, albumin, BUN, and creatinine were investigated after administration of adriamycin. Clinical findings of congestive heart failure and changes of body weight were also observed during experiment. The results were as follows; 1) Serum triglyceride, total cholesterol,...